{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T05:07:58Z","timestamp":1791522478825,"version":"4.3.4"},"reference-count":50,"publisher":"Royal Society of Chemistry (RSC)","issue":"1","content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<p>\n                    Bioassay-guided isolation of acetogenins from avocado pulp with\n                    <italic>in vitro<\/italic>\n                    antiplatelet aggregation and\n                    <italic>in vivo<\/italic>\n                    antithrombotic effects in CD1 mice.\n                  <\/p>","DOI":"10.1039\/c4fo00610k","type":"journal-article","created":{"date-parts":[[2014,9,23]],"date-time":"2014-09-23T05:03:44Z","timestamp":1411448624000},"page":"192-202","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Isolation and chemical identification of lipid derivatives from avocado (Persea americana) pulp with antiplatelet and antithrombotic activities"],"prefix":"10.1039","volume":"6","author":[{"given":"Dariana Graciela","family":"Rodriguez-Sanchez","sequence":"first","affiliation":[{"name":"C\u00e1tedra de Cardiolog\u00eda y Medicina Vascular"},{"name":"Escuela de Medicina"},{"name":"Tecnol\u00f3gico de Monterrey"},{"name":"Monterrey"},{"name":"Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirthala","family":"Flores-Garc\u00eda","sequence":"additional","affiliation":[{"name":"Departamento de Biolog\u00eda Molecular"},{"name":"Instituto Nacional de Cardiolog\u00eda Ignacio Chav\u00e9z"},{"name":"M\u00e9xico City"},{"name":"Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Silva-Platas","sequence":"additional","affiliation":[{"name":"C\u00e1tedra de Cardiolog\u00eda y Medicina Vascular"},{"name":"Escuela de Medicina"},{"name":"Tecnol\u00f3gico de Monterrey"},{"name":"Monterrey"},{"name":"Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheryl","family":"Rizzo","sequence":"additional","affiliation":[{"name":"C\u00e1tedra de Cardiolog\u00eda y Medicina Vascular"},{"name":"Escuela de Medicina"},{"name":"Tecnol\u00f3gico de Monterrey"},{"name":"Monterrey"},{"name":"Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Torre-Amione","sequence":"additional","affiliation":[{"name":"C\u00e1tedra de Cardiolog\u00eda y Medicina Vascular"},{"name":"Escuela de Medicina"},{"name":"Tecnol\u00f3gico de Monterrey"},{"name":"Monterrey"},{"name":"Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurora","family":"De la Pe\u00f1a-Diaz","sequence":"additional","affiliation":[{"name":"Departamento de Biolog\u00eda Molecular"},{"name":"Instituto Nacional de Cardiolog\u00eda Ignacio Chav\u00e9z"},{"name":"M\u00e9xico City"},{"name":"Mexico"},{"name":"Departamento de Farmacolog\u00eda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Hern\u00e1ndez-Brenes","sequence":"additional","affiliation":[{"name":"Departamento de Biotecnolog\u00eda y Alimentos"},{"name":"Escuela de Biotecnolog\u00eda e Ingenier\u00eda de Alimentos"},{"name":"Tecnol\u00f3gico de Monterrey"},{"name":"Monterrey"},{"name":"Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerardo","family":"Garc\u00eda-Rivas","sequence":"additional","affiliation":[{"name":"C\u00e1tedra de Cardiolog\u00eda y Medicina Vascular"},{"name":"Escuela de Medicina"},{"name":"Tecnol\u00f3gico de Monterrey"},{"name":"Monterrey"},{"name":"Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2015]]},"reference":[{"key":"C4FO00610K-(cit1)\/*[position()=1]","unstructured":"[OMS], O.M.d.1.S. Cardiovascular diseases, 2011 [cited 2011 May]; Available from: http:\/\/www.who.int\/cardiovascular_diseases\/en\/"},{"issue":"2","key":"C4FO00610K-(cit2)\/*[position()=1]","first-page":"28","volume":"52","author":"Tselepis","year":"2011","journal-title":"Hellenic J. Cardiol."},{"issue":"2","key":"C4FO00610K-(cit3)\/*[position()=1]","first-page":"248","volume":"102","author":"Jennings","year":"2009","journal-title":"Thromb. Haemost."},{"issue":"12","key":"C4FO00610K-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5087","DOI":"10.1182\/blood-2006-12-027698","volume":"109","author":"Jackson","year":"2007","journal-title":"Blood"},{"issue":"3","key":"C4FO00610K-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1111\/j.1476-5381.2009.00555.x","volume":"159","author":"Siller-Matula","year":"2010","journal-title":"Br. J. Pharmacol."},{"issue":"Suppl 1","key":"C4FO00610K-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.1016\/j.thromres.2008.08.011","volume":"123","author":"Johnson","year":"2008","journal-title":"Thromb. Res."