{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T18:29:49Z","timestamp":1783016989421,"version":"3.54.6"},"reference-count":33,"publisher":"Royal Society of Chemistry (RSC)","issue":"7","content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Analyst"],"abstract":"<p>We report results from a study utilizing infrared spectral cytopathology (SCP) to detect abnormalities in exfoliated esophageal cells.<\/p>","DOI":"10.1039\/c4an01884b","type":"journal-article","created":{"date-parts":[[2014,12,19]],"date-time":"2014-12-19T02:40:39Z","timestamp":1418956839000},"page":"2215-2223","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Infrared micro-spectroscopy for cyto-pathological classification of esophageal cells"],"prefix":"10.1039","volume":"140","author":[{"given":"Douglas","family":"Townsend","sequence":"first","affiliation":[{"name":"Laboratory for Spectral Diagnosis"},{"name":"Department of Chemistry and Chemical Biology"},{"name":"Northeastern University"},{"name":"Boston"},{"name":"USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milo\u0161","family":"Miljkovi\u0107","sequence":"additional","affiliation":[{"name":"Laboratory for Spectral Diagnosis"},{"name":"Department of Chemistry and Chemical Biology"},{"name":"Northeastern University"},{"name":"Boston"},{"name":"USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Bird","sequence":"additional","affiliation":[{"name":"Laboratory for Spectral Diagnosis"},{"name":"Department of Chemistry and Chemical Biology"},{"name":"Northeastern University"},{"name":"Boston"},{"name":"USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Lenau","sequence":"additional","affiliation":[{"name":"Laboratory for Spectral Diagnosis"},{"name":"Department of Chemistry and Chemical Biology"},{"name":"Northeastern University"},{"name":"Boston"},{"name":"USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Old","sequence":"additional","affiliation":[{"name":"Biophotonics Research Unit"},{"name":"Gloucestershire Hospitals NHS Foundation Trust"},{"name":"Gloucester"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"Almond","sequence":"additional","affiliation":[{"name":"Biophotonics Research Unit"},{"name":"Gloucestershire Hospitals NHS Foundation Trust"},{"name":"Gloucester"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Kendall","sequence":"additional","affiliation":[{"name":"Biophotonics Research Unit"},{"name":"Gloucestershire Hospitals NHS Foundation Trust"},{"name":"Gloucester"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gavin","family":"Lloyd","sequence":"additional","affiliation":[{"name":"Biophotonics Research Unit"},{"name":"Gloucestershire Hospitals NHS Foundation Trust"},{"name":"Gloucester"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil","family":"Shepherd","sequence":"additional","affiliation":[{"name":"Department of Pathology"},{"name":"Gloucestershire Royal Hospital"},{"name":"Gloucester"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugh","family":"Barr","sequence":"additional","affiliation":[{"name":"Department of Upper GI Surgery"},{"name":"Gloucestershire Royal Hospital"},{"name":"Gloucester"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nick","family":"Stone","sequence":"additional","affiliation":[{"name":"Biomedical Physics"},{"name":"School of Physics"},{"name":"University of Exeter"},{"name":"Exeter EX4 4QL"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"Diem","sequence":"additional","affiliation":[{"name":"Laboratory for Spectral Diagnosis"},{"name":"Department of Chemistry and Chemical Biology"},{"name":"Northeastern University"},{"name":"Boston"},{"name":"USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2015]]},"reference":[{"issue":"6","key":"C4AN01884B-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1001\/jama.2013.226450","volume":"310","author":"Spechler","year":"2013","journal-title":"JAMA"},{"issue":"6","key":"C4AN01884B-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"334","DOI":"10.3322\/canjclin.55.6.334","volume":"55","author":"Souza","year":"2005","journal-title":"CA-Cancer J. Clin."},{"issue":"2","key":"C4AN01884B-(cit3)\/*[position()=1]","first-page":"88","volume":"8","author":"Barr","year":"2006","journal-title":"MedGenMed"},{"key":"C4AN01884B-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1053\/j.gastro.2011.01.031","volume":"140","author":"Spechler","year":"2011","journal-title":"Gastroenterology"},{"issue":"10","key":"C4AN01884B-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1016\/S1542-3565(04)00394-5","volume":"2","author":"Gerson","year":"2004","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"C4AN01884B-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.canlet.2008.07.006","volume":"275","author":"Zhang","year":"2009","journal-title":"Cancer Lett."},{"issue":"103","key":"C4AN01884B-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1111\/j.1572-0241.2008.01835.x","volume":"103","author":"Wang","year":"2008","journal-title":"Am. J. Gastroenterol."},{"key":"C4AN01884B-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1055\/s-2005-870433","volume":"37","author":"Kara","year":"2005","journal-title":"Endoscopy"},{"issue":"1","key":"C4AN01884B-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1136\/gutjnl-2013-305372","volume":"63","author":"Fitzgerald","year":"2014","journal-title":"Gut"},{"key":"C4AN01884B-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1053\/hupa.2001.23510","volume":"32","author":"Montgomery","year":"2001","journal-title":"Hum. Pathol."