{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T14:19:29Z","timestamp":1790864369363,"version":"4.1.0"},"reference-count":52,"publisher":"Royal Society of Chemistry (RSC)","issue":"24","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Org. Biomol. Chem."],"published-print":{"date-parts":[[2009]]},"DOI":"10.1039\/b913333j","type":"journal-article","created":{"date-parts":[[2009,10,14]],"date-time":"2009-10-14T12:03:47Z","timestamp":1255521827000},"page":"5129","source":"Crossref","is-referenced-by-count":36,"title":["Rapid synthesis of Abelson tyrosine kinase inhibitors using click chemistry"],"prefix":"10.1039","volume":"7","author":[{"given":"Karunakaran A.","family":"Kalesh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shao Q.","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","reference":[{"key":"b913333j-(cit1a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1021\/cr000230w","volume":"101","author":"Adams","year":"2001","journal-title":"Chem. Rev."},{"key":"b913333j-(cit1b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0092-8674(00)81688-8","volume":"100","author":"Hunter","year":"2000","journal-title":"Cell"},{"key":"b913333j-(cit1c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1038\/nrm2203","volume":"8","author":"Ubersax","year":"2007","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"b913333j-(cit2a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1038\/nrd773","volume":"1","author":"Cohen","year":"2002","journal-title":"Nat. Rev. Drug Discovery"},{"key":"b913333j-(cit2b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S1535-6108(02)00022-3","volume":"1","author":"Sawyers","year":"2002","journal-title":"Cancer Cell"},{"key":"b913333j-(cit2c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1056\/NEJMra044389","volume":"353","author":"Krause","year":"2005","journal-title":"N. Engl. J. Med."},{"key":"b913333j-(cit3a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1038\/nchembio799","volume":"2","author":"Liu","year":"2006","journal-title":"Nat. Chem. Biol."},{"key":"b913333j-(cit3b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1038\/nsb770","volume":"9","author":"Pargellis","year":"2002","journal-title":"Nat. Struct. Biol."},{"key":"b913333j-(cit3c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5389","DOI":"10.1016\/j.bmcl.2004.08.007","volume":"14","author":"Cumming","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"b913333j-(cit3d)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.bbapap.2003.11.010","volume":"1697","author":"Manley","year":"2004","journal-title":"Biochim. Biophys. Acta"},{"key":"b913333j-(cit3e)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/S0092-8674(04)00215-6","volume":"116","author":"Wan","year":"2004","journal-title":"Cell"},{"key":"b913333j-(cit3f)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1021\/jm049575n","volume":"48","author":"Gill","year":"2005","journal-title":"J. Med. Chem."},{"key":"b913333j-(cit3g)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/83028","volume":"8","author":"Parang","year":"2001","journal-title":"Nat. Struct. Biol."},{"key":"b913333j-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1073\/pnas.0408283102","volume":"102","author":"Gumireddy","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"b913333j-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/nchembio760","volume":"2","author":"Adri\u00e0n","year":"2006","journal-title":"Nat. Chem. Biol."},{"key":"b913333j-(cit6a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1002\/cbic.200700583","volume":"9","author":"Lee","year":"2008","journal-title":"ChemBioChem"},{"key":"b913333j-(cit6b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"13812","DOI":"10.1021\/ja076197d","volume":"129","author":"Meyer","year":"2007","journal-title":"J. Am. Chem. Soc."},{"key":"b913333j-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/S0092-8674(03)00194-6","volume":"112","author":"Nagar","year":"2003","journal-title":"Cell"},{"key":"b913333j-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1126\/science.289.5486.1938","volume":"289","author":"Schindler","year":"2000","journal-title":"Science"},{"key":"b913333j-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3343","DOI":"10.1182\/blood.V96.10.3343","volume":"96","author":"Deininger","year":"2000","journal-title":"Blood"},{"key":"b913333j-(cit10a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.bbapap.2005.07.040","volume":"1754","author":"Manley","year":"2005","journal-title":"Biochim. Biophys. Acta"},{"key":"b913333j-(cit10b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1126\/science.1062538","volume":"293","author":"Gorre","year":"2001","journal-title":"Science"},{"key":"b913333j-(cit10c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S0140-6736(02)07679-1","volume":"359","author":"von Bubnoff","year":"2002","journal-title":"Lancet"},{"key":"b913333j-(cit11a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.ccr.2005.01.020","volume":"7","author":"O'Hare","year":"2005","journal-title":"Cancer Cell"},{"key":"b913333j-(cit11b)\/*[position()=1]","first-page":"7149","volume":"62","author":"La Rosee","year":"2002","journal-title":"Cancer Res."},{"key":"b913333j-(cit11c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5790","DOI":"10.1158\/0008-5472.CAN-05-4187","volume":"66","author":"Tokarski","year":"2006","journal-title":"Cancer Res."