{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:33:05Z","timestamp":1791318785714,"version":"4.3.1"},"reference-count":78,"publisher":"Royal Society of Chemistry (RSC)","issue":"2","funder":[{"DOI":"10.13039\/100008730","name":"Kreftforeningen","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100008730","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Nanoscale"],"abstract":"<p>\n                    The zebrafish embryo enables characterization of nanoparticles against cancer in an\n                    <italic>in vivo<\/italic>\n                    vertebrate model.\n                  <\/p>","DOI":"10.1039\/c5nr07289a","type":"journal-article","created":{"date-parts":[[2015,12,9]],"date-time":"2015-12-09T11:37:14Z","timestamp":1449661034000},"page":"862-877","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":92,"title":["Zebrafish as a model system for characterization of nanoparticles against cancer"],"prefix":"10.1039","volume":"8","author":[{"given":"Lasse","family":"Evensen","sequence":"first","affiliation":[{"name":"Department of Biosciences"},{"name":"University of Oslo"},{"name":"0371 Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick L.","family":"Johansen","sequence":"additional","affiliation":[{"name":"Department of Biosciences"},{"name":"University of Oslo"},{"name":"0371 Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerbrand","family":"Koster","sequence":"additional","affiliation":[{"name":"Department of Biosciences"},{"name":"University of Oslo"},{"name":"0371 Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaizheng","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Chemistry"},{"name":"University of Oslo"},{"name":"Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Herfindal","sequence":"additional","affiliation":[{"name":"Department of Biomedicine"},{"name":"University of Bergen"},{"name":"5009 Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Speth","sequence":"additional","affiliation":[{"name":"Department of Biosciences"},{"name":"University of Oslo"},{"name":"0371 Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Fenaroli","sequence":"additional","affiliation":[{"name":"Department of Biosciences"},{"name":"University of Oslo"},{"name":"0371 Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon","family":"Hildahl","sequence":"additional","affiliation":[{"name":"Department of Biosciences"},{"name":"University of Oslo"},{"name":"0371 Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahla","family":"Bagherifam","sequence":"additional","affiliation":[{"name":"Department of Chemistry"},{"name":"University of Oslo"},{"name":"Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Tulotta","sequence":"additional","affiliation":[{"name":"Institute of Biology"},{"name":"Leiden University"},{"name":"2333 CC Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Prasmickaite","sequence":"additional","affiliation":[{"name":"Department of Tumour Biology"},{"name":"Oslo University Hospital Radiumhospital"},{"name":"Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunhild M.","family":"M\u00e6landsmo","sequence":"additional","affiliation":[{"name":"Department of Tumour Biology"},{"name":"Oslo University Hospital Radiumhospital"},{"name":"Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewa","family":"Snaar-Jagalska","sequence":"additional","affiliation":[{"name":"Institute of Biology"},{"name":"Leiden University"},{"name":"2333 CC Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gareth","family":"Griffiths","sequence":"additional","affiliation":[{"name":"Department of Biosciences"},{"name":"University of Oslo"},{"name":"0371 Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2016]]},"reference":[{"key":"C5NR07289A-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"87","DOI":"10.3322\/caac.21262","volume":"65","author":"Torre","year":"2015","journal-title":"CA-Cancer J. Clin."},{"key":"C5NR07289A-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1097\/01.gco.0000192996.20040.24","volume":"18","author":"Kayl","year":"2006","journal-title":"Curr. Opin. Obstet. Gynecol."},{"key":"C5NR07289A-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1038\/nrc3729","volume":"14","author":"Church","year":"2014","journal-title":"Nat. Rev. Cancer"},{"key":"C5NR07289A-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"12320","DOI":"10.1002\/anie.201403036","volume":"53","author":"Sun","year":"2014","journal-title":"Angew. Chem., Int. Ed."},{"key":"C5NR07289A-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1146\/annurev-med-040210-162544","volume":"63","author":"Wang","year":"2012","journal-title":"Annu. Rev. Med."