{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T05:46:48Z","timestamp":1781070408836,"version":"3.54.1"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Photochem Photobiol Sci"],"published-print":{"date-parts":[[2008,11]]},"DOI":"10.1039\/b808776h","type":"journal-article","created":{"date-parts":[[2008,10,29]],"date-time":"2008-10-29T10:48:31Z","timestamp":1225277311000},"page":"1422-1425","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["In vivo nonlinear spectral imagingmicroscopy of visible and ultraviolet irradiated hairless mouse skin tissues"],"prefix":"10.1007","volume":"7","author":[{"given":"Jonathan A.","family":"Palero","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henri\u00ebtte S.","family":"de Bruijn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ang\u00e9lique","family":"van der Ploeg van den Heuvel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henricus J. C. M.","family":"Sterenborg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huib","family":"van Weelden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans C.","family":"Gerritsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,11,1]]},"reference":[{"key":"7011017_CR1","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1034\/j.1600-0781.2001.017002066.x","volume":"17","author":"D W Edstrom","year":"2001","unstructured":"D. W. Edstrom, A. Porwit and A. M. Ros, Effects on human skin of repetitive ultraviolet-A1 (UVA1) irradiation and visible light, Photodermatol. Photoimmunol. Photomed., 2001, 17, 66\u201370.","journal-title":"Photodermatol. Photoimmunol. Photomed."},{"key":"7011017_CR2","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1111\/j.1751-1097.2007.00286.x","volume":"84","author":"B H Mahmoud","year":"2008","unstructured":"B. H. Mahmoud, C. L. Hexsel, I. H. Hamzavi and H. W. Lim, Effects of visible light on the skin, Photochem. Photobiol., 2008, 84, 450\u2013462.","journal-title":"Photochem. Photobiol."},{"key":"7011017_CR3","doi-asserted-by":"publisher","first-page":"6255","DOI":"10.1073\/pnas.96.11.6255","volume":"96","author":"P E Hockberger","year":"1999","unstructured":"P. E. Hockberger, T. A. Skimina, V. E. Centonze, C. Lavin, S. Chu, S. Dadras, J. K. Reddy and J. G. White, Activation of flavin-containing oxidases underlies light-induced production of H2O2 in mammalian cells, Proc. Natl. Acad. Sci. USA, 1999, 96, 6255\u20136260.","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"7011017_CR4","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/S1011-1344(01)00209-3","volume":"63","author":"A M Edwards","year":"2001","unstructured":"A. M. Edwards and E. Silva, Effect of visible light on selected enzymes, vitamins and amino acids, J. Photochem. Photobiol., B, 2001, 63, 126\u2013131.","journal-title":"J. Photochem. Photobiol., B"},{"key":"7011017_CR5","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1002\/lsm.20239","volume":"37","author":"M Eichler","year":"2005","unstructured":"M. Eichler, R. Lavi, A. Shainberg and R. Lubart, Flavins are source of visible-light-induced free radical formation in cells, Lasers Surg. Med., 2005, 37, 314\u2013319.","journal-title":"Lasers Surg. Med."},{"key":"7011017_CR6","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/0748-5514(85)90150-3","volume":"1","author":"M L Cunningham","year":"1985","unstructured":"M. L. Cunningham, N. I. Krinsky, S. M. Giovanazzi and M. J. Peak, Superoxide anion is generated from cellular metabolites by solar radiation and its components, J. Free Radical Biol. Med., 1985, 1, 381\u2013385.","journal-title":"J. Free Radical Biol. Med."},{"key":"7011017_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S1011-1344(98)00219-X","volume":"49","author":"T Karu","year":"1999","unstructured":"T. Karu, Primary and secondary mechanisms of action of visible to near-IR radiation on cells, J. Photochem. Photobiol., B, 1999, 49, 1\u201317.","journal-title":"J. Photochem. Photobiol., B"},{"key":"7011017_CR8","doi-asserted-by":"publisher","first-page":"21061","DOI":"10.1074\/jbc.M502194200","volume":"280","author":"B F Godley","year":"2005","unstructured":"B. F. Godley, F. A. Shamsi, F. Q. Liang, S. G. Jarrett, S. Davies and M. Boulton, Blue light induces mitochondrial DNA damage and free radical production in epithelial cells, J. Biol. Chem., 2005, 280, 21061\u201321066.","journal-title":"J. Biol. Chem."