{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:26:04Z","timestamp":1791267964463,"version":"4.1.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"6554","license":[{"start":{"date-parts":[[1995,11,1]],"date-time":"1995-11-01T00:00:00Z","timestamp":815184000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[1995,11]]},"DOI":"10.1038\/378287a0","type":"journal-article","created":{"date-parts":[[2003,6,12]],"date-time":"2003-06-12T23:59:47Z","timestamp":1055462387000},"page":"287-292","source":"Crossref","is-referenced-by-count":1268,"title":["Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor"],"prefix":"10.1038","volume":"378","author":[{"given":"Joan","family":"Vaughan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia","family":"Donaldson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jackson","family":"Bittencourt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marilyn H.","family":"Perrin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathy","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Sutton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew V.","family":"Turnbull","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Lovejoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Rivier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Rivier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul E.","family":"Sawchenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wylie","family":"Vale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BF378287a0_CR1","doi-asserted-by":"publisher","first-page":"1394","DOI":"10.1126\/science.6267699","volume":"213","author":"W Vale","year":"1981","unstructured":"Vale, W., Spiess, J., Rivier, C. & Rivier, J. Science 213, 1394\u20131397 (1981).","journal-title":"Science"},{"key":"BF378287a0_CR2","first-page":"245","volume-title":"Chemical and Biological Characterization of Corticotropin Releasing Factor in Recent Progress in Hormone Research","author":"W Vale","year":"1983","unstructured":"Vale, W. et al. Chemical and Biological Characterization of Corticotropin Releasing Factor in Recent Progress in Hormone Research, Vol. 39, 245\u2013270 (Academic, San Diego, 1983)."},{"key":"BF378287a0_CR3","first-page":"67","volume-title":"Fish Physiology","author":"K Lederis","year":"1994","unstructured":"Lederis, K., Fryer, J. N., Okawara, Y., Schonrock, C. & Richter, D. in Fish Physiology (ed. Farrell, A.) 67\u2013100 (Academic, San Diego, 1994)."},{"key":"BF378287a0_CR4","doi-asserted-by":"publisher","first-page":"8439","DOI":"10.1073\/pnas.85.22.8439","volume":"85","author":"Y Okawara","year":"1988","unstructured":"Okawara, Y. et al. Proc. natn. Acad. Sci. U.S.A. 85, 8439\u20138443 (1988).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF378287a0_CR5","first-page":"1716","volume":"6","author":"MP Stenzel-Poore","year":"1992","unstructured":"Stenzel-Poore, M. P., Heldwein, K. A., Stenzel, P., Lee, S. & Vale, W. W. Molec. Endocr. 6, 1716\u20131724 (1992).","journal-title":"Molec. Endocr."},{"key":"BF378287a0_CR6","doi-asserted-by":"publisher","first-page":"8967","DOI":"10.1073\/pnas.90.19.8967","volume":"90","author":"R Chen","year":"1993","unstructured":"Chen, R., Lewis, K. A., Perrin, M. H. & Vale, W. W. Proc. natn. Acad. Sci. U.S.A. 90, 8967\u20138971 (1993).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF378287a0_CR7","doi-asserted-by":"publisher","first-page":"3058","DOI":"10.1210\/endo.133.6.8243338","volume":"133","author":"MH Perrin","year":"1993","unstructured":"Perrin, M. H., Donaldson, C. J., Chen, R., Lewis, K. A. & Vale, W. W. Endocrinology 133, 3058\u20133061 (1993).","journal-title":"Endocrinology"},{"key":"BF378287a0_CR8","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.1016\/0896-6273(93)90230-O","volume":"11","author":"C Chang","year":"1993","unstructured":"Chang, C., Pearse, R., O'Connell, S. & Rosenfeld, M. G. Neuron 11, 1187\u20131195 (1993).","journal-title":"Neuron"},{"key":"BF378287a0_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0014-5793(93)80427-V","volume":"335","author":"N Vita","year":"1993","unstructured":"Vita, N. et al. FEBS Lett. 335, 1\u20135 (1993).","journal-title":"FEBS Lett."},{"key":"BF378287a0_CR10","doi-asserted-by":"publisher","first-page":"836","DOI":"10.1073\/pnas.92.3.836","volume":"92","author":"TW Lovenberg","year":"1995","unstructured":"Lovenberg, T. W. et al. Proc. natn. Acad. Sci. U.S.A. 92, 836\u2013840 (1995).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF378287a0_CR11","doi-asserted-by":"publisher","first-page":"1108","DOI":"10.1073\/pnas.92.4.1108","volume":"92","author":"T Kishimoto","year":"1995","unstructured":"Kishimoto, T., Pearse, R. V. II, Lin, C. R. & Rosenfeld, M. G. Proc. natn. Acad: Sci. U.S.A. 92, 1108\u20131112 (1995).","journal-title":"Proc. natn. Acad: Sci. U.S.A."},{"key":"BF378287a0_CR12","doi-asserted-by":"publisher","first-page":"2969","DOI":"10.1073\/pnas.92.7.2969","volume":"92","author":"M Perrin","year":"1995","unstructured":"Perrin, M. et al. Proc. natn. Acad. Sci. U.S.A. 92, 2969\u20132973 (1995).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF378287a0_CR13","first-page":"637","volume":"9","author":"P Stenzel","year":"1995","unstructured":"Stenzel, P. et al. Molec. Endocr. 9, 637\u2013645 (1995).","journal-title":"Molec. Endocr."