{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T13:25:19Z","timestamp":1768742719302,"version":"3.49.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2016,11,22]],"date-time":"2016-11-22T00:00:00Z","timestamp":1479772800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2016,11,22]],"date-time":"2016-11-22T00:00:00Z","timestamp":1479772800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In a familiar city, people can recall scene views (e.g., a particular street corner scene) they could encounter again in the future. Complex objects with multiple features are represented by multiple neural units (channels) in the brain, but when anticipating a scene view, the kind of feature that is assigned to a specific channel is unknown. Here, we studied neural encoding of scene view anticipation during spatial navigation, using a novel data-driven analysis to evaluate encoding channels. Our encoding models, based on functional magnetic resonance imaging (fMRI) activity, provided channel error correction via redundant channel assignments that reflected the navigation environment. We also found that our encoding models strongly reflected brain activity in the inferior parietal gyrus and precuneus, and that details of future scenes were locally represented in the superior prefrontal gyrus and temporal pole. Furthermore, a decoder associated with the encoding models accurately predicted future scene views in both passive and active navigation. These results suggest that the human brain uses scene anticipation, mediated especially by parietal and medial prefrontal cortical areas, as a robust and effective navigation processing.<\/jats:p>","DOI":"10.1038\/srep37599","type":"journal-article","created":{"date-parts":[[2016,11,22]],"date-time":"2016-11-22T10:10:32Z","timestamp":1479809432000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Robust encoding of scene anticipation during human spatial navigation"],"prefix":"10.1038","volume":"6","author":[{"given":"Yumi","family":"Shikauchi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shin","family":"Ishii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,11,22]]},"reference":[{"key":"BFsrep37599_CR1","doi-asserted-by":"publisher","first-page":"832","DOI":"10.1038\/90547","volume":"4","author":"K Tsunoda","year":"2001","unstructured":"Tsunoda, K., Yamane, Y., Nishizaki, M. & Tanifuji, M. Complex objects are represented in macaque inferotemporal cortex by the combination of feature columns. Nat. Neurosci. 4, 832\u2013838 (2001).","journal-title":"Nat. Neurosci."},{"key":"BFsrep37599_CR2","doi-asserted-by":"publisher","first-page":"17648","DOI":"10.1038\/srep17648","volume":"5","author":"Y Shikauchi","year":"2015","unstructured":"Shikauchi, Y. & Ishii, S. Decoding the view expectation during learned maze navigation from human fronto-parietal network. Sci. Rep. 5, 17648 (2015).","journal-title":"Sci. Rep"},{"key":"BFsrep37599_CR3","doi-asserted-by":"publisher","first-page":"915","DOI":"10.1016\/j.neuron.2008.11.004","volume":"60","author":"Y Miyawaki","year":"2008","unstructured":"Miyawaki, Y. et al. Visual image reconstruction from human brain activity using a combination of multiscale local image decoders. Neuron 60, 915\u2013929 (2008).","journal-title":"Neuron"},{"key":"BFsrep37599_CR4","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1016\/j.neuron.2013.06.034","volume":"79","author":"DE Stansbury","year":"2013","unstructured":"Stansbury, D. E., Naselaris, T. & Gallant, J. L. Natural scene statistics account for the representation of scene categories in human visual cortex. Neuron 79, 1025\u20131034 (2013).","journal-title":"Neuron"},{"key":"BFsrep37599_CR5","doi-asserted-by":"publisher","first-page":"1641","DOI":"10.1016\/j.cub.2011.08.031","volume":"21","author":"S Nishimoto","year":"2011","unstructured":"Nishimoto, S. et al. Reconstructing visual experiences from brain activity evoked by natural movies. Curr. Biol. 21, 1641\u20131646 (2011).","journal-title":"Curr. Biol."},{"key":"BFsrep37599_CR6","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1126\/science.1234330","volume":"340","author":"T Horikawa","year":"2013","unstructured":"Horikawa, T., Tamaki, M., Miyawaki, Y. & Kamitani, Y. Neural decoding of visual imagery during sleep. Science 340, 639\u2013642 (2013).","journal-title":"Science"},{"key":"BFsrep37599_CR7","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1016\/j.neuroimage.2010.07.073","volume":"56","author":"T Naselaris","year":"2011","unstructured":"Naselaris, T., Kay, K. N., Nishimoto, S. & Gallant, J. L. Encoding and decoding in fMRI. Neuroimage 56, 400\u2013410 (2011).","journal-title":"Neuroimage"},{"key":"BFsrep37599_CR8","doi-asserted-by":"publisher","first-page":"1075","DOI":"10.1016\/j.conb.2012.08.003","volume":"22","author":"BB Doll","year":"2012","unstructured":"Doll, B. B., Simon, D. A. & Daw, N. D. The ubiquity of model-based reinforcement learning. Curr. Opin. Neurobiol. 