{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T18:45:08Z","timestamp":1791917108773,"version":"4.3.4"},"reference-count":44,"publisher":"Royal Society of Chemistry (RSC)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lab Chip"],"published-print":{"date-parts":[[2005]]},"DOI":"10.1039\/b414457k","type":"journal-article","created":{"date-parts":[[2005,1,30]],"date-time":"2005-01-30T11:22:56Z","timestamp":1107084176000},"page":"437","source":"Crossref","is-referenced-by-count":142,"title":["Highly sensitive signal detection of duplex dye-labelled DNA oligonucleotides in a PDMS microfluidic chip: confocal surface-enhanced Raman spectroscopic study"],"prefix":"10.1039","volume":"5","author":[{"given":"Taehan","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sangyeop","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gi Hun","family":"Seong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaebum","family":"Choo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Kyu","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang S.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won Ho","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Yong","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dae-Gab","family":"Gweon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanghoon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","reference":[{"key":"b414457k-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3563","DOI":"10.1002\/elps.200305584","volume":"24","author":"Samuel","year":"2003","journal-title":"Electrophoresis"},{"key":"b414457k-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1126\/science.1073562","volume":"296","author":"Burns","year":"2002","journal-title":"Science"},{"key":"b414457k-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1126\/science.297.5584.1197","volume":"297","author":"Meldrum","year":"2002","journal-title":"Science"},{"key":"b414457k-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1038\/90754","volume":"19","author":"Mitchell","year":"2001","journal-title":"Nat. Biotechnol."},{"key":"b414457k-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1021\/ac015640e","volume":"74","author":"Schilling","year":"2002","journal-title":"Anal. Chem."},{"key":"b414457k-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2623","DOI":"10.1021\/ac0202435","volume":"74","author":"Reyes","year":"2002","journal-title":"Anal. Chem."},{"key":"b414457k-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2637","DOI":"10.1021\/ac020239t","volume":"74","author":"Auroux","year":"2002","journal-title":"Anal. Chem."},{"key":"b414457k-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"330A","DOI":"10.1021\/ac002800y","volume":"72","author":"Flgeys","year":"2000","journal-title":"Anal. Chem."},{"key":"b414457k-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1146\/annurev.bioeng.4.112601.125916","volume":"4","author":"Beebe","year":"2002","journal-title":"Annu. Rev. Biomed. Eng."},{"key":"b414457k-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1126\/science.1076996","volume":"298","author":"Thorsen","year":"2002","journal-title":"Science"},{"key":"b414457k-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2957","DOI":"10.1021\/cr980133r","volume":"99","author":"Kneipp","year":"1999","journal-title":"Chem. Rev."},{"key":"b414457k-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1126\/science.275.5303.1102","volume":"275","author":"Nie","year":"1997","journal-title":"Science"},{"key":"b414457k-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6196","DOI":"10.1021\/ac0346003","volume":"75","author":"Chulha","year":"2003","journal-title":"Anal. Chem."},{"key":"b414457k-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1021\/ac035134k","volume":"76","author":"Yonzon","year":"2004","journal-title":"Anal. Chem."},{"key":"b414457k-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1002\/jrs.1038","volume":"34","author":"Lee","year":"2003","journal-title":"J. Raman Spectrosc."},{"key":"b414457k-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8009","DOI":"10.1021\/ja9815677","volume":"120","author":"Emory","year":"1998","journal-title":"J. Am. Chem. Soc."},{"key":"b414457k-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1021\/jp9734033","volume":"102","author":"Emory","year":"1998","journal-title":"J. Phys. Chem. B"},{"key":"b414457k-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9208","DOI":"10.1021\/ja992058n","volume":"121","author":"Krugg, II","year":"1999","journal-title":"J. Am. Chem. Soc."},{"key":"b414457k-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1002\/adma.200305149","volume":"15","author":"Chan","year":"2003","journal-title":"Adv. Mater."},{"key":"b414457k-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6171","DOI":"10.1021\/ac034672u","volume":"75","author":"Doering","year":"2003","journal-title":"Anal. Chem."