{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T23:48:26Z","timestamp":1789602506420,"version":"build-2803163510"},"reference-count":56,"publisher":"Royal Society of Chemistry (RSC)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Food Funct."],"published-print":{"date-parts":[[2014]]},"DOI":"10.1039\/c3fo60345h","type":"journal-article","created":{"date-parts":[[2014,1,9]],"date-time":"2014-01-09T10:32:02Z","timestamp":1389263522000},"page":"916","source":"Crossref","is-referenced-by-count":5,"title":["Epigallocatechin-3-gallate restores the Bcl-2 expression in liver of young rats challenged with hypercholesterolemia but not in aged rats: an insight into its disparity of efficacy on advancing age"],"prefix":"10.1039","volume":"5","author":[{"given":"Thulasi Raman","family":"Krishnan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prema","family":"Velusamy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suresh","family":"Mangaiah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashokkumar","family":"Srinivasan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Senthil Kumaran","family":"Vadivel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uma","family":"Murugaiyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalaiselvi","family":"Periandavan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","reference":[{"issue":"4","key":"c3fo60345h-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1152\/japplphysiol.00288.2003","volume":"95","author":"Weinert","year":"2003","journal-title":"J. Appl. Physiol."},{"key":"c3fo60345h-(cit2)\/*[position()=1]","first-page":"420139","author":"Trapani","year":"2010","journal-title":"Curr. Gerontol. Geriatr. Res."},{"issue":"2","key":"c3fo60345h-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1002\/hep.20781","volume":"42","author":"Villanova","year":"2005","journal-title":"Hepatology"},{"issue":"3","key":"c3fo60345h-(cit6)\/*[position()=1]","first-page":"G553","volume":"296","author":"Ferr\u00e9","year":"2009","journal-title":"Am. J. Physiol.: Gastrointest. Liver Physiol."},{"issue":"6\u20137","key":"c3fo60345h-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/j.mad.2005.03.003","volume":"126","author":"Langley-Evans","year":"2005","journal-title":"Mech. Ageing Dev."},{"issue":"5","key":"c3fo60345h-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1161\/01.CIR.81.5.1721","volume":"81","author":"LaRosa","year":"1990","journal-title":"Circulation"},{"issue":"10","key":"c3fo60345h-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.1093\/jn\/130.10.2409","volume":"130","author":"Yang","year":"2000","journal-title":"J. Nutr."},{"issue":"6","key":"c3fo60345h-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1698S","DOI":"10.1093\/ajcn\/71.6.1698S","volume":"71","author":"Mukhtar","year":"2000","journal-title":"Am. J. Clin. Nutr."},{"issue":"3","key":"c3fo60345h-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.exger.2007.10.017","volume":"43","author":"Senthil Kumaran","year":"2008","journal-title":"Exp. Gerontol."},{"issue":"1","key":"c3fo60345h-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0021-9258(18)64849-5","volume":"226","author":"Folch","year":"1957","journal-title":"J. Biol. Chem."},{"key":"c3fo60345h-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1021\/ac60294a044","volume":"42","author":"Parekh","year":"1970","journal-title":"Anal. Chem."},{"key":"c3fo60345h-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/BF01369597","volume":"109","author":"Iwasa","year":"1996","journal-title":"J. Leg. Med."},{"issue":"5","key":"c3fo60345h-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1248\/jhs.48.393","volume":"48","author":"Dioka","year":"2002","journal-title":"J. Health Sci."},{"issue":"3","key":"c3fo60345h-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1530\/JOE-11-0406","volume":"2013","author":"Ghosh","year":"2012","journal-title":"J. Endocrinol."},{"key":"c3fo60345h-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1590\/S1516-89132005000200006","volume":"48","author":"Matos 1","year":"2005","journal-title":"Braz. Arch. Biol. Technol."