{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T13:56:23Z","timestamp":1788530183839,"version":"build-2803163510"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,1,9]],"date-time":"2017-01-09T00:00:00Z","timestamp":1483920000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2017,1,9]],"date-time":"2017-01-09T00:00:00Z","timestamp":1483920000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Antepartum hemorrhage (APH) is an important cause of perinatal mortality and maternal morbidity in pregnant women with placenta previa in the world. However, the epidemiological characteristics are not completely understood. We performed an initial systematic review and meta-analysis to assess the prevalence of APH in pregnant women with placenta previa. It was totally performed following the Preferred Reporting Items for Systematic reviews and Meta-Analysis statement. PubMed, Elsevier Science Direct, and the Cochrane Library were searched before April 2016. A meta-analysis with a random-effects model based on a proportions approach was performed to determine the prevalence. Stratified analyses, meta-regression method, and sensitivity analysis were utilized to analyze the heterogeneity. A total of 29 articles were included. The pooled overall prevalence of APH among pregnant women with placenta previa was 51.6% (95% CI 42.7\u201360.6) in a heterogeneous set of studies (<jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u200997.9). Correlation analysis found that there was a positive correlation between prevalence and percentage of multiparous (r\u2009=\u20090.534, P\u2009=\u20090.027) and a negative correlation between prevalence and survey year (r\u2009=\u2009\u22120.400, P\u2009=\u20090.031). In conclusion, the prevalence of APH was a high condition among pregnant women with placenta previa.<\/jats:p>","DOI":"10.1038\/srep40320","type":"journal-article","created":{"date-parts":[[2017,1,9]],"date-time":"2017-01-09T10:16:19Z","timestamp":1483956979000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":56,"title":["Prevalence of antepartum hemorrhage in women with placenta previa: a systematic review and meta-analysis"],"prefix":"10.1038","volume":"7","author":[{"given":"Dazhi","family":"Fan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoling","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengping","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,1,9]]},"reference":[{"key":"BFsrep40320_CR1","first-page":"12","volume":"4","author":"R Giordano","year":"2010","unstructured":"Giordano, R. et al. Antepartum haemorrhage. J Prenat Med. 4, 12\u20136 (2010).","journal-title":"J Prenat Med"},{"key":"BFsrep40320_CR2","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1080\/01443610802091487","volume":"28","author":"P Sinha","year":"2008","unstructured":"Sinha, P. & Kuruba, N. Ante-partum haemorrhage: an update. J Obstet Gynaecol. 28, 377\u201381 (2008).","journal-title":"J Obstet Gynaecol"},{"key":"BFsrep40320_CR3","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1080\/j.1600-0412.1999.780303.x","volume":"78","author":"CC Chan","year":"1999","unstructured":"Chan, C. C. & To, W. W. Antepartum hemorrhage of unknown origin\u2013what is its clinical significance? Acta Obstet Gynecol Scand. 78, 186\u201390 (1999).","journal-title":"Acta Obstet Gynecol Scand"},{"key":"BFsrep40320_CR4","doi-asserted-by":"crossref","unstructured":"Silver, R. M. Abnormal Placentation: Placenta Previa, Vasa Previa, and Placenta Accreta. Obstet Gynecol. (2015).","DOI":"10.1097\/AOG.0000000000001005"},{"key":"BFsrep40320_CR5","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1055\/s-2000-9269","volume":"17","author":"JM Crane","year":"2000","unstructured":"Crane, J. M. et al. Maternal complications with placenta previa. Am J Perinatol. 17, 101\u20135 (2000).","journal-title":"Am J Perinatol"},{"key":"BFsrep40320_CR6","doi-asserted-by":"publisher","first-page":"669.e1","DOI":"10.1016\/j.ajog.2015.01.004","volume":"212","author":"KL Downes","year":"2015","unstructured":"Downes, K. L. et al. Previous prelabor or intrapartum cesarean delivery and risk of placenta previa. Am J Obstet Gynecol. 212, 669.e1\u20136 (2015).","journal-title":"Am J Obstet Gynecol"},{"key":"BFsrep40320_CR7","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1111\/tmi.12100","volume":"18","author":"JA Cresswell","year":"2013","unstructured":"Cresswell, J. A. et al. Prevalence of placenta praevia by world region: a systematic review and meta-analysis. Trop Med Int Health. 