@article{Willett_2022, title={SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway}, volume={7}, ISSN={2058-5276}, url={http://dx.doi.org/10.1038/s41564-022-01143-7}, DOI={10.1038/s41564-022-01143-7}, number={8}, journal={Nature Microbiology}, publisher={Springer Science and Business Media LLC}, author={Willett, Brian J. and Grove, Joe and MacLean, Oscar A. and Wilkie, Craig and De Lorenzo, Giuditta and Furnon, Wilhelm and Cantoni, Diego and Scott, Sam and Logan, Nicola and Ashraf, Shirin and Manali, Maria and Szemiel, Agnieszka and Cowton, Vanessa and Vink, Elen and Harvey, William T. and Davis, Chris and Asamaphan, Patawee and Smollett, Katherine and Tong, Lily and Orton, Richard and Hughes, Joseph and Holland, Poppy and Silva, Vanessa and Pascall, David J. and Puxty, Kathryn and da Silva Filipe, Ana and Yebra, Gonzalo and Shaaban, Sharif and Holden, Matthew T. G. and Pinto, Rute Maria and Gunson, Rory and Templeton, Kate and Murcia, Pablo R. and Patel, Arvind H. and Klenerman, Paul and Dunachie, Susanna and Dunachie, Susanna and Klenerman, Paul and Barnes, Eleanor and Brown, Anthony and Adele, Sandra and Kronsteiner, Barbara and Murray, Sam M. and Abraham, Priyanka and Deeks, Alexandra and Ansari, M. Azim and de Silva, Thushan and Turtle, Lance and Moore, Shona and Austin, James and Richter, Alex and Duncan, Christopher and Payne, Rebecca and Ash, Amy and Koshy, Cherian and Kele, Beatrix and Cutino-Moguel, Teresa and Fairley, Derek J. and McKenna, James P. and Curran, Tanya and Adams, Helen and Fraser, Christophe and Bonsall, David and Fryer, Helen and Lythgoe, Katrina and Thomson, Laura and Golubchik, Tanya and Murray, Abigail and Singleton, Dawn and Beckwith, Shaun M. and Mantzouratou, Anna and Barrow, Magdalena and Buchan, Sarah L. and Reynolds, Nicola and Warne, Ben and Maksimovic, Joshua and Spellman, Karla and McCluggage, Kathryn and John, Michaela and Beer, Robert and Afifi, Safiah and Morgan, Sian and Mack, Andrew and Marchbank, Angela and Price, Anna and Morriss, Arthur and Bresner, Catherine and Kitchen, Christine and Merrick, Ian and Southgate, Joel and Guest, Martyn and Jones, Owen and Munn, Robert and Connor, Thomas R. and Whalley, Thomas and Workman, Trudy and Fuller, William and Patel, Amita and Patel, Bindi and Nebbia, Gaia and Edgeworth, Jonathan and Snell, Luke B. and Batra, Rahul and Charalampous, Themoula and Beckett, Angela H. and Shelest, Ekaterina and Robson, Samuel C. and Underwood, Anthony P. and Taylor, Ben E. W. and Yeats, Corin A. and Aanensen, David M. and Abudahab, Khalil and Menegazzo, Mirko and Joseph, Amelia and Clark, Gemma and Howson-Wells, Hannah C. and Berry, Louise and Khakh, Manjinder and Lister, Michelle M. and Boswell, Tim and Fleming, Vicki M. and Holmes, Christopher W. and McMurray, Claire L. and Shaw, Jessica and Tang, Julian W. and Fallon, Karlie and Odedra, Mina and Willford, Nicholas J. and Bird, Paul W. and Helmer, Thomas and Williams, Lesley-Anne and Sheriff, Nicola and Campbell, Sharon and Raviprakash, Veena and Blakey, Victoria and Moore, Christopher and Sang, Fei and Debebe, Johnny and Carlile, Matthew and Loose, Matthew W. and Holmes, Nadine and Wright, Victoria and Torok, M. Estee and Hamilton, William L. and Carabelli, Alessandro M. and Jermy, Andrew and Blane, Beth and Churcher, Carol M. and Ludden, Catherine and Aggarwal, Dinesh and Westwick, Elaine and Brooks, Ellena and McManus, Georgina M. and Galai, Katerina and Smith, Ken and Smith, Kim S. and Cox, MacGregor and Fragakis, Mireille and Maxwell, Patrick and Judges, Sarah and Peacock, Sharon J. and Feltwell, Theresa and Kenyon, Anita and Eldirdiri, Sahar and