},{"key":"7011017_CR9","doi-asserted-by":"publisher","first-page":"044019","DOI":"10.1117\/1.2953180","volume":"13","author":"J A Palero","year":"2008","unstructured":"J. A. Palero, G. Latouche, H. S. de Bruijn, A. v. d. P. van den Heuvel, H. J. C. M. Sterenborg and H. C. Gerritsen, Design and implementation of a sensitive high-resolution nonlinear spectral imaging microscope, J. Biomed. Opt., 2008, 13, 044019\u2013044011.","journal-title":"J. Biomed. Opt."},{"key":"7011017_CR10","doi-asserted-by":"publisher","first-page":"4395","DOI":"10.1364\/OE.14.004395","volume":"14","author":"J A Palero","year":"2006","unstructured":"J. A. Palero, H. S. de Bruijn, A. van der Ploeg-van den Heuvel, H. J. C. M. Sterenborg and H. C. Gerritsen, In vivo nonlinear spectral imaging in mouse skin, Opt. Express, 2006, 14, 4395\u20134402.","journal-title":"Opt. Express"},{"key":"7011017_CR11","doi-asserted-by":"publisher","first-page":"992","DOI":"10.1529\/biophysj.106.099457","volume":"93","author":"J A Palero","year":"2007","unstructured":"J. A. Palero, H. S. de Bruijn, A. van der Ploeg van den Heuvel, H. J. Sterenborg and H. C. Gerritsen, Spectrally resolved multiphoton imaging of in vivo and excised mouse skin tissues, Biophys. J., 2007, 93, 992\u20131007.","journal-title":"Biophys. J."},{"key":"7011017_CR12","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1088\/1367-2630\/9\/7\/212","volume":"9","author":"J Chen","year":"2007","unstructured":"J. Chen, S. Zhuo, R. Chen, X. Jiang, S. Xie and Q. Zou, Depth-resolved spectral imaging of rabbit oesophageal tissue based on two-photon excited fluorescence and second-harmonic generation, New J. Phys., 2007, 9, 212.","journal-title":"New J. Phys."},{"key":"7011017_CR13","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1007\/s10895-005-0212-z","volume":"15","author":"C Buehler","year":"2005","unstructured":"C. Buehler, K. H. Kim, U. Greuter, N. Schlumpf and P. T. C. So, Single-Photon Counting Multicolor Multiphoton Fluorescence Microscope, J. Fluoresc., 2005, 15, 41\u201351.","journal-title":"J. Fluoresc."},{"key":"7011017_CR14","doi-asserted-by":"publisher","first-page":"2405","DOI":"10.1016\/S0006-3495(97)78886-6","volume":"72","author":"B R Masters","year":"1997","unstructured":"B. R. Masters, P. T. C. So and E. Gratton, Multiphoton excitation fluorescence microscopy and spectroscopy of in vivo human skin, Biophys. J., 1997, 72, 2405\u20132412.","journal-title":"Biophys. J."},{"key":"7011017_CR15","doi-asserted-by":"publisher","first-page":"874","DOI":"10.1111\/j.1365-2133.2007.08108.x","volume":"157","author":"M Yaar","year":"2007","unstructured":"M. Yaar and B. A. Gilchrest, Photoageing: mechanism, prevention and therapy, Br. J. Dermatol., 2007, 157, 874\u2013887.","journal-title":"Br. J. Dermatol."},{"key":"7011017_CR16","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1111\/j.1749-6632.1988.tb18809.x","volume":"548","author":"M R Pittelkow","year":"1988","unstructured":"M. R. Pittelkow, R. J. Coffey, Jr. and H. J. Moses, Keratinocytes produce and are regulated by transforming growth factors, Ann N. Y. Acad. Sci., 1988, 548, 211\u2013224.","journal-title":"Ann N. Y. Acad. Sci."},{"key":"7011017_CR17","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1016\/S0092-8674(00)80303-7","volume":"89","author":"H Hayashi","year":"1997","unstructured":"H. Hayashi, S. Abdollah, Y. Qiu, J. Cai, Y. Y. Xu, B. W. Grinnell, M. A. Richardson, J. N. Topper, M. A. Gimbrone, Jr., J. L. Wrana and D. Falb, The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling, Cell, 1997, 89, 1165\u20131173.","journal-title":"Cell"},{"key":"7011017_CR18","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1046\/j.1523-1747.2000.00091.x","volume":"115","author":"R Gillies","year":"2000","unstructured":"R. Gillies, G. Zonios, R. R. Anderson and N. Kollias, Fluorescence excitation spectroscopy provides information about human skin in vivo, J. Invest. Dermatol., 2000, 115, 704\u2013707.","journal-title":"J. Invest. Dermatol."