{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T14:25:58Z","timestamp":1762352758345,"version":"3.37.3"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T00:00:00Z","timestamp":1551312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T00:00:00Z","timestamp":1551312000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study aims to: (1) to compare 2 methods of assessing the timing of medium latency responses (MLR), in regard to intrasession reliability and mean values, in subjects with and without chronic ankle instability (CAI), and (2) to analyze the influence of CAI in timing of MLR and in its reliability. Thirty six athletes with (16) and without (20) CAI participated. Bilateral electromyography of peroneus longus (PL), peroneus brevis (PB), tibialis anterior (TA) and soleus (SOL) muscles was collected during a unilateral sudden inversion perturbation to assess the timing of MLR onset, in both standing and perturbed positions, through a baseline-based method and a peak-response-based method. The group without CAI presented higher relative reliability of SOL and peroneal muscles MLR with the peak response-based method than with the baseline-based method. Compared with the group without CAI and in both methods, the group with CAI presented a delayed and less reliable TA MLR, as well decreased coefficient variation of PL MLR in the uninjured limb. In conclusion, regardless of the method subjects with CAI present delayed and less reliable TA MLR while in subjects without CAI the peak response-based method provides higher reliability.<\/jats:p>","DOI":"10.1038\/s41598-019-40073-z","type":"journal-article","created":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T11:05:29Z","timestamp":1551351929000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Reliability of two methods for identifying the timing of medium latency responses in subjects with and without chronic ankle instability"],"prefix":"10.1038","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9528-1463","authenticated-orcid":false,"given":"Andreia S. P.","family":"Sousa","sequence":"first","affiliation":[]},{"given":"Isabel","family":"Valente","sequence":"additional","affiliation":[]},{"given":"Ana","family":"Pinto","sequence":"additional","affiliation":[]},{"given":"Rubim","family":"Santos","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2019,2,28]]},"reference":[{"issue":"1","key":"40073_CR1","first-page":"80","volume":"37","author":"BL Riemann","year":"2002","unstructured":"Riemann, B. L. & Lephart, S. M. The Sensorimotor System, Part II: The Role of Proprioception in Motor Control and Functional Joint Stability. J Athl Train. 37(1), 80\u201384 (2002).","journal-title":"J Athl Train."},{"issue":"1","key":"40073_CR2","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1093\/brain\/113.1.65","volume":"113","author":"A Nardone","year":"1990","unstructured":"Nardone, A. et al. Responses of Leg Muscles in Humans Displaced while Standing. Effects of Effects of Types of Perturbation and of Postural Set. Brain. 113(1), 65\u201384, https:\/\/doi.org\/10.1093\/brain\/113.1.65 (1990).","journal-title":"Brain."},{"key":"40073_CR3","doi-asserted-by":"publisher","first-page":"289","DOI":"10.3389\/fnhum.2016.00289","volume":"10","author":"R Ritzmann","year":"2016","unstructured":"Ritzmann, R. et al. Changes in Balance Strategy and Neuromuscular Control during a Fatiguing Balance Task\u2014A Study in Perturbed Unilateral Stance. Frontiers in Human Neuroscience. 10, 289, https:\/\/doi.org\/10.3389\/fnhum.2016.00289 (2016).","journal-title":"Frontiers in Human Neuroscience."},{"issue":"2","key":"40073_CR4","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1152\/japplphysiol.01447.2005","volume":"101","author":"W Taube","year":"2006","unstructured":"Taube, W. et al. Direct corticospinal pathways contribute to neuromuscular control of perturbed stance. Journal of Applied Physiology. 101(2), 420\u2013429, https:\/\/doi.org\/10.1152\/japplphysiol.01447.2005 (2006).","journal-title":"Journal of Applied Physiology."},{"issue":"3","key":"40073_CR5","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1111\/j.1469-7793.2001.00925.x","volume":"534","author":"MJ Grey","year":"2001","unstructured":"Grey, M. J. et al. Group II muscle afferents probably contribute to the medium latency soleus stretch reflex during walking in humans. J. Physiol. 534(3), 925\u2013933 (2001).","journal-title":"J. Physiol."