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The differences in emission intensities of <jats:sup>4<\/jats:sup>I<jats:sub>13\/2<\/jats:sub>\u2009\u2192\u2009<jats:sup>4<\/jats:sup>I<jats:sub>15\/2<\/jats:sub> transition in NIR region when excited with Ar<jats:sup>+<\/jats:sup> and 980\u2009nm lasers were explained in terms of energy transfer mechanisms. Temperature and power dependence of upconversion bands in the visible region centered at 528, 548 and 660\u2009nm pertaining to <jats:sup>2<\/jats:sup>H<jats:sub>11\/2<\/jats:sub>, <jats:sup>4<\/jats:sup>S<jats:sub>3\/2<\/jats:sub> and <jats:sup>4<\/jats:sup>F<jats:sub>9\/2<\/jats:sub>\u2009\u2192\u2009<jats:sup>4<\/jats:sup>I<jats:sub>15\/2<\/jats:sub> transitions were investigated. Fluorescence intensity ratio (FIR) technique was used to explore temperature sensing behaviour of the thermally coupled levels <jats:sup>2<\/jats:sup>H<jats:sub>11\/2<\/jats:sub>\/<jats:sup>4<\/jats:sup>S<jats:sub>3\/2<\/jats:sub> of Er<jats:sup>3+<\/jats:sup> ions in the phosphors within the temperature range 14\u2013300\u2009K and the results were extrapolated up to 600\u2009K. Anomalous intensity trend observed in Er<jats:sup>3+<\/jats:sup> doped SLA phosphor was discussed using energy level structure. Cytotoxicity of phosphors has been evaluated using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay in Bluegill sunfish cells (BF-2). The non-cytotoxic nature and high sensitivity of the present phosphors pay a way for their use <jats:italic>in vitro<\/jats:italic> studies and provide potential interest as a thermo graphic phosphor at the contact of biological products.<\/jats:p>","DOI":"10.1038\/s41598-017-17725-z","type":"journal-article","created":{"date-parts":[[2017,12,11]],"date-time":"2017-12-11T12:09:16Z","timestamp":1512994156000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":66,"title":["Highly efficient upconversion of Er3+ in Yb3+ codoped non-cytotoxic strontium lanthanum aluminate phosphor for low temperature sensors"],"prefix":"10.1038","volume":"7","author":[{"given":"K.","family":"Pavani","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4999-9495","authenticated-orcid":false,"given":"J.","family":"Suresh Kumar","sequence":"additional","affiliation":[]},{"given":"K.","family":"Srikanth","sequence":"additional","affiliation":[]},{"given":"M. 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