},{"key":"7011017_CR19","doi-asserted-by":"publisher","first-page":"776","DOI":"10.1046\/j.1523-1747.1998.00377.x","volume":"111","author":"N Kollias","year":"1998","unstructured":"N. Kollias, R. Gillies, M. Moran, I. E. Kochevar and R. R. Anderson, Endogenous skin fluorescence includes bands that may serve as quantitative markers of aging and photoaging, J. Invest. Dermatol, 1998, 111, 776\u2013780.","journal-title":"J. Invest. Dermatol"},{"key":"7011017_CR20","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1046\/j.1523-1747.2001.01285.x","volume":"116","author":"R Na","year":"2001","unstructured":"R. Na, I. M. Stender, M. Henriksen and H. C. Wulf, Autofluorescence of human skin is age-related after correction for skin pigmentation and redness, J. Invest. Dermatol., 2001, 116, 536\u2013540.","journal-title":"J. Invest. Dermatol."},{"key":"7011017_CR21","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1016\/0026-0495(92)90059-J","volume":"41","author":"P R Odetti","year":"1992","unstructured":"P. R. Odetti, A. Borgoglio and R. Rolandi, Age-related increase of collagen fluorescence in human subcutaneous tissue, Metabolism, 1992, 41, 655\u2013658.","journal-title":"Metabolism"},{"key":"7011017_CR22","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/S0005-2760(97)00019-2","volume":"1346","author":"T Gildenast","year":"1997","unstructured":"T. Gildenast and J. Lasch, Isolation of ceramide fractions from human stratum corneum lipid extracts by high-performance liquid chromatography, Biochim. Biophys. Acta, 1997, 1346, 69\u201374.","journal-title":"Biochim. Biophys. Acta"},{"key":"7011017_CR23","first-page":"20","volume-title":"Encyclopedia of Analytical Chemistry","author":"N Ramanujam","year":"2000","unstructured":"N. Ramanujam, Fluorescence spectroscopy in vivo, in Encyclopedia of Analytical Chemistry, ed. R. A. Meyers, J. Wiley, & Sons, Chichester, 2000, pp. 20\u201356."},{"key":"7011017_CR24","doi-asserted-by":"publisher","first-page":"6268","DOI":"10.1364\/OPEX.13.006268","volume":"13","author":"A M Pena","year":"2005","unstructured":"A. M. Pena, M. Strupler, T. Boulesteix, M. C. Schanne-Klein, Spectroscopic analysis of keratin endogenous signal for skin multiphoton microscopy, Opt. Express, 2005, 13, 6268\u20136274.","journal-title":"Opt. Express"},{"key":"7011017_CR25","doi-asserted-by":"publisher","first-page":"31780","DOI":"10.1074\/jbc.M314005200","volume":"279","author":"J V Rocheleau","year":"2004","unstructured":"J. V. Rocheleau, W. S. Head and D. W. Piston, Quantitative NAD(P)H\/Flavoprotein Autofluorescence Imaging Reveals Metabolic Mechanisms of Pancreatic Islet Pyruvate Response, J. Biol. Chem., 2004, 279, 31780\u201331787.","journal-title":"J. Biol. Chem."}],"container-title":["Photochemical &amp; Photobiological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1039\/b808776h.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1039\/b808776h\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2008\/PP\/B808776H","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1039\/b808776h.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T09:36:43Z","timestamp":1667381803000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1039\/b808776h"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11]]},"references-count":25,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2008,11]]}},"alternative-id":["7011017"],"URL":"https:\/\/doi.org\/10.1039\/b808776h","relation":{},"ISSN":["1474-905X","1474-9092"],"issn-type":[{"value":"1474-905X","type":"print"},{"value":"1474-9092","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,11]]},"assertion":[{"value":"28 May 2008","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 August 2008","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 November 2008","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}