{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T06:58:58Z","timestamp":1782889138498,"version":"3.54.5"},"reference-count":34,"publisher":"Royal Society of Chemistry (RSC)","issue":"1","funder":[{"DOI":"10.13039\/501100000582","name":"Carnegie Trust for the Universities of Scotland","doi-asserted-by":"crossref","award":["Jonathan Simpson"],"award-info":[{"award-number":["Jonathan Simpson"]}],"id":[{"id":"10.13039\/501100000582","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Nanoscale Horiz."],"abstract":"<p>Cholera toxin B subunit (CTB) is detected sensitively in samples of synthetic freshwater by measuring changes in the SERS intensity of the glyconanoparticles upon their binding of CTB and subsequently aggregating. The particles are coated in both galactose and sialic acid.<\/p>","DOI":"10.1039\/c5nh00036j","type":"journal-article","created":{"date-parts":[[2015,11,20]],"date-time":"2015-11-20T12:00:34Z","timestamp":1448020834000},"page":"60-63","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Mixed-monolayer glyconanoparticles for the detection of cholera toxin by surface enhanced Raman spectroscopy"],"prefix":"10.1039","volume":"1","author":[{"given":"Jonathan","family":"Simpson","sequence":"first","affiliation":[{"name":"Centre for Molecular Nanometrology"},{"name":"Department of Pure and Applied Chemistry"},{"name":"University of Strathclyde (Technology and Innovation Centre)"},{"name":"Glasgow"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek","family":"Craig","sequence":"additional","affiliation":[{"name":"Optical Manipulation Group"},{"name":"SUPA"},{"name":"University of St. Andrews"},{"name":"St. Andrews"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Faulds","sequence":"additional","affiliation":[{"name":"Centre for Molecular Nanometrology"},{"name":"Department of Pure and Applied Chemistry"},{"name":"University of Strathclyde (Technology and Innovation Centre)"},{"name":"Glasgow"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duncan","family":"Graham","sequence":"additional","affiliation":[{"name":"Centre for Molecular Nanometrology"},{"name":"Department of Pure and Applied Chemistry"},{"name":"University of Strathclyde (Technology and Innovation Centre)"},{"name":"Glasgow"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2016]]},"reference":[{"key":"C5NH00036J-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5028","DOI":"10.1039\/C4TB00510D","volume":"2","author":"Steven","year":"2014","journal-title":"J. Mater. Chem. B"},{"key":"C5NH00036J-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/S1028-4559(08)60127-8","volume":"47","author":"Rojanathanes","year":"2008","journal-title":"Taiwan. J. Obstet. Gynecol."},{"key":"C5NH00036J-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2330","DOI":"10.1039\/C4AN02365J","volume":"140","author":"Jamieson","year":"2015","journal-title":"Analyst"},{"key":"C5NH00036J-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1021\/bc500035y","volume":"25","author":"Lesniewski","year":"2014","journal-title":"Bioconjugate Chem."},{"key":"C5NH00036J-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1038\/382607a0","volume":"382","author":"Mirkin","year":"1996","journal-title":"Nature"},{"key":"C5NH00036J-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1021\/ac0103468","volume":"74","author":"Zhang","year":"2001","journal-title":"Anal. Chem."},{"key":"C5NH00036J-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7141","DOI":"10.1021\/la034358v","volume":"19","author":"Hone","year":"2003","journal-title":"Langmuir"},{"key":"C5NH00036J-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4756","DOI":"10.1002\/anie.201205748","volume":"53","author":"Schl\u00fccker","year":"2014","journal-title":"Angew. Chem., Int. Ed."},{"key":"C5NH00036J-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1039\/a801289j","author":"Graham","year":"1998","journal-title":"Chem. Commun."},{"key":"C5NH00036J-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1021\/cr2001178","volume":"112","author":"Saha","year":"2012","journal-title":"Chem. Rev."},{"key":"C5NH00036J-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4388","DOI":"10.1021\/jp068253n","volume":"111","author":"Kumar","year":"2007","journal-title":"J. Phys. Chem. C"},{"key":"C5NH00036J-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1039\/b406423b","volume":"129","author":"Faulds","year":"2004","journal-title":"Analyst"},{"key":"C5NH00036J-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1039\/C2CC36949D","volume":"49","author":"Craig","year":"2013","journal-title":"Chem. Commun."},{"key":"C5NH00036J-(cit14)\/*[position()=1]","volume-title":"Modern Raman Spectroscopy: A Practical Approach","author":"Smith","year":"2005","unstructured":"E.\n            Smith\n           and G.Dent, Modern Raman Spectroscopy: A Practical Approach, John Wiley & Sons Ltd., Chichester, West Sussex, 1st edn, 2005"},{"key":"C5NH00036J-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1002\/ange.200604265","volume":"119","author":"Faulds","year":"2007","journal-title":"Angew. Chem."