{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:18:41Z","timestamp":1782883121204,"version":"3.54.5"},"reference-count":63,"publisher":"Royal Society of Chemistry (RSC)","issue":"21","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Org. Biomol. Chem."],"published-print":{"date-parts":[[2005]]},"DOI":"10.1039\/b510098d","type":"journal-article","created":{"date-parts":[[2005,9,20]],"date-time":"2005-09-20T06:23:08Z","timestamp":1127197388000},"page":"3843","source":"Crossref","is-referenced-by-count":39,"title":["Directing the secondary structure of polypeptides at will: from helices to amyloids and back again?"],"prefix":"10.1039","volume":"3","author":[{"given":"Kevin","family":"Pagel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toni","family":"Vagt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beate","family":"Koksch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","reference":[{"key":"b510098d-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1038\/nature02264","volume":"426","author":"Selkoe","year":"2003","journal-title":"Nature"},{"key":"b510098d-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/nrn1007","volume":"4","author":"Soto","year":"2003","journal-title":"Nat. Rev. Neurosci."},{"key":"b510098d-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1126\/science.273.5281.1492","volume":"271","author":"Taube","year":"1996","journal-title":"Science"},{"key":"b510098d-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0959-440X(96)80089-3","volume":"6","author":"Kelly","year":"1996","journal-title":"Curr. Opin. Struct. Biol."},{"key":"b510098d-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/s001090050371","volume":"77","author":"Soto","year":"1999","journal-title":"J. Mol. Med."},{"key":"b510098d-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/S0014-5793(01)02486-3","volume":"498","author":"Soto","year":"2001","journal-title":"FEBS Lett."},{"key":"b510098d-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1126\/science.1067122","volume":"296","author":"Taylor","year":"2002","journal-title":"Science"},{"key":"b510098d-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"35317","DOI":"10.1074\/jbc.M303547200","volume":"278","author":"Schmechel","year":"2003","journal-title":"J. Biol. Chem."},{"key":"b510098d-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1038\/nature02261","volume":"426","author":"Dobson","year":"2003","journal-title":"Nature"},{"key":"b510098d-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1002\/ange.19911031118","volume":"103, 11","author":"Mutter","year":"1991","journal-title":"Angew. Chem."},{"key":"b510098d-(cit10)\/*[position()=2]","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1002\/anie.199115141","volume":"30","author":"Mutter","year":"1991","journal-title":"Angew. Chem. Int. Ed. Engl."},{"key":"b510098d-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2475","DOI":"10.1002\/(SICI)1521-3765(19981204)4:12<2475::AID-CHEM2475>3.0.CO;2-N","volume":"4","author":"Takahashi","year":"1998","journal-title":"Chem. Eur. J."},{"key":"b510098d-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0968-0896(98)00236-3","volume":"7","author":"Takahashi","year":"1999","journal-title":"Bioorg. Med. Chem."},{"key":"b510098d-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4051","DOI":"10.1016\/j.bmcl.2003.08.077","volume":"13","author":"Yamashita","year":"2003","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"b510098d-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4435","DOI":"10.1073\/pnas.0306786101","volume":"101","author":"Kaemmerer","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"b510098d-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"12487","DOI":"10.1021\/ja962026p","volume":"118","author":"Schenck","year":"1996","journal-title":"J. Am. Chem. Soc."},{"key":"b510098d-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"10150","DOI":"10.1074\/jbc.M107663200","volume":"277","author":"Ciani","year":"2002","journal-title":"J. Biol. Chem."},{"key":"b510098d-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4172","DOI":"10.1002\/anie.200454045","volume":"43","author":"Mutter","year":"2004","journal-title":"Angew. Chem., Int. Ed."