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This study was designed to evaluate the predictive ability of renal elasticity in patients with chronic kidney disease (CKD). 148 non-CKD patients and 227 patients with CKD were recruited. 145 (38.7%) were female, 166 (73.1%) had diabetes, the mean estimated glomerular filtration rate (eGFR) was 33.9\u2009\u00b1\u200915.8\u2009ml\/min\/1.73\u2009m\n                    <jats:sup>2<\/jats:sup>\n                    and the median urinary protein-to-creatinine ratio (UPCR) 502 (122\u20131491)\u2009mg\/g. Patients with later stages of CKD had lower renal elasticity values, indicating stiffer kidneys (p\u2009&lt;\u20090.001), and smaller kidney (p\u2009&lt;\u20090.001). Renal elasticity correlated with log-transformed UPCR (\u03b2\u2009=\u2009\u22127.544,\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.001). Renal length correlated with age (\u03b2\u2009=\u2009\u22120.231,\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.001), sex (\u03b2\u2009=\u2009\u22123.730,\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.001), serum albumin level (\u03b2\u2009=\u2009\u22123.024,\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.001), body mass index (\u03b2\u2009=\u20090.390,\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.009) and eGFR (\u03b2\u2009=\u20090.146,\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.001). In fully-adjusted logistic regression model, the odds ratio (OR) per 10 unit change in renal elasticity for rapid renal deterioration was 0.928 (95% CI, 0.864\u20130.997;\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.042). The OR per 1\u2009mm change in renal length for rapid renal deterioration was 1.022 (95% CI, 0.994\u20131.050;\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.125). Renal elasticity is associated with proteinuria and rapid renal deterioration in patients with CKD.\n                  <\/jats:p>","DOI":"10.1038\/srep43303","type":"journal-article","created":{"date-parts":[[2017,2,27]],"date-time":"2017-02-27T05:13:30Z","timestamp":1488172410000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["Association of Renal Elasticity and Renal Function Progression in Patients with Chronic Kidney Disease Evaluated by Real-Time Ultrasound Elastography"],"prefix":"10.1038","volume":"7","author":[{"given":"Hugo You-Hsien","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Li","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun-Der","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Wen","family":"Chiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shyi-Jang","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shang-Jyh","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hung-Chun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi-Chih","family":"Hung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,2,27]]},"reference":[{"key":"BFsrep43303_CR1","doi-asserted-by":"publisher","first-page":"1296","DOI":"10.1016\/s0140-6736(09)62004-3","volume":"375","author":"MT James","year":"2010","unstructured":"James, M. 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