{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T12:46:10Z","timestamp":1791549970055,"version":"4.3.4"},"reference-count":56,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,1,5]],"date-time":"2017-01-05T00:00:00Z","timestamp":1483574400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2017,1,5]],"date-time":"2017-01-05T00:00:00Z","timestamp":1483574400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Although pressure therapy (PT) represents the standard care for prevention and treatment of hypertrophic scar (HS) from burns, its practice is largely based on empirical evidence and its effectiveness remains controversial. To clarify the effect of PT (15\u201325\u2009mmHg) for HS, we performed the systematic review and meta-analysis. Several electronic databases were screened to identify related randomized controlled trials (RCTs). 12 RCTs involving 710 patients with 761 HS resulting from burn injuries were included. Compared with non\/low-PT, cases treated with PT (15\u201325\u2009mmHg) showed significant differences in Vancouver Scar Scale score (MD\u2009=\u2009\u22120.58, 95% CI\u2009=\u2009\u22120.78\u2013\u22120.37), thickness (SMD\u2009=\u2009\u22120.25, 95% CI\u2009=\u2009\u22120.40\u2013\u22120.11), brightness (MD\u2009=\u20092.00, 95% CI\u2009=\u20090.59\u20133.42), redness (MD\u2009=\u2009\u22120.79, 95% CI\u2009=\u2009\u22121.52\u2013\u22120.07), pigmentation (MD\u2009=\u2009\u22120.16, 95% CI\u2009=\u2009\u22120.32\u2013\u22120.00) and hardness (SMD\u2009=\u2009\u22120.65, 95% CI\u2009=\u2009\u22121.07\u2013\u22120.23). However, there was no difference in vascularity (MD\u2009=\u20090.03, 95% CI\u2009=\u2009\u22120.43\u20130.48). Our analysis indicated that patients with HS who were managed with PT (15\u201325\u2009mmHg) showed significant improvements. Due to limitations, more large and well-designed studies are needed to confirm our findings and the side-effects of the PT may also need to be evaluated.<\/jats:p>","DOI":"10.1038\/srep40185","type":"journal-article","created":{"date-parts":[[2017,1,5]],"date-time":"2017-01-05T05:10:38Z","timestamp":1483593038000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":95,"title":["The effectiveness of pressure therapy (15\u201325\u2009mmHg) for hypertrophic burn scars: A systematic review and meta-analysis"],"prefix":"10.1038","volume":"7","author":[{"given":"Jin-Wei","family":"Ai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiang-tao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng-Duo","family":"Pei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"De-Sheng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-ming","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Pei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,1,5]]},"reference":[{"key":"BFsrep40185_CR1","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1007\/s00403-015-1572-0","volume":"307","author":"GP Sidgwick","year":"2015","unstructured":"Sidgwick, G. P., McGeorge, D. & Bayat, A. A comprehensive evidence-based review on the role of topicals and dressings in the management of skin scarring. Arch Dermatol Res 307, 461\u2013477 (2015).","journal-title":"Arch Dermatol Res"},{"key":"BFsrep40185_CR2","first-page":"e29","volume":"15","author":"A Alkhalil","year":"2015","unstructured":"Alkhalil, A. et al. A translational animal model for scar compression therapy using an automated pressure delivery system. Eplasty 15, e29 (2015).","journal-title":"Eplasty"},{"key":"BFsrep40185_CR3","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1097\/PRS.0b013e31821e7006","volume":"128","author":"TH Park","year":"2011","unstructured":"Park, T. H., Seo, S. W., Kim, J. K. & Chang, C. H. Outcomes of surgical excision with pressure therapy using magnets and identification of risk factors for recurrent keloids. Plast Reconstr Surg 128, 431\u2013439 (2011).","journal-title":"Plast Reconstr Surg"},{"key":"BFsrep40185_CR4","doi-asserted-by":"publisher","first-page":"751","DOI":"10.3346\/jkms.2014.29.6.751","volume":"29","author":"D Son","year":"2014","unstructured":"Son, D. & Harijan, A. Overview of Surgical Scar Prevention and Management. J