18, 712\u201324 (2013).","journal-title":"Trop Med Int Health"},{"key":"BFsrep40320_CR8","doi-asserted-by":"crossref","unstructured":"Miller, E. S. et al. Does the presence of placental basal plate myometrial fibres increase the risk of subsequent morbidly adherent placenta: a case-control study. BJOG. (2015).","DOI":"10.1111\/1471-0528.13579"},{"key":"BFsrep40320_CR9","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1097\/01.AOG.0000206182.63788.80","volume":"107","author":"D Getahun","year":"2006","unstructured":"Getahun, D. et al. Previous cesarean delivery and risks of placenta previa and placental abruption. Obstet Gynecol. 107, 771\u20138 (2006).","journal-title":"Obstet Gynecol."},{"key":"BFsrep40320_CR10","doi-asserted-by":"publisher","first-page":"266 e1","DOI":"10.1016\/j.ajog.2009.06.009","volume":"201","author":"P Vergani","year":"2009","unstructured":"Vergani, P. et al. Placenta previa: distance to internal os and mode of delivery. Am J Obstet Gynecol. 201, 266 e1\u20135 (2009).","journal-title":"Am J Obstet Gynecol"},{"key":"BFsrep40320_CR11","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.ijgo.2006.02.006","volume":"93","author":"L Tuzovic","year":"2006","unstructured":"Tuzovic, L. Complete versus incomplete placenta previa and obstetric outcome. Int J Gynaecol Obstet. 93, 110\u20137 (2006).","journal-title":"Int J Gynaecol Obstet"},{"key":"BFsrep40320_CR12","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.ejogrb.2015.10.015","volume":"195","author":"A Pivano","year":"2015","unstructured":"Pivano, A. et al. A score to predict the risk of emergency caesarean delivery in women with antepartum bleeding and placenta praevia. Eur J Obstet Gynecol Reprod Biol. 195, 173\u2013176 (2015).","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"BFsrep40320_CR13","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1038\/jp.2013.185","volume":"34","author":"BC Young","year":"2014","unstructured":"Young, B. C. et al. Does previa location matter? Surgical morbidity associated with location of a placenta previa. J Perinatol. 34, 264\u20137 (2014).","journal-title":"J Perinatol."},{"key":"BFsrep40320_CR14","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1016\/j.ijgo.2011.03.012","volume":"114","author":"G Daskalakis","year":"2011","unstructured":"Daskalakis, G. et al. Impact of placenta previa on obstetric outcome. Int J Gynaecol Obstet. 114, 238\u201341 (2011).","journal-title":"Int J Gynaecol Obstet"},{"key":"BFsrep40320_CR15","first-page":"728","volume":"25","author":"SM Bhat","year":"2004","unstructured":"Bhat, S. M. et al. Placenta previa in a referral hospital in Oman. Saudi Med J. 25, 728\u201331 (2004).","journal-title":"Saudi Med J"},{"key":"BFsrep40320_CR16","doi-asserted-by":"publisher","first-page":"e0149036","DOI":"10.1371\/journal.pone.0149036","volume":"11","author":"JE Shin","year":"2016","unstructured":"Shin, J. E. et al. Serial Change in Cervical Length for the Prediction of Emergency Cesarean Section in Placenta Previa. PLoS One. 11, e0149036 (2016).","journal-title":"PLoS One."},{"key":"BFsrep40320_CR17","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.ejogrb.2016.03.012","volume":"201","author":"M Goto","year":"2016","unstructured":"Goto, M. et al. Placenta previa with early opening of the uterine isthmus is associated with high risk of bleeding during pregnancy, and massive haemorrhage during caesarean delivery. Eur J Obstet Gynecol Reprod Biol. 201, 7\u201311 (2016).","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"BFsrep40320_CR18","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1111\/j.1447-0756.2011.01669.x","volume":"38","author":"K Fukushima","year":"2012","unstructured":"Fukushima, K. et al. Cervical length predicts placental adherence and massive hemorrhage in placenta previa. J Obstet Gynaecol Res. 38, 192\u20137 (2012).","journal-title":"J Obstet Gynaecol Res"},{"key":"BFsrep40320_CR19","first-page":"272","volume":"94","author":"W Suknikhom","year":"2011","unstructured":"Suknikhom, W. & Tannirandorn, Y. Previous uterine operation and placenta previa. J Med Assoc Thai. 94, 272\u20137 (2011).","journal-title":"J Med Assoc Thai"},{"key":"BFsrep40320_CR20","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1111\/j.1447-0756.2010.01446.x","volume":"37","author":"T Mimura","year":"2011","unstructured":"Mimura, T. et al. Correlation between the cervical length and the amount of bleeding during cesarean section in placenta previa. J Obstet Gynaecol Res. 37, 830\u20135 (2011).","journal-title":"J Obstet Gynaecol Res"},{"key":"BFsrep40320_CR21","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1002\/jcu.20849","volume":"39","author":"J Hasegawa","year":"2011","unstructured":"Hasegawa, J. et al. Can ultrasonography of the placenta previa predict antenatal bleeding? J Clin Ultrasound. 