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Transient expression of\n                    <jats:italic>MoSM1<\/jats:italic>\n                    in rice leaves initiated hypersensitive response and upregulated expression of defense genes. When transiently expressed in tobacco leaves, MoSM1 targeted to plasma membrane. The\n                    <jats:italic>MoSM1<\/jats:italic>\n                    -overexpressing (MoSM1-OE) transgenic rice lines showed an improved resistance, as revealed by the reduced disease severity and decreased\n                    <jats:italic>in planta<\/jats:italic>\n                    pathogen growth, against 2 strains belonging to two different races of\n                    <jats:italic>M. oryzae<\/jats:italic>\n                    , causing blast disease, and against 2 strains of\n                    <jats:italic>Xanthomonas oryzae<\/jats:italic>\n                    pv.\n                    <jats:italic>oryzae<\/jats:italic>\n                    , causing bacterial leaf blight disease. However, no alteration in resistance to sheath blight disease was observed in MoSM1-OE lines. The MoSM1-OE plants contained elevated levels of salicylic acid (SA) and jasmonic acid (JA) and constitutively activated the expression of SA and JA signaling-related regulatory and defense genes. Furthermore, the MoSM1-OE plants had no effect on drought and salt stress tolerance and on grain yield. We conclude that MoSM1 confers a broad-spectrum resistance against different pathogens through modulating SA- and JA-mediated signaling pathways without any penalty on abiotic stress tolerance and grain yield, providing a promising potential for application of MoSM1 in improvement of disease resistance in crops.\n                  <\/jats:p>","DOI":"10.1038\/srep41037","type":"journal-article","created":{"date-parts":[[2017,1,20]],"date-time":"2017-01-20T05:32:09Z","timestamp":1484890329000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["Overexpression of MoSM1, encoding for an immunity-inducing protein from Magnaporthe oryzae, in rice confers broad-spectrum resistance against fungal and bacterial diseases"],"prefix":"10.1038","volume":"7","author":[{"given":"Yongbo","family":"Hong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yayun","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huijuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dayong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fengming","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,1,20]]},"reference":[{"key":"BFsrep41037_CR1","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1038\/nature05286","volume":"444","author":"JD Jones","year":"2006","unstructured":"Jones, J. 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