Korean Med Sci 29, 751\u2013757 (2014).","journal-title":"J Korean Med Sci"},{"key":"BFsrep40185_CR5","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1097\/01.ASW.0000408465.81257.46","volume":"24","author":"AD Widgerow","year":"2011","unstructured":"Widgerow, A. D. & Chait, L. A. Scar management practice and science: a comprehensive approach to controlling scar tissue and avoiding hypertrophic scarring. Adv Skin Wound Care 24, 555\u2013561 (2011).","journal-title":"Adv Skin Wound Care"},{"key":"BFsrep40185_CR6","doi-asserted-by":"crossref","first-page":"S108","DOI":"10.1097\/SAP.0000000000000256","volume":"73","author":"C Song","year":"2014","unstructured":"Song, C. Hypertrophic scars and keloids in surgery current concepts. Annals Plastic Surg 73, S108\u2013S118 (2014).","journal-title":"Annals Plastic Surg"},{"key":"BFsrep40185_CR7","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.burns.2004.08.007","volume":"31","author":"L Macintyre","year":"2005","unstructured":"Macintyre, L. & Baird, M. Pressure garments for use in the treatment of hypertrophic scars\u2013an evaluation of current construction techniques in NHS hospitals. Burns 31, 11\u201314 (2005).","journal-title":"Burns"},{"key":"BFsrep40185_CR8","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1097\/BCR.0b013e3181ac01a3","volume":"30","author":"D Harte","year":"2009","unstructured":"Harte, D., Gordon, J., Shaw, M., Stinson, M. & Porter-Armstrong, A. The use of pressure and silicone in hypertrophic scar management in burns patients: A pilot randomized controlled trial. J Burn Care Res 30, 632\u2013642 (2009).","journal-title":"J Burn Care Res"},{"key":"BFsrep40185_CR9","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.1097\/PRS.0b013e3182a8070c","volume":"132","author":"S Kim","year":"2013","unstructured":"Kim, S. et al. Update on scar management guidelines for treating Asian patients. Plast Reconstr Surg 132, 1580\u20131589 (2013).","journal-title":"Plast Reconstr Surg"},{"key":"BFsrep40185_CR10","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1590\/0100-69912015001003","volume":"42","author":"SM Carvalhaes","year":"2015","unstructured":"Carvalhaes, S. M., Petroianu, A., Ferreira, M. A. T., Barros, V. M. D. & Lopes, R. V. Assesment of the treatment of earlobe keloids with triamcinolone injections, surgical resection, and local pressure. Rev Col Bras Cir 42, 9\u201313 (2015).","journal-title":"Rev Col Bras Cir"},{"key":"BFsrep40185_CR11","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1111\/exd.12506","volume":"23","author":"FN Williams","year":"2014","unstructured":"Williams, F. N., Herndon, D. N. & Branski, L. K. Where we stand with human hypertrophic and keloid scar models. Exp Dermatol 23, 811\u2013812 (2014).","journal-title":"Exp Dermatol"},{"key":"BFsrep40185_CR12","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.burns.2004.06.018","volume":"32","author":"L Macintyre","year":"2006","unstructured":"Macintyre, L. & Baird, M. Pressure garments for use in the treatment of hypertrophic scars\u2014a review of the problems associated with their use. Burns 32, 10\u201315 (2006).","journal-title":"Burns"},{"key":"BFsrep40185_CR13","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1046\/j.1524-475X.2003.11504.x","volume":"11","author":"F Reno","year":"2003","unstructured":"Reno, F. et al. In vitro mechanical compression induces apoptosis and regulates cytokines release in hypertrophic scars. Wound Repair Regen 11, 331\u2013336 (2003).","journal-title":"Wound Repair Regen"},{"key":"BFsrep40185_CR14","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1097\/PRS.0000000000001507","volume":"136","author":"JY Kim","year":"2015","unstructured":"Kim, J. Y. et al. Burn scar biomechanics after pressure garment therapy. Plast Reconstr Surg 136, 572\u2013581 (2015).","journal-title":"Plast Reconstr Surg"},{"key":"BFsrep40185_CR15","first-page":"205","volume":"26","author":"BS Atiyeh","year":"2013","unstructured":"Atiyeh, B. S., El, K. A. M. & Dibo, S. A. Pressure garment therapy (PGT) of burn scars: evidence-based efficacy. Ann Burns Fire Disasters 26, 205\u2013212 (2013).","journal-title":"Ann