{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T07:11:50Z","timestamp":1790838710540,"version":"4.1.0"},"reference-count":28,"publisher":"Royal Society of Chemistry (RSC)","issue":"16","content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Analyst"],"abstract":"<p>A new and simple design of a fully automated dual-online ultra-high pressure liquid chromatography system for high throughput deep proteome profiling and high throughput MRM experiments.<\/p>","DOI":"10.1039\/c5an00639b","type":"journal-article","created":{"date-parts":[[2015,6,19]],"date-time":"2015-06-19T06:01:12Z","timestamp":1434693672000},"page":"5700-5706","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["A simple dual online ultra-high pressure liquid chromatography system (sDO-UHPLC) for high throughput proteome analysis"],"prefix":"10.1039","volume":"140","author":[{"given":"Hangyeore","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Chemistry"},{"name":"Research Institute for Natural Sciences"},{"name":"Korea University"},{"name":"Seoul 136-701"},{"name":"South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Gi","family":"Mun","sequence":"additional","affiliation":[{"name":"Department of Chemistry"},{"name":"Research Institute for Natural Sciences"},{"name":"Korea University"},{"name":"Seoul 136-701"},{"name":"South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingi","family":"Bae","sequence":"additional","affiliation":[{"name":"Department of Chemistry"},{"name":"Research Institute for Natural Sciences"},{"name":"Korea University"},{"name":"Seoul 136-701"},{"name":"South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hokeun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Chemistry"},{"name":"Research Institute for Natural Sciences"},{"name":"Korea University"},{"name":"Seoul 136-701"},{"name":"South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Se Yeon","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Chemistry"},{"name":"Research Institute for Natural Sciences"},{"name":"Korea University"},{"name":"Seoul 136-701"},{"name":"South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Soo","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Pathology"},{"name":"University of Ulsan College of Medicine"},{"name":"Asan Medical Center"},{"name":"Seoul 138-873"},{"name":"South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae-Hyuk","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pathology"},{"name":"Chonnam National University Medical School"},{"name":"Gwangju 501-746"},{"name":"South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang-Won","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Chemistry"},{"name":"Research Institute for Natural Sciences"},{"name":"Korea University"},{"name":"Seoul 136-701"},{"name":"South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2015]]},"reference":[{"key":"C5AN00639B-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1038\/nature06916","volume":"452","author":"Hanash","year":"2008","journal-title":"Nature"},{"key":"C5AN00639B-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.4161\/cbt.8.12.8634","volume":"8","author":"Wang","year":"2009","journal-title":"Cancer Biol. Ther."},{"key":"C5AN00639B-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2343","DOI":"10.1021\/cr3003533","volume":"113","author":"Zhang","year":"2013","journal-title":"Chem. Rev."},{"key":"C5AN00639B-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1038\/nbt1235","volume":"24","author":"Rifai","year":"2006","journal-title":"Nat. Biotechnol."},{"key":"C5AN00639B-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1021\/pr1008515","volume":"10","author":"Surinova","year":"2011","journal-title":"J. Proteome Res."},{"key":"C5AN00639B-(cit6)\/*[position()=1]","first-page":"1386","volume":"2","author":"Paulovich","year":"2008","journal-title":"Proteomics: Clin. Appl."},{"key":"C5AN00639B-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.bbapap.2014.09.006","volume":"1854","author":"Drabovich","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"key":"C5AN00639B-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1002\/pmic.201100436","volume":"12","author":"Shi","year":"2012","journal-title":"Proteomics"},{"key":"C5AN00639B-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2699","DOI":"10.1021\/ac103243t","volume":"83","author":"K\u00f6cher","year":"2011","journal-title":"Anal. Chem."},{"key":"C5AN00639B-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.cell.2009.05.051","volume":"138","author":"Picotti","year":"2009","journal-title":"Cell"},{"key":"C5AN00639B-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1039\/c0an00105h","volume":"135","author":"Parker","year":"2010","journal-title":"Analyst"},{"key":"C5AN00639B-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1038\/nbt.1905","volume":"29","author":"Bisson","year":"2011","journal-title":"Nat. Biotechnol."},{"key":"C5AN00639B-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/j.bbapap.2013.06.008","volume":"1844","author":"Percy","year":"2014","journal-title":"Biochim. Biophys. Acta"},{"key":"C5AN00639B-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3353","DOI":"10.1021\/pr400178v","volume":"12","author":"Shi","year":"2013","journal-title":"J. Proteome Res."},{"key":"C5AN00639B-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9196","DOI":"10.1021\/ac402105s","volume":"85","author":"Shi","year":"2013","journal-title":"Anal. Chem."},{"key":"C5AN00639B-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1002\/elps.200600501","volume":"28","author":"Min","year":"2007","journal-title":"Electrophoresis"},{"key":"C5AN00639B-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1021\/ac701727r","volume":"80","author":"Livesay","year":"2008","journal-title":"Anal. Chem."},{"key":"C5AN00639B-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2743","DOI":"10.1021\/pr700876g","volume":"7","author":"Wang","year":"2008","journal-title":"J. Proteome Res."},{"key":"C5AN00639B-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5963","DOI":"10.1021\/pr400738a","volume":"12","author":"Orton","year":"2013","journal-title":"J. Proteome Res."},{"key":"C5AN00639B-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.chroma.2013.12.084","volume":"1329","author":"Lee","year":"2014","journal-title":"J. Chromatogr., A"},{"key":"C5AN00639B-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1002\/pmic.201000722","volume":"11","author":"Wang","year":"2011","journal-title":"Proteomics"},{"key":"C5AN00639B-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4373","DOI":"10.1021\/pr3004166","volume":"11","author":"Lee","year":"2012","journal-title":"J. Proteome Res."},{"key":"C5AN00639B-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.1039\/c0an00724b","volume":"136","author":"Hyung","year":"2011","journal-title":"Analyst"},{"key":"C5AN00639B-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1093\/bioinformatics\/btq054","volume":"26","author":"MacLean","year":"2010","journal-title":"Bioinformatics"},{"key":"C5AN00639B-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1074\/mcp.M700419-MCP200","volume":"7","author":"Shin","year":"2008","journal-title":"Mol. Cell. Proteomics"},{"key":"C5AN00639B-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5277","DOI":"10.1038\/ncomms6277","volume":"5","author":"Kim","year":"2014","journal-title":"Nat. Commun."},{"issue":"Suppl 16","key":"C5AN00639B-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1186\/1471-2105-13-S16-S2","volume":"13","author":"Jeong","year":"2012","journal-title":"BMC Bioinf."},{"key":"C5AN00639B-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/nature13438","volume":"513","author":"Zhang","year":"2014","journal-title":"Nature"}],"container-title":["The Analyst"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2015\/AN\/C5AN00639B","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T06:23:25Z","timestamp":1782887005000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/an\/article\/140\/16\/5700-5706\/463985"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":28,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.1039\/c5an00639b","relation":{},"ISSN":["0003-2654","1364-5528"],"issn-type":[{"value":"0003-2654","type":"print"},{"value":"1364-5528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Supplementary Information","URL":"https:\/\/doi.org\/10.1039\/C5AN00639B","name":"related_data","group":{"name":"related_data","label":"RELATED DATA"}},{"value":"The Royal Society of Chemistry has an exclusive publication licence for this journal","name":"copyright_licence","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"The accepted version of this article will be made freely available after a 12 month embargo period","name":"copyright_licence","label":"OPEN ACCESS","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 2 April 2015; Accepted 18 June 2015;  Accepted Manuscript published 19 June 2015;  Advance Article published 8 July 2015;  Version of Record published 27 July 2015","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}