{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T02:10:14Z","timestamp":1792894214130,"version":"4.5.0"},"reference-count":52,"publisher":"Oxford University Press (OUP)","issue":"10","funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["1U01 ES019458-01 to VMW and ZW, VW, SH and LC"],"award-info":[{"award-number":["1U01 ES019458-01 to VMW and ZW, VW, SH and LC"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["F31 CA183255 to LC"],"award-info":[{"award-number":["F31 CA183255 to LC"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01 CA138818-01A1 to VMW"],"award-info":[{"award-number":["R01 CA138818-01A1 to VMW"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01 CA174929 to VMW CP"],"award-info":[{"award-number":["R01 CA174929 to VMW CP"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["T32 CA108462-11 to ID"],"award-info":[{"award-number":["T32 CA108462-11 to ID"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["U54CA143836-01 to JL and VMW"],"award-info":[{"award-number":["U54CA143836-01 to JL and VMW"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"crossref","award":["1U01 ES019458-01 to VMW and ZW, VW, SH and LC"],"award-info":[{"award-number":["1U01 ES019458-01 to VMW and ZW, VW, SH and LC"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"crossref","award":["F31 CA183255 to LC"],"award-info":[{"award-number":["F31 CA183255 to LC"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"crossref","award":["R01 CA138818-01A1 to VMW"],"award-info":[{"award-number":["R01 CA138818-01A1 to VMW"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"crossref","award":["R01 CA174929 to VMW CP"],"award-info":[{"award-number":["R01 CA174929 to VMW CP"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"crossref","award":["T32 CA108462-11 to ID"],"award-info":[{"award-number":["T32 CA108462-11 to ID"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"crossref","award":["U54CA143836-01 to JL and VMW"],"award-info":[{"award-number":["U54CA143836-01 to JL and VMW"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2015,10,5]]},"DOI":"10.1039\/c5ib00040h","type":"journal-article","created":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T06:01:19Z","timestamp":1430460079000},"page":"1120-1134","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":1025,"title":["Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration"],"prefix":"10.1093","volume":"7","author":[{"given":"I.","family":"Acerbi","sequence":"first","affiliation":[{"name":"Center for Bioengineering, Tissue Regeneration, Department of Surgery, UCSF, San Francisco, CA, USA. Fax: +1-415-476-3985; Tel: +1-415-476-3826"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Cassereau","sequence":"additional","affiliation":[{"name":"Center for Bioengineering, Tissue Regeneration, Department of Surgery, UCSF, San Francisco, CA, USA. Fax: +1-415-476-3985; Tel: +1-415-476-3826"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Dean","sequence":"additional","affiliation":[{"name":"Center for Bioengineering, Tissue Regeneration, Department of Surgery, UCSF, San Francisco, CA, USA. Fax: +1-415-476-3985; Tel: +1-415-476-3826"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Q.","family":"Shi","sequence":"additional","affiliation":[{"name":"Bay Area Physical Sciences Oncology Center, USA"},{"name":"Department of Bioengineering, Stanford University, Palo Alto, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Au","sequence":"additional","affiliation":[{"name":"Department of Pathology, UCSF, San Francisco, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, UCSF, San Francisco, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y. Y.","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pathology, UCSF, San Francisco, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Liphardt","sequence":"additional","affiliation":[{"name":"Bay Area Physical Sciences Oncology Center, USA"},{"name":"Department of Bioengineering, Stanford University, Palo Alto, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. S.","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Surgery, Duke University Comprehensive Cancer Center, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V. M.","family":"Weaver","sequence":"additional","affiliation":[{"name":"Center for Bioengineering, Tissue Regeneration, Department of Surgery, UCSF, San Francisco, CA, USA. Fax: +1-415-476-3985; Tel: +1-415-476-3826"},{"name":"Bay Area Physical Sciences Oncology Center, USA"},{"name":"Departments of Anatomy and Bioengineering and Therapeutic Sciences, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, and UCSF Helen Diller Comprehensive Cancer Center, UCSF, San Francisco, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2015,5,11]]},"reference":[{"issue":"10","key":"key\n\t\t\t\t2019012509262192000_cit1","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.1016\/j.ultrasmedbio.2014.05.020","article-title":"Comparison of strain and shear wave elastography for the differentiation of benign from malignant breast lesions, combined with B-mode ultrasonography: qualitative and quantitative assessments","volume":"40","author":"Youk","year":"2014","journal-title":"Ultrasound Med. Biol."