},{"issue":"6","key":"c3fo60345h-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1006\/phrs.1997.0176","volume":"35","author":"Yang","year":"1997","journal-title":"Pharmacol. Res."},{"issue":"12","key":"c3fo60345h-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.exger.2009.08.010","volume":"44","author":"Senthil Kumaran","year":"2009","journal-title":"Exp. Gerontol."},{"issue":"3","key":"c3fo60345h-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"312","DOI":"10.5483\/BMBRep.2003.36.3.312","volume":"36","author":"Ryu","year":"2003","journal-title":"J. Biochem. Mol. Biol."},{"issue":"3","key":"c3fo60345h-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.bbalip.2009.09.015","volume":"1801","author":"Chavez","year":"2010","journal-title":"Biochim. Biophys. Acta"},{"issue":"6981","key":"c3fo60345h-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1136\/bmj.310.6981.693","volume":"310","author":"Imai","year":"1995","journal-title":"BMJ"},{"issue":"12","key":"c3fo60345h-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1001\/archinte.163.12.1448","volume":"163","author":"Maron","year":"2003","journal-title":"Arch. Intern. Med."},{"issue":"5","key":"c3fo60345h-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0024-3205(99)00607-4","volume":"66","author":"Yang","year":"2000","journal-title":"Life Sci."},{"issue":"5","key":"c3fo60345h-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/S0895-3988(10)60015-3","volume":"22","author":"Hamden","year":"2009","journal-title":"Biomed. Environ. Sci."},{"issue":"11","key":"c3fo60345h-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1016\/j.exger.2006.09.002","volume":"41","author":"Escames","year":"2006","journal-title":"Exp. Gerontol."},{"issue":"4","key":"c3fo60345h-(cit28)\/*[position()=1]","first-page":"246","volume":"15","author":"Burt","year":"1998","journal-title":"Semin. Diagn. Pathol."},{"key":"c3fo60345h-(cit29)\/*[position()=1]","first-page":"17","author":"Angulo","year":"2002","journal-title":"J. Gastroenterol. Hepatol."},{"issue":"2","key":"c3fo60345h-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"123","DOI":"10.3177\/jnsv.57.123","volume":"57","author":"Honma","year":"2011","journal-title":"J. Nutr. Sci. Vitaminol."},{"issue":"1","key":"c3fo60345h-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1111\/j.1440-1746.2010.06547.x","volume":"26","author":"Okanoue","year":"2011","journal-title":"J. Gastroenterol. Hepatol."},{"issue":"4","key":"c3fo60345h-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.cld.2009.07.005","volume":"13","author":"Argo","year":"2009","journal-title":"Clin. Liver. Dis."},{"issue":"7","key":"c3fo60345h-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1503\/cmaj.045232","volume":"172","author":"Adams","year":"2005","journal-title":"Can. Med. Assoc. J."},{"issue":"6","key":"c3fo60345h-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1111\/j.1478-3231.2004.0969.x","volume":"24","author":"Kagansky","year":"2004","journal-title":"Liver Int."},{"issue":"10","key":"c3fo60345h-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2219","DOI":"10.1093\/jn\/137.10.2219","volume":"137","author":"Torres-Gonzalez","year":"2007","journal-title":"J. Nutr."},{"issue":"2","key":"c3fo60345h-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1002\/hep.22363","volume":"48","author":"Wouters","year":"2008","journal-title":"Hepatology"},{"issue":"10","key":"c3fo60345h-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1007\/s00535-006-1883-1","volume":"41","author":"Kainuma","year":"2006","journal-title":"J. Gastroenterol."},{"issue":"10","key":"c3fo60345h-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1093\/eurheartj\/ehr453","volume":"33","author":"Bhatia","year":"2012","journal-title":"Eur. Heart J."},{"issue":"4","key":"c3fo60345h-(cit39)\/*[position()=1]","first-page":"481","volume":"14","author":"Sayama","year":"2000","journal-title":"In Vivo"},{"issue":"11","key":"c3fo60345h-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1038\/sj.ijo.0802141","volume":"26","author":"Murase","year":"2002","journal-title":"Int. J. Obes. Relat. Metab. Disord."