},{"key":"b414457k-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4784","DOI":"10.1021\/la026706j","volume":"19","author":"Mulvancy","year":"2003","journal-title":"Langmuir"},{"key":"b414457k-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1039\/b302409a","volume":"128","author":"Jana","year":"2003","journal-title":"Analyst"},{"key":"b414457k-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1039\/b311589e","author":"Docherty","year":"2004","journal-title":"Chem. Commun."},{"key":"b414457k-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/0003-2670(93)85274-N","volume":"283","author":"Laserna","year":"1993","journal-title":"Anal. Chim. Acta"},{"key":"b414457k-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1366\/0003702904087217","volume":"44","author":"Taylor","year":"1990","journal-title":"Appl. Spectrosc."},{"key":"b414457k-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0003-2670(95)00441-6","volume":"318","author":"Cabalin","year":"1996","journal-title":"Anal. Chim. Acta"},{"key":"b414457k-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4455","DOI":"10.1021\/ac990576a","volume":"71","author":"Jacobson","year":"1999","journal-title":"Anal. Chem."},{"key":"b414457k-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1126\/science.1066238","volume":"295","author":"Stroock","year":"2002","journal-title":"Science"},{"key":"b414457k-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1942","DOI":"10.1021\/ac000850x","volume":"73","author":"He","year":"2001","journal-title":"Anal. Chem."},{"key":"b414457k-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1073\/pnas.91.5.1927","volume":"91","author":"Foster","year":"1994","journal-title":"Proc. Natl. Acad. Sci."},{"key":"b414457k-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/372525a0","volume":"372","author":"Foster","year":"1994","journal-title":"Nature"},{"key":"b414457k-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1136\/jmg.33.6.465","volume":"33","author":"Kwok","year":"1996","journal-title":"J. Med. Genet."},{"key":"b414457k-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1039\/B105110P","volume":"1","author":"Hofmann","year":"2001","journal-title":"Lab Chip"},{"key":"b414457k-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3461","DOI":"10.1002\/1522-2683(200210)23:20<3461::AID-ELPS3461>3.0.CO;2-8","volume":"23","author":"Ng","year":"2002","journal-title":"Electrophoresis"},{"key":"b414457k-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1002\/(SICI)1522-2683(20000101)21:1<27::AID-ELPS27>3.0.CO;2-C","volume":"21","author":"McDonald","year":"2000","journal-title":"Electrophoresis"},{"key":"b414457k-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1021\/ac010895d","volume":"74","author":"Johnson","year":"2002","journal-title":"Anal. Chem."},{"key":"b414457k-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5723","DOI":"10.1021\/jp027460u","volume":"107","author":"Leopold","year":"2003","journal-title":"J. Phys. Chem. B"},{"key":"b414457k-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1002\/(SICI)1521-3773(20000317)39:6<1061::AID-ANIE1061>3.0.CO;2-9","volume":"39","author":"Graham","year":"2000","journal-title":"Angew. Chem. Int. Ed. Engl."},{"key":"b414457k-(cit39)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4703","DOI":"10.1021\/ac970657b","volume":"69","author":"Graham","year":"1997","journal-title":"Anal. Chem."},{"key":"b414457k-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1021\/ac0155456","volume":"74","author":"Graham","year":"2002","journal-title":"Anal. Chem."},{"key":"b414457k-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1021\/ac980386k","volume":"71","author":"Jones","year":"1999","journal-title":"Anal. Chem."},{"key":"b414457k-(cit42)\/*[position()=1]","first-page":"85","volume":"57","author":"Graham","year":"2000","journal-title":"Biospectroscopy"},{"key":"b414457k-(cit43)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1109\/84.846699","volume":"9","author":"Liu","year":"2000","journal-title":"J. Microelectromech. Syst."},{"key":"b414457k-(cit44)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1021\/ac035060c","volume":"76","author":"Faulds","year":"2004","journal-title":"Anal. Chem."}],"container-title":["Lab on a Chip"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2005\/LC\/B414457K","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T20:15:40Z","timestamp":1782850540000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/lc\/article\/5\/4\/437-442\/196442"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":44,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005]]}},"URL":"https:\/\/doi.org\/10.1039\/b414457k","relation":{},"ISSN":["1473-0197","1473-0189"],"issn-type":[{"value":"1473-0197","type":"print"},{"value":"1473-0189","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005]]}}}