},{"issue":"1","key":"key\n\t\t\t\t2019012509262192000_cit2","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/s10549-011-1627-7","article-title":"Clinical application of shear wave elastography (SWE) in the diagnosis of benign and malignant breast diseases","volume":"129","author":"Chang","year":"2011","journal-title":"Breast Cancer Res. Treat."},{"issue":"3","key":"key\n\t\t\t\t2019012509262192000_cit3","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.ccr.2012.01.007","article-title":"Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma","volume":"21","author":"Provenzano","year":"2012","journal-title":"Cancer Cell"},{"issue":"3","key":"key\n\t\t\t\t2019012509262192000_cit4","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1073\/pnas.1118910109","article-title":"Mechanical compression drives cancer cells toward invasive phenotype","volume":"109","author":"Tse","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"6","key":"key\n\t\t\t\t2019012509262192000_cit5","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/j.ccr.2011.05.008","article-title":"Actomyosin-mediated cellular tension drives increased tissue stiffness and \u03b2-catenin activation to induce epidermal hyperplasia and tumor growth","volume":"19","author":"Samuel","year":"2011","journal-title":"Cancer Cell"},{"issue":"9","key":"key\n\t\t\t\t2019012509262192000_cit6","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1039\/c1ib00043h","article-title":"In situ force mapping of mammary gland transformation","volume":"3","author":"Lopez","year":"2011","journal-title":"Integr. Biol."},{"issue":"6","key":"key\n\t\t\t\t2019012509262192000_cit7","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1002\/jso.21709","article-title":"Tumor microenvironment and progression","volume":"103","author":"Dvorak","year":"2011","journal-title":"J. Surg. Oncol."},{"issue":"12","key":"key\n\t\t\t\t2019012509262192000_cit8","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a005058","article-title":"Extracellular matrix degradation and remodeling in development and disease","volume":"3","author":"Lu","year":"2011","journal-title":"Cold Spring Harbor Perspect. Biol."},{"issue":"5","key":"key\n\t\t\t\t2019012509262192000_cit9","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/j.cell.2009.10.027","article-title":"Matrix crosslinking forces tumor progression by enhancing integrin signaling","volume":"139","author":"Levental","year":"2009","journal-title":"Cell"},{"key":"key\n\t\t\t\t2019012509262192000_cit10","first-page":"S68","article-title":"Extracellular matrix remodeling and the regulation of epithelial-stromal interactions during differentiation and involution","volume":"54","author":"Werb","year":"1996","journal-title":"Kidney Int. Suppl."},{"issue":"3","key":"key\n\t\t\t\t2019012509262192000_cit11","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s10911-011-9226-0","article-title":"Mechanisms by which the extracellular matrix and integrin signaling act to regulate the switch between tumor suppression and tumor promotion","volume":"16","author":"Keely","year":"2011","journal-title":"J. Mammary Gland Biol. Neoplasia"},{"issue":"4","key":"key\n\t\t\t\t2019012509262192000_cit12","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1517\/14728222.2013.757305","article-title":"Tumor-stromal interactions in breast tumor progression\u2014significance of histological heterogeneity of tumor-stromal fibroblasts","volume":"17","author":"Hasebe","year":"2013","journal-title":"Expert Opin. Ther. Targets"},{"issue":"7","key":"key\n\t\t\t\t2019012509262192000_cit13","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1007\/s10585-012-9499-8","article-title":"Stromal biomarkers in breast cancer development and progression","volume":"29","author":"Rudnick","year":"2012","journal-title":"Clin. Exp. Metastasis"},{"issue":"17","key":"key\n\t\t\t\t2019012509262192000_cit14","doi-asserted-by":"crossref","first-page":"5336","DOI":"10.1158\/0008-5472.CAN-13-0012","article-title":"Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-\u03b2-deficient mouse mammary carcinomas","volume":"73","author":"Pickup","year":"2013","journal-title":"Cancer Res."