Burns Fire Disasters"},{"key":"BFsrep40185_CR16","doi-asserted-by":"crossref","first-page":"3321","DOI":"10.3760\/cma.j.issn.0366-6999.20130833","volume":"126","author":"D Huang","year":"2013","unstructured":"Huang, D., Shen, K. H. & Wang, H. G. Pressure therapy upregulates matrix metalloproteinase expression and downregulates collagen expression in hypertrophic scar tissue. Chin Med J (Engl) 126, 3321\u20133324 (2013).","journal-title":"Chin Med J (Engl)"},{"key":"BFsrep40185_CR17","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1684\/ejd.2014.2356","volume":"24","author":"S Meaume","year":"2014","unstructured":"Meaume, S., Le Pillouer-Prost, A., Richert, B., Roseeuw, D. & Vadoud, J. Management of scars: updated practical guidelines and use of silicones. Eur J Dermatol 24, 435\u2013443 (2014).","journal-title":"Eur J Dermatol"},{"key":"BFsrep40185_CR18","doi-asserted-by":"publisher","first-page":"306e","DOI":"10.1097\/PRS.0b013e3182268c69","volume":"128","author":"L Steinstraesser","year":"2011","unstructured":"Steinstraesser, L. et al. Pressure garment therapy alone and in combination with silicone for the prevention of hypertrophic scarring: randomized controlled trial with intraindividual comparison. Plast Reconstr Surg 128, 306e\u2013313e (2011).","journal-title":"Plast Reconstr Surg"},{"key":"BFsrep40185_CR19","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1111\/j.1365-2230.2007.02620.x","volume":"33","author":"C Chrisostomidis","year":"2008","unstructured":"Chrisostomidis, C. et al. Management of external ear keloids using form-pressure therapy. Clin Exp Dermatol 33, 273\u2013275 (2008).","journal-title":"Clin Exp Dermatol"},{"key":"BFsrep40185_CR20","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1097\/BCR.0B013E318053D35B","volume":"28","author":"PA Sharp","year":"2007","unstructured":"Sharp, P. A., Dougherty, M. E. & Kagan, R. J. The Effect of Positioning Devices and Pressure Therapy on Outcome After Full-Thickness Burns of the Neck. J Burn Care Res 28, 451\u2013459 (2007).","journal-title":"J Burn Care Res"},{"key":"BFsrep40185_CR21","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.bjps.2007.10.052","volume":"62","author":"A Anzarut","year":"2009","unstructured":"Anzarut, A., Olson, J., Singh, P., Rowe, B. H. & Tredget, E. E. The effectiveness of pressure garment therapy for the prevention of abnormal scarring after burn injury: a meta-analysis. J Plast Reconstr Aesthet Surg 62, 77\u201384 (2009).","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"BFsrep40185_CR22","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.1016\/j.burns.2014.02.011","volume":"40","author":"AI Arno","year":"2014","unstructured":"Arno, A. I., Gauglitz, G. G., Barret, J. P. & Jeschke, M. G. Up-to-date approach to manage keloids and hypertrophic scars: A useful guide. Burns 40, 1255\u20131266 (2014).","journal-title":"Burns"},{"key":"BFsrep40185_CR23","first-page":"812","volume":"40","author":"MH Gold","year":"2014","unstructured":"Gold, M. H. et al. Updated international clinical recommendations on scar management: Part 1 \u2014 evaluating the evidence. Dermatol Surg 40, 812\u2013824 (2014).","journal-title":"Dermatol Surg"},{"key":"BFsrep40185_CR24","first-page":"825","volume":"40","author":"MH Gold","year":"2014","unstructured":"Gold, M. H. et al. Updated international clinical recommendations on scar management: part 2 \u2014 algorithms for scar prevention and treatment. Dermatol Surg 40, 825\u2013831 (2014).","journal-title":"Dermatol Surg"},{"key":"BFsrep40185_CR25","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1093\/ptj\/89.9.873","volume":"89","author":"D Moher","year":"2009","unstructured":"Moher, D., Liberati, A., Tetzlaff, J. & Libeti, T. Reprint\u2013preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Phys Ther 89, 873\u2013880 (2009).","journal-title":"Phys Ther"},{"key":"BFsrep40185_CR26","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1111\/jebm.12141","volume":"8","author":"X Zeng","year":"2015","unstructured":"Zeng, X. et al. The methodological quality assessment tools for preclinical and clinical studies, systematic review