},{"key":"C4AN01884B-(cit11)\/*[position()=1]","volume-title":"Barrett's oesophagus: risk of malignant progression and cost effectiveness of endoscopic surveillance","author":"Bhat","year":"2012","unstructured":"S. Bhat , Barrett's oesophagus: risk of malignant progression and cost effectiveness of endoscopic surveillance, 2012"},{"key":"C4AN01884B-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"c4372","DOI":"10.1136\/bmj.c4372","volume":"341","author":"Kadri","year":"2010","journal-title":"BMJ"},{"key":"C4AN01884B-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1038\/labinvest.2010.1","volume":"90","author":"Papamarkakis","year":"2010","journal-title":"Lab. Invest."},{"issue":"1","key":"C4AN01884B-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.vibspec.2008.03.006","volume":"48","author":"Bird","year":"2008","journal-title":"Vib. Spectrosc."},{"key":"C4AN01884B-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1038\/labinvest.2010.72","volume":"90","author":"Schubert","year":"2010","journal-title":"Lab. Invest."},{"key":"C4AN01884B-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1039\/C2AN36090J","volume":"138","author":"Bassan","year":"2013","journal-title":"Analyst"},{"key":"C4AN01884B-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.vibspec.2013.09.008","volume":"69","author":"Wrobel","year":"2013","journal-title":"Vib. Spectrosc."},{"key":"C4AN01884B-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3975","DOI":"10.1039\/c3an00185g","volume":"138","author":"Miljkovi\u0107","year":"2013","journal-title":"Analyst"},{"issue":"8\u20139","key":"C4AN01884B-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1002\/jbio.201000023","volume":"3","author":"Schubert","year":"2010","journal-title":"J. Biophotonics"},{"key":"C4AN01884B-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1039\/B921056C","volume":"135","author":"Bassan","year":"2010","journal-title":"Analyst"},{"key":"C4AN01884B-(cit21)\/*[position()=1]","unstructured":"IHCWorld. Protocol OG6. Available from: http:\/\/www.ihcworld.com\/_protocols\/special_stains\/papanicolaou_stain.htm"},{"issue":"5","key":"C4AN01884B-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/cem.993","volume":"20","author":"Lasch","year":"2007","journal-title":"J. Chemom."},{"key":"C4AN01884B-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","DOI":"10.1039\/9781847550484","volume-title":"Chemometrics in Analytical Spectroscopy","author":"Adams","year":"2004","unstructured":"M. J. Adams , in Chemometrics in Analytical Spectroscopy, RSC Analytical Spectroscopy Monographs, ed. N. W. Barnett, Royal Society of Chemistry, Cambridge, 2nd edn, 2004"},{"key":"C4AN01884B-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"15327","DOI":"10.1073\/pnas.95.26.15327","volume":"95","author":"Cohenford","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"C4AN01884B-(cit25)\/*[position()=1]","author":"Akalin","year":"2015","journal-title":"Lab. Invest."},{"key":"C4AN01884B-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1002\/bip.10435","volume":"72","author":"Jamin","year":"2003","journal-title":"Biopolymers"},{"key":"C4AN01884B-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2302","DOI":"10.1021\/ja407583r","volume":"136","author":"Kurouski","year":"2014","journal-title":"J. Am. Chem. Soc."},{"issue":"7","key":"C4AN01884B-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/j.bbamem.2006.05.010","volume":"1758","author":"Romeo","year":"2006","journal-title":"Biochim. Biophys. Acta"},{"issue":"9","key":"C4AN01884B-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1038\/nrc2918","volume":"10","author":"Hanash","year":"2010","journal-title":"Nat. Rev. Cancer"},{"key":"C4AN01884B-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3038","DOI":"10.1039\/c0an00536c","volume":"135","author":"Kendall","year":"2010","journal-title":"Analyst"},{"issue":"7","key":"C4AN01884B-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1002\/jrs.882","volume":"33","author":"Stone","year":"2002","journal-title":"J. Raman Spectrosc."},{"issue":"1","key":"C4AN01884B-(cit32)\/*[position()=1]","first-page":"219","volume":"44","author":"Chiriboga","year":"1998","journal-title":"Cell. Mol. Biol."},{"issue":"8","key":"C4AN01884B-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1366\/0003702011953018","volume":"55","author":"Utzinger","year":"2001","journal-title":"Appl. Spectrosc."}],"container-title":["The Analyst"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2015\/AN\/C4AN01884B","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T17:31:23Z","timestamp":1783013483000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/an\/article\/140\/7\/2215-2223\/424124"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":33,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.1039\/c4an01884b","relation":{},"ISSN":["0003-2654","1364-5528"],"issn-type":[{"value":"0003-2654","type":"print"},{"value":"1364-5528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Douglas Townsend (ResearcherID)","URL":"http:\/\/www.researcherid.com\/rid\/N-2779-2014","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"The Royal Society of Chemistry has an exclusive publication licence for this journal","name":"copyright_licence","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"The accepted version of this article will be made freely available after a 12 month embargo period","name":"copyright_licence","label":"OPEN ACCESS","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 17 October 2014; Accepted 18 December 2014; Accepted Manuscript published 18 December 2014; Advance Article published 16 January 2015; Version of Record published 16 March 2015","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}