{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:22:20Z","timestamp":1778718140933,"version":"3.51.4"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Nutr"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1038\/s41430-022-01242-y","type":"journal-article","created":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T08:05:50Z","timestamp":1669881950000},"page":"546-550","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Intensity matters: impact of physical activity energy expenditure at moderate and vigorous intensity on total and abdominal obesity in children"],"prefix":"10.1038","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6230-6027","authenticated-orcid":false,"given":"Lu\u00eds B.","family":"Sardinha","sequence":"first","affiliation":[]},{"given":"Jo\u00e3o P.","family":"Magalh\u00e3es","sequence":"additional","affiliation":[]},{"given":"Diana A.","family":"Santos","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1825-8010","authenticated-orcid":false,"given":"Megan","family":"Hetherington-Rauth","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2022,12,1]]},"reference":[{"key":"1242_CR1","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1038\/pr.2015.29","volume":"77","author":"O Gishti","year":"2015","unstructured":"Gishti O, Gaillard R, Durmus B, Abrahamse M, van der Beek EM, Hofman A, et al. BMI, total and abdominal fat distribution, and cardiovascular risk factors in school-age children. Pediatr Res. 2015;77:710\u20138.","journal-title":"Pediatr Res"},{"key":"1242_CR2","doi-asserted-by":"publisher","first-page":"1623","DOI":"10.1542\/peds.2004-2588","volume":"115","author":"I Janssen","year":"2005","unstructured":"Janssen I, Katzmarzyk PT, Srinivasan SR, Chen W, Malina RM, Bouchard C, et al. Combined influence of body mass index and waist circumference on coronary artery disease risk factors among children and adolescents. Pediatrics. 2005;115:1623\u201330.","journal-title":"Pediatrics"},{"key":"1242_CR3","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1007\/s13679-021-00439-9","volume":"10","author":"A Horesh","year":"2021","unstructured":"Horesh A, Tsur AM, Bardugo A, Twig G. Adolescent and childhood obesity and excess morbidity and mortality in young adulthood\u2014a systematic review. Curr Obes Rep. 2021;10:301\u201310.","journal-title":"Curr Obes Rep"},{"key":"1242_CR4","doi-asserted-by":"publisher","first-page":"535705","DOI":"10.3389\/fped.2020.535705","volume":"8","author":"J Wyszy\u0144ska","year":"2020","unstructured":"Wyszy\u0144ska J, Ring-Dimitriou S, Thivel D, Weghuber D, Hadjipanayis A, Grossman Z, et al. Physical activity in the prevention of childhood obesity: the position of the European Childhood Obesity Group and the European Academy of Pediatrics. Front Pediatr. 2020;8:535705.","journal-title":"Front Pediatr"},{"key":"1242_CR5","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1136\/bjsports-2020-102955","volume":"54","author":"FC Bull","year":"2020","unstructured":"Bull FC, Al-Ansari SS, Biddle S, Borodulin K, Buman MP, Cardon G, et al. World Health Organization 2020 guidelines on physical activity and sedentary behaviour. Br J Sports Med. 2020;54:1451\u201362.","journal-title":"Br J Sports Med"},{"key":"1242_CR6","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1177\/1559827615624417","volume":"13","author":"MH Gralla","year":"2019","unstructured":"Gralla MH, McDonald SM, Breneman C, Beets MW, Moore JB. Associations of objectively measured vigorous physical activity with body composition, cardiorespiratory fitness, and cardiometabolic health in youth: a review. Am J Lifestyle Med. 2019;13:61\u201397.","journal-title":"Am J Lifestyle Med"},{"key":"1242_CR7","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1177\/1559827615594585","volume":"11","author":"S Owens","year":"2017","unstructured":"Owens S, Galloway R, Gutin B. The case for vigorous physical activity in youth. Am J Lifestyle Med. 2017;11:96\u2013115.","journal-title":"Am J Lifestyle Med"},{"key":"1242_CR8","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.1093\/ije\/dys038","volume":"41","author":"I Janssen","year":"2012","unstructured":"Janssen I, Ross R. Vigorous intensity physical activity is related to the metabolic syndrome independent of the physical activity dose. Int J Epidemiol. 