},{"key":"C5NH00036J-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7749","DOI":"10.1021\/es101228z","volume":"44","author":"Halvorson","year":"2010","journal-title":"Environ. Sci. Technol."},{"key":"C5NH00036J-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1021\/es801531t","volume":"43","author":"Rule","year":"2009","journal-title":"Environ. Sci. Technol."},{"key":"C5NH00036J-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1021\/ac061462j","volume":"79","author":"Schofield","year":"2007","journal-title":"Anal. Chem."},{"key":"C5NH00036J-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4358","DOI":"10.1039\/c2cs35427f","volume":"42","author":"Reichardt","year":"2013","journal-title":"Chem. Soc. Rev."},{"key":"C5NH00036J-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"15229","DOI":"10.1021\/ja306288p","volume":"134","author":"Gorityala","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"C5NH00036J-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4775","DOI":"10.1021\/ac4038762","volume":"86","author":"Craig","year":"2014","journal-title":"Anal. Chem."},{"key":"C5NH00036J-(cit22)\/*[position()=1]","volume-title":"Essentials of Carbohydrate Chemistry and Biochemistry","author":"Lindhorst","year":"2007","unstructured":"T. K.\n            Lindhorst\n          , Essentials of Carbohydrate Chemistry and Biochemistry, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, 3rd edn, 2007"},{"key":"C5NH00036J-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4118","DOI":"10.1128\/JVI.03476-12","volume":"87","author":"Chen","year":"2013","journal-title":"J. Virol."},{"key":"C5NH00036J-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1002\/pro.5560030202","volume":"3","author":"Merritt","year":"1994","journal-title":"Protein Sci."},{"key":"C5NH00036J-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1039\/b901828j","volume":"7","author":"Pieters","year":"2009","journal-title":"Org. Biomol. Chem."},{"key":"C5NH00036J-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1111\/j.1747-0285.2008.00758.x","volume":"73","author":"Bergstrom","year":"2009","journal-title":"Chem. Biol. Drug Des."},{"key":"C5NH00036J-(cit27)\/*[position()=1]","first-page":"153","volume":"133","author":"Sanchez","year":"2011","journal-title":"Indian J. Med. Res."},{"key":"C5NH00036J-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1039\/b201598f","volume":"127","author":"McAnally","year":"2002","journal-title":"Analyst"},{"key":"C5NH00036J-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1038\/nbt1100","volume":"23","author":"Sonnichsen","year":"2005","journal-title":"Nat. Biotechnol."},{"key":"C5NH00036J-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2262","DOI":"10.1039\/c2sc20031g","volume":"3","author":"Guerrini","year":"2012","journal-title":"Chem. Sci."},{"key":"C5NH00036J-(cit31)\/*[position()=1]","unstructured":"CDC, Centre for Disease Control and Prevention \u2013 Laboratory Testing for Cholera, 1993, pp. 62\u201388"},{"key":"C5NH00036J-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4620","DOI":"10.1128\/JCM.02019-10","volume":"48","author":"Evers","year":"2010","journal-title":"J. Clin. Microbiol."},{"key":"C5NH00036J-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1099\/jmm.0.47166-0","volume":"56","author":"Tuteja","year":"2007","journal-title":"J. Med. Microbiol."},{"key":"C5NH00036J-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4233","DOI":"10.1021\/ac300242k","volume":"84","author":"Schmit","year":"2012","journal-title":"Anal. Chem."}],"container-title":["Nanoscale Horizons"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2016\/NH\/C5NH00036J","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:23:01Z","timestamp":1782883381000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/nh\/article\/1\/1\/60-63\/482622"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.1039\/c5nh00036j","relation":{},"ISSN":["2055-6756","2055-6764"],"issn-type":[{"value":"2055-6756","type":"print"},{"value":"2055-6764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Supplementary Information","URL":"https:\/\/doi.org\/10.1039\/C5NH00036J","name":"related_data","group":{"name":"related_data","label":"RELATED DATA"}},{"value":"Jonathan Simpson (ResearcherID)","URL":"http:\/\/www.researcherid.com\/rid\/I-7305-2015","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"The Royal Society of Chemistry has an exclusive publication licence for this journal","name":"copyright_licence","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"This article is freely available. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (CC BY 3.0)","URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/","name":"copyright_licence","label":"OPEN ACCESS","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 29 July 2015; Accepted 20 November 2015;  Accepted Manuscript published 20 November 2015;  Advance Article published 9 December 2015;  Version of Record published 18 December 2015","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}