22, 1075\u20131081 (2012).","journal-title":"Curr. Opin. Neurobiol."},{"key":"BFsrep37599_CR9","first-page":"181","volume":"38","author":"PJ Boland","year":"1989","unstructured":"Boland, P. J. Majority Systems and the Condorcet Jury Theorem. Stat. 38, 181 (1989).","journal-title":"Stat."},{"key":"BFsrep37599_CR10","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1613\/jair.105","volume":"2","author":"TG Dietterich","year":"1995","unstructured":"Dietterich, T. G. & Bakiri, G. Solving multiclass learning problems via error-correcting output codes. J. Artif. Intell. Res. 2, 263\u2013286 (1995).","journal-title":"J. Artif. Intell. Res."},{"key":"BFsrep37599_CR11","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1109\/TCBB.2007.70239","volume":"6","author":"N Yukinawa","year":"2009","unstructured":"Yukinawa, N., Oba, S., Kato, K. & Ishii, S. Optimal aggregation of binary classifiers for multiclass cancer diagnosis using gene expression profiles. IEEE\/ACM Trans. Comput. Biol. Bioinform. 6, 333\u2013343 (2009).","journal-title":"IEEE\/ACM Trans. Comput. Biol. Bioinform"},{"key":"BFsrep37599_CR12","doi-asserted-by":"publisher","first-page":"2049","DOI":"10.1162\/neco.2009.03-08-740","volume":"21","author":"T Takenouchi","year":"2009","unstructured":"Takenouchi, T. & Ishii, S. A multiclass classification method based on decoding of binary classifiers. Neural Comput. 21, 2049\u20132081 (2009).","journal-title":"Neural Comput."},{"key":"BFsrep37599_CR13","doi-asserted-by":"publisher","first-page":"2181","DOI":"10.1038\/ncomms3181","volume":"4","author":"DJ Bakkum","year":"2013","unstructured":"Bakkum, D. J. et al. Tracking axonal action potential propagation on a high-density microelectrode array across hundreds of sites. Nat. Commun. 4, 2181, doi: 10.1038\/ncomms3181 (2013).","journal-title":"Nat. Commun."},{"key":"BFsrep37599_CR14","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1037\/0033-2909.116.2.220","volume":"116","author":"H Pashler","year":"1994","unstructured":"Pashler, H. Dual-task interference in simple tasks: Data and theory. Psychol. Bull. 116, 220\u2013244 (1994).","journal-title":"Psychol. Bull."},{"key":"BFsrep37599_CR15","doi-asserted-by":"publisher","first-page":"7585","DOI":"10.1523\/JNEUROSCI.0948-08.2008","volume":"28","author":"M Sigman","year":"2008","unstructured":"Sigman, M. & Dehaene, S. Brain mechanisms of serial and parallel processing during dual-task performance. J. Neurosci. 28, 7585\u20137598 (2008).","journal-title":"J. Neurosci."},{"key":"BFsrep37599_CR16","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1038\/nature14396","volume":"522","author":"HT Ito","year":"2015","unstructured":"Ito, H. T., Zhang, S.-J., Witter, M. P., Moser, E. I. & Moser, M.-B. A prefrontal\u2013thalamo\u2013hippocampal circuit for goal-directed spatial navigation. Nature 522, 50\u201355 (2015).","journal-title":"Nature"},{"key":"BFsrep37599_CR17","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1038\/nn.3649","volume":"17","author":"BKH Chau","year":"2014","unstructured":"Chau, B. K. H., Kolling, N., Hunt, L. T., Walton, M. E. & Rushworth, M. F. S. A neural mechanism underlying failure of optimal choice with multiple alternatives. Nat. Neurosci. 17, 463\u2013470 (2014).","journal-title":"Nat. Neurosci."},{"key":"BFsrep37599_CR18","doi-asserted-by":"publisher","first-page":"20547","DOI":"10.1073\/pnas.1012246107","volume":"107","author":"MP Noonan","year":"2010","unstructured":"Noonan, M. P. et al. Separate value comparison and learning mechanisms in macaque medial and lateral orbitofrontal cortex. Proc. Natl. Acad. Sci. USA 107, 20547\u201320552 (2010).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFsrep37599_CR19","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1038\/nn.3017","volume":"15","author":"LT Hunt","year":"2012","unstructured":"Hunt, L. T. et al. Mechanisms underlying cortical activity during value-guided choice. Nat. Neurosci. 15, 470\u2013476 (2012).","journal-title":"Nat. Neurosci."},{"key":"BFsrep37599_CR20","doi-asserted-by":"publisher","first-page":"12176","DOI":"10.1523\/JNEUROSCI.3761-07.2007","volume":"27","author":"A Johnson","year":"2007","unstructured":"Johnson, A. & Redish, A. D. Neural ensembles in CA3 transiently encode paths forward of the animal at a decision point. J. Neurosci. 27, 12176\u201312189 (2007).","journal-title":"J. Neurosci."},{"key":"BFsrep37599_CR21","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1016\/j.neuron.2007.04.006","volume":"54","author":"S Park","year":"2007","unstructured":"Park, S., Intraub, H., Yi, D.