{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T21:06:15Z","timestamp":1789938375696,"version":"4.0.1"},"reference-count":54,"publisher":"Royal Society of Chemistry (RSC)","issue":"2","content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<p>Piceatannol and pterostilbene both showed protective effect against A\u03b2-induced apoptosis in PC12 cells, however, with different PI3K\/Akt signaling pathways.<\/p>","DOI":"10.1039\/c5fo01124h","type":"journal-article","created":{"date-parts":[[2016,1,4]],"date-time":"2016-01-04T11:03:24Z","timestamp":1451905404000},"page":"1014-1023","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":92,"title":["Effects of piceatannol and pterostilbene against \u03b2-amyloid-induced apoptosis on the PI3K\/Akt\/Bad signaling pathway in PC12 cells"],"prefix":"10.1039","volume":"7","author":[{"given":"Zheng","family":"Fu","sequence":"first","affiliation":[{"name":"Center for Viticulture and Enology"},{"name":"College of Food Science and Nutritional Engineering"},{"name":"China Agricultural University"},{"name":"Beijing 100083"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiufang","family":"Yang","sequence":"additional","affiliation":[{"name":"Center for Viticulture and Enology"},{"name":"College of Food Science and Nutritional Engineering"},{"name":"China Agricultural University"},{"name":"Beijing 100083"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangji","family":"Wei","sequence":"additional","affiliation":[{"name":"Center for Viticulture and Enology"},{"name":"College of Food Science and Nutritional Engineering"},{"name":"China Agricultural University"},{"name":"Beijing 100083"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingming","family":"Li","sequence":"additional","affiliation":[{"name":"Center for Viticulture and Enology"},{"name":"College of Food Science and Nutritional Engineering"},{"name":"China Agricultural University"},{"name":"Beijing 100083"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2016]]},"reference":[{"key":"C5FO01124H-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.neuron.2004.09.010","volume":"44","author":"Walsh","year":"2004","journal-title":"Neuron"},{"key":"C5FO01124H-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1039\/c1fo00002k","volume":"2","author":"Hashimoto","year":"2011","journal-title":"Food Funct."},{"key":"C5FO01124H-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1007\/s11064-015-1550-0","volume":"40","author":"Cioanca","year":"2015","journal-title":"Neurochem. Res."},{"key":"C5FO01124H-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1007\/s12031-013-0063-z","volume":"51","author":"Yu","year":"2013","journal-title":"J. Mol. Neurosci."},{"key":"C5FO01124H-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1007\/s12031-015-0498-5","volume":"56","author":"Qian","year":"2015","journal-title":"J. Mol. Neurosci."},{"key":"C5FO01124H-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/s12017-011-8155-9","volume":"13","author":"Cai","year":"2011","journal-title":"NeuroMol. Med."},{"key":"C5FO01124H-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.etp.2012.05.003","volume":"65","author":"Guo","year":"2013","journal-title":"Exp. Toxicol. Pathol."},{"key":"C5FO01124H-(cit8)\/*[position()=1]","first-page":"163057","volume":"2013","author":"Xian","year":"2013","journal-title":"J. Evidence-Based Complementary Altern. Med."},{"key":"C5FO01124H-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6495","DOI":"10.1007\/s11033-012-1477-3","volume":"39","author":"Dong","year":"2012","journal-title":"Mol. Biol. Rep."},{"key":"C5FO01124H-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.exger.2013.02.025","volume":"48","author":"C","year":"2013","journal-title":"Exp. Gerontol."},{"key":"C5FO01124H-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.ejphar.2011.09.177","volume":"672","author":"Zeng","year":"2011","journal-title":"Eur. J. Pharmacol."},{"key":"C5FO01124H-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s00280-011-1699-4","volume":"69","author":"Liang","year":"2012","journal-title":"Cancer Chemother. Pharmacol."},{"key":"C5FO01124H-(cit13)\/*[position()=1]","volume-title":"Spotlight on Alzheimer's Disease","author":"Korol","year":"2012","unstructured":"T.\n            Korol\n          , Spotlight on Alzheimer's Disease, Thomson Reuters, 2012"},{"key":"C5FO01124H-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1039\/c4fo00068d","volume":"5","author":"Yang","year":"2014","journal-title":"Food Funct."},{"key":"C5FO01124H-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1039\/C5FO00055F","volume":"6","author":"Kim","year":"2015","journal-title":"Food Funct."},{"key":"C5FO01124H-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1039\/c2fo30075c","volume":"3","author":"Smid","year":"2012","journal-title":"Food Funct."},{"key":"C5FO01124H-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1021\/jf303843z","volume":"61","author":"Pawlus","year":"2013","journal-title":"J. Agric. Food Chem."},{"key":"C5FO01124H-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3441","DOI":"10.1016\/j.bmcl.2009.09.074","volume":"20","author":"Riviere","year":"2010","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"C5FO01124H-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.expneurol.2010.05.006","volume":"225","author":"Ho","year":"2010","journal-title":"Exp. Neurol."},{"key":"C5FO01124H-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1021\/cn400094w","volume":"4","author":"Singh","year":"2013","journal-title":"ACS Chem. Neurosci."},{"key":"C5FO01124H-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"e59888","DOI":"10.1371\/journal.pone.0059888","volume":"8","author":"Feng","year":"2013","journal-title":"PLoS One"},{"key":"C5FO01124H-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1038\/sj.bjp.0705688","volume":"141","author":"Han","year":"2004","journal-title":"Br. J. Pharmacol."},{"key":"C5FO01124H-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1016\/j.neurobiolaging.2011.08.015","volume":"33","author":"Chang","year":"2012","journal-title":"Neurobiol. Aging"},{"key":"C5FO01124H-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/j.1749-6632.2009.04727.x","volume":"1171","author":"Jang","year":"2009","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"C5FO01124H-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.jnutbio.2007.06.001","volume":"19","author":"Kim","year":"2008","journal-title":"J. Nutr. Biochem."