},{"key":"BF378287a0_CR14","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/0006-8993(91)90571-C","volume":"547","author":"J Imaki","year":"1991","unstructured":"Imaki, J., Imaki, T., Vale, W. & Sawchenko, P. E. Brain Res. 547, 28\u201336 (1991).","journal-title":"Brain Res."},{"key":"BF378287a0_CR15","doi-asserted-by":"publisher","first-page":"3351","DOI":"10.1210\/endo.136.9.7544278","volume":"136","author":"TW Lovenberg","year":"1995","unstructured":"Lovenberg, T. W., Chalmers, D. T., Liu, C. & De Souza, E. B. Endocrinology 136, 3351\u20133355 (1995).","journal-title":"Endocrinology"},{"key":"BF378287a0_CR16","doi-asserted-by":"publisher","first-page":"8777","DOI":"10.1073\/pnas.91.19.8777","volume":"91","author":"E Potter","year":"1994","unstructured":"Potter, E. et al. Proc. natn. Acad. Sci. U.S.A. 91, 8777\u20138781 (1994).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF378287a0_CR17","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1073\/pnas.83.2.308","volume":"83","author":"I Ishida","year":"1986","unstructured":"Ishida, I., Ichikawa, T., & Deguchi, T. Proc. natn. Acad. Sci. U.S.A. 83, 803\u2013812 (1986).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF378287a0_CR18","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1210\/mend-1-5-363","volume":"1","author":"RC Thompson","year":"1987","unstructured":"Thompson, R. C., Seasholtz, A. F. & Herbert, E. Molec. Endocr. 1, 363\u2013370 (1987).","journal-title":"Molec. Endocr."},{"key":"BF378287a0_CR19","doi-asserted-by":"publisher","first-page":"4192","DOI":"10.1073\/pnas.89.9.4192","volume":"89","author":"E Potter","year":"1992","unstructured":"Potter, E. et al. Proc. natn. Acad. Sci. U.S.A. 89, 4192\u20134196 (1992).","journal-title":"Proc. natn. Acad. Sci. U.S.A."},{"key":"BF378287a0_CR20","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1038\/373427a0","volume":"373","author":"L Muglia","year":"1995","unstructured":"Muglia, L. Jacobson, L., Dikkes, P. & Majzoub, J. A. Nature 373, 427\u2013432 (1995).","journal-title":"Nature"},{"key":"BF378287a0_CR21","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1093\/oso\/9780195051063.003.0015","volume-title":"Central Regulation of Autonomic Functions","author":"AD Loewy","year":"1990","unstructured":"Loewy, A. D. in Central Regulation of Autonomic Functions (eds Loewy, A. D. & Spyer, K. M.) 268\u2013285 (Oxford Univ. Press, New York. 1990)."},{"key":"BF378287a0_CR22","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/0006-8993(78)90624-8","volume":"141","author":"AD Loewy","year":"1978","unstructured":"Loewy, A. D., Saper, C. B. & Yamodis, N. D. Brain Res. 141, 153\u2013159 (1978).","journal-title":"Brain Res."},{"key":"BF378287a0_CR23","first-page":"797","volume-title":"The Rat Nervous System","author":"WR Webster","year":"1995","unstructured":"Webster, W. R. in The Rat Nervous System (ed. Paxinos, G.) 797\u2013831 (Academic, San Diego. 1995)."},{"key":"BF378287a0_CR24","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1002\/cne.901830402","volume":"183","author":"CB Saper","year":"1979","unstructured":"Saper, C. B., Swanson, L. W. & Cowan, W. M. J. comp. Neuro. 183, 689\u2013706 (1979).","journal-title":"J. comp. Neuro."},{"key":"BF378287a0_CR25","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1146\/annurev.ne.14.030191.002225","volume":"14","author":"JI Morgan","year":"1991","unstructured":"Morgan, J. I. & Curran, T. A. Rev. Neurosci. 14, 421\u2013451 (1991).","journal-title":"A. Rev. Neurosci."},{"key":"BF378287a0_CR26","first-page":"553","volume":"41","author":"K Lederis","year":"1985","unstructured":"Lederis, K. et al. Rec. Prog. Horm. Res. 41, 553\u2013576 (1985).","journal-title":"Rec. Prog. Horm. Res."},{"key":"BF378287a0_CR27","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1016\/S0076-6879(83)03040-2","volume":"103","author":"W Vale","year":"1983","unstructured":"Vale, W. et al. Meth. Enzym. 103, 565\u2013577 (1983).","journal-title":"Meth. Enzym."},{"key":"BF378287a0_CR28","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1210\/endo.136.3.7867564","volume":"136","author":"SW Sutton","year":"1995","unstructured":"Sutton, S. W. et al. Endocrinology 136, 1097\u20131102 (1995).","journal-title":"Endocrinology"},{"key":"BF378287a0_CR29","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/0304-3940(87)90208-4","volume":"83","author":"RY Chung","year":"1987","unstructured":"Chung, R. Y., Mason, P., Strassman, A., Maciewicz, R. Neurosci. Lett. 83, 13\u201319 (1987).","journal-title":"Neurosci. Lett."},{"key":"BF378287a0_CR30","first-page":"5125","volume":"13","author":"RKW Chan","year":"1993","unstructured":"Chan, R. K. W., Brown, E. R., Ericsson, A., Kov\u00e1cs, K. J. & Sawchenko, P. E. J. Neurosci. 13, 5125\u20135138 (1993).","journal-title":"J. Neurosci."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/378287a0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/378287a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/378287a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T23:44:54Z","timestamp":1704843894000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/378287a0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,11]]},"references-count":30,"journal-issue":{"issue":"6554","published-print":{"date-parts":[[1995,11]]}},"alternative-id":["BF378287a0"],"URL":"https:\/\/doi.org\/10.1038\/378287a0","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,11]]}}}