-J., Widders, D. & Chun, M. M. Beyond the edges of a view: boundary extension in human scene-selective visual cortex. Neuron 54, 335\u2013342 (2007).","journal-title":"Neuron"},{"key":"BFsrep37599_CR22","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1002\/hipo.10173","volume":"14","author":"AS Etienne","year":"2004","unstructured":"Etienne, A. S. & Jeffery, K. J. Path integration in mammals. Hippocampus 14, 180\u2013192 (2004).","journal-title":"Hippocampus"},{"key":"BFsrep37599_CR23","doi-asserted-by":"publisher","first-page":"1210","DOI":"10.1016\/j.neuron.2012.10.014","volume":"76","author":"AG Huth","year":"2012","unstructured":"Huth, A. G., Nishimoto, S., Vu, A. T. & Gallant, J. L. A continuous semantic space describes the representation of thousands of object and action categories across the human brain. Neuron 76, 1210\u20131224 (2012).","journal-title":"Neuron"},{"key":"BFsrep37599_CR24","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1038\/nn.3381","volume":"16","author":"T \u00c7ukur","year":"2013","unstructured":"\u00c7ukur, T., Nishimoto, S., Huth, A. G. & Gallant, J. L. Attention during natural vision warps semantic representation across the human brain. Nat. Neurosci. 16, 763\u2013770 (2013).","journal-title":"Nat. Neurosci."},{"key":"BFsrep37599_CR25","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1016\/j.tins.2004.10.007","volume":"27","author":"DC Knill","year":"2004","unstructured":"Knill, D. C. & Pouget, A. The Bayesian brain: the role of uncertainty in neural coding and computation. Trends Neurosci. 27, 712\u2013719 (2004).","journal-title":"Trends Neurosci."},{"key":"BFsrep37599_CR26","doi-asserted-by":"crossref","unstructured":"Doya, K., Ishii, S., Pouget, A. & Rao, R. P. N. Bayesian Brain: Probabilistic Approaches to Neural Coding. (The MIT Press, 2006).","DOI":"10.7551\/mitpress\/9780262042383.001.0001"},{"key":"BFsrep37599_CR27","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/j.tics.2006.05.003","volume":"10","author":"KP K\u00f6rding","year":"2006","unstructured":"K\u00f6rding, K. P. & Wolpert, D. M. Bayesian decision theory in sensorimotor control. Trends Cogn. Sci. 10, 319\u2013326 (2006).","journal-title":"Trends Cogn. Sci."},{"key":"BFsrep37599_CR28","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1038\/nature09633","volume":"469","author":"G Dragoi","year":"2011","unstructured":"Dragoi, G. & Tonegawa, S. Preplay of future place cell sequences by hippocampal cellular assemblies. Nature 469, 397\u2013401 (2011).","journal-title":"Nature"},{"key":"BFsrep37599_CR29","first-page":"81","volume":"1","author":"JR Quinlan","year":"1986","unstructured":"Quinlan, J. R. Induction of decision trees. Mach. Learn. 1, 81\u2013106 (1986).","journal-title":"Mach. Learn."},{"key":"BFsrep37599_CR30","doi-asserted-by":"publisher","first-page":"818","DOI":"10.1016\/j.neuroimage.2009.11.084","volume":"50","author":"L Reddy","year":"2010","unstructured":"Reddy, L., Tsuchiya, N. & Serre, T. Reading the mind\u2019s eye: decoding category information during mental imagery. Neuroimage 50, 818\u2013825 (2010).","journal-title":"Neuroimage"},{"key":"BFsrep37599_CR31","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1006\/nimg.2001.0978","volume":"15","author":"N Tzourio-Mazoyer","year":"2002","unstructured":"Tzourio-Mazoyer, N. et al. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage 15, 273\u2013289 (2002).","journal-title":"Neuroimage"},{"key":"BFsrep37599_CR32","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1038\/nature12112","volume":"497","author":"BE Pfeiffer","year":"2013","unstructured":"Pfeiffer, B. E. & Foster, D. J. Hippocampal place-cell sequences depict future paths to remembered goals. Nature 497, 74\u201379 (2013).","journal-title":"Nature"}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/srep37599.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/srep37599","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/srep37599.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T02:17:43Z","timestamp":1672885063000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/srep37599"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,22]]},"references-count":32,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2016,12,23]]}},"alternative-id":["BFsrep37599"],"URL":"https:\/\/doi.org\/10.1038\/srep37599","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,22]]},"assertion":[{"value":"27 April 2016","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 October 2016","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 November 2016","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing financial interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"37599"}}