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Outside of this submitted work, FS received lecture or adboard fees from Chiesi, AZ, GSK, and Novartis. Outside this submitted work, JB reports personal fees (member of advisory boards, consultations, honoraria for meeting lectures) from Cipla, Menarini, Mylan, Novartis, Purina, Sanofi\u2010Aventis, Teva, Uriach. Shareholder of KYomed Innov and MASK-air-SAS. The rest of the authors declare that they have no relevant conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The Study was approved by the CHU Li\u00e8ge ethics committee. Signed informed consent was obtained from patients as soon as they entered the asthma clinic of the CHU Li\u00e8ge. They agreed that their clinical data and the health outcomes they reported in the routine setting would be used for the purposes of research.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}}],"article-number":"29997"}}