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Commun."],"abstract":"<p>\n                    <italic>N<\/italic>\n                    ,\n                    <italic>O<\/italic>\n                    -Ligand\/Cu(OAc)\n                    <sub>2<\/sub>\n                    catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides to \u03b1-alkylidene succinimides is developed, affording dispiropyrrolidines in excellent diastereoselectivities and enantioselectivities.\n                  <\/p>","DOI":"10.1039\/c5cc02362a","type":"journal-article","created":{"date-parts":[[2015,4,28]],"date-time":"2015-04-28T07:00:21Z","timestamp":1430204421000},"page":"9212-9215","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":74,"title":["The copper-catalyzed asymmetric construction of a dispiropyrrolidine skeleton via 1,3-dipolar cycloaddition of azomethine ylides to \u03b1-alkylidene succinimides"],"prefix":"10.1039","volume":"51","author":[{"given":"Wu-Lin","family":"Yang","sequence":"first","affiliation":[{"name":"Shanghai Key Laboratory of New Drug Design"},{"name":"School of Pharmacy"},{"name":"East China University of Science and Technology"},{"name":"Shanghai 200237"},{"name":"People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang-Zi","family":"Liu","sequence":"additional","affiliation":[{"name":"Shanghai Key Laboratory of New Drug Design"},{"name":"School of Pharmacy"},{"name":"East China University of Science and Technology"},{"name":"Shanghai 200237"},{"name":"People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuai","family":"Luo","sequence":"additional","affiliation":[{"name":"Shanghai Key Laboratory of New Drug Design"},{"name":"School of Pharmacy"},{"name":"East China University of Science and Technology"},{"name":"Shanghai 200237"},{"name":"People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingxin","family":"Yu","sequence":"additional","affiliation":[{"name":"Shanghai Key Laboratory of New Drug Design"},{"name":"School of Pharmacy"},{"name":"East China University of Science and Technology"},{"name":"Shanghai 200237"},{"name":"People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John S.","family":"Fossey","sequence":"additional","affiliation":[{"name":"School of Chemistry"},{"name":"University of Birmingham"},{"name":"Birmingham"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Ping","family":"Deng","sequence":"additional","affiliation":[{"name":"Shanghai Key Laboratory of New Drug Design"},{"name":"School of Pharmacy"},{"name":"East China University of Science and Technology"},{"name":"Shanghai 200237"},{"name":"People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2015]]},"reference":[{"key":"C5CC02362A-(cit1)\/*[position()=1]","first-page":"84","volume-title":"The Alkaloids","year":"1973","unstructured":"The Alkaloids, ed. 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