{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T01:46:04Z","timestamp":1787535964776,"version":"build-2736575974"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,3,31]],"date-time":"2017-03-31T00:00:00Z","timestamp":1490918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2017,3,31]],"date-time":"2017-03-31T00:00:00Z","timestamp":1490918400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Extended exposure to sunlight may give rise to chemical and physical damages of human hairs. In this work, we report a novel method for non-destructive quantification of hair photodamage <jats:italic>via<\/jats:italic> multispectral imaging (MSI) technology. We show that the multispectral reflectance value in near-infrared region has a strong correlation with hair photodamage. More specifically, the hair segments with longer growing time and the same hair root segment after continuous ultraviolet (UV) irradiation displaying more severe photodamage observed <jats:italic>via<\/jats:italic> scanning electron microscopy (SEM) micrographs showed significantly higher multispectral reflectance value. Besides, the multispectral reflectance value of hair segments with different growing time was precisely reproduced by exposing the same hair root segment to specific durations of UV irradiation, suggesting that MSI can be adequately applied to determine the sunlight exposure time of the hair. The loss of cystine content of photodamaged hairs was identified to be the main factor that physiologically contributed to the morphological changes of hair surface fibers and hence the variation of their multispectral reflectance spectra. Considering the environmental information recording nature of hairs, we believe that MSI for non-destructive evaluation of hair photodamage would prove valuable for assessing sunlight exposure time of a subject in the biomedical fields.<\/jats:p>","DOI":"10.1038\/srep45544","type":"journal-article","created":{"date-parts":[[2017,3,31]],"date-time":"2017-03-31T10:52:35Z","timestamp":1490957555000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["A novel method for non-destructive determination of hair photo-induced damage based on multispectral imaging technology"],"prefix":"10.1038","volume":"7","author":[{"given":"Yue","family":"Cao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Can","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changhong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,3,31]]},"reference":[{"key":"BFsrep45544_CR1","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.jphotobiol.2004.03.001","volume":"74","author":"ACS Nogueira","year":"2004","unstructured":"Nogueira, A. C. S. & Joekes, I. Hair color changes and protein damage caused by ultraviolet radiation. J. Photoch. Photobio. B 74, 109\u2013117 (2004).","journal-title":"J. Photoch. Photobio. B"},{"key":"BFsrep45544_CR2","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1016\/j.jphotobiol.2016.06.002","volume":"161","author":"M Richena","year":"2016","unstructured":"Richena, M. & Rezende, C. A. Morphological degradation of human hair cuticle due to simulated sunlight irradiation and washing. J. Photoch. Photobio. B 161, 430\u2013440 (2016).","journal-title":"J. Photoch. Photobio. B"},{"key":"BFsrep45544_CR3","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1007\/s00414-012-0766-7","volume":"127","author":"E Han","year":"2013","unstructured":"Han, E., Yang, H., Seol, I., Park, Y., Lee, B. & Song, J. M. Segmental hair analysis and estimation of methamphetamine use pattern. Int. J. Legal Med. 127, 405\u2013411 (2013).","journal-title":"Int. J. Legal Med."},{"key":"BFsrep45544_CR4","doi-asserted-by":"publisher","first-page":"54","DOI":"10.5021\/ad.2013.25.1.54","volume":"25","author":"JH Ji","year":"2013","unstructured":"Ji, J. H. et al. The ethnic differences of the damage of hair and integral hair lipid after ultra violet radiation. Ann. Dermatol. 25, 54\u201360 (2013).","journal-title":"Ann. Dermatol."