Davis, Thomas and Taylor, Joshua F. and Tan, Ngee Keong and Zarebski, Alex E. and Gutierrez, Bernardo and Raghwani, Jayna and du Plessis, Louis and Kraemer, Moritz U. G. and Pybus, Oliver G. and Francois, Sarah and Attwood, Stephen W. and Vasylyeva, Tetyana I. and Jahun, Aminu S. and Goodfellow, Ian G. and Georgana, Iliana and Pinckert, Malte L. and Hosmillo, Myra and Izuagbe, Rhys and Chaudhry, Yasmin and Ryan, Felicity and Lowe, Hannah and Moses, Samuel and Bedford, Luke and Cargill, James S. and Hughes, Warwick and Moore, Jonathan and Stonehouse, Susanne and Shah, Divya and Lee, Jack C. D. and Brown, Julianne R. and Harris, Kathryn A. and Atkinson, Laura and Storey, Nathaniel and Spyer, Moira J. and Flaviani, Flavia and Alcolea-Medina, Adela and Sehmi, Jasveen and Ramble, John and Ohemeng-Kumi, Natasha and Smith, Perminder and Bertolusso, Beatrice and Thomas, Claire and Vernet, Gabrielle and Lynch, Jessica and Moore, Nathan and Cortes, Nicholas and Williams, Rebecca and Kidd, Stephen P. and Levett, Lisa J. and Pusok, Monika and Grant, Paul R. and Kirk, Stuart and Chatterton, Wendy and Xu-McCrae, Li and Smith, Darren L. and Young, Gregory R. and Bashton, Matthew and Kitchman, Katie and Gajee, Kavitha and Eastick, Kirstine and Lillie, Patrick J. and Burns, Phillipa J. and Everson, William and Cox, Alison and Holmes, Alison H. and Bolt, Frances and Price, James R. and Pond, Marcus and Randell, Paul A. and Madona, Pinglawathee and Mookerjee, Siddharth and Volz, Erik M. and Geidelberg, Lily and Ragonnet-Cronin, Manon and Boyd, Olivia and Johnson, Rob and Pope, Cassie F. and Witney, Adam A. and Monahan, Irene M. and Laing, Kenneth G. and Smollett, Katherine L. and McNally, Alan and McMurray, Claire and Stockton, Joanne and Quick, Joshua and Loman, Nicholas J. and Poplawski, Radoslaw and Nicholls, Sam and Rowe, Will and Castigador, Anibolina and Macnaughton, Emily and Bouzidi, Kate El and Sudhanva, Malur and Lampejo, Temi and Martinez Nunez, Rocio T. and Breen, Cassie and Sluga, Graciela and Withell, Karen T. and Machin, Nicholas W. and George, Ryan P. and Ahmad, Shazaad S. Y. and Pritchard, David T. and Binns, Debbie and Wong, Nick and James, Victoria and Williams, Cheryl and Illingworth, Chris J. and Jackson, Chris and de Angelis, Daniela and Pascall, David and Mukaddas, Afrida and Broos, Alice and da Silva Filipe, Ana and Mair, Daniel and Robertson, David L. and Wright, Derek W. and Thomson, Emma C. and Starinskij, Igor and Tsatsani, Ioulia and Shepherd, James G. and Nichols, Jenna and Hughes, Joseph and Nomikou, Kyriaki and Tong, Lily and Orton, Richard J. and Vattipally, Sreenu and Harvey, William T. and Sanderson, Roy and O’Brien, Sarah and Rushton, Steven and Perkins, Jon and Blacow, Rachel and Gunson, Rory N. and Gallagher, Abbie and Wastnedge, Elizabeth and Templeton, Kate E. and McHugh, Martin P. and Dewar, Rebecca and Cotton, Seb and Coupland, Lindsay and Stanley, Rachael and Dervisevic, Samir and Spurgin, Lewis G. and Smith, Louise and Graham, Clive and Padgett, Debra and Barton, Edward and Scott, Garren and Cross, Aidan and Mirfenderesky, Mariyam and Swindells, Emma and Greenaway, Jane and Denton-Smith, Rebecca and Turnbull, Robyn and Idle, Giles and Cole, Kevin and Hollis, Amy and Nelson, Andrew and McCann, Clare M. and Henderson, John H. and Crown, Matthew R. and Yew, Wen C. and Stanley, William and Duckworth, Nichola and Clarke, Phillip and Walsh, Sarah and Sloan, Tim J. and Bicknell, Kelly and Impey, Robert and Wyllie, Sarah and Elliott, Scott and Glaysher, Sharon and Bradley, Declan T. and Killough, Nicholas F. and Wyatt, Tim and Bosworth, Andrew and Vipond, Barry