{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T21:59:24Z","timestamp":1787003964244,"version":"build-2736575974"},"reference-count":25,"publisher":"Royal Society of Chemistry (RSC)","issue":"11","content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Org. Biomol. Chem."],"abstract":"<p>\n                    With the aid of an unexpected new multicomponent reaction 2,5-dihydro-1,3-thiazole\n                    <italic>S<\/italic>\n                    -monoxides can be converted to cyclic \u03b1-alkoxy isothioureas. In addition, an observed rearrangement of subsequently acylated isothioureas is described.\n                  <\/p>","DOI":"10.1039\/c4ob02608j","type":"journal-article","created":{"date-parts":[[2015,1,16]],"date-time":"2015-01-16T07:02:07Z","timestamp":1421391727000},"page":"3341-3346","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["A new multicomponent reaction: unexpected formation of derivatizable cyclic \u03b1-alkoxy isothioureas"],"prefix":"10.1039","volume":"13","author":[{"given":"Fabian","family":"Brockmeyer","sequence":"first","affiliation":[{"name":"Institut f\u00fcr Chemie"},{"name":"Carl von Ossietzky Universit\u00e4t Oldenburg"},{"name":"26111 Oldenburg"},{"name":"Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentin","family":"Morosow","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Chemie"},{"name":"Carl von Ossietzky Universit\u00e4t Oldenburg"},{"name":"26111 Oldenburg"},{"name":"Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Martens","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Chemie"},{"name":"Carl von Ossietzky Universit\u00e4t Oldenburg"},{"name":"26111 Oldenburg"},{"name":"Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2015]]},"reference":[{"key":"C4OB02608J-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6116","DOI":"10.1002\/ange.200700904","volume":"119","author":"Keim","year":"2007","journal-title":"Angew. Chem."},{"key":"C4OB02608J-(cit2a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1002\/ange.19931050440","volume":"105","author":"D\u00f6mling","year":"1993","journal-title":"Angew. Chem."},{"key":"C4OB02608J-(cit2b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3603","DOI":"10.1021\/jf970066m","volume":"45","author":"Elmore","year":"1997","journal-title":"J. Agric. Food Chem."},{"key":"C4OB02608J-(cit2c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"107","DOI":"10.3891\/acta.chem.scand.52-0107","volume":"52","author":"D\u00f6mling","year":"1998","journal-title":"Acta Chem. Scand."},{"key":"C4OB02608J-(cit2d)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1016\/S0040-4039(00)02321-2","volume":"42","author":"Fernandez","year":"2001","journal-title":"Tetrahedron Lett."},{"key":"C4OB02608J-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1002\/ange.19560681209","volume":"68","author":"Asinger","year":"1956","journal-title":"Angew. Chem."},{"key":"C4OB02608J-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1002\/ange.19810930808","volume":"93","author":"Martens","year":"1981","journal-title":"Angew. Chem."},{"key":"C4OB02608J-(cit5a)\/*[position()=1]","volume-title":"The chemistry of the carbon-nitrogen double bond","author":"Harada","year":"1992","unstructured":"K.\n              Harada\n            , in The chemistry of the carbon-nitrogen double bond, ed. S. Patai, John Wiley & Sons, London, 1992, ch. 6, pp. 255\u2013298"},{"key":"C4OB02608J-(cit5b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3089","DOI":"10.1021\/ja973872i","volume":"120","author":"Gr\u00f6ger","year":"1998","journal-title":"J. Am. Chem. Soc."},{"key":"C4OB02608J-(cit5c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/S0957-4166(99)00506-6","volume":"11","author":"Sail","year":"2000","journal-title":"Tetrahedron: Asymmetry"},{"key":"C4OB02608J-(cit5d)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.5560\/znb.2012-0146","volume":"67","author":"Stalling","year":"2012","journal-title":"Z. Naturforsch., B: Chem. Sci."},{"key":"C4OB02608J-(cit5e)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1002\/macp.201300716","volume":"215","author":"Sehlinger","year":"2014","journal-title":"Macromol. Chem. Phys."},{"key":"C4OB02608J-(cit6a)\/*[position()=1]","first-page":"386","volume":"71","author":"Ugi","year":"1959","journal-title":"Angew. Chem."},{"key":"C4OB02608J-(cit6b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1002\/ange.19620740103","volume":"74","author":"Ugi","year":"1962","journal-title":"Angew. Chem."},{"key":"C4OB02608J-(cit6c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1002\/cber.19620950123","volume":"95","author":"Ugi","year":"1962","journal-title":"Chem. Ber."},{"key":"C4OB02608J-(cit7a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1055\/s-1992-26240","author":"Kintscher","year":"1992","journal-title":"Synthesis"},{"key":"C4OB02608J-(cit7b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1080\/00397919508015852","volume":"25","author":"Hatam","year":"1995","journal-title":"Synth. Commun."},{"key":"C4OB02608J-(cit7c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1002\/hlca.201200441","volume":"95","author":"Brockmeyer","year":"2012","journal-title":"Helv. Chim. Acta"},{"key":"C4OB02608J-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.1002\/cssc.201402310","volume":"7","author":"Brockmeyer","year":"2014","journal-title":"ChemSusChem"},{"key":"C4OB02608J-(cit9a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1271\/bbb.58.1206","volume":"58","author":"Hirashima","year":"1994","journal-title":"Biosci., Biotechnol., Biochem."},{"key":"C4OB02608J-(cit9b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1007\/BF02290757","volume":"33","author":"Ambartsumova","year":"1997","journal-title":"Chem. Heterocycl. Compd."},{"key":"C4OB02608J-(cit9d)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4030","DOI":"10.1016\/j.bmcl.2007.04.093","volume":"17","author":"Kai","year":"2007","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"C4OB02608J-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1002\/jlac.198519850303","author":"Drauz","year":"1985","journal-title":"Liebigs Ann. Chem."},{"key":"C4OB02608J-(cit12)\/*[position()=2]","doi-asserted-by":"crossref","first-page":"6793","DOI":"10.1021\/jo100907u","volume":"75","author":"Niphakis","year":"2010","journal-title":"J. Org. Chem."},{"key":"C4OB02608J-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1002\/cber.19701030319","volume":"103","author":"K\u00f6nig","year":"1997","journal-title":"Chem. Ber."}],"container-title":["Organic &amp; Biomolecular Chemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2015\/OB\/C4OB02608J","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T17:32:40Z","timestamp":1782927160000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/ob\/article\/13\/11\/3341-3346\/445734"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":25,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.1039\/c4ob02608j","relation":{},"ISSN":["1477-0520","1477-0539"],"issn-type":[{"value":"1477-0520","type":"print"},{"value":"1477-0539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Supplementary Information","URL":"https:\/\/doi.org\/10.1039\/C4OB02608J","name":"related_data","group":{"name":"related_data","label":"RELATED DATA"}},{"value":"Crystal Structure Data","URL":"http:\/\/xlink.rsc.org?ccdc=true&msid=C4OB02608J","name":"related_data"},{"value":"The Royal Society of Chemistry has an exclusive publication licence for this journal","name":"copyright_licence","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"This article is freely available. This article is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported Licence (CC BY-NC 3.0)","URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/","name":"copyright_licence","label":"OPEN ACCESS","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 15 December 2014; Accepted 16 January 2015;  Accepted Manuscript published 16 January 2015;  Advance Article published 6 February 2015;  Version of Record published 4 March 2015","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}