},{"key":"BFsrep45544_CR5","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1111\/ics.12054","volume":"35","author":"VM Longo","year":"2013","unstructured":"Longo, V. M., Silva, Pinheiro, A., Sambrano, J. R. et al. Towards an insight on photodamage in hair fibre by UV\u2010light: An experimental and theoretical study. Int. J. Cosmetic Sci. 35, 539\u2013545 (2013).","journal-title":"Int. J. Cosmetic Sci."},{"key":"BFsrep45544_CR6","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1111\/ics.12247","volume":"38","author":"X Li","year":"2016","unstructured":"Li, X., Hu, J., Chen, L. & Zhang, W. The adsorption behaviour and photoprotection effect of UV filter absorbed on the surface of human hair. Int. J. Cosmetic. Sci. 38, 52\u201359 (2016).","journal-title":"Int. J. Cosmetic. Sci."},{"key":"BFsrep45544_CR7","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/j.jphotobiol.2015.09.025","volume":"153","author":"MF Dario","year":"2015","unstructured":"Dario, M. F., Baby, A. R. & Velasco, M. V. R. Effects of solar radiation on hair and photoprotection. J. Photoch. Photobio. B 153, 240\u2013246 (2015).","journal-title":"J. Photoch. Photobio. B"},{"key":"BFsrep45544_CR8","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1016\/j.jphotobiol.2014.09.008","volume":"140","author":"MV Fedorkova","year":"2014","unstructured":"Fedorkova, M. V. et al. Effects of ultra violet radiation on the soluble proteins of human hair. J. Photoch. Photobio. B 140, 390\u2013395 (2014).","journal-title":"J. Photoch. Photobio. B"},{"key":"BFsrep45544_CR9","doi-asserted-by":"publisher","first-page":"12222","DOI":"10.3390\/ijms140612222","volume":"14","author":"J D\u2019Orazio","year":"2013","unstructured":"D\u2019Orazio, J., Jarrett, S., Amaro-Ortiz, A. & Scott, T. UV radiation and the skin. Int. J. Mol. Sci. 14, 12222\u201312248 (2013).","journal-title":"Int. J. Mol. Sci."},{"key":"BFsrep45544_CR10","doi-asserted-by":"crossref","unstructured":"Krutmann, J., Bouloc, A., Sore, G., Bernard, B. A. & Passeron, T. The skin aging exposome. J. Dermatol. Sci (2016).","DOI":"10.1016\/j.jdermsci.2016.09.015"},{"key":"BFsrep45544_CR11","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.plipres.2016.03.004","volume":"63","author":"E Damiani","year":"2016","unstructured":"Damiani, E. & Ullrich, S. E. Understanding the connection between platelet-activating factor, a UV-induced lipid mediator of inflammation, immune suppression and skin cancer. Prog. Lipid Res. 63, 14\u201327 (2016).","journal-title":"Prog. Lipid Res."},{"key":"BFsrep45544_CR12","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.pbiomolbio.2006.02.011","volume":"92","author":"RP Gallagher","year":"2006","unstructured":"Gallagher, R. P. & Lee, T. K. Adverse effects of ultraviolet radiation: a brief review. Prog. Biophys. Mol. Bio. 92, 119\u2013131 (2006).","journal-title":"Prog. Biophys. Mol. Bio."},{"key":"BFsrep45544_CR13","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1038\/nri3045","volume":"11","author":"PH Hart","year":"2011","unstructured":"Hart, P. H., Gorman, S. & Finlay Jones, J. J. Modulation of the immune system by UV radiation: more than just the effects of vitamin D? Nat. Rev. Immunol. 11, 584\u2013596 (2011).","journal-title":"Nat. Rev. Immunol."},{"key":"BFsrep45544_CR14","first-page":"23","volume":"158","author":"A Cranney","year":"2007","unstructured":"Cranney, A. et al. Effectiveness and safety of vitamin D in relation to bone health. Evid. Rep. Technol. Assess. (Full Rep) 158, 23\u20135 (2007).","journal-title":"Evid. Rep. Technol. Assess. (Full Rep)"},{"key":"BFsrep45544_CR15","doi-asserted-by":"publisher","first-page":"1581","DOI":"10.1093\/jnci\/djn360","volume":"100","author":"RT Chlebowski","year":"2008","unstructured":"Chlebowski, R. T. et al. Calcium plus vitamin D supplementation and the risk of breast cancer. J. Natl. Cancer. I. 100, 1581\u20131591 (2008).","journal-title":"J. Natl. Cancer. I."},{"key":"BFsrep45544_CR16","first-page":"A160","volume":"116","author":"MN Mead","year":"2008","unstructured":"Mead, M. N. Benefits of sunlight: a bright spot for human health. Environ. Health. Persp. 116, A160\u2013A167 (2008).","journal-title":"Environ. Health. Persp."