},{"issue":"9","key":"c3fo60345h-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1093\/jn\/138.9.1677","volume":"138","author":"Bose","year":"2008","journal-title":"J. Nutr."},{"key":"c3fo60345h-(cit42)\/*[position()=1]","author":"Xiao","year":"2013","journal-title":"Eur. J. Nutr."},{"issue":"2","key":"c3fo60345h-(cit43)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/S0016-5085(03)00907-7","volume":"125","author":"Feldstein","year":"2003","journal-title":"Gastroenterology"},{"issue":"10","key":"c3fo60345h-(cit44)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2547","DOI":"10.1093\/jn\/136.10.2547","volume":"136","author":"Wang","year":"2006","journal-title":"J. Nutr."},{"issue":"9","key":"c3fo60345h-(cit45)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1111\/j.1572-0241.2004.40009.x","volume":"99","author":"Ribeiro","year":"2004","journal-title":"Am. J. Gastroenterol."},{"issue":"4","key":"c3fo60345h-(cit46)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1002\/hep.23126","volume":"50","author":"Hikita","year":"2009","journal-title":"Hepatology"},{"issue":"2","key":"c3fo60345h-(cit47)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1002\/hep.22664","volume":"49","author":"Vick","year":"2009","journal-title":"Hepatology"},{"issue":"3","key":"c3fo60345h-(cit48)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"242","DOI":"10.2174\/1874609811205030012","volume":"5","author":"Tresguerres","year":"2012","journal-title":"Curr. Aging Sci."},{"issue":"20","key":"c3fo60345h-(cit49)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9685","DOI":"10.1021\/jf8020255","volume":"56","author":"Hsu","year":"2008","journal-title":"J. Agric. Food Chem."},{"issue":"9","key":"c3fo60345h-(cit50)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1194\/jlr.M016246","volume":"52","author":"Subramanian","year":"2011","journal-title":"J. Lipid Res."},{"key":"c3fo60345h-(cit52)\/*[position()=1]","first-page":"1","volume":"282","author":"Matassov","year":"2004","journal-title":"Methods Mol. Biol."},{"issue":"7","key":"c3fo60345h-(cit53)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1161\/hh0701.088684","volume":"88","author":"Martinet","year":"2001 Apr 13","journal-title":"Circ. Res."},{"issue":"7","key":"c3fo60345h-(cit54)\/*[position()=1]","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1139\/cjpp-2012-0347","volume":"91","author":"Thangapandiyan","year":"2013 Jul","journal-title":"Can. J. Physiol. Pharmacol."},{"issue":"2","key":"c3fo60345h-(cit55)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1089\/jmf.2011.1625","volume":"15","author":"Kam","year":"2012","journal-title":"J. Med. Food"},{"issue":"2","key":"c3fo60345h-(cit56)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0169-328X(00)00163-7","volume":"80","author":"Masumura","year":"2000","journal-title":"Mol. Brain Res."},{"issue":"5","key":"c3fo60345h-(cit57)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/S0024-3205(01)01438-2","volume":"70","author":"Choi","year":"2001","journal-title":"Life Sci."},{"issue":"3","key":"c3fo60345h-(cit58)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.neulet.2006.09.089","volume":"411","author":"Jung","year":"2007","journal-title":"Neurosci. Lett."},{"issue":"2","key":"c3fo60345h-(cit59)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.1745-7254.2007.00495.x","volume":"28","author":"Sheng","year":"2007","journal-title":"Acta Pharmacol. Sin."},{"issue":"2","key":"c3fo60345h-(cit60)\/*[position()=1]","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1016\/j.jss.2008.08.038","volume":"159","author":"Giakoustidis","year":"2010 Apr","journal-title":"J. Surg. Res."}],"container-title":["Food & Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2014\/FO\/C3FO60345H","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T17:25:49Z","timestamp":1782926749000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/5\/5\/916-926\/402958"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":56,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1039\/c3fo60345h","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}