},{"issue":"4","key":"40073_CR6","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1016\/S0149-7634(97)00035-3","volume":"22","author":"V Dietz","year":"1998","unstructured":"Dietz, V. Evidence for a Load Receptor Contribution to the Control of Posture and Locomotion. Neurosci Biobehav Rev. 22(4), 495\u2013499, https:\/\/doi.org\/10.1016\/S0149-7634(97)00035-3 (1998).","journal-title":"Neurosci Biobehav Rev."},{"issue":"Pt 1","key":"40073_CR7","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1113\/jphysiol.2005.087817","volume":"566","author":"V Marchand-Pauvert","year":"2005","unstructured":"Marchand-Pauvert, V. et al. Increase in group II excitation from ankle muscles to thigh motoneurones during human standing. J Physiol. 566(Pt 1), 257\u201371, https:\/\/doi.org\/10.1113\/jphysiol.2005.087817 (2005).","journal-title":"J Physiol."},{"issue":"1","key":"40073_CR8","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1007\/BF00235630","volume":"61","author":"V Dietz","year":"1985","unstructured":"Dietz, V., Quintern, J. & Berger, W. Afferent control of human stance and gait: evidence for blocking of group I afferents during gait. Experimental Brain Research. 61(1), 153\u2013163, https:\/\/doi.org\/10.1007\/BF00235630 (1985).","journal-title":"Experimental Brain Research."},{"issue":"Pt 3","key":"40073_CR9","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1113\/jphysiol.1995.sp020705","volume":"484","author":"S Corna","year":"1995","unstructured":"Corna, S. et al. Selective depression of medium-latency leg and foot muscle responses to stretch by an alpha 2-agonist in humans. Journal of Physiology. 484(Pt 3), 803\u2013809 (1995).","journal-title":"Journal of Physiology."},{"issue":"2\u20133","key":"40073_CR10","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/S0304-3940(96)12430-7","volume":"206","author":"A Nardone","year":"1996","unstructured":"Nardone, A. et al. Different effect of height on latency of leg and foot short- and medium-latency EMG responses to perturbation of stance in humans. Neuroscience Letters. 206(2\u20133), 89\u201392, https:\/\/doi.org\/10.1016\/S0304-3940(96)12430-7 (1996).","journal-title":"Neuroscience Letters."},{"issue":"7","key":"40073_CR11","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1016\/0021-9290(95)00175-1","volume":"29","author":"V Dietz","year":"1996","unstructured":"Dietz, V. Interaction between central programs and afferent input in the control of posture and locomotion. Journal of Biomechanics. 29(7), 841\u20134 (1996).","journal-title":"Journal of Biomechanics."},{"issue":"4","key":"40073_CR12","doi-asserted-by":"publisher","first-page":"360","DOI":"10.4085\/1062-6050-52.2.08","volume":"52","author":"ASP Sousa","year":"2017","unstructured":"Sousa, A. S. P. et al. Bilateral proprioceptive evaluation in individuals with unilateral chronic ankle instability. J Athl Train. 52(4), 360\u2013367 (2017).","journal-title":"J Athl Train."},{"issue":"4","key":"40073_CR13","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1302\/0301-620X.47B4.669","volume":"47","author":"MA Freeman","year":"1965","unstructured":"Freeman, M. A. Instability of the foot after injuries to the lateral ligament of the ankle. J Bone Joint Surg. 47(4), 669\u2013677 (1965).","journal-title":"J Bone Joint Surg."},{"key":"40073_CR14","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.clinbiomech.2018.06.015","volume":"57","author":"ASP Sousa","year":"2018","unstructured":"Sousa, A. S. P. et al. Bilateral compensatory postural adjustments to a unilateral perturbation in subjects with chronic ankle instability. Clin Biomech (Bristol, Avon). 57, 99\u2013106, https:\/\/doi.org\/10.1016\/j.clinbiomech.2018.06.015 (2018).","journal-title":"Clin Biomech (Bristol, Avon)."},{"key":"40073_CR15","doi-asserted-by":"publisher","DOI":"10.4085\/1062-6050-120-17","author":"ASP Sousa","year":"2018","unstructured":"Sousa, A. S. P. et al. Short and Medium Latency Responses in Participants With Chronic Ankle Instability. Journal of Athletic Training. https:\/\/doi.org\/10.4085\/1062-6050-120-17 (2018).","journal-title":"Journal of Athletic Training"},{"issue":"8","key":"40073_CR16","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.1249\/MSS.0b013e31817356b6","volume":"40","author":"A Mitchel","year":"2008","unstructured":"Mitchel, A. et al. Biomechanics of Ankle Instability. Part 1: Reaction Time to Simulated Ankle Sprain. Med Sci Sports Exerc. 40(8), 1515\u20131521, https:\/\/doi.org\/10.1249\/MSS.0b013e31817356b6 (2008).","journal-title":"Med Sci Sports Exerc."