and meta-analysis, and clinical practice guideline: a systematic review. J Evid Based Med 8, 2\u201310 (2015).","journal-title":"J Evid Based Med"},{"key":"BFsrep40185_CR27","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1016\/j.burns.2010.04.014","volume":"36","author":"LH Engrav","year":"2010","unstructured":"Engrav, L. H. et al. 12-Year within-wound study of the effectiveness of custom pressure garment therapy. Burns 36, 975\u2013983 (2010).","journal-title":"Burns"},{"key":"BFsrep40185_CR28","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1097\/BCR.0b013e3181db52a7","volume":"31","author":"CWP Li-Tsang","year":"2010","unstructured":"Li-Tsang, C. W. P., Zheng, Y. P. & Lau, J. C. M. A randomized clinical trial to study the effect of silicone gel dressing and pressure therapy on posttraumatic hypertrophic scars. J Burn Care Res 31, 448\u2013457 (2010).","journal-title":"J Burn Care Res"},{"key":"BFsrep40185_CR29","doi-asserted-by":"publisher","first-page":"1234","DOI":"10.1016\/j.burns.2010.05.008","volume":"36","author":"LH Candy","year":"2010","unstructured":"Candy, L. H., Cecilia, L. T. & Ping, Z. Y. Effect of different pressure magnitudes on hypertrophic scar in a Chinese population. Burns 36, 1234\u20131241 (2010).","journal-title":"Burns"},{"key":"BFsrep40185_CR30","doi-asserted-by":"publisher","first-page":"S177","DOI":"10.1097\/00004630-200001001-00086","volume":"21","author":"ML Moore","year":"2000","unstructured":"Moore, M. L. et al. Effectiveness of custom pressure garments in wound management a prospective trial within wounds with verified pressure. J Burn Care Res 21, S177 (2000).","journal-title":"J Burn Care Res"},{"key":"BFsrep40185_CR31","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1097\/00004630-199509000-00002","volume":"16","author":"P Chang","year":"1995","unstructured":"Chang, P. et al. Prospective, randomized study of the efficacy of pressure garment therapy in patients with burns. J Burn Care Rehabil 16, 473\u2013475 (1995).","journal-title":"J Burn Care Rehabil"},{"key":"BFsrep40185_CR32","doi-asserted-by":"publisher","first-page":"696","DOI":"10.1016\/j.burns.2005.04.014","volume":"31","author":"E Van den Kerckhove","year":"2005","unstructured":"Van den Kerckhove, E. et al. The assessment of erythema and thickness on burn related scars during pressure garment therapy as a preventive measure for hypertrophic scarring. Burns 31, 696\u2013702 (2005).","journal-title":"Burns"},{"key":"BFsrep40185_CR33","doi-asserted-by":"crossref","unstructured":"Groce, A., Herndon, D. N., McCauley, R. L. & Chinkes, D. The effect of high versus low pressure garments in the control of hypertrophic scars in the burned child: a preliminary 6 month report. Proceedings of the American Burn Association (2000).","DOI":"10.1097\/00004630-200001001-00085"},{"key":"BFsrep40185_CR34","doi-asserted-by":"crossref","unstructured":"Groce, A., Herndon, D. N., McCauley, R. L. & Chinkes, D. The effects of pressure versus no pressure garments in the control of hypertrophic scarring in children with small burns: a preliminary 6 month report. Proceedings of the American Burn Association (2000).","DOI":"10.1097\/00004630-200001001-00088"},{"key":"BFsrep40185_CR35","first-page":"7583","volume":"13","author":"J Li","year":"2009","unstructured":"Li, J., Bai, Y. Q., L\u00fc, G. L., Du, Y. R. & Zhao, N. Influence of different pressure tension bandage on inhibiting scar proliferation(in Chinese). Zhongguo Zuzhi Gongcheng Yanjiu 13, 7583\u20137586 (2009).","journal-title":"Zhongguo Zuzhi Gongcheng Yanjiu"},{"key":"BFsrep40185_CR36","first-page":"462","volume":"26","author":"HP Li","year":"2004","unstructured":"Li, H. P. et al. The short term effect of pressure therapy and silicone gel on controlling the hypertrophic scar(in Chinese). Zhonghua Wuli Yixue Yu Kangfu Zazhi 26, 462\u2013465 (2004).","journal-title":"Zhonghua Wuli Yixue Yu Kangfu Zazhi"},{"key":"BFsrep40185_CR37","first-page":"1310","volume":"19","author":"P Liu","year":"2012","unstructured":"Liu, P. et al. Sificon gel dressings and pressure therapy for treatment of hypertrophic burn scar in limbs(in Chinese). Linchuang