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In particular, various studies have shown blunted neural and behavioral responses to the experience of reward in depression. However, little is known about whether depression affects individuals\u2019 valuation of potential rewards during decision-making, independent from reward experience. To address this question, we used a gambling task and a model-based analytic approach to measure two types of individual sensitivity to reward values in participants with MDD: \u2018risk preference,\u2019 indicating how objective values are subjectively perceived, and \u2018inverse temperature,\u2019 determining the degree to which subjective value differences between options influence participants\u2019 choices. On both of these measures of value sensitivity, participants with MDD were comparable to non-psychiatric controls. In addition, both risk preference and inverse temperature were stable over four laboratory visits and comparable between the groups at each visit. Neither valuation measure varied with severity of clinical symptoms in MDD. These data suggest intact and stable value processing in MDD during risky decision-making.<\/jats:p>","DOI":"10.1038\/srep44374","type":"journal-article","created":{"date-parts":[[2017,3,10]],"date-time":"2017-03-10T05:27:51Z","timestamp":1489123671000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Valuation in major depression is intact and stable in a non-learning environment"],"prefix":"10.1038","volume":"7","author":[{"given":"Dongil","family":"Chung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Kadlec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason A.","family":"Aimone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"McCurry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brooks","family":"King-Casas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pearl H.","family":"Chiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,3,10]]},"reference":[{"key":"BFsrep44374_CR1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2045-5380-3-1","volume":"3","author":"QJ Huys","year":"2013","unstructured":"Huys, Q. 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