},{"issue":"1","key":"C4FO00610K-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.nut.2004.09.010","volume":"21","author":"Pieterse","year":"2005","journal-title":"Nutrition"},{"issue":"2","key":"C4FO00610K-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1093\/ajcn\/79.2.204","volume":"79","author":"Pelkman","year":"2004","journal-title":"Am. J. Clin. Nutr."},{"issue":"4","key":"C4FO00610K-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/S0002-8223(01)00102-X","volume":"101","author":"Duester","year":"2001","journal-title":"J. Am. Diet. Assoc."},{"issue":"4","key":"C4FO00610K-(cit10)\/*[position()=1]","first-page":"267","volume":"24","author":"Carranza","year":"2008","journal-title":"Med. Int. Mex."},{"key":"C4FO00610K-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.jchromb.2013.10.013","volume":"942\u2013943","author":"Rodriguez-Sanchez","year":"2013","journal-title":"J. Chromatogr., B: Biomed. Appl."},{"issue":"9","key":"C4FO00610K-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3371","DOI":"10.1021\/ac062397g","volume":"79","author":"Berthod","year":"2007","journal-title":"Anal. Chem."},{"issue":"30","key":"C4FO00610K-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7403","DOI":"10.1021\/jf401407s","volume":"61","author":"Rodriguez-Sanchez","year":"2013","journal-title":"J. Agric. Food Chem."},{"issue":"9","key":"C4FO00610K-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/0039-128X(93)90079-3","volume":"58","author":"De la Pe\u00f1a","year":"1993","journal-title":"Steroids"},{"key":"C4FO00610K-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"647620","DOI":"10.1155\/2012\/647620","volume":"2012","author":"Falkenberg","year":"2012","journal-title":"Evid. Based Complement. Alternat. Med."},{"issue":"1\u20132","key":"C4FO00610K-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0960-0760(00)00053-4","volume":"73","author":"Jaimez","year":"2000","journal-title":"J. Steroid Biochem. Mol. Biol."},{"issue":"3","key":"C4FO00610K-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1021\/np960487i","volume":"60","author":"Gu","year":"1997","journal-title":"J. Nat. Prod."},{"issue":"2","key":"C4FO00610K-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0031-9422(00)00055-8","volume":"54","author":"Domergue","year":"2000","journal-title":"Phytochemistry"},{"issue":"24","key":"C4FO00610K-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"12906","DOI":"10.1021\/jf103848p","volume":"58","author":"Degenhardt","year":"2010","journal-title":"J. Agric. Food Chem."},{"issue":"5","key":"C4FO00610K-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1021\/jf990977r","volume":"48","author":"Kim","year":"2000","journal-title":"J. Agric. Food Chem."},{"issue":"5","key":"C4FO00610K-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1021\/jf0015120","volume":"49","author":"Kawagishi","year":"2001","journal-title":"J. Agric. Food Chem."},{"issue":"12","key":"C4FO00610K-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1161\/ATVBAHA.110.207522","volume":"30","author":"Li","year":"2010","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"4","key":"C4FO00610K-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s00059-008-3132-2","volume":"33","author":"Weber","year":"2008","journal-title":"Herz"},{"issue":"10","key":"C4FO00610K-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1161\/01.CIR.101.10.1206","volume":"101","author":"Awtry","year":"2000","journal-title":"Circulation"},{"issue":"1","key":"C4FO00610K-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S0300-8932(10)70010-5","volume":"63","author":"Angiolillo","year":"2010","journal-title":"Rev. Esp. Cardiol."},{"issue":"12","key":"C4FO00610K-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/S0167-7799(02)02080-2","volume":"20","author":"Raskin","year":"2002","journal-title":"Trends Biotechnol."},{"issue":"4","key":"C4FO00610K-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.thromres.2011.04.023","volume":"128","author":"Cohen","year":"2011","journal-title":"Thromb. Res."},{"issue":"2","key":"C4FO00610K-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1021\/cb900266r","volume":"5","author":"Chen","year":"2010","journal-title":"ACS Chem. Biol."},{"issue":"2","key":"C4FO00610K-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0049-3848(02)00087-7","volume":"106","author":"Mandic","year":"2002","journal-title":"Thromb. Res."},{"issue":"4","key":"C4FO00610K-(cit30)\/*[position()=1]","first-page":"461","volume":"3","author":"Karagkiozaki","year":"2008","journal-title":"Int. J. Nanomedicine"},{"issue":"7","key":"C4FO00610K-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2615","DOI":"10.1182\/blood.V90.7.2615","volume":"90","author":"Heemskerk","year":"1997","journal-title":"Blood"},{"issue":"19","key":"C4FO00610K-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"19421","DOI":"10.1074\/jbc.M308864200","volume":"279","author":"Roberts","year":"2004","journal-title":"J. Biol. Chem."