},{"issue":"10","key":"40073_CR17","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1007\/s00702-007-0657-0","volume":"114","author":"JV Jacobs","year":"2007","unstructured":"Jacobs, J. V. & Horak, F. B. Cortical control of postural responses. Journal of neural transmission (Vienna, Austria: 1996). 114(10), 1339\u20131348, https:\/\/doi.org\/10.1007\/s00702-007-0657-0 (2007).","journal-title":"Journal of neural transmission (Vienna, Austria: 1996)."},{"issue":"1","key":"40073_CR18","first-page":"67","volume":"2001","author":"G Staude","year":"2001","unstructured":"Staude, G. et al. Onset detection in surface electromyographic signals: a systematic comparison of methods. EURASIP Journal on Applied Signal Processing. 2001(1), 67\u201381 (2001).","journal-title":"EURASIP Journal on Applied Signal Processing."},{"issue":"1","key":"40073_CR19","first-page":"60","volume":"42","author":"C Eechaute","year":"2007","unstructured":"Eechaute, C. et al. Test-Retest Reliability of Sudden Ankle Inversion Measurements in Subjects With Healthy Ankle Joints. Journal of Athletic Training. 42(1), 60\u201365 (2007).","journal-title":"Journal of Athletic Training."},{"issue":"1","key":"40073_CR20","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/S0268-0033(99)00026-1","volume":"15","author":"S Benesch","year":"2000","unstructured":"Benesch, S. et al. Reliability of peroneal reaction time measurements. Clin Biomech (Bristol, Avon). 15(1), 21\u20138 (2000).","journal-title":"Clin Biomech (Bristol, Avon)."},{"issue":"4","key":"40073_CR21","doi-asserted-by":"publisher","first-page":"366","DOI":"10.4085\/1062-6050-46.4.366","volume":"46","author":"SV Deun","year":"2011","unstructured":"Deun, S. V. et al. Stability of Measurement Outcomes for Voluntary Task Performance in Participants With Chronic Ankle Instability and Healthy Participants. Journal of Athletic Training. 46(4), 366\u2013375, https:\/\/doi.org\/10.4085\/1062-6050-46.4.366 (2011).","journal-title":"Journal of Athletic Training."},{"issue":"1","key":"40073_CR22","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.gaitpost.2009.03.006","volume":"30","author":"C Eechaute","year":"2009","unstructured":"Eechaute, C. et al. Reliability and discriminative validity of sudden ankle inversion measurements in patients with chronic ankle instability. Gait & Posture. 30(1), 82\u201386, https:\/\/doi.org\/10.1016\/j.gaitpost.2009.03.006 (2009).","journal-title":"Gait & Posture."},{"issue":"Pt 3","key":"40073_CR23","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1111\/j.1469-7793.1997.691bg.x","volume":"503","author":"M Schieppati","year":"1997","unstructured":"Schieppati, M. & Nardone, A. Medium-latency stretch reflexes of foot and leg muscles analysed by cooling the lower limb in standing humans. Journal of Physiology. 503(Pt 3), 691\u2013698 (1997).","journal-title":"Journal of Physiology."},{"issue":"1","key":"40073_CR24","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1136\/jnnp.50.1.66","volume":"50","author":"E Scholz","year":"1987","unstructured":"Scholz, E. et al. Medium and long latency EMG responses in leg muscles: Parkinson\u2019s disease. Journal of Neurology, Neurosurgery, and Psychiatry. 50(1), 66\u201370 (1987).","journal-title":"Journal of Neurology, Neurosurgery, and Psychiatry."},{"issue":"5","key":"40073_CR25","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1123\/jab.2014-0222","volume":"31","author":"AS Sousa","year":"2015","unstructured":"Sousa, A. S., Silva, A. & Santos, R. Reliability of Two Methods for Identifying the Postural Phase of Gait Initiation in Healthy and Poststroke Subjects. J Appl Biomech. 31(5), 349\u201356, https:\/\/doi.org\/10.1123\/jab.2014-0222 (2015).","journal-title":"J Appl Biomech."},{"issue":"3","key":"40073_CR26","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1007\/s00221-002-1109-6","volume":"145","author":"M Grey","year":"2002","unstructured":"Grey, M., Larsen, B. & Sinkj\u00e6r, T. A task dependent change in the medium latency component of the soleus stretch reflex. Experimental Brain Research. 145(3), 316\u2013322, https:\/\/doi.org\/10.1007\/s00221-002-1109-6 (2002).","journal-title":"Experimental Brain Research."},{"issue":"2","key":"40073_CR27","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1037\/0033-2909.86.2.420","volume":"86","author":"PE Shrout","year":"1979","unstructured":"Shrout, P. E. & Fleiss, J. L. Intraclass correlations: uses in assessing rater reliability. Psychol Bull. 86(2), 420\u20138 (1979).","journal-title":"Psychol Bull."