39, 458\u201362 (2011).","journal-title":"J Clin Ultrasound"},{"key":"BFsrep40320_CR22","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/S1701-2163(16)34096-8","volume":"31","author":"A Bahar","year":"2009","unstructured":"Bahar, A. et al. Risk factors and pregnancy outcome in different types of placenta previa. J Obstet Gynaecol Can. 31, 126\u201331 (2009).","journal-title":"J Obstet Gynaecol Can"},{"key":"BFsrep40320_CR23","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1272\/jnms.75.146","volume":"75","author":"A Oya","year":"2008","unstructured":"Oya, A. et al. Risk factors for peripartum blood transfusion in women with placenta previa: a retrospective analysis. J Nippon Med Sch. 75, 146\u201351 (2008).","journal-title":"J Nippon Med Sch"},{"key":"BFsrep40320_CR24","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1515\/JPM.2008.089","volume":"36","author":"S Matsubara","year":"2008","unstructured":"Matsubara, S. et al. Blood loss in low-lying placenta: placental edge to cervical internal os distance of less vs. more than 2 cm. J Perinat Med. 36, 507\u201312 (2008).","journal-title":"J Perinat Med"},{"key":"BFsrep40320_CR25","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1046\/j.1469-0705.2001.00420.x","volume":"18","author":"S Ghourab","year":"2001","unstructured":"Ghourab, S. Third-trimester transvaginal ultrasonography in placenta previa: does the shape of the lower placental edge predict clinical outcome? Ultrasound Obstet Gynecol. 18, 103\u20138 (2001).","journal-title":"Ultrasound Obstet Gynecol"},{"key":"BFsrep40320_CR26","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1080\/01443610063417","volume":"20","author":"CM Lam","year":"2000","unstructured":"Lam, C. M. et al. Women with placenta praevia and antepartum haemorrhage have a worse outcome than those who do not bleed before delivery. J Obstet Gynaecol. 20, 27\u201331 (2000).","journal-title":"J Obstet Gynaecol"},{"key":"BFsrep40320_CR27","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/0028-2243(85)90012-7","volume":"20","author":"IG Gorodeski","year":"1985","unstructured":"Gorodeski, I. G. et al. Placenta previa\u2013the identification of low- and high-risk subgroups. Eur J Obstet Gynecol Reprod Biol. 20, 133\u201343 (1985).","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"BFsrep40320_CR28","doi-asserted-by":"publisher","first-page":"1683","DOI":"10.7150\/ijms.6416","volume":"10","author":"A Sekiguchi","year":"2013","unstructured":"Sekiguchi, A. et al. Type and location of placenta previa affect preterm delivery risk related to antepartum hemorrhage. Int J Med Sci. 10, 1683\u20138 (2013).","journal-title":"Int J Med Sci."},{"key":"BFsrep40320_CR29","doi-asserted-by":"publisher","first-page":"1367","DOI":"10.3109\/14767058.2015.1051023","volume":"29","author":"AC Wortman","year":"2016","unstructured":"Wortman, A. C. et al. Bleeding complications in pregnancies with low-lying placenta. J Matern Fetal Neonatal Med. 29, 1367\u201371 (2016).","journal-title":"J Matern Fetal Neonatal Med"},{"key":"BFsrep40320_CR30","doi-asserted-by":"publisher","first-page":"563","DOI":"10.3109\/14767058.2012.743524","volume":"26","author":"A Curti","year":"2013","unstructured":"Curti, A. et al. Cervical length and risk of antepartum hemorrhage in presence of low-lying placenta. J Matern Fetal Neonatal Med. 26, 563\u20135 (2013).","journal-title":"J Matern Fetal Neonatal Med"},{"key":"BFsrep40320_CR31","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1515\/JPM.2011.125","volume":"40","author":"SG Fishman","year":"2012","unstructured":"Fishman, S. G. et al. Risk factors for preterm delivery with placenta previa. J Perinat Med. 40, 39\u201342 (2012).","journal-title":"J Perinat Med"},{"key":"BFsrep40320_CR32","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1097\/AOG.0b013e3181ea2deb","volume":"116","author":"IA Stafford","year":"2010","unstructured":"Stafford, I. A. et al. Ultrasonographic cervical length and risk of hemorrhage in pregnancies with placenta previa. Obstet Gynecol. 