{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T19:27:56Z","timestamp":1760297276993},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"5967","license":[{"start":{"date-parts":[[1984,5,1]],"date-time":"1984-05-01T00:00:00Z","timestamp":452217600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[1984,5]]},"DOI":"10.1038\/309448a0","type":"journal-article","created":{"date-parts":[[2004,11,18]],"date-time":"2004-11-18T02:53:21Z","timestamp":1100746401000},"page":"448-450","source":"Crossref","is-referenced-by-count":55,"title":["Threshold channels\u2014a novel type of sodium channel in squid giant axon"],"prefix":"10.1038","volume":"309","author":[{"given":"Wm. F.","family":"Gilly","sequence":"first","affiliation":[]},{"given":"Clay M.","family":"Armstrong","sequence":"additional","affiliation":[]}],"member":"297","reference":[{"key":"BF309448a0_CR1","first-page":"118","volume-title":"Membrane Potential-dependent Ion Channels in Cell Membranes: Phylogenetic and Developmental Approaches","author":"S Hagiwara","year":"1983","unstructured":"Hagiwara, S. Membrane Potential-dependent Ion Channels in Cell Membranes: Phylogenetic and Developmental Approaches, 118 (Raven, New York, 1983)."},{"key":"BF309448a0_CR2","first-page":"49","volume-title":"The Cell Surface and Neuronal Function","author":"SH Thompson","year":"1980","unstructured":"Thompson, S. H. & Aldrich, R. W. in The Cell Surface and Neuronal Function (eds Cotman, C. W., Poste, G. & Nicolson, G. L.) 49\u201385 (Elsevier, Amsterdam, 1980)."},{"key":"BF309448a0_CR3","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1113\/jphysiol.1981.sp013865","volume":"318","author":"JM Dubois","year":"1981","unstructured":"Dubois, J. M. J. Physiol., Lond. 318, 297\u2013316 (1981).","journal-title":"J. Physiol., Lond."},{"key":"BF309448a0_CR4","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1113\/jphysiol.1980.sp013403","volume":"306","author":"PA Pappone","year":"1980","unstructured":"Pappone, P. A. J. Physiol., Lond. 306, 377\u2013410 (1980).","journal-title":"J. Physiol., Lond."},{"key":"BF309448a0_CR5","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/S0006-3495(84)84113-2","volume":"45","author":"R Ten Eick","year":"1984","unstructured":"Ten Eick, R., Yeh, J. & Matsuki, N. Biophys. J. 45, 70\u201373 (1984).","journal-title":"Biophys. J."},{"key":"BF309448a0_CR6","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1113\/jphysiol.1980.sp013358","volume":"305","author":"R Llinas","year":"1980","unstructured":"Llinas, R. & Sugimori, M. J. Physiol., Lond. 305, 197\u2013213 (1980).","journal-title":"J. Physiol., Lond."},{"key":"BF309448a0_CR7","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1085\/jgp.79.5.739","volume":"79","author":"DR Mattesen","year":"1982","unstructured":"Mattesen, D. R. & Armstrong, C. M. J. gen. Physiol. 79, 739\u2013758 (1982).","journal-title":"J. gen. Physiol."},{"key":"BF309448a0_CR8","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1085\/jgp.63.5.533","volume":"63","author":"CM Armstrong","year":"1974","unstructured":"Armstrong, C. M. & Bezanilla, F. J. gen.Physiol. 63, 533\u2013552 (1974).","journal-title":"J. gen.Physiol."},{"key":"BF309448a0_CR9","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1085\/jgp.74.6.691","volume":"74","author":"CM Armstrong","year":"1979","unstructured":"Armstrong, C. M. & Gilly, W. F. J. gen. Physiol 74, 691\u2013711 (1979).","journal-title":"J. gen. Physiol"},{"key":"BF309448a0_CR10","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1113\/jphysiol.1952.sp004764","volume":"117","author":"AL Hodgkin","year":"1952","unstructured":"Hodgkin, A. L. & Huxley, A. F. J. Physiol, Lond. 117, 500\u2013544 (1952).","journal-title":"J. Physiol, Lond."},{"key":"BF309448a0_CR11","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1085\/jgp.79.6.935","volume":"79","author":"WF Gilly","year":"1983","unstructured":"Gilly, W. F. & Armstrong, C. M. J. gen. Physiol. 79, 935\u2013964 (1983).","journal-title":"J. gen. Physiol."},{"key":"BF309448a0_CR12","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1085\/jgp.77.1.1","volume":"77","author":"GS Oxford","year":"1981","unstructured":"Oxford, G. S. J. gen. Physiol. 77, 1\u201322 (1981).","journal-title":"J. gen. Physiol."},{"key":"BF309448a0_CR13","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1113\/jphysiol.1983.sp014581","volume":"336","author":"JW Moore","year":"1983","unstructured":"Moore, J. W. & Westerfield, M. J. Physiol., Lond. 336, 285\u2013300 (1983).","journal-title":"J. Physiol., Lond."},{"key":"BF309448a0_CR14","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1113\/jphysiol.1983.sp014582","volume":"336","author":"JW Moore","year":"1983","unstructured":"Moore, J. W., Stockbridge, N. & Westerfield, M. J. Physiol., Lond. 336, 301\u2013311 (1983).","journal-title":"J. Physiol., Lond."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/309448a0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/309448a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/309448a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T01:23:34Z","timestamp":1684286614000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/309448a0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,5]]},"references-count":14,"journal-issue":{"issue":"5967","published-print":{"date-parts":[[1984,5]]}},"alternative-id":["BF309448a0"],"URL":"https:\/\/doi.org\/10.1038\/309448a0","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,5]]}}}