{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T06:16:51Z","timestamp":1779344211035,"version":"3.51.4"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[1996,7,1]],"date-time":"1996-07-01T00:00:00Z","timestamp":836179200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Genet"],"published-print":{"date-parts":[[1996,7]]},"DOI":"10.1038\/ng0796-347","type":"journal-article","created":{"date-parts":[[2004,8,18]],"date-time":"2004-08-18T20:19:18Z","timestamp":1092860358000},"page":"347-349","source":"Crossref","is-referenced-by-count":281,"title":["Mad-related genes in the human"],"prefix":"10.1038","volume":"13","author":[{"given":"Gregory J.","family":"Riggins","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sam","family":"Thiagalingam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ester","family":"Rozenblum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Craig L.","family":"Weinstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott E.","family":"Kern","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stanley R.","family":"Hamilton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James K.V.","family":"Willson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanford D.","family":"Markowitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth W.","family":"Kinzler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bert","family":"Vogelstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BFng0796347_CR1","first-page":"493","volume":"4","author":"TM Fynan","year":"1993","unstructured":"Fynan, T.M. & Reiss, M. Resistance to inhibition of cell growth by transforming growth factor-beta and its role in oncogenesis. Crit. Rev. Oncog. 4, 493\u2013540 (1993).","journal-title":"Crit. Rev. Oncog."},{"key":"BFng0796347_CR2","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1097\/00001622-199401000-00011","volume":"6","author":"MG Brattain","year":"1994","unstructured":"Brattain, M.G., Howell, G., Sun, L.Z. & Willson, J.K., Growth factor balance and tumor progression. Curr. Opin. Oncol. 6, 77\u201381 (1994).","journal-title":"Curr. Opin. Oncol."},{"key":"BFng0796347_CR3","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1242\/dev.117.4.1211","volume":"117","author":"DA Hursh","year":"1993","unstructured":"Hursh, D.A., Padgett, R.W. & Gelbart, W.M. Cross regulation of decapentaplegic and Ultrabithorax transcription in the embryonic visceral mesoderm of Drosophila . Development 117, 1211\u20131222 (1993).","journal-title":"Development"},{"key":"BFng0796347_CR4","first-page":"1347","volume-title":"Drosophila melanogaster","author":"JJ Sekelsky","year":"1995","unstructured":"Sekelsky, J.J., Newfeld, S.J., Raftery, L.A., Chartoff, E.H. & Gelbart, W.M. Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster. Genetics 139, 1347\u20131358 (1995)."},{"key":"BFng0796347_CR5","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1073\/pnas.93.2.790","volume":"93","author":"C Savage","year":"1996","unstructured":"Savage, C. et al. Caenorhabditis elegans genes Sma2, Sma-3, and Sma-4 define a conserved family of transforming growth factor beta pathway components. Proc. Natl. Acad. Sci. USA 93, 790\u2013794 (1996).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFng0796347_CR6","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1101\/gad.8.2.133","volume":"8","author":"DM Kingsley","year":"1994","unstructured":"Kingsley, D.M. TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes. Dev. 8, 133\u2013146 (1994).","journal-title":"Genes. Dev."},{"key":"BFng0796347_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3109\/08977199309029129","volume":"8","author":"AB Roberts","year":"1993","unstructured":"Roberts, A.B. & Sporn, M.B. Physiological actions and clinical applications of transforming growth factor-beta (TGF-beta). Growth Factors 8, 1\u20139 (1993).","journal-title":"Growth Factors"},{"key":"BFng0796347_CR8","first-page":"309","volume":"14","author":"DJ Satterwhite","year":"1994","unstructured":"Satterwhite, D.J. & Moses, H.L. Mechanisms of transforming growth factor-beta 1 - induced cell cycle arrest. Inv. Metast. 14, 309\u2013318 (1994).","journal-title":"Inv. Metast."},{"key":"BFng0796347_CR9","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/S0959-437X(95)90059-4","volume":"5","author":"J Massague","year":"1995","unstructured":"Massague, J. & Polyak, K. Mammalian antiproliferative signals and their targets. Curr. Opin.Genet. Dev. 5, 91\u201396 (1995).","journal-title":"Curr. Opin.Genet. Dev."},{"key":"BFng0796347_CR10","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1126\/science.271.5247.350","volume":"271","author":"SA Hahn","year":"1996","unstructured":"Hahn, S.A. et al. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271, 350\u2013353 (1996).","journal-title":"Science"},{"key":"BFng0796347_CR11","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1006\/geno.1995.9993","volume":"29","author":"JR Korenberg","year":"1995","unstructured":"Korenberg, J.R., Chen, X.N., Adams, M.D. & Venter, J.C. Toward a cDNA Map Of the Human Genome. Genomics 29, 364\u2013370 (1995).","journal-title":"Genomics"},{"key":"BFng0796347_CR12","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1126\/science.2294591","volume":"247","author":"ER Fearon","year":"1990","unstructured":"Fearon, E.R. et al. Identification of a chromosome 18q gene that is altered in colorectal cancers. Science 247, 49\u201356 (1990).","journal-title":"Science"},{"key":"BFng0796347_CR13","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1038\/ng0796-343","volume":"13","author":"S Thiagalingam","year":"1996","unstructured":"Thiagalingam, S. et al. Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers. Nature Genet. 13, 343\u2013346 (1996).","journal-title":"Nature Genet."},{"key":"BFng0796347_CR14","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/0888-7543(95)80153-D","volume":"25","author":"K Rojas","year":"1995","unstructured":"Rojas, K., Silverman, G.A., Hudson, J.R., Jr., & Overhauser, J. Integration of the 1993-94 Genethon genetic linkage map for chromosome 18 with the physical map using a somatic cell hybrid mapping panel. Genomics. 25, 329\u2013330 (1995).","journal-title":"Genomics."},{"key":"BFng0796347_CR15","first-page":"2527","volume":"56","author":"M Schutte","year":"1996","unstructured":"Schutte, M. et al. DPC4 gene in various tumor types. Cancer Res. 56, 2527\u20132530 (1996).","journal-title":"Cancer Res."},{"key":"BFng0796347_CR16","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1053\/gast.1996.v110.pm8536888","volume":"110","author":"S Ogasawara","year":"1996","unstructured":"Ogasawara, S. et al. Common deleted region on the long arm of chromosome 5 in esophageal carcinoma. Gastroenterol. 110, 52\u201357 (1996).","journal-title":"Gastroenterol."},{"key":"BFng0796347_CR17","first-page":"97","volume":"12","author":"I Wieland","year":"1996","unstructured":"Wieland, I. et al. Allelic deletion mapping on chromosome 5 in human lung carcinomas. Oncogene. 12, 97\u2013102 (1996).","journal-title":"Oncogene."},{"key":"BFng0796347_CR18","first-page":"973","volume":"12","author":"W Wick","year":"1996","unstructured":"Wick, W. Evidence for a novel tumor suppressor gene on chromosome 15 associated with progression to a metastatic stage in breast cancer. Oncogene 12, 973\u2013978 (1996).","journal-title":"Oncogene"},{"key":"BFng0796347_CR19","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","volume":"215","author":"SF Altschul","year":"1990","unstructured":"Altschul, S.F., Gish, W., Miller, W., Myers, E.W., & Lipman, D.J., Basic local alignment search tool. J. Mol. Biol. 215, 403\u2013410 (1990).","journal-title":"J. Mol. Biol."},{"key":"BFng0796347_CR20","unstructured":"Hillier, L. Generation and preliminary analysis of over 200,000 human expressed sequence tags. Nature (in the press)."},{"key":"BFng0796347_CR21","doi-asserted-by":"publisher","first-page":"1945","DOI":"10.1126\/science.270.5244.1945","volume":"270","author":"TJ Hudson","year":"1995","unstructured":"Hudson, T.J. . et al. An STS-based map of the human genome. Science 270, 1945\u20131954 (1995).","journal-title":"Science"},{"key":"BFng0796347_CR22","doi-asserted-by":"publisher","first-page":"1982","DOI":"10.1056\/NEJM199312303292702","volume":"329","author":"SM Powell","year":"1993","unstructured":"Powell, S.M. et al. Molecular diagnosis of familial adenomatous polyposis. N. Engl. J. Med. 329, 1982\u20131987 (1993).","journal-title":"N. Engl. J. Med."},{"key":"BFng0796347_CR23","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1016\/0092-8674(93)90330-S","volume":"75","author":"FS Leach","year":"1993","unstructured":"Leach, F.S. et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 75, 1215\u20131225 (1993).","journal-title":"Cell"},{"key":"BFng0796347_CR24","doi-asserted-by":"publisher","first-page":"1625","DOI":"10.1126\/science.8128251","volume":"263","author":"N Papadopoulos","year":"1994","unstructured":"Papadopoulos, N. et al. Mutation of a mutL homolog in hereditary colon cancer. Science 263, 1625\u20131629 (1994).","journal-title":"Science"},{"key":"BFng0796347_CR25","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1002\/prot.340090304","volume":"9","author":"GD Schuler","year":"1991","unstructured":"Schuler, G.D., Altschul, S.F. & Lipman, D.J. A workbench for multiple alignment construction and analysis. Proteins. 9, 180\u2013190 (1991).","journal-title":"Proteins."},{"key":"BFng0796347_CR26","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1101\/gr.5.3.272","volume":"5","author":"R Houlgatte","year":"1995","unstructured":"Houlgatte, R. et al. The Genexpress Index - a resource for gene discovery and the genie map of the human genome. Genome Res. 5, 272\u2013304 (1995).","journal-title":"Genome Res."}],"container-title":["Nature Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/ng0796-347","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ng0796-347.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ng0796-347.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T20:48:39Z","timestamp":1684442919000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/ng0796-347"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,7]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1996,7]]}},"alternative-id":["BFng0796347"],"URL":"https:\/\/doi.org\/10.1038\/ng0796-347","relation":{},"ISSN":["1061-4036","1546-1718"],"issn-type":[{"value":"1061-4036","type":"print"},{"value":"1546-1718","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,7]]}}}