},{"key":"C5NR07289A-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1093\/annonc\/mdh097","volume":"15","author":"O'Brien","year":"2004","journal-title":"Ann. Oncol."},{"key":"C5NR07289A-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1002\/path.4013","volume":"227","author":"He","year":"2012","journal-title":"J. Pathol."},{"key":"C5NR07289A-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1186\/1471-2407-13-453","volume":"13","author":"Teng","year":"2013","journal-title":"BMC Cancer"},{"key":"C5NR07289A-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S1535-6108(02)00052-1","volume":"1","author":"Amatruda","year":"2002","journal-title":"Cancer Cell"},{"key":"C5NR07289A-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1038\/nature12111","volume":"496","author":"Howe","year":"2013","journal-title":"Nature"},{"key":"C5NR07289A-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0145-305X(03)00103-4","volume":"28","author":"Lam","year":"2004","journal-title":"Dev. Comp. Immunol."},{"key":"C5NR07289A-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"e1002349","DOI":"10.1371\/journal.ppat.1002349","volume":"8","author":"Tobin","year":"2012","journal-title":"PLoS Pathog."},{"key":"C5NR07289A-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"e61801","DOI":"10.1371\/journal.pone.0061801","volume":"8","author":"Yang","year":"2013","journal-title":"PLoS One"},{"key":"C5NR07289A-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1111\/j.1749-6632.2012.06575.x","volume":"1266","author":"Konantz","year":"2012","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"C5NR07289A-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/nrd1606","volume":"4","author":"Zon","year":"2005","journal-title":"Nat. Rev. Drug Discovery"},{"key":"C5NR07289A-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.toxlet.2012.11.022","volume":"217","author":"Coradeghini","year":"2013","journal-title":"Toxicol. Lett."},{"key":"C5NR07289A-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1007\/s11095-012-0884-4","volume":"30","author":"Mohammad","year":"2013","journal-title":"Pharm. Res."},{"key":"C5NR07289A-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"657","DOI":"10.3109\/08958371003713745","volume":"22","author":"Palko","year":"2010","journal-title":"Inhalation Toxicol."},{"key":"C5NR07289A-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1002\/jps.2600841020","volume":"84","author":"Simon","year":"1995","journal-title":"J. Pharm. Sci."},{"key":"C5NR07289A-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0014-4827(85)90432-X","volume":"158","author":"Dan","year":"1985","journal-title":"Exp. Cell Res."},{"key":"C5NR07289A-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1096\/fj.04-2747rev","volume":"19","author":"Moghimi","year":"2005","journal-title":"FASEB J."},{"key":"C5NR07289A-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.ecoenv.2014.12.012","volume":"113","author":"Rocco","year":"2015","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"C5NR07289A-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1016\/j.chemosphere.2014.08.031","volume":"119","author":"Gao","year":"2015","journal-title":"Chemosphere"},{"key":"C5NR07289A-(cit24)\/*[position()=1]","first-page":"917","volume":"7","author":"Wang","year":"2014","journal-title":"Int. J. Ophthalmol."},{"key":"C5NR07289A-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7567","DOI":"10.1016\/j.biomaterials.2010.06.031","volume":"31","author":"Wagner","year":"2010","journal-title":"Biomaterials"},{"key":"C5NR07289A-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1016\/j.biomaterials.2012.10.068","volume":"34","author":"Gong","year":"2013","journal-title":"Biomaterials"},{"key":"C5NR07289A-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"12480","DOI":"10.1039\/c3nr04651f","volume":"5","author":"Wu","year":"2013","journal-title":"Nanoscale"},{"key":"C5NR07289A-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"11940","DOI":"10.1039\/C4NR02978J","volume":"6","author":"Wu","year":"2014","journal-title":"Nanoscale"},{"key":"C5NR07289A-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7014","DOI":"10.1021\/nn5019126","volume":"8","author":"Fenaroli","year":"2014","journal-title":"ACS Nano"},{"key":"C5NR07289A-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1007\/s00432-014-1767-3","volume":"141","author":"Bazak","year":"2015","journal-title":"J. Cancer Res. Clin. Oncol."},{"key":"C5NR07289A-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1126\/science.1229568","volume":"339","author":"Rodriguez","year":"2013","journal-title":"Science"},{"key":"C5NR07289A-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.ijpharm.2015.02.028","volume":"483","author":"Lollo","year":"2015","journal-title":"Int. J. Pharm."