},{"key":"40073_CR28","unstructured":"Streiner, D. L. & Norman, G. R. Health Measurement Scales: A Practical Guide to thieir Development and Use. 2008, Oxford: Oxford University Press."},{"key":"40073_CR29","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1097\/00003086-199805000-00022","volume":"350","author":"D Hopper","year":"1998","unstructured":"Hopper, D. et al. Reliability of the peroneal latency in normal ankles. Clin Orthop Relat Res. 350, 159\u201365 (1998).","journal-title":"Clin Orthop Relat Res."},{"issue":"1","key":"40073_CR30","doi-asserted-by":"publisher","first-page":"121","DOI":"10.4085\/1062-6050-49.1.14","volume":"49","author":"PA Gribble","year":"2014","unstructured":"Gribble, P. A. et al. Selection Criteria for Patients With Chronic Ankle Instability in Controlled Research: A Position Statement of the International Ankle Consortium. J Athl Train. 49(1), 121\u2013127, https:\/\/doi.org\/10.4085\/1062-6050-49.1.14 (2014).","journal-title":"J Athl Train."},{"issue":"2","key":"40073_CR31","first-page":"154","volume":"41","author":"CL Docherty","year":"2006","unstructured":"Docherty, C. L. et al. Development and Reliability of the Ankle Instability Instrument. J Athl Train. 41(2), 154\u2013158 (2006).","journal-title":"J Athl Train."},{"issue":"5","key":"40073_CR32","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/S1050-6411(00)00027-4","volume":"10","author":"HJ Hermens","year":"2000","unstructured":"Hermens, H. J. et al. Development of recommendations for SEMG sensors and sensor placement procedures. J Electromyogr Kinesiol. 10(5), 361\u201374 (2000).","journal-title":"J Electromyogr Kinesiol."},{"issue":"1","key":"40073_CR33","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1007\/BF00248294","volume":"74","author":"E Toft","year":"1989","unstructured":"Toft, E., Sinkjaer, T. & Andreassen, S. Mechanical and electromyographic responses to stretch of the human anterior tibial muscle at different levels of contraction. Experimental Brain Research. 74(1), 213\u2013219 (1989).","journal-title":"Experimental Brain Research."},{"issue":"1","key":"40073_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00221-004-1980-4","volume":"160","author":"B Friemert","year":"2005","unstructured":"Friemert, B. et al. Differentiation of hamstring short latency versus medium latency responses after tibia translation. Experimental Brain Research. 160(1), 1\u20139, https:\/\/doi.org\/10.1007\/s00221-004-1980-4 (2005).","journal-title":"Experimental Brain Research."},{"issue":"4","key":"40073_CR35","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1007\/s00221-008-1647-7","volume":"193","author":"J Schuurmans","year":"2009","unstructured":"Schuurmans, J. et al. The monosynaptic Ia afferent pathway can largely explain the stretch duration effect of the long latency M2 response. Experimental Brain Research. 193(4), 491\u2013500, https:\/\/doi.org\/10.1007\/s00221-008-1647-7 (2009).","journal-title":"Experimental Brain Research."},{"key":"40073_CR36","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/S0304-3940(96)12430-7","volume":"206","author":"A Nardone","year":"1996","unstructured":"Nardone, A. et al. Different effect of height on latency of leg and foot short- and medium- latency EMG responses to perturbation of stance in humans. Neuroscience Letters 206, 89\u201392 (1996).","journal-title":"Neuroscience Letters"},{"key":"40073_CR37","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1016\/j.clinph.2003.11.007","volume":"115","author":"A Nardone","year":"2004","unstructured":"Nardone, A. & Schieppati, M. Group II spindle fibres and afferent control of stance. Clues from diabetic neuropathy. Clinical Neurophysiology 115, 779\u2013789 (2004).","journal-title":"Clinical Neurophysiology"},{"key":"40073_CR38","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/S0304-3940(98)00383-8","volume":"249","author":"A Nardone","year":"1998","unstructured":"Nardone, A. & Schieppati, M. Medium-latency response to muscle stretch in human lower limb: estimation of conduction velocity of group II fibres and central delay. Neuroscience Letters 249, 29\u201332 (1998).","journal-title":"Neuroscience Letters"},{"issue":"1","key":"40073_CR39","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1007\/s00221-002-1041-9","volume":"144","author":"FB Horak","year":"2002","unstructured":"Horak, F. B. & Hlavacka, F. Vestibular stimulation affects medium latency postural muscle responses. Experimental brain research. 