},{"key":"b510098d-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"041911","DOI":"10.1103\/PhysRevE.68.041911","volume":"68","author":"Peng","year":"2003","journal-title":"Phys. Rev. E"},{"key":"b510098d-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/S0962-8924(00)01898-5","volume":"2","author":"Burkhard","year":"2001","journal-title":"Trends Cell Biol."},{"key":"b510098d-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1002\/pro.5560060606","volume":"6","author":"Wolf","year":"1997","journal-title":"Protein Sci."},{"key":"b510098d-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1002\/cbic.200300781","volume":"5","author":"Mason","year":"2004","journal-title":"ChemBioChem"},{"key":"b510098d-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/S0169-409X(02)00058-3","volume":"54","author":"Yu","year":"2002","journal-title":"Adv. Drug Deliv. Rev."},{"key":"b510098d-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1002\/cbic.200300781","volume":"5","author":"Mason","year":"2004","journal-title":"Chem. Bio. Chem."},{"key":"b510098d-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1006\/jmbi.2000.3866","volume":"300","author":"Tripet","year":"2000","journal-title":"J. Mol. Biol."},{"key":"b510098d-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"12603","DOI":"10.1021\/bi981269m","volume":"37","author":"Oakley","year":"1998","journal-title":"Biochem."},{"key":"b510098d-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1039\/b418167k","volume":"3","author":"Pagel","year":"2005","journal-title":"Org. Biomol. Chem."},{"key":"b510098d-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3862","DOI":"10.1021\/bi00179a010","volume":"33","author":"Monera","year":"1994","journal-title":"Biochem."},{"issue":"26","key":"b510098d-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"19218","DOI":"10.1016\/S0021-9258(19)36502-0","volume":"268","author":"Monera","year":"1993","journal-title":"J. Biol. Chem."},{"key":"b510098d-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1006\/jmbi.2001.5044","volume":"313","author":"McClain","year":"2001","journal-title":"J. Mol. Biol."},{"key":"b510098d-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/S0959-440X(00)00232-3","volume":"11","author":"Oakley","year":"2001","journal-title":"Curr. Opin. Struct. Biol."},{"key":"b510098d-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/S0022-2836(02)00114-6","volume":"318","author":"Burkhard","year":"2002","journal-title":"J. Mol. Biol."},{"key":"b510098d-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S0959-440X(99)80069-4","volume":"9","author":"Lacroix","year":"1999","journal-title":"Curr. Opin. Struct. Biol."},{"key":"b510098d-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1039\/a902466b","volume":"11","author":"Das","year":"1999","journal-title":"Chem. Commun."},{"key":"b510098d-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1039\/b008074h","author":"Searle","year":"2001","journal-title":"J. Chem. Soc., Perkin Trans. 2"},{"key":"b510098d-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.sbi.2004.06.001","volume":"14","author":"Searle","year":"2004","journal-title":"Curr. Opin. Struct. Biol."},{"key":"b510098d-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8747","DOI":"10.1073\/pnas.91.19.8747","volume":"91","author":"Quinn","year":"1994","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"b510098d-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1002\/pro.5560030709","volume":"3","author":"Yan","year":"1994","journal-title":"Protein Sci."},{"key":"b510098d-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1126\/science.281.5374.253","volume":"281","author":"Kortemme","year":"1998","journal-title":"Science"},{"key":"b510098d-(cit39)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1038\/nsb0298-115","volume":"5","author":"Pham","year":"1998","journal-title":"Nat. Struct. Biol."},{"key":"b510098d-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1038\/35000255","volume":"403","author":"Koide","year":"2000","journal-title":"Nature"},{"key":"b510098d-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1021\/bi00699a002","volume":"13","author":"Chou","year":"1974","journal-title":"Biochemistry"},{"key":"b510098d-(cit42)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1096\/fasebj.10.1.8566551","volume":"10","author":"Pace","year":"1996","journal-title":"FASEB J."