B. and Pearson, Clare and Allara, Elias and Robinson, Esther and Pymont, Hannah M. and Osman, Husam and Muir, Peter and Hopes, Richard and Hutchings, Stephanie and Curran, Martin D. and Parmar, Surendra and Thornton, Alicia and Lackenby, Angie and Bishop, Chloe and Bibby, David and Lee, David and Gallagher, Eileen and Dabrera, Gavin and Harrison, Ian and Hubb, Jonathan and Twohig, Katherine A. and Chand, Meera and Ellaby, Nicholas and Manesis, Nikos and Myers, Richard and Platt, Steven and Mbisa, Tamyo and Chalker, Vicki and Yebra, Gonzalo and Holden, Matthew T. G. and Shaaban, Sharif and Rooke, Stefan and Birchley, Alec and Adams, Alexander and Davies, Alisha and Gaskin, Amy and Gatica-Wilcox, Bree and McKerr, Caoimhe and Moore, Catherine and Williams, Catryn and Williams, Chris and Heyburn, David and De Lacy, Elen and Hilvers, Ember and Downing, Fatima and Pugh, Georgia and Jones, Hannah and Asad, Hibo and Coombes, Jason and Hey, Jessica and Powell, Jessica and Watkins, Joanne and Evans, Johnathan M. and Fina, Laia and Gifford, Laura and Gilbert, Lauren and Graham, Lee and Perry, Malorie and Morgan, Mari and Bull, Matthew and Pacchiarini, Nicole and Craine, Noel and Corden, Sally and Kumziene-Summerhayes, Sara and Rey, Sara and Taylor, Sarah and Cottrell, Simon and Jones, Sophie and Edwards, Sue and Annett, Tara and Trotter, Alexander J. and Mather, Alison E. and Aydin, Alp and Page, Andrew J. and Baker, David J. and Foster-Nyarko, Ebenezer and Kay, Gemma L. and O’Grady, Justin and de Oliveira Martins, Leonardo and Meadows, Lizzie and Alikhan, Nabil-Fareed and Prosolek, Sophie J. and Rudder, Steven and Le-Viet, Thanh and Casey, Anna and Ratcliffe, Liz and Singh, Aditi and Mariappan, Arun and Baxter, Chris and Radulescu, Clara and Simpson, David A. and Lavin, Deborah and Rogan, Fiona and Miskelly, Julia and Fuchs, Marc and Tang, Miao and Carvalho, Sílvia F. and Bridgett, Stephen and Skvortsov, Timofey and Molnar, Zoltan and Ramadan, Newara A. and Knight, Bridget A. and Jones, Christopher R. and Auckland, Cressida and Morcrette, Helen and Poyner, Jennifer and Irish-Tavares, Dianne and Witele, Eric and Hart, Jennifer and Mahungu, Tabitha W. and Haque, Tanzina and Bourgeois, Yann and Fearn, Christopher and Cook, Kate F. and Loveson, Katie F. and Goudarzi, Salman and Evans, Cariad and Partridge, David G. and Johnson, Kate and Yavus, Mehmet and Raza, Mohammad and Mower, Craig and Baker, Paul and Essex, Sarah and Bonner, Stephen and Murray, Leanne J. and Watson, Louisa K. and Liggett, Steven and Lawton, Andrew I. and Lyons, Ronan A. and Payne, Brendan A. I. and Eltringham, Gary and Collins, Jennifer and Waugh, Sheila and Burton-Fanning, Shirelle and Taha, Yusri and Jeanes, Christopher and Gomes, Andrea N. and Murray, Darren R. and Kimuli, Maimuna and Dobie, Donald and Ashfield, Paula and Best, Angus and Percival, Benita and Moles-Garcia, Emma and Ashford, Fiona and Mirza, Jeremy and Crawford, Liam and Mayhew, Megan and Cumley, Nicola and Megram, Oliver and Frampton, Dan and Heaney, Judith and Byott, Matthew and Houlihan, Catherine and Williams, Charlotte A. and Nastouli, Eleni and Lowe, Helen L. and Hartley, John A. and Breuer, Judith and Maftei, Laurentiu and Ensell, Leah and Cotic, Marius and Mondani, Matteo and Driscoll, Megan and Bayzid, Nadua and Williams, Rachel J. and Roy, Sunando and Mahanama, Adhyana I. K. and Samaraweera, Buddhini and Wilson-Davies, Eleri and Pelosi, Emanuela and Umpleby, Helen and Wheeler, Helen and Prieto, Jacqui A. and Saeed, Kordo and Harvey, Matthew and Jeremiah, Sarah and Silviera, Siona and Aplin, Stephen and Sass, Thea and Macklin, Ben