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This paper presents GN2, a transformer-based flavour tagging algorithm deployed by the ATLAS Collaboration that represents a different methodology compared to previous approaches. Designed to classify jets based on the flavour of their constituent particles, GN2 processes low-level tracking information in an end-to-end architecture and incorporates physics-informed auxiliary training objectives to enhance both interpretability and performance. Its performance is validated in both simulation and collision data. The measured\n                    <jats:italic>c<\/jats:italic>\n                    -jet (light-jet) rejection in data is improved by a factor of 3.5 (1.8) for a 70%\n                    <jats:italic>b<\/jats:italic>\n                    -jet tagging efficiency, compared to the previous algorithm. GN2 provides substantial benefits for physics analyses involving heavy-flavour jets, such as measurements of Higgs boson pair production and the couplings of bottom and charm quarks to the Higgs boson, and demonstrates the impact of advanced machine learning methods in experimental particle physics.\n                  <\/jats:p>","DOI":"10.1038\/s41467-025-65059-6","type":"journal-article","created":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T14:50:36Z","timestamp":1768402236000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Transforming jet flavour tagging at ATLAS"],"prefix":"10.1038","volume":"17","author":[{"name":"The ATLAS Collaboration","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6665-4934","authenticated-orcid":false,"given":"G.","family":"Aad","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7616-1554","authenticated-orcid":false,"given":"E.","family":"Aakvaag","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5888-2734","authenticated-orcid":false,"given":"B.","family":"Abbott","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0287-5869","authenticated-orcid":false,"given":"S.","family":"Abdelhameed","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1002-1652","authenticated-orcid":false,"given":"K.","family":"Abeling","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5763-2760","authenticated-orcid":false,"given":"N. 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