},{"issue":"14","key":"key\n\t\t\t\t2019012509262192000_cit15","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1088\/0031-9155\/48\/14\/310","article-title":"Measuring the elastic modulus of ex vivo small tissue samples","volume":"48","author":"Samani","year":"2003","journal-title":"Phys. Med. Biol."},{"issue":"6","key":"key\n\t\t\t\t2019012509262192000_cit16","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1088\/0031-9155\/52\/6\/002","article-title":"Elastic moduli of normal and pathological human breast tissues: an inversion-technique-based investigation of 169 samples","volume":"52","author":"Samani","year":"2007","journal-title":"Phys. Med. Biol."},{"issue":"11","key":"key\n\t\t\t\t2019012509262192000_cit17","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1038\/nnano.2012.167","article-title":"The nanomechanical signature of breast cancer","volume":"7","author":"Plodinec","year":"2012","journal-title":"Nat. Nanotechnol."},{"issue":"3","key":"key\n\t\t\t\t2019012509262192000_cit18","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1016\/j.ajpath.2010.11.076","article-title":"Aligned collagen is a prognostic signature for survival in human breast carcinoma","volume":"178","author":"Conklin","year":"2011","journal-title":"Am. J. Pathol."},{"issue":"6","key":"key\n\t\t\t\t2019012509262192000_cit19","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1111\/j.1349-7006.1997.tb00423.x","article-title":"Fibrotic focus in invasive ductal carcinoma of the breast: a histopathological prognostic parameter for tumor recurrence and tumor death within three years after the initial operation","volume":"88","author":"Hasebe","year":"1997","journal-title":"Jpn. J. Cancer Res."},{"issue":"1","key":"key\n\t\t\t\t2019012509262192000_cit20","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s10585-008-9209-8","article-title":"Three-dimensional context regulation of metastasis","volume":"26","author":"Erler","year":"2009","journal-title":"Clin. Exp. Metastasis"},{"issue":"21","key":"key\n\t\t\t\t2019012509262192000_cit21","doi-asserted-by":"crossref","first-page":"10238","DOI":"10.1158\/0008-5472.CAN-06-3197","article-title":"Lysyl oxidase mediates hypoxic control of metastasis","volume":"66","author":"Erler","year":"2006","journal-title":"Cancer Res."},{"issue":"2","key":"key\n\t\t\t\t2019012509262192000_cit22","first-page":"143","article-title":"Lysyl oxidase-like protein localizes to sites of de novo fibrinogenesis in fibrosis and in the early stromal reaction of ductal breast carcinomas","volume":"78","author":"Decitre","year":"1998","journal-title":"Lab. Invest."},{"issue":"35","key":"key\n\t\t\t\t2019012509262192000_cit23","doi-asserted-by":"crossref","first-page":"4057","DOI":"10.1038\/onc.2012.578","article-title":"Cancer-stromal cell interactions mediated by hypoxia-inducible factors promote angiogenesis, lymphangiogenesis, and metastasis","volume":"32","author":"Semenza","year":"2013","journal-title":"Oncogene"},{"issue":"2","key":"key\n\t\t\t\t2019012509262192000_cit24","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1093\/jnci\/92.2.120","article-title":"Bcar1\/p130Cas protein and primary breast cancer: prognosis and response to tamoxifen treatment","volume":"92","author":"van der Flier","year":"2000","journal-title":"J. Natl. Cancer Inst."},{"issue":"2\u20133","key":"key\n\t\t\t\t2019012509262192000_cit25","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.ejcb.2010.09.002","article-title":"p130Cas promotes invasiveness of three-dimensional ErbB2-transformed mammary acinar structures by enhanced activation of mTOR\/p70S6K and Rac1","volume":"90","author":"Tornillo","year":"2011","journal-title":"Eur. J. Cell Biol."},{"issue":"3","key":"key\n\t\t\t\t2019012509262192000_cit26","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1053\/hupa.2003.40","article-title":"Focal adhesion kinase as a marker of malignant phenotype in breast and cervical carcinomas","volume":"34","author":"Oktay","year":"2003","journal-title":"Hum. Pathol."},{"issue":"1","key":"key\n\t\t\t\t2019012509262192000_cit27","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.bbrc.2005.12.164","article-title":"Role of c-Src and focal adhesion kinase in progression and metastasis of estrogen receptor-positive breast cancer","volume":"341","author":"Planas-Silva","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"23","key":"key\n\t\t\t\t2019012509262192000_cit28","doi-asserted-by":"crossref","first-page":"7219","DOI":"10.1158\/1078-0432.CCR-11-0642","article-title":"\u03b21-integrin: a potential therapeutic target in the battle against cancer recurrence","volume":"17","author":"Barkan","year":"2011","journal-title":"Clin. Cancer Res."