},{"key":"BFsrep45544_CR17","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.jphotobiol.2011.10.011","volume":"106","author":"E Fern\u00e1ndez","year":"2012","unstructured":"Fern\u00e1ndez, E. et al. Photodamage determination of human hair. J. Photoch. Photobio. B 106, 101\u2013106 (2012).","journal-title":"J. Photoch. Photobio. B"},{"key":"BFsrep45544_CR18","first-page":"109","volume":"44","author":"CM Pande","year":"1993","unstructured":"Pande, C. M. & Jachowicz, J. Hair photodamage-Measurement and prevention. J. Soc. Cosmet. Chem. 44, 109\u2013109 (1993).","journal-title":"J. Soc. Cosmet. Chem."},{"key":"BFsrep45544_CR19","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1039\/B504970A","volume":"5","author":"S Claerhout","year":"2006","unstructured":"Claerhout, S., Van Leathem, A., Agostinis, P. & Garmyn, M. Pathways involved in sunburn cell formation: deregulation in skin cancer. Photoch. Photobio. Sci. 5, 199\u2013207 (2006).","journal-title":"Photoch. Photobio. Sci."},{"key":"BFsrep45544_CR20","doi-asserted-by":"publisher","first-page":"3835","DOI":"10.1016\/S0032-3861(97)10299-3","volume":"39","author":"N Nishikawa","year":"1998","unstructured":"Nishikawa, N., Tanizawa, Y., Tanaka, S., Horiguchi, Y. & Asakura, T. Structural change of keratin protein in human hair by permanent waving treatment. Polymer 39, 3835\u20133840 (1998).","journal-title":"Polymer"},{"key":"BFsrep45544_CR21","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1002\/bip.20453","volume":"81","author":"A Kuzuhara","year":"2006","unstructured":"Kuzuhara, A. Analysis of structure changes in bleached keratin fibers (Black and White human hair) using Raman spectroscopy. Biopolymer 81, 506\u2013514 (2006).","journal-title":"Biopolymer"},{"key":"BFsrep45544_CR22","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1111\/j.1467-2494.1987.tb00467.x","volume":"9","author":"S Hilterhaus-Bong","year":"1987","unstructured":"Hilterhaus-Bong, S. & Zahn, H. Contribution to the chemistry of human hair. I. Analyses of cystine, cysteine and cystine oxides in untreated human hair. Int. J. Cosmetic. Sci. 9, 101\u2013110 (1987).","journal-title":"Int. J. Cosmetic. Sci."},{"key":"BFsrep45544_CR23","doi-asserted-by":"publisher","first-page":"5255","DOI":"10.1002\/app.24774","volume":"102","author":"RA Lodge","year":"2006","unstructured":"Lodge, R. A. & Bhushan, B. Wetting properties of human hair by means of dynamic contact angle measurement. J. Appl. Polym. Sci. 102, 5255\u20135265 (2006).","journal-title":"J. Appl. Polym. Sci."},{"key":"BFsrep45544_CR24","first-page":"85","volume":"58","author":"KR Ramaprasad","year":"2006","unstructured":"Ramaprasad, K. R., Nori, M. & Kamath, Y. K. Redefining hair baseline parameters in some claims work. J. Cosmet. Sci. 58, 85\u201387 (2006).","journal-title":"J. Cosmet. Sci."},{"key":"BFsrep45544_CR25","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1016\/j.jphotobiol.2015.10.008","volume":"153","author":"M Richena","year":"2015","unstructured":"Richena, M. & Rezende, C. A. Effect of photodamage on the outermost cuticle layer of human hair. J. Photoch. Photobio. B 153, 296\u2013304 (2015).","journal-title":"J. Photoch. Photobio. B"},{"key":"BFsrep45544_CR26","first-page":"147","volume":"61","author":"H Tanamachi","year":"2010","unstructured":"Tanamachi, H., Tokunaga, S., Tanji, N., Oguri, M. & Inoue, S. 18-MEA and hair appearance. J. Cosmet. Sci. 61, 147\u2013160 (2010).","journal-title":"J. Cosmet. Sci."},{"key":"BFsrep45544_CR27","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.jphotobiol.2012.09.009","volume":"117","author":"E Fern\u00e1ndez","year":"2012","unstructured":"Fern\u00e1ndez, E., Mart\u00ednez-Teipel, B., Armengol, R., Barba, C. & Coderch, L. Efficacy of antioxidants in human hair. J. Photoch. Photobio. B 117, 146\u2013156 (2012).","journal-title":"J. Photoch. Photobio. B"},{"key":"BFsrep45544_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1017\/S0021859614001142","volume":"154","author":"CH Liu","year":"2016","unstructured":"Liu, C. H. et al. Non-destructive discrimination of conventional and glyphosate-resistant soybean seeds and their hybrid descendants using multispectral imaging and chemometric methods. J. Agr. Sci. 154, 1\u201312 (2016).","journal-title":"J. Agr. Sci."