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Chem."],"abstract":"<p>\n                    A series of 6-substituted 2-benzoxathiine-2,2-dioxides were synthesized starting from 2,5-dihydroxybenzaldehyde, and then screened\n                    <italic>in vitro<\/italic>\n                    for their inhibition properties against five human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms.\n                  <\/p>","DOI":"10.1039\/c4ob02155j","type":"journal-article","created":{"date-parts":[[2014,10,27]],"date-time":"2014-10-27T11:02:50Z","timestamp":1414407770000},"page":"77-80","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["6-Substituted 1,2-benzoxathiine-2,2-dioxides are isoform-selective inhibitors of human carbonic anhydrases IX, XII and VA"],"prefix":"10.1039","volume":"13","author":[{"given":"Muhammet","family":"Tanc","sequence":"first","affiliation":[{"name":"Universit\u00e0 degli Studi di Firenze"},{"name":"NEUROFARBA Department"},{"name":"Section of Pharmaceutical Chemistry"},{"name":"50019 Sesto Fiorentino (Florence)"},{"name":"Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"Carta","sequence":"additional","affiliation":[{"name":"Universit\u00e0 degli Studi di Firenze"},{"name":"Polo Scientifico"},{"name":"Laboratorio di Chimica Bioinorganica"},{"name":"50019 Sesto Fiorentino (Florence)"},{"name":"Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Scozzafava","sequence":"additional","affiliation":[{"name":"Universit\u00e0 degli Studi di Firenze"},{"name":"Polo Scientifico"},{"name":"Laboratorio di Chimica Bioinorganica"},{"name":"50019 Sesto Fiorentino (Florence)"},{"name":"Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudiu T.","family":"Supuran","sequence":"additional","affiliation":[{"name":"Universit\u00e0 degli Studi di Firenze"},{"name":"NEUROFARBA Department"},{"name":"Section of Pharmaceutical Chemistry"},{"name":"50019 Sesto Fiorentino (Florence)"},{"name":"Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2015]]},"reference":[{"key":"C4OB02155J-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1021\/jm301625s","volume":"56","author":"Tars","year":"2013","journal-title":"J. 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