},{"key":"C5FO01124H-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1196\/annals.1397.051","volume":"1095","author":"Kim","year":"2007","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"C5FO01124H-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/S0006-8993(98)01211-6","volume":"816","author":"Burke","year":"1999","journal-title":"Brain Res."},{"key":"C5FO01124H-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.neulet.2007.10.025","volume":"430","author":"Salins","year":"2008","journal-title":"Neurosci. Lett."},{"key":"C5FO01124H-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.neuroscience.2004.08.056","volume":"130","author":"Satoi","year":"2005","journal-title":"Neuroscience"},{"key":"C5FO01124H-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.neurobiolaging.2006.01.003","volume":"28","author":"Reix","year":"2007","journal-title":"Neurobiol. Aging"},{"key":"C5FO01124H-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1007\/s10571-013-9950-7","volume":"33","author":"Chen","year":"2013","journal-title":"Cell. Mol. Neurobiol."},{"key":"C5FO01124H-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1016\/j.molonc.2014.03.018","volume":"8","author":"Li","year":"2014","journal-title":"Mol. Oncol."},{"key":"C5FO01124H-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.toxicon.2011.11.003","volume":"59","author":"Du","year":"2012","journal-title":"Toxicon"},{"key":"C5FO01124H-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.chemphyslip.2014.05.003","volume":"183","author":"Gomez-Fernandez","year":"2014","journal-title":"Chem. Phys. Lipids"},{"key":"C5FO01124H-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/S0092-8674(00)81382-3","volume":"87","author":"Zha","year":"1996","journal-title":"Cell"},{"key":"C5FO01124H-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6739","DOI":"10.1021\/acs.jafc.5b01909","volume":"63","author":"Chen","year":"2015","journal-title":"J. Agric. Food Chem."},{"key":"C5FO01124H-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.theochem.2006.01.028","volume":"763","author":"Chen","year":"2006","journal-title":"J. Mol. Struct.: THEOCHEM"},{"key":"C5FO01124H-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3395","DOI":"10.1016\/j.tetlet.2008.03.130","volume":"49","author":"Parhi","year":"2008","journal-title":"Tetrahedron Lett."},{"key":"C5FO01124H-(cit39)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0304-3940(03)00075-2","volume":"340","author":"Xia","year":"2003","journal-title":"Neurosci. Lett."},{"key":"C5FO01124H-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s11010-010-0709-x","volume":"351","author":"Ola","year":"2011","journal-title":"Mol. Cell. Biochem."},{"key":"C5FO01124H-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/s12032-010-9431-5","volume":"28","author":"Zhang","year":"2011","journal-title":"Med. Oncol."},{"key":"C5FO01124H-(cit42)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1039\/C4FO01017E","volume":"6","author":"Huang","year":"2015","journal-title":"Food Funct."},{"key":"C5FO01124H-(cit43)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.ccr.2005.09.006","volume":"8","author":"She","year":"2005","journal-title":"Cancer Cell"},{"key":"C5FO01124H-(cit44)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1016\/j.bbrc.2013.11.010","volume":"441","author":"Ma","year":"2013","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"C5FO01124H-(cit45)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5868","DOI":"10.1038\/sj.onc.1208742","volume":"24","author":"Yamaguchi","year":"2005","journal-title":"Oncogene"},{"key":"C5FO01124H-(cit46)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4083","DOI":"10.1021\/jf205171g","volume":"60","author":"Ko","year":"2012","journal-title":"J. Agric. Food Chem."},{"key":"C5FO01124H-(cit47)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1111\/jphp.12360","volume":"67","author":"Song","year":"2015","journal-title":"J. Pharm. Pharmacol."},{"key":"C5FO01124H-(cit48)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1007\/s11164-012-1003-1","volume":"40","author":"Yuan","year":"2013","journal-title":"Res. Chem. Intermed."},{"key":"C5FO01124H-(cit49)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1593\/neo.04337","volume":"7","author":"Ferrer","year":"2005","journal-title":"Neoplasia"},{"key":"C5FO01124H-(cit50)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8537","DOI":"10.1021\/jf051985c","volume":"53","author":"Kim","year":"2005","journal-title":"J. Agric. Food Chem."},{"key":"C5FO01124H-(cit51)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/0092-8674(94)90131-7","volume":"77","author":"Behl","year":"1994","journal-title":"Cell"},{"key":"C5FO01124H-(cit52)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2486","DOI":"10.1039\/C4FO00476K","volume":"5","author":"Song","year":"2014","journal-title":"Food Funct."},{"key":"C5FO01124H-(cit53)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"10840","DOI":"10.1021\/jf102120c","volume":"58","author":"Huang","year":"2010","journal-title":"J. Agric. Food Chem."},{"key":"C5FO01124H-(cit54)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1021\/cn300143m","volume":"4","author":"Agrawal","year":"2013","journal-title":"ACS Chem. Neurosci."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2016\/FO\/C5FO01124H","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T18:24:33Z","timestamp":1783448673000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/7\/2\/1014-1023\/479965"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":54,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.1039\/c5fo01124h","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"The Royal Society of Chemistry has an exclusive publication licence for this journal","name":"copyright_licence","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"The accepted version of this article will be made freely available after a 12 month embargo period","name":"copyright_licence","label":"OPEN ACCESS","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 15 September 2015; Accepted 24 December 2015;  Accepted Manuscript published 4 January 2016;  Advance Article published 13 January 2016;  Version of Record published 17 February 2016","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}