},{"issue":"11\u201312","key":"key\n\t\t\t\t2019012509262192000_cit29","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1080\/09553000701639694","article-title":"beta1 integrin as a molecular therapeutic target","volume":"83","author":"Cordes","year":"2007","journal-title":"Int. J. Radiat. Biol."},{"issue":"7","key":"key\n\t\t\t\t2019012509262192000_cit30","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nmeth.2089","article-title":"NIH Image to ImageJ: 25 years of image analysis","volume":"9","author":"Schneider","year":"2012","journal-title":"Nat. Methods"},{"issue":"1","key":"key\n\t\t\t\t2019012509262192000_cit31","doi-asserted-by":"crossref","first-page":"016028","DOI":"10.1117\/1.3327280","article-title":"New, simple theory-based, accurate polarization microscope for birefringence imaging of biological cells","volume":"15","author":"Shin","year":"2010","journal-title":"J. Biomed. Opt."},{"issue":"1955","key":"key\n\t\t\t\t2019012509262192000_cit32","doi-asserted-by":"crossref","first-page":"2751","DOI":"10.1098\/rspa.1996.0145","article-title":"An Automatic Optical Imaging System for Birefringent Media","volume":"452","author":"Glazer","year":"1996","journal-title":"Proc. R. Soc. London, Ser. A"},{"issue":"2","key":"key\n\t\t\t\t2019012509262192000_cit33","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1073\/pnas.1311312110","article-title":"Rapid disorganization of mechanically interacting systems of mammary acini","volume":"111","author":"Shi","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"4","key":"key\n\t\t\t\t2019012509262192000_cit34","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1023\/A:1020802631968","article-title":"Specimen preparation and quantification of collagen birefringence in unstained sections of articular cartilage using image analysis and polarizing light microscopy","volume":"29","author":"Kir\u00e1ly","year":"1997","journal-title":"Histochem. J."},{"issue":"3","key":"key\n\t\t\t\t2019012509262192000_cit35","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.ccr.2005.08.010","article-title":"Tensional homeostasis and the malignant phenotype","volume":"8","author":"Paszek","year":"2005","journal-title":"Cancer Cell"},{"issue":"8","key":"key\n\t\t\t\t2019012509262192000_cit36","doi-asserted-by":"crossref","first-page":"2796","DOI":"10.1073\/pnas.1104303108","article-title":"Leukocyte composition of human breast cancer","volume":"109","author":"Ruffell","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"5","key":"key\n\t\t\t\t2019012509262192000_cit37","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.ccell.2014.09.006","article-title":"Macrophage IL-10 blocks CD8+T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells","volume":"26","author":"Ruffell","year":"2014","journal-title":"Cancer Cell"},{"issue":"3","key":"key\n\t\t\t\t2019012509262192000_cit38","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1189\/jlb.1107762","article-title":"Macrophages define the invasive microenvironment in breast cancer","volume":"84","author":"Pollard","year":"2008","journal-title":"J. Leukocyte Biol."},{"issue":"11","key":"key\n\t\t\t\t2019012509262192000_cit39","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1038\/nrc3603","article-title":"The roles of TGF\u03b2 in the tumour microenvironment","volume":"13","author":"Pickup","year":"2013","journal-title":"Nat. Rev. Cancer"},{"key":"key\n\t\t\t\t2019012509262192000_cit40","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1002\/(SICI)1097-4644(1998)72:30\/31+<111::AID-JCB15>3.0.CO;2-5","article-title":"Signal transduction by transforming growth factor-beta: a cooperative paradigm with extensive negative regulation","volume":"30\u201331","author":"Engel","year":"1998","journal-title":"J. Cell. Biochem."},{"issue":"8","key":"key\n\t\t\t\t2019012509262192000_cit41","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1093\/annonc\/mdr304","article-title":"Panel members, Strategies for subtypes\u2014dealing with the diversity of breast cancer: highlights of the St. Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer","volume":"22","author":"Goldhirsch","year":"2011","journal-title":"Ann. Oncol."