144(1), 95\u2013102 (2002).","journal-title":"Experimental brain research."},{"key":"40073_CR40","doi-asserted-by":"crossref","unstructured":"Grey, M. J. et al. Group II muscle afferents probably contribute to the medium latency solues stretch reflex during walking in humans. Journal of Physiology. 925\u2013933 (2001).","DOI":"10.1111\/j.1469-7793.2001.00925.x"},{"key":"40073_CR41","unstructured":"Gutierrez, G. M. Neuromuscular Control in Ankle Instability. ProQuest LLC (2008)."},{"key":"40073_CR42","doi-asserted-by":"crossref","unstructured":"Petersen, N. et al. Evidence that a transcortical pathway contributes to stretch reflexes in the tibialis anterior muscle in man. Journal of Physiology. 267\u2014276 (1998).","DOI":"10.1111\/j.1469-7793.1998.267bf.x"},{"issue":"3","key":"40073_CR43","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1055\/s-2007-1024683","volume":"12","author":"L Konradsen","year":"1991","unstructured":"Konradsen, L. & Ravn, J. B. Prolonged Peroneal Reaction Time in Ankle Instability. Int. J Sports Med. 12. 12(3), 290\u2013292 (1991).","journal-title":"Int. J Sports Med. 12."},{"issue":"1","key":"40073_CR44","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1016\/j.jelekin.2004.06.003","volume":"15","author":"S Mathur","year":"2005","unstructured":"Mathur, S., Eng, J. J. & MacIntyre, D. L. Reliability of surface EMG during sustained contractions of the quadriceps. J Electromyogr Kinesiol. 15(1), 102\u201310, https:\/\/doi.org\/10.1016\/j.jelekin.2004.06.003 (2005).","journal-title":"J Electromyogr Kinesiol."},{"issue":"1","key":"40073_CR45","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1007\/BF00228629","volume":"109","author":"S Corna","year":"1996","unstructured":"Corna, S. et al. Unilateral displacement of lower limb evokes bilateral EMG responses in leg and foot muscles in standing humans. Experimental Brain Research. 109(1), 83\u201391, https:\/\/doi.org\/10.1007\/BF00228629 (1996).","journal-title":"Experimental Brain Research."},{"issue":"Pt 3","key":"40073_CR46","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1113\/jphysiol.2002.036244","volume":"550","author":"C Gr\u00fcneberg","year":"2003","unstructured":"Gr\u00fcneberg, C., Nieuwenhuijzen, P. H. J. A. & Duysens, J. Reflex Responses in the Lower Leg following Landing Impact on an Inverting and Non-Inverting Platform. The Journal of Physiology. 550(Pt 3), 985\u2013993, https:\/\/doi.org\/10.1113\/jphysiol.2002.036244 (2003).","journal-title":"The Journal of Physiology."},{"issue":"3","key":"40073_CR47","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1177\/036354659602400319","volume":"24","author":"SA Lynch","year":"1996","unstructured":"Lynch, S. A. et al. Electromyographic latency changes in the ankle musculature during inversion moments. The American journal of sports medicine. 24(3), 362\u2013369 (1996).","journal-title":"The American journal of sports medicine."},{"key":"40073_CR48","unstructured":"Nunnaly, J. C. Psychometric Theory. 2nd ed. 1978, New York: McGraw-Hill."},{"issue":"4","key":"40073_CR49","doi-asserted-by":"publisher","first-page":"217","DOI":"10.2165\/00007256-199826040-00002","volume":"26","author":"G Atkinson","year":"1998","unstructured":"Atkinson, G. & Nevill, A. M. Statistical methods for assessing measurement error (reliability) in variables relevant to sports medicine. Sports medicine. 26(4), 217\u2013238 (1998).","journal-title":"Sports medicine."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-019-40073-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-019-40073-z","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-019-40073-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,17]],"date-time":"2022-12-17T06:39:22Z","timestamp":1671259162000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-019-40073-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,28]]},"references-count":49,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019,12]]}},"alternative-id":["40073"],"URL":"https:\/\/doi.org\/10.1038\/s41598-019-40073-z","relation":{},"ISSN":["2045-2322"],"issn-type":[{"type":"electronic","value":"2045-2322"}],"subject":[],"published":{"date-parts":[[2019,2,28]]},"assertion":[{"value":"4 September 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 January 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 February 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}],"article-number":"3115"}}