},{"issue":"2","key":"C4FO00610K-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1182\/blood.V63.2.439.439","volume":"63","author":"Yamazaki","year":"1984","journal-title":"Blood"},{"issue":"5","key":"C4FO00610K-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1172\/JCI109032","volume":"61","author":"Coller","year":"1978","journal-title":"J. Clin. Invest."},{"issue":"12","key":"C4FO00610K-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.2174\/1385272003375789","volume":"4","author":"Rodriguez-Saona","year":"2000","journal-title":"Curr. Org. Chem."},{"issue":"4","key":"C4FO00610K-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/s10863-012-9452-1","volume":"44","author":"Silva-Platas","year":"2012","journal-title":"J. Bioenerg. Biomembr."},{"key":"C4FO00610K-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.theochem.2008.08.029","volume":"869","author":"Mendoza-Wilson","year":"2008","journal-title":"J. Mol. Struct."},{"key":"C4FO00610K-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1159\/000073792","volume":"92","author":"de Lorgeril","year":"2003","journal-title":"World Rev. Nutr. Diet."},{"key":"C4FO00610K-(cit39)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/j.1365-2796.1989.tb01448.x","volume":"731","author":"Kristensen","year":"1989","journal-title":"J. Intern. Med. Suppl."},{"issue":"8","key":"C4FO00610K-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/0006-2952(96)00473-X","volume":"52","author":"Kramer","year":"1996","journal-title":"Biochem. Pharmacol."},{"issue":"2 Suppl","key":"C4FO00610K-(cit41)\/*[position()=1]","first-page":"19","volume":"29","author":"Yuhki","year":"2010","journal-title":"Int. Angiol."},{"issue":"6 Pt 2","key":"C4FO00610K-(cit42)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1161\/01.HYP.15.6.699","volume":"15","author":"Auch-Schwelk","year":"1990","journal-title":"Hypertension"},{"issue":"12","key":"C4FO00610K-(cit43)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1016\/j.bbalip.2010.08.002","volume":"1801","author":"Bannenberg","year":"2010","journal-title":"Biochim. Biophys. Acta"},{"key":"C4FO00610K-(cit44)\/*[position()=1]","first-page":"13","volume":"4","author":"Hong","year":"2013","journal-title":"Front Immunol."},{"issue":"10","key":"C4FO00610K-(cit45)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1161\/ATVBAHA.110.209908","volume":"30","author":"Fredman","year":"2010","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"C4FO00610K-(cit46)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0048-4059(83)81008-X","volume":"22","author":"Prusky","year":"1983","journal-title":"Physiol. Plant. Pathol."},{"issue":"4","key":"C4FO00610K-(cit47)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s00403-010-1088-6","volume":"303","author":"Rosenblat","year":"2011","journal-title":"Arch. Dermatol. Res."},{"issue":"1\u20133","key":"C4FO00610K-(cit48)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.ejphar.2011.09.184","volume":"672","author":"Otuki","year":"2011","journal-title":"Eur. J. Pharmacol."},{"issue":"5","key":"C4FO00610K-(cit49)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1002\/nt.2620030504","volume":"3","author":"Oelrichs","year":"1995","journal-title":"Nat. Toxins"},{"issue":"4","key":"C4FO00610K-(cit50)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1253\/circj.CJ-09-0982","volume":"74","author":"Angiolillo","year":"2010","journal-title":"Circ. J."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2015\/FO\/C4FO00610K","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T18:27:22Z","timestamp":1782930442000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/6\/1\/192-202\/438855"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.1039\/c4fo00610k","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Gerardo Garc\u00eda-Rivas (ResearcherID)","URL":"http:\/\/www.researcherid.com\/rid\/A-9691-2011","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"The Royal Society of Chemistry has an exclusive publication licence for this journal","name":"copyright_licence","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"The accepted version of this article will be made freely available after a 12 month embargo period","name":"copyright_licence","label":"OPEN ACCESS","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 13 July 2014; Accepted 22 September 2014; Accepted Manuscript published 23 September 2014; Advance Article published 16 October 2014; Version of Record published 24 December 2014","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}