},{"issue":"3","key":"key\n\t\t\t\t2019012509262192000_cit42","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.diff.2013.07.004","article-title":"From tissue mechanics to transcription factors","volume":"86","author":"Janmey","year":"2013","journal-title":"Differentiation"},{"issue":"7","key":"key\n\t\t\t\t2019012509262192000_cit43","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1038\/nrm3136","article-title":"Mechanotransduction: YAP and TAZ feel the force","volume":"12","author":"Wrighton","year":"2011","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"16","key":"key\n\t\t\t\t2019012509262192000_cit44","doi-asserted-by":"crossref","first-page":"2663","DOI":"10.1016\/j.febslet.2014.04.012","article-title":"YAP\/TAZ as mechanosensors and mechanotransducers in regulating organ size and tumor growth","volume":"588","author":"Low","year":"2014","journal-title":"FEBS Lett."},{"issue":"6","key":"key\n\t\t\t\t2019012509262192000_cit45","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1358\/mf.2002.24.6.693065","article-title":"Transforming growth factor-beta 1-induced collagen production in cultures of cardiac fibroblasts is the result of the appearance of myofibroblasts","volume":"24","author":"Lijnen","year":"2002","journal-title":"Methods Find. Exp. Clin. Pharmacol."},{"issue":"3","key":"key\n\t\t\t\t2019012509262192000_cit46","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.ejrad.2006.08.002","article-title":"Influence of mammographic density on the diagnostic accuracy of tumor size assessment and association with breast cancer tumor characteristics","volume":"60","author":"Fasching","year":"2006","journal-title":"Eur. J. Radiol."},{"issue":"9","key":"key\n\t\t\t\t2019012509262192000_cit47","doi-asserted-by":"crossref","first-page":"2450","DOI":"10.1007\/s00330-013-2866-2","article-title":"Stiffness of tumours measured by shear-wave elastography correlated with subtypes of breast cancer","volume":"23","author":"Chang","year":"2013","journal-title":"Eur. J. Radiol."},{"issue":"6","key":"key\n\t\t\t\t2019012509262192000_cit48","doi-asserted-by":"crossref","first-page":"R104","DOI":"10.1186\/bcr2787","article-title":"Quantitative shear wave ultrasound elastography: initial experience in solid breast masses","volume":"12","author":"Evans","year":"2010","journal-title":"Breast Cancer Res."},{"issue":"4","key":"key\n\t\t\t\t2019012509262192000_cit49","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1038\/nm.3497","article-title":"Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression","volume":"20","author":"Mouw","year":"2014","journal-title":"Nat. Med."},{"issue":"49","key":"key\n\t\t\t\t2019012509262192000_cit50","doi-asserted-by":"crossref","first-page":"4326","DOI":"10.1038\/onc.2009.299","article-title":"Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK-ERK linkage","volume":"28","author":"Provenzano","year":"2009","journal-title":"Oncogene"},{"issue":"3","key":"key\n\t\t\t\t2019012509262192000_cit51","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.ejrad.2012.03.001","article-title":"Breast elasticity: principles, technique, results: an update and overview of commercially available software","volume":"82","author":"Balleyguier","year":"2013","journal-title":"Eur. J. Radiol."},{"issue":"1","key":"key\n\t\t\t\t2019012509262192000_cit52","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.ccell.2014.12.001","article-title":"Biological and Therapeutic Impact of Intratumor Heterogeneity in Cancer Evolution","volume":"27","author":"McGranahan","year":"2015","journal-title":"Cancer Cell"}],"container-title":["Integrative Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ib\/article-pdf\/7\/10\/1120\/27281796\/c5ib00040h.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,24]],"date-time":"2019-08-24T07:36:46Z","timestamp":1566632206000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ib\/article\/7\/10\/1120\/5198292"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,11]]},"references-count":52,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2015,5,11]]},"published-print":{"date-parts":[[2015,10,5]]}},"URL":"https:\/\/doi.org\/10.1039\/c5ib00040h","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.725485692.793517744","asserted-by":"object"}]},"ISSN":["1757-9708"],"issn-type":[{"value":"1757-9708","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2015,10]]},"published":{"date-parts":[[2015,5,11]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"The Royal Society of Chemistry has an exclusive publication licence for this journal","name":"copyright_licence","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 7 February 2015; Accepted 1 May 2015; Accepted Manuscript published 1 May 2015; Advance Article published 11 May 2015; Version of Record published 5 October 2015","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}