},{"key":"b510098d-(cit43)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1110\/ps.03429104","volume":"13","author":"Kilosanidze","year":"2004","journal-title":"Protein Sci."},{"key":"b510098d-(cit44)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5682","DOI":"10.1093\/emboj\/cdf573","volume":"21","author":"F\u00e4ndrich","year":"2002","journal-title":"EMBO J."},{"key":"b510098d-(cit45)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7391","DOI":"10.1021\/bi011772q","volume":"41","author":"Chen","year":"2002","journal-title":"Biochemistry"},{"key":"b510098d-(cit46)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1038\/nature02261","volume":"426","author":"Dobson","year":"2003","journal-title":"Nature"},{"key":"b510098d-(cit47)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"10842","DOI":"10.1074\/jbc.M212540200","volume":"278","author":"Kim","year":"2003","journal-title":"J. Biol. Chem."},{"key":"b510098d-(cit48)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5892","DOI":"10.1074\/jbc.M404751200","volume":"280","author":"Yang","year":"2005","journal-title":"J. Biol. Chem."},{"key":"b510098d-(cit49)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/0014-5793(94)80467-2","volume":"341","author":"Camilleri","year":"1994","journal-title":"FEBS Lett"},{"key":"b510098d-(cit50)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1055\/s-2003-37493","volume":"111","author":"Thomas","year":"2003","journal-title":"Exp. Clin. Endocrinol. Diabetes"},{"key":"b510098d-(cit51)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"47497","DOI":"10.1074\/jbc.M405914200","volume":"279","author":"Rzepecki","year":"2004","journal-title":"J. Biol. Chem."},{"key":"b510098d-(cit52)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"13568","DOI":"10.1021\/bi9617264","volume":"35","author":"Salomon","year":"1996","journal-title":"Biochemistry"},{"key":"b510098d-(cit53)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1021\/bi035728h","volume":"43","author":"Moor","year":"2004","journal-title":"Biochemistry"},{"key":"b510098d-(cit54)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8545","DOI":"10.1074\/jbc.271.15.8545","volume":"271","author":"Tjernberg","year":"1996","journal-title":"J. Biol. Chem."},{"key":"b510098d-(cit55)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1038\/nm0798-822","volume":"4","author":"Soto","year":"1998","journal-title":"Nat. Med."},{"key":"b510098d-(cit56)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4041","DOI":"10.1002\/anie.200353565","volume":"43","author":"Gilead","year":"2004","journal-title":"Angew. Chem. Int. Ed."},{"key":"b510098d-(cit57)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"25109","DOI":"10.1074\/jbc.M003554200","volume":"275","author":"Hughes","year":"2000","journal-title":"J. Biol. Chem."},{"key":"b510098d-(cit58)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8237","DOI":"10.1021\/bi002416v","volume":"40","author":"Gordon","year":"2001","journal-title":"Biochemistry"},{"key":"b510098d-(cit60)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S1367-5931(99)00073-3","volume":"4","author":"Bush","year":"2000","journal-title":"Curr. Opin. Chem. Biol."},{"key":"b510098d-(cit61)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/9030","volume":"1","author":"Wadsworth","year":"1999","journal-title":"Nat. Cell Biol."},{"key":"b510098d-(cit62)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2500","DOI":"10.1039\/b505979h","volume":"3","author":"Pagel","year":"2005","journal-title":"Org. Biomol. Chem."},{"key":"b510098d-(cit63)\/*[position()=1]","doi-asserted-by":"publisher","DOI":"10.1529\/biophysj.104.055590","author":"Pineiro","year":"2005","journal-title":"Biophys. J."}],"container-title":["Organic &amp; Biomolecular Chemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2005\/OB\/B510098D","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T04:09:53Z","timestamp":1782878993000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/ob\/article\/3\/21\/3843-3850\/161156"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":63,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2005]]}},"URL":"https:\/\/doi.org\/10.1039\/b510098d","relation":{},"ISSN":["1477-0520","1477-0539"],"issn-type":[{"value":"1477-0520","type":"print"},{"value":"1477-0539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005]]}}}