},{"key":"BFsrep45544_CR29","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.jphotobiol.2016.09.021","volume":"164","author":"MV Fedorkova","year":"2016","unstructured":"Fedorkova, M. V. et al. Photoinduced formation of thiols in human hair. J. Photoch. Photobio. B 164, 43\u201348 (2016).","journal-title":"J. Photoch. Photobio. B"},{"key":"BFsrep45544_CR30","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.forsciint.2011.02.015","volume":"210","author":"MA LeBeau","year":"2011","unstructured":"LeBeau, M. A., Montgomery, M. A. & Brewer, J. D. The role of variations in growth rate and sample collection on interpreting results of segmental analyses of hair. Forensic Sci. Int. 210, 110\u2013116 (2011).","journal-title":"Forensic Sci. Int."},{"key":"BFsrep45544_CR31","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1366\/12-06823","volume":"67","author":"MG Ljungqvist","year":"2013","unstructured":"Ljungqvist, M. G., Frosch, S., Nielsen, M. E. & Ersb\u00f8ll, B. K. Multispectral image analysis for robust prediction of astaxanthin coating. Appl. Spectrosc. 67, 738\u2013746 (2013).","journal-title":"Appl. Spectrosc."},{"key":"BFsrep45544_CR32","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.foodchem.2013.11.166","volume":"153","author":"CH Liu","year":"2014","unstructured":"Liu, C. H. et al. Nondestructive determination of transgenic Bacillus thuringiensis rice seeds (Oryza sativa L.) using multispectral imaging and chemometric methods. Food Chem. 153, 87\u201393 (2014).","journal-title":"Food Chem."},{"key":"BFsrep45544_CR33","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1134\/S1054661813020089","volume":"23","author":"G Chen","year":"2013","unstructured":"Chen, G., Bui, T. D., Krzyzak, A. & Krishnan, S. Small bowel image classification based on Fourier-Zernike moment features and canonical discriminant analysis. Pattern Recognit. Image Anal. 23, 211\u2013216 (2013).","journal-title":"Pattern Recognit. Image Anal."},{"key":"BFsrep45544_CR34","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1111\/j.1346-8138.2010.00916.x","volume":"37","author":"MS Jeong","year":"2010","unstructured":"Jeong, M. S., Lee, C. M., Jeong, W. J., Kim, S. J. & Lee, K. Y. Significant damage of the skin and hair following hair bleaching. J. Dermatol. 37, 882\u2013887 (2010).","journal-title":"J. Dermatol."},{"key":"BFsrep45544_CR35","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1111\/ics.12201","volume":"37","author":"N Ali","year":"2015","unstructured":"Ali, N., Zohra, R. R., Qader, S. A. U. & Mumtaz, M. Scanning electron microscopy analysis of hair index on Karachi\u2019s population for social and professional appearance enhancement. Int. J. Cosmetic Sci. 37, 312\u2013320 (2015).","journal-title":"Int. J. Cosmetic Sci."},{"key":"BFsrep45544_CR36","doi-asserted-by":"publisher","first-page":"94","DOI":"10.4103\/0974-7753.188035","volume":"8","author":"F Kaliyadan","year":"2016","unstructured":"Kaliyadan, F. et al. Scanning electron microscopy study of hair shaft damage secondary to cosmetic treatments of the hair. Int. J. Trichology 8, 94\u201398 (2016).","journal-title":"Int. J. Trichology"}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/srep45544.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/srep45544","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/doifinder\/10.1038\/srep45544","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/www.nature.com\/articles\/srep45544.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,24]],"date-time":"2022-12-24T00:14:52Z","timestamp":1671840892000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/srep45544"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,31]]},"references-count":36,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2017,4,24]]}},"alternative-id":["BFsrep45544"],"URL":"https:\/\/doi.org\/10.1038\/srep45544","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,31]]},"assertion":[{"value":"17 November 2016","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 February 2017","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 March 2017","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing financial interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"45544"}}