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We used cross-sectional\u00a0data of 2618 adults from the Chilean National Health Survey 2016\u20132017. Meeting the 24-h movement guidelines was defined as\u2009\u2265\u2009600 MET-min\/week of physical activity;\u2009\u2264\u20098\u00a0h\/day of sitting time; and 7 to 9\u00a0h\/day of sleep duration. Cardiometabolic health indicators were body mass index, waist circumference, high triglycerides, high blood pressure, type 2 diabetes, metabolic syndrome, and risk of cardiovascular disease\u00a0in a 10-year period. Meeting none out of three 24-h movement guidelines (vs all three) was associated with higher odds of overweight\/obesity (OR 1.67; 95%CI 1.45\u00a0to 1.89), high waist circumference (1.65; 1.40\u00a0to 1.90), hypertension (2.88; 2.23\u00a0to 3.53), type 2 diabetes (1.60; 1.26\u00a0to 1.94), metabolic syndrome (1.97; 1.54\u00a0to 2.40) and risk of cardiovascular disease (1.50; 1.20, 1.80). 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