116, 595\u2013600 (2010).","journal-title":"Obstet Gynecol."},{"key":"BFsrep40320_CR33","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/S0020-7292(03)00211-X","volume":"83","author":"O Ogueh","year":"2003","unstructured":"Ogueh, O. et al. Obstetric implications of low-lying placentas diagnosed in the second trimester. International Journal of Gynecology & Obstetrics. 83, 11\u201317 (2003).","journal-title":"International Journal of Gynecology & Obstetrics"},{"key":"BFsrep40320_CR34","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1055\/s-2003-45282","volume":"20","author":"CP Dola","year":"2003","unstructured":"Dola, C. P. et al. Placenta previa: does its type affect pregnancy outcome? Am J Perinatol. 20, 353\u201360 (2003).","journal-title":"Am J Perinatol"},{"key":"BFsrep40320_CR35","doi-asserted-by":"publisher","first-page":"441","DOI":"10.7863\/jum.1996.15.6.441","volume":"15","author":"WB Dawson","year":"1996","unstructured":"Dawson, W. B. et al. Translabial ultrasonography and placenta previa: does measurement of the os-placenta distance predict outcome? J Ultrasound Med. 15, 441\u20136 (1996).","journal-title":"J Ultrasound Med"},{"key":"BFsrep40320_CR36","doi-asserted-by":"publisher","first-page":"1395","DOI":"10.3109\/14767058.2015.1049152","volume":"29","author":"M Kollmann","year":"2016","unstructured":"Kollmann, M. et al. Placenta praevia: incidence, risk factors and outcome. J Matern Fetal Neonatal Med. 29, 1395\u20138 (2016).","journal-title":"J Matern Fetal Neonatal Med"},{"key":"BFsrep40320_CR37","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1007\/s00404-011-2074-8","volume":"285","author":"E Giambattista","year":"2012","unstructured":"Giambattista, E. et al. Predicting factors for emergency peripartum hysterectomy in women with placenta previa. Arch Gynecol Obstet. 285, 901\u20136 (2012).","journal-title":"Arch Gynecol Obstet"},{"key":"BFsrep40320_CR38","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1002\/uog.6301","volume":"33","author":"T Ghi","year":"2009","unstructured":"Ghi, T. et al. Cervical length and risk of antepartum bleeding in women with complete placenta previa. Ultrasound Obstet Gynecol. 33, 209\u201312 (2009).","journal-title":"Ultrasound Obstet Gynecol"},{"key":"BFsrep40320_CR39","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.ejogrb.2003.10.039","volume":"117","author":"CD Love","year":"2004","unstructured":"Love, C. D. et al. Major placenta praevia should not preclude out-patient management. Eur J Obstet Gynecol Reprod Biol. 117, 24\u20139 (2004).","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"BFsrep40320_CR40","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1007\/s00404-010-1737-1","volume":"284","author":"MM Zaitoun","year":"2011","unstructured":"Zaitoun, M. M. et al. Does cervical length and the lower placental edge thickness measurement correlates with clinical outcome in cases of complete placenta previa? Arch Gynecol Obstet. 284, 867\u201373 (2011).","journal-title":"Arch Gynecol Obstet"},{"key":"BFsrep40320_CR41","doi-asserted-by":"crossref","unstructured":"Mastrolia, S. A. et al. Placenta previa associated with severe bleeding leading to hospitalization and delivery: a retrospective population-based cohort study. J Matern Fetal Neonatal Med. 1\u20135 (2016).","DOI":"10.3109\/14767058.2015.1131264"},{"key":"BFsrep40320_CR42","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1007\/s00404-010-1598-7","volume":"284","author":"T Rosenberg","year":"2011","unstructured":"Rosenberg, T. et al. Critical analysis of risk factors and outcome of placenta previa. Arch Gynecol Obstet. 284, 47\u201351 (2011).","journal-title":"Arch Gynecol Obstet"},{"key":"BFsrep40320_CR43","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1093\/ije\/dyg238","volume":"33","author":"RR Patel","year":"2004","unstructured":"Patel, R. R. et al. Does gestation vary by ethnic group? A London-based study of over 122,000 pregnancies with spontaneous onset of labour. Int J Epidemiol. 