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Since there is no specific treatment for yellow fever, there is a necessity to develop an effective agent. The series of acridinone analogues 3 to 5 were synthesized with help of non-conventional microwave heating and confirmed by respective spectral characterization. 5c and 3b showed highest activity to kill 90% of larvae against <jats:italic>A. aegypti<\/jats:italic> and <jats:italic>C. quinquefasciatus<\/jats:italic>, respectively. Also the active products were treated to check the mortality of non-target aquatic species. Through the reports of the larvicidal bioassay, compounds 3b against <jats:italic>C. quinquefasciatus<\/jats:italic> whereas 5c against <jats:italic>A. aegypti<\/jats:italic> were found to be more active. By keeping this as a platform, further extension of the work can be done to find out a valuable drug for controlling disease vectors.<\/jats:p>","DOI":"10.1038\/srep39753","type":"journal-article","created":{"date-parts":[[2017,1,6]],"date-time":"2017-01-06T10:18:15Z","timestamp":1483697895000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Synthesis and insecticidal activity of acridone derivatives to Aedes aegypti and Culex quinquefasciatus larvae and non-target aquatic species"],"prefix":"10.1038","volume":"7","author":[{"given":"Selvaraj Mohana","family":"Roopan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annadurai","family":"Bharathi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naif Abdullah","family":"Al-Dhabi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariadhas Valan","family":"Arasu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Madhumitha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,1,6]]},"reference":[{"key":"BFsrep39753_CR1","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.cppeds.2009.01.001","volume":"39","author":"MA Tolle","year":"2009","unstructured":"Tolle, M. 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