2012;41:1132\u201340.","journal-title":"Int J Epidemiol"},{"key":"1242_CR9","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1055\/s-0030-1261935","volume":"31","author":"V Espa\u00f1a-Romero","year":"2010","unstructured":"Espa\u00f1a-Romero V, Ortega FB, Ruiz JR, Artero EG, Mart\u00ednez-G\u00f3mez D, Vicente-Rodriguez G, et al. Role of cardiorespiratory fitness on the association between physical activity and abdominal fat content in adolescents: the HELENA study. Int J Sports Med. 2010;31:679\u201382.","journal-title":"Int J Sports Med"},{"key":"1242_CR10","first-page":"373","volume":"79","author":"World Medical Association.","year":"2001","unstructured":"World Medical Association. World Medical Association Declaration of Helsinki. Ethical principles for medical research involving human subjects. Bull World Health Organ. 2001;79:373\u20134.","journal-title":"Bull World Health Organ"},{"key":"1242_CR11","doi-asserted-by":"publisher","first-page":"S523","DOI":"10.1249\/01.mss.0000185658.28284.ba","volume":"37","author":"P Freedson","year":"2005","unstructured":"Freedson P, Pober D, Janz KF. Calibration of accelerometer output for children. Med Sci Sport Exer. 2005;37:S523\u2013S30.","journal-title":"Med Sci Sport Exer"},{"key":"1242_CR12","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1249\/mss.0b013e31815a51b3","volume":"40","author":"RP Troiano","year":"2008","unstructured":"Troiano RP, Berrigan D, Dodd KW, Masse LC, Tilert T, McDowell M. Physical activity in the United States measured by accelerometer. Med Sci Sports Exerc. 2008;40:181\u20138.","journal-title":"Med Sci Sports Exerc"},{"key":"1242_CR13","doi-asserted-by":"publisher","first-page":"1557","DOI":"10.1080\/02640410802334196","volume":"26","author":"KR Evenson","year":"2008","unstructured":"Evenson KR, Catellier DJ, Gill K, Ondrak KS, McMurray RG. Calibration of two objective measures of physical activity for children. J Sports Sci. 2008;26:1557\u201365.","journal-title":"J Sports Sci"},{"key":"1242_CR14","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1007\/BF00418508","volume":"58","author":"HS Hansen","year":"1989","unstructured":"Hansen HS, Froberg K, Nielsen JR, Hyldebrandt N. A new approach to assessing maximal aerobic power in children: the Odense School Child Study. Eur J Appl Physiol Occup Physiol. 1989;58:618\u201324.","journal-title":"Eur J Appl Physiol Occup Physiol"},{"key":"1242_CR15","doi-asserted-by":"publisher","first-page":"1699","DOI":"10.3390\/biom10121699","volume":"10","author":"A Muscella","year":"2020","unstructured":"Muscella A, Stef\u00e0no E, Lunetti P, Capobianco L, Marsigliante S. The regulation of fat metabolism during aerobic exercise. Biomolecules. 2020;10:1699.","journal-title":"Biomolecules"},{"key":"1242_CR16","doi-asserted-by":"publisher","first-page":"868305","DOI":"10.1155\/2011\/868305","volume":"2011","author":"SH Boutcher","year":"2011","unstructured":"Boutcher SH. High-intensity intermittent exercise and fat loss. J Obes. 2011;2011:868305.","journal-title":"J Obes"},{"key":"1242_CR17","doi-asserted-by":"publisher","first-page":"1337","DOI":"10.1002\/cphy.c120033","volume":"3","author":"BK Pedersen","year":"2013","unstructured":"Pedersen BK. Muscle as a secretory organ. Compr Physiol. 2013;3:1337\u201362.","journal-title":"Compr Physiol"},{"key":"1242_CR18","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1042\/bse0420105","volume":"42","author":"BK Pedersen","year":"2006","unstructured":"Pedersen BK. The anti-inflammatory effect of exercise: its role in diabetes and cardiovascular disease control. Essays Biochem. 2006;42:105\u201317.","journal-title":"Essays Biochem"},{"key":"1242_CR19","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1007\/s40279-013-0039-8","volume":"43","author":"H Zouhal","year":"2013","unstructured":"Zouhal H, Lemoine-Morel S, Mathieu ME, Casazza GA, Jabbour G. Catecholamines and obesity: effects of exercise and training. Sports Med. 2013;43:591\u2013600.","journal-title":"Sports Med"},{"key":"1242_CR20","doi-asserted-by":"publisher","first-page":"S197","DOI":"10.1139\/apnm-2015-0663","volume":"41","author":"VJ Poitras","year":"2016","unstructured":"Poitras VJ, Gray CE, Borghese MM, Carson V, Chaput JP, Janssen I, et al. Systematic review of the relationships between objectively measured physical activity and health indicators in school-aged children and youth. Appl Physiol Nutr Metab. 