},{"key":"b913333j-(cit11d)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5793","DOI":"10.1016\/j.bmcl.2004.09.042","volume":"14","author":"Manley","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"b913333j-(cit12a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1002\/qsar.200740064","volume":"26","author":"Kalesh","year":"2007","journal-title":"QSAR Comb. Sci."},{"key":"b913333j-(cit12b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1039\/b600055j","volume":"4","author":"Brik","year":"2006","journal-title":"Org. Biomol. Chem."},{"key":"b913333j-(cit13a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2596","DOI":"10.1002\/1521-3773(20020715)41:14<2596::AID-ANIE2596>3.0.CO;2-4","volume":"41","author":"Rostovtsev","year":"2002","journal-title":"Angew. Chem., Int. Ed."},{"key":"b913333j-(cit13b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3057","DOI":"10.1021\/jo011148j","volume":"67","author":"Tornoe","year":"2002","journal-title":"J. Org. Chem."},{"key":"b913333j-(cit13c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1016\/S1359-6446(03)02933-7","volume":"8","author":"Kolb","year":"2003","journal-title":"Drug Discovery Today"},{"key":"b913333j-(cit13d)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/S1074-5521(02)00184-9","volume":"9","author":"Brik","year":"2002","journal-title":"Chem. Biol."},{"key":"b913333j-(cit13e)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1002\/anie.200502161","volume":"45","author":"Whiting","year":"2006","journal-title":"Angew. Chem., Int. Ed."},{"key":"b913333j-(cit13f)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1002\/cbic.200300841","volume":"5","author":"Best","year":"2004","journal-title":"ChemBioChem"},{"key":"b913333j-(cit13g)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9588","DOI":"10.1021\/ja0302836","volume":"125","author":"Lee","year":"2003","journal-title":"J. Am. Chem. Soc."},{"key":"b913333j-(cit13h)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3821","DOI":"10.1021\/ol061431a","volume":"8","author":"Wang","year":"2006","journal-title":"Org. Lett."},{"key":"b913333j-(cit13i)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"12809","DOI":"10.1021\/ja046382g","volume":"126","author":"Manetsch","year":"2004","journal-title":"J. Am. Chem. Soc."},{"key":"b913333j-(cit13j)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1021\/ol052895w","volume":"8","author":"Srinivasan","year":"2006","journal-title":"Org. Lett."},{"key":"b913333j-(cit13k)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1039\/b718304f","volume":"6","author":"Ng","year":"2008","journal-title":"Org. Biomol. Chem."},{"key":"b913333j-(cit13l)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4839","DOI":"10.1016\/j.bmc.2008.03.050","volume":"16","author":"Chen","year":"2008","journal-title":"Bioorg. Med. Chem."},{"key":"b913333j-(cit13m)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5529","DOI":"10.1021\/ol802286g","volume":"10","author":"Hu","year":"2008","journal-title":"Org. Lett."},{"key":"b913333j-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1039\/b902338k","volume":"7","author":"Srinivasan","year":"2009","journal-title":"Org. Biomol. Chem."},{"key":"b913333j-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9588","DOI":"10.1021\/ja0302836","volume":"125","author":"Lee","year":"2003","journal-title":"J. Am. Chem. Soc."},{"key":"b913333j-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1021\/op700270n","volume":"12","author":"Liu","year":"2008","journal-title":"Org. Process Res. Dev."},{"key":"b913333j-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3135","DOI":"10.1110\/ps.051750905","volume":"14","author":"Seeliger","year":"2005","journal-title":"Protein Sci."},{"key":"b913333j-(cit18a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1007\/s00216-006-0511-5","volume":"386","author":"Sun","year":"2006","journal-title":"Anal. Bioanal. Chem."},{"key":"b913333j-(cit18b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1021\/ar9000586","volume":"42","author":"Uttamchandani","year":"2009","journal-title":"Acc. Chem. Res."},{"key":"b913333j-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1021\/ja01464a034","volume":"83","author":"Moffatt","year":"1961","journal-title":"J. Am. Chem. Soc."},{"key":"b913333j-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1021\/jm049546c","volume":"48","author":"Szak\u00e1cs","year":"2005","journal-title":"J. Med. Chem."},{"key":"b913333j-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1021\/jm00205a006","volume":"21","author":"Bennett","year":"1978","journal-title":"J. Med. Chem."},{"key":"b913333j-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8127","DOI":"10.1021\/jo0107296","volume":"66","author":"Lautens","year":"2001","journal-title":"J. Org. Chem."}],"container-title":["Organic &amp; Biomolecular Chemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2009\/OB\/B913333J","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T21:54:19Z","timestamp":1782942859000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/ob\/article\/7\/24\/5129-5136\/205577"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":52,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2009]]}},"URL":"https:\/\/doi.org\/10.1039\/b913333j","relation":{},"ISSN":["1477-0520","1477-0539"],"issn-type":[{"value":"1477-0520","type":"print"},{"value":"1477-0539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009]]}}}