Yixue Gongcheng 19, 1310\u20131311 (2012).","journal-title":"Linchuang Yixue Gongcheng"},{"key":"BFsrep40185_CR38","first-page":"475","volume":"22","author":"LW Xu","year":"2005","unstructured":"Xu, L. W., Cai, S. P., Zou, Y. X., Wang, Y. Q. & Pang, S. Q. Heparin sodium cream combined with pressure therapy to treat deep collapsed after 2 degree burn scar hyperplasia in 87 cases(in Chinese). Zhonghua Shaoshang Zazhi 22, 475 (2005).","journal-title":"Zhonghua Shaoshang Zazhi"},{"key":"BFsrep40185_CR39","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1016\/j.burns.2008.07.016","volume":"35","author":"MC Bloemen","year":"2009","unstructured":"Bloemen, M. C. et al. Prevention and curative management of hypertrophic scar formation. Burns 35, 463\u2013475 (2009).","journal-title":"Burns"},{"key":"BFsrep40185_CR40","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.1097\/SCS.0b013e318175f4df","volume":"19","author":"P Davoodi","year":"2008","unstructured":"Davoodi, P. & Fernandez JM, O. S. J. Postburn sequelae in the pediatric patient: clinical presentations and treatment options. J Craniofac Surg 19, 1047\u20131052 (2008).","journal-title":"J Craniofac Surg"},{"key":"BFsrep40185_CR41","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1097\/SCS.0b013e318175f3a7","volume":"19","author":"B Berman","year":"2008","unstructured":"Berman, B., Viera, M. H., Amini, S., Huo, R. & Jones, I. S. Prevention and management of hypertrophic scars and keloids after burns in children. J Craniofac Surg 19, 989\u20131006 (2008).","journal-title":"J Craniofac Surg"},{"key":"BFsrep40185_CR42","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.burns.2007.07.003","volume":"34","author":"K Rappoport","year":"2008","unstructured":"Rappoport, K., M\u00fcller, R. & Flores-Mir, C. Dental and skeletal changes during pressure garment use in facial burns: A systematic review. Burns 34, 18\u201323 (2008).","journal-title":"Burns"},{"key":"BFsrep40185_CR43","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1016\/j.burns.2009.01.011","volume":"35","author":"S Ripper","year":"2009","unstructured":"Ripper, S., Renneberg, B., Landmann, C., Weigel, G. & Germann, G. Adherence to pressure garment therapy in adult burn patients. Burns 35, 657\u2013664 (2009).","journal-title":"Burns"},{"key":"BFsrep40185_CR44","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1016\/j.bjps.2014.04.011","volume":"67","author":"S Monstrey","year":"2014","unstructured":"Monstrey, S. et al. Updated scar management practical guidelines: non-invasive and invasive measures. J Plast Reconstr Aesthet Surg 67, 1017\u20131025 (2014).","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"BFsrep40185_CR45","doi-asserted-by":"publisher","first-page":"113","DOI":"10.2119\/molmed.2009.00153","volume":"17","author":"GG Gauglitz","year":"2011","unstructured":"Gauglitz, G. G., Korting, H. C., Pavicic, T., Ruzicka, T. & Jeschke, M. G. Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies. Mol Med 17, 113\u2013125 (2011).","journal-title":"Mol Med"},{"key":"BFsrep40185_CR46","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1080\/1363849021000007079","volume":"5","author":"BA Latenser","year":"2002","unstructured":"Latenser, B. A. & Kowal-Vern, A. Paediatric burn rehabilitation. Pediatr Rehabil 5, 3\u201310 (2002).","journal-title":"Pediatr Rehabil"},{"key":"BFsrep40185_CR47","doi-asserted-by":"publisher","first-page":"1205","DOI":"10.1034\/j.1399-3003.2000.16f29.x","volume":"16","author":"M Hubbard","year":"2000","unstructured":"Hubbard, M., Masters, I. B., Williams, G. R. & Chang, A. B. Severe obstructive sleep apnoea secondary to pressure garments used in the treatment of hypertrophic burn scars. Eur Respir J 16, 1205\u20131207 (2000).","journal-title":"Eur Respir J"},{"key":"BFsrep40185_CR48","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1016\/S0305-4179(98)00026-6","volume":"24","author":"F Williams","year":"1998","unstructured":"Williams, F., Knapp, D. & Wallen, M. Comparison of the characteristics and features of pressure used in the management of burn scars. Burns 24, 322\u2013335 (1998).","journal-title":"Burns"},{"key":"BFsrep40185_CR49","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1097\/00004630-199403000-00015","volume":"15","author":"J Johnson","year":"1994","unstructured":"Johnson, J., Greenspan, B., Gorga, D., Nagler, W. & Goodwin, C. Conservative treatment using compression suits for second and third degree burns in children. J Burn Care Rehabil 15, 180\u2013188 (1994).","journal-title":"J Burn Care Rehabil"},{"key":"BFsrep40185_CR50","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1097\/00006534-199802000-00021","volume":"10","author":"H Giele","year":"1998","unstructured":"Giele, H., Liddiard, K., Booth, K. & Wood, F. Anatomical variations in pressures generated by pressure garments. Plast Reconstr Surg 10, 399\u2013406 (1998).","journal-title":"Plast Reconstr Surg"},{"key":"BFsrep40185_CR51","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1097\/00004630-199703000-00013","volume":"18","author":"M Staley","year":"1997","unstructured":"Staley, M., Richard, R., Billmire, D. & Warden, G. Head\/face\/neck burns: therapist considerations for the pediatric patient. J Burn Care Rehabil 18, 164\u2013171 (1997).","journal-title":"J Burn Care Rehabil"},{"key":"BFsrep40185_CR52","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1097\/00004630-199105000-00011","volume":"12","author":"RS Ward","year":"1991","unstructured":"Ward, R. S. Pressure therapy for the control of hypertrophic scar formation after burn injury. A history and review. J Burn Care Rehabil 12, 257\u2013262 (1991).","journal-title":"J Burn Care Rehabil"},{"key":"BFsrep40185_CR53","doi-asserted-by":"publisher","first-page":"598","DOI":"10.5014\/ajot.54.6.598","volume":"54","author":"R Stewart","year":"2000","unstructured":"Stewart, R., Bhagwanjee, A. M., Mbakaza, Y. & Binase, T. Pressure garment adherence in adult patients with burn injuries: an analysis of patient and clinician perceptions. Am J Occup Ther 54, 598\u2013606 (2000).","journal-title":"Am J Occup Ther"},{"key":"BFsrep40185_CR54","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1097\/BCR.0000000000000253","volume":"37","author":"PA Sharp","year":"2016","unstructured":"Sharp, P. A., Pan, B., Yakuboff, K. P. & Rothchild, D. Development of a Best Evidence Statement for the Use of Pressure Therapy for Management of Hypertrophic Scarring. J Burn Care Res 37, 255\u2013264 (2016).","journal-title":"J Burn Care Res"},{"key":"BFsrep40185_CR55","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.burns.2004.06.018","volume":"32","author":"L Macintyre","year":"2006","unstructured":"Macintyre, L. & Baird, M. Pressure garments for use in the treatment of hypertrophic scars-a review of the problems associated with their use. Burns 32, 10\u201315 (2006).","journal-title":"Burns"},{"key":"BFsrep40185_CR56","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1097\/00004630-199905000-00016","volume":"20","author":"NB Fricke","year":"1999","unstructured":"Fricke, N. B., Omnell, M. L., Dutcher, K. A., Hollender, L. G. & Engrav, L. H. Skeletal and dental disturbances in children after facial burns and pressure garment use: a 4-year follow-up. J Burn Care Rehabil 20, 239\u2013249 (1999).","journal-title":"J Burn Care Rehabil"}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/srep40185.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/srep40185","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/srep40185.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T11:36:24Z","timestamp":1718969784000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/srep40185"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,5]]},"references-count":56,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2017,3,15]]}},"alternative-id":["BFsrep40185"],"URL":"https:\/\/doi.org\/10.1038\/srep40185","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,5]]},"assertion":[{"value":"23 August 2016","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 December 2016","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 January 2017","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing financial interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"40185"}}