and Crudgington, Dorian and Sheridan, Liz A. and Cogger, Benjamin J. and Malone, Cassandra S. and Munemo, Florence and Huckson, Hannah and Lewis, Jonathan and Easton, Lisa J. and Mutingwende, Manasa and Erkiert, Michelle J. and Hassan-Ibrahim, Mohammed O. and Chaloner, Nicola J. and Podplomyk, Olga and Randell, Paul and Nicodemi, Roberto and Lowdon, Sarah and Somassa, Thomas and Richter, Alex and Beggs, Andrew and Hesketh, Andrew R. and Smith, Colin P. and Bucca, Giselda and Ruis, Chris and Cormie, Claire and Higginson, Ellen E. and Young, Jamie and Dias, Joana and Kermack, Leanne M. and Maes, Mailis and Gupta, Ravi K. and Forrest, Sally and Girgis, Sophia T. and Davidson, Rose K. and O’Toole, Áine and Rambaut, Andrew and Jackson, Ben and Balcazar, Carlos E. and Maloney, Daniel and Scher, Emily and McCrone, J. T. and Williamson, Kathleen A. and Gallagher, Michael D. and Medd, Nathan and Colquhoun, Rachel and Stanton, Thomas D. and Williams, Thomas and Hill, Verity and Jeffries, Aaron R. and Temperton, Ben and Sambles, Christine M. and Studholme, David J. and Warwick-Dugdale, Joanna and Jackson, Leigh M. and Michelsen, Michelle L. and Manley, Robin and Michell, Stephen L. and Darby, Alistair C. and Lucaci, Anita O. and Nelson, Charlotte and Wierzbicki, Claudia and Vamos, Edith E. and Webster, Hermione J. and Jackson, Kathryn A. and Rainbow, Lucille and Hughes, Margaret and Whitehead, Mark and Gemmell, Matthew and Iturriza-Gomara, Miren and Eccles, Richard and Gregory, Richard and Haldenby, Sam T. and Paterson, Steve and Angyal, Adrienn and Keeley, Alexander J. and Foulkes, Benjamin H. and Lindsey, Benjamin B. and Wang, Dennis and Hornsby, Hailey R. and Green, Luke R. and Pohare, Manoj and Gallis, Marta and Parker, Matthew D. and Whiteley, Max and Smith, Nikki and Wolverson, Paige and Zhang, Peijun and Hansford, Samantha E. and Hsu, Sharon N. and Louka, Stavroula F. and de Silva, Thushan I. and Freeman, Timothy M. and Mori, Matilde and Park, Emily J. and Hill, Jack D. and Dey, Jayasree and Ball, Jonathan and Chappell, Joseph G. and McClure, Patrick C. and Byaruhanga, Timothy and Fanaie, Arezou and Yaze, Geraldine and Hilson, Rachel A. and Trebes, Amy and Green, Angie and Buck, David and MacIntyre-Cockett, George and Todd, John A. and Bassett, Andrew R. and Whitwham, Andrew and Langford, Cordelia F. and Rajan, Diana and Kwiatkowski, Dominic and Harrison, Ewan M. and Bronner, Iraad F. and Tovar-Corona, Jaime M. and Liddle, Jennifier and Durham, Jillian and Bellis, Katherine L. and Lewis, Kevin and Aigrain, Louise and Redshaw, Nicholas M. and Davies, Robert M. and Moll, Robin J. and McCarthy, Shane A. and Lensing, Stefanie V. and Leonard, Steven and Farr, Ben W. and Scott, Carol and Beaver, Charlotte and Ariani, Cristina V. and Weldon, Danni and Jackson, David K. and Betteridge, Emma and Tonkin-Hill, Gerry and Johnston, Ian and Martincorena, Inigo and Bonfield, James and Barrett, Jeffrey C. and Sillitoe, John and Keatley, Jon-Paul and Oliver, Karen and James, Keith and Shirley, Lesley and Prestwood, Liam and Foulser, Luke and Gourtovaia, Marina and Dorman, Matthew J. and Quail, Michael A. and Spencer Chapman, Michael H. and Park, Naomi R. and Livett, Rich and Amato, Roberto and Kay, Sally and Goodwin, Scott and Thurston, Scott A. J. and Rajatileka, Shavanthi and Gonçalves, Sónia and Lo, Stephanie and Sanderson, Theo and Maclean, Alasdair and Goldstein, Emily J. and Ferguson, Lynne and Tomb, Rachael and Catalan, Jana and Jones, Neil and Haughney, John and Robertson, David L. and Palmarini, Massimo and Ray, Surajit and Thomson, Emma C.}, year={2022}, month=July, pages={1161–1179} }