33, 107\u201313 (2004).","journal-title":"Int J Epidemiol"},{"key":"BFsrep40320_CR44","doi-asserted-by":"publisher","first-page":"2017","DOI":"10.1001\/jama.2016.0927","volume":"315","author":"G Molina","year":"2016","unstructured":"Molina, G. et al. Maternal and Neonatal Mortality After Cesarean Delivery\u2013Reply. JAMA. 315, 2017 (2016).","journal-title":"JAMA"},{"key":"BFsrep40320_CR45","doi-asserted-by":"publisher","first-page":"2373","DOI":"10.1001\/jama.2015.15845","volume":"314","author":"DA Mata","year":"2015","unstructured":"Mata, D. A. et al. Prevalence of Depression and Depressive Symptoms Among Resident Physicians: A Systematic Review and Meta-analysis. JAMA. 314, 2373\u201383 (2015).","journal-title":"JAMA."},{"key":"BFsrep40320_CR46","doi-asserted-by":"publisher","first-page":"13546","DOI":"10.1038\/srep13546","volume":"5","author":"W Wang","year":"2015","unstructured":"Wang, W. et al. The prevalence of benign prostatic hyperplasia in mainland China: evidence from epidemiological surveys. Sci Rep. 5, 13546 (2015).","journal-title":"Sci Rep"},{"key":"BFsrep40320_CR47","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1016\/S0140-6736(12)60692-8","volume":"380","author":"L Jones","year":"2012","unstructured":"Jones, L. et al. Prevalence and risk of violence against children with disabilities: a systematic review and meta-analysis of observational studies. The Lancet. 380, 899\u2013907 (2012).","journal-title":"The Lancet"},{"key":"BFsrep40320_CR48","unstructured":"Fan, D. et al. Incidence of antepartum hemorrhage in women with placenta previa: a systematic review and meta-analysis. PROSPERO 2016:CRD42016037823 Available fromhttp:\/\/www.crd.york.ac.uk\/PROSPERO\/display_record.asp?ID=CRD42016037823 (2016)."},{"key":"BFsrep40320_CR49","doi-asserted-by":"publisher","first-page":"1453","DOI":"10.1016\/S0140-6736(07)61602-X","volume":"370","author":"E von Elm","year":"2007","unstructured":"von Elm, E. et al. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet. 370, 1453\u20137 (2007).","journal-title":"Lancet."},{"key":"BFsrep40320_CR50","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1214\/aoms\/1177729756","volume":"21","author":"MF Freeman","year":"1950","unstructured":"Freeman, M. F. & Tukey, J. W. Transformations Related to the Angular and the Square Root. Ann Math Stats. 21, 607\u2013611 (1950).","journal-title":"Ann Math Stats"},{"key":"BFsrep40320_CR51","doi-asserted-by":"publisher","first-page":"985","DOI":"10.3109\/14397595.2014.894489","volume":"24","author":"D Fan","year":"2014","unstructured":"Fan, D. et al. Association between KIR polymorphisms and ankylosing spondylitis in populations: a meta-analysis. Mod Rheumatol. 24, 985\u201391 (2014).","journal-title":"Mod Rheumatol"},{"key":"BFsrep40320_CR52","doi-asserted-by":"publisher","first-page":"252","DOI":"10.3899\/jrheum.140416","volume":"42","author":"D Fan","year":"2015","unstructured":"Fan, D. et al. Male sexual dysfunction and ankylosing spondylitis: a systematic review and metaanalysis. J Rheumatol. 42, 252\u20137 (2015).","journal-title":"J Rheumatol."},{"key":"BFsrep40320_CR53","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","volume":"315","author":"M Egger","year":"1997","unstructured":"Egger, M. et al. Bias in meta-analysis detected by a simple, graphical test. BMJ. 315, 629\u201334 (1997).","journal-title":"BMJ."},{"key":"BFsrep40320_CR54","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.2307\/2533446","volume":"50","author":"CB Begg","year":"1994","unstructured":"Begg, C. B. & Mazumdar, M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 50, 1088\u2013101 (1994).","journal-title":"Biometrics."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/srep40320.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/srep40320","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/srep40320.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,24]],"date-time":"2022-12-24T00:51:30Z","timestamp":1671843090000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/srep40320"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,9]]},"references-count":54,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2017,2,3]]}},"alternative-id":["BFsrep40320"],"URL":"https:\/\/doi.org\/10.1038\/srep40320","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,9]]},"assertion":[{"value":"18 May 2016","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 December 2016","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 January 2017","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing financial interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"40320"}}