2016;41:S197\u2013S239.","journal-title":"Appl Physiol Nutr Metab"},{"key":"1242_CR21","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1136\/bjsm.2008.046391","volume":"44","author":"FB Ortega","year":"2010","unstructured":"Ortega FB, Ruiz JR, Hurtig-Wennlof A, Vicente-Rodriguez G, Rizzo NS, Castillo MJ, et al. Cardiovascular fitness modifies the associations between physical activity and abdominal adiposity in children and adolescents: the European Youth Heart Study. Brit J Sport Med. 2010;44:256\u201362.","journal-title":"Brit J Sport Med"},{"key":"1242_CR22","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1055\/s-0030-1261935","volume":"31","author":"V Espana-Romero","year":"2010","unstructured":"Espana-Romero V, Ortega FB, Ruiz JR, Artero EG, Martinez-Gomez D, Vicente-Rodriguez G, et al. Role of cardiorespiratory fitness on the association between physical activity and abdominal fat content in adolescents: The HELENA Study. Int J Sports Med. 2010;31:679\u201382.","journal-title":"Int J Sports Med"},{"key":"1242_CR23","doi-asserted-by":"publisher","first-page":"1821","DOI":"10.1007\/s40279-017-0716-0","volume":"47","author":"JH Migueles","year":"2017","unstructured":"Migueles JH, Cadenas-Sanchez C, Ekelund U, Delisle Nystrom C, Mora-Gonzalez J, Lof M, et al. Accelerometer data collection and processing criteria to assess physical activity and other outcomes: a systematic review and practical considerations. Sports Med. 2017;47:1821\u201345.","journal-title":"Sports Med"},{"key":"1242_CR24","doi-asserted-by":"publisher","first-page":"2363","DOI":"10.1007\/s40279-017-0753-8","volume":"47","author":"WTB Eddolls","year":"2017","unstructured":"Eddolls WTB, McNarry MA, Stratton G, Winn CON, Mackintosh KA. High-intensity interval training interventions in children and adolescents: a systematic review. Sports Med. 2017;47:2363\u201374.","journal-title":"Sports Med"},{"key":"1242_CR25","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1186\/s40798-018-0154-z","volume":"4","author":"H Collins","year":"2018","unstructured":"Collins H, Fawkner S, Booth JN, Duncan A. The effect of resistance training interventions on weight status in youth: a meta-analysis. Sports Med Open. 2018;4:41.","journal-title":"Sports Med Open"},{"key":"1242_CR26","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1080\/02701367.2017.1294244","volume":"88","author":"R Martin","year":"2017","unstructured":"Martin R, Murtagh EM. Effect of active lessons on physical activity, academic, and health outcomes: a systematic review. Res Q Exerc Sport. 2017;88:149\u201368.","journal-title":"Res Q Exerc Sport"},{"key":"1242_CR27","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1016\/j.jshs.2019.06.006","volume":"10","author":"LK Callender","year":"2021","unstructured":"Callender LK, Borghese MM, Janssen I. Which intensities, types, and patterns of movement behaviors are most strongly associated with cardiometabolic risk factors among children? J Sports Health Sci. 2021;10:368\u201378.","journal-title":"J Sports Health Sci"}],"container-title":["European Journal of Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41430-022-01242-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41430-022-01242-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41430-022-01242-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T07:43:19Z","timestamp":1683704599000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41430-022-01242-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,1]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["1242"],"URL":"https:\/\/doi.org\/10.1038\/s41430-022-01242-y","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-1802844\/v1","asserted-by":"object"}]},"ISSN":["0954-3007","1476-5640"],"issn-type":[{"value":"0954-3007","type":"print"},{"value":"1476-5640","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,1]]},"assertion":[{"value":"28 June 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 November 2022","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 November 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 December 2022","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The research protocol was approved by the Portuguese Ministry of Education and all participants, and their parents or legal guardians provided written informed consent prior to their participation and in accordance with the World Medical Association\u2019s Declaration of Helsinki on human studies.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}}]}}