},{"key":"C5NR07289A-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.jconrel.2014.12.008","volume":"199","author":"Pasut","year":"2015","journal-title":"J. Controlled Release"},{"key":"C5NR07289A-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.ejpb.2014.04.002","volume":"88","author":"Myhren","year":"2014","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"C5NR07289A-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4183","DOI":"10.1039\/b901141b","volume":"19","author":"Xu","year":"2009","journal-title":"J. Mater. Chem."},{"key":"C5NR07289A-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/jbm.a.30056","volume":"70","author":"Meng","year":"2004","journal-title":"J. Biomed. Mater. Res., Part A"},{"key":"C5NR07289A-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/jbm.a.30068","volume":"70","author":"Meng","year":"2004","journal-title":"J. Biomed. Mater. Res., Part A"},{"key":"C5NR07289A-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1111\/j.1755-148X.2010.00690.x","volume":"23","author":"Prasmickaite","year":"2010","journal-title":"Pigm. Cell Melanoma Res."},{"key":"C5NR07289A-(cit39)\/*[position()=1]","volume-title":"Current protocols in microbiology","author":"Gao","year":"2005","unstructured":"L. Y. Gao and J.Manoranjan , Current protocols in microbiology , 2005 , ch. 10, Unit 10B 11"},{"key":"C5NR07289A-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2918","DOI":"10.1038\/nprot.2007.412","volume":"2","author":"Nicoli","year":"2007","journal-title":"Nat. Protoc."},{"key":"C5NR07289A-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"82","DOI":"10.18632\/oncoscience.11","volume":"1","author":"Nygaard","year":"2014","journal-title":"Oncoscience"},{"key":"C5NR07289A-(cit42)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1006\/dbio.2002.0711","volume":"248","author":"Lawson","year":"2002","journal-title":"Dev. Biol."},{"key":"C5NR07289A-(cit43)\/*[position()=1]","first-page":"5","author":"Jin","year":"2010","journal-title":"PLoS One"},{"key":"C5NR07289A-(cit44)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.gene.2015.05.065","volume":"569","author":"Stepanenko","year":"2015","journal-title":"Gene"},{"key":"C5NR07289A-(cit45)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"715","DOI":"10.2217\/nnm.11.19","volume":"6","author":"Jokerst","year":"2011","journal-title":"Nanomedicine"},{"key":"C5NR07289A-(cit46)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1038\/nrd1632","volume":"4","author":"Torchilin","year":"2005","journal-title":"Nat. Rev. Drug Discovery"},{"key":"C5NR07289A-(cit47)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"E943","DOI":"10.1073\/pnas.1321390111","volume":"111","author":"Bernut","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"C5NR07289A-(cit48)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev-bioeng-071811-150124","volume":"14","author":"Albanese","year":"2012","journal-title":"Annu. Rev. Biomed. Eng."},{"key":"C5NR07289A-(cit49)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1007\/s11095-007-9284-6","volume":"24","author":"van Vlerken","year":"2007","journal-title":"Pharm. Res."},{"key":"C5NR07289A-(cit50)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1002\/jps.20813","volume":"96","author":"Kommareddy","year":"2007","journal-title":"J. Pharm. Sci."},{"key":"C5NR07289A-(cit51)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1038\/nmat3780","volume":"13","author":"Weissleder","year":"2014","journal-title":"Nat. Mater."},{"key":"C5NR07289A-(cit52)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1021\/nn900330m","volume":"3","author":"Larsen","year":"2009","journal-title":"ACS Nano"},{"key":"C5NR07289A-(cit53)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1016\/S0006-3495(02)75493-3","volume":"82","author":"Li","year":"2002","journal-title":"Biophys. J."},{"key":"C5NR07289A-(cit54)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"e4343","DOI":"10.1371\/journal.pone.0004343","volume":"4","author":"Beduneau","year":"2009","journal-title":"PLoS One"},{"key":"C5NR07289A-(cit55)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1242\/jcs.115.4.849","volume":"115","author":"Beningo","year":"2002","journal-title":"J. Cell Sci."},{"key":"C5NR07289A-(cit56)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"e60989","DOI":"10.1371\/journal.pone.0060989","volume":"8","author":"Pacheco","year":"2013","journal-title":"PLoS One"},{"key":"C5NR07289A-(cit57)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.ijpharm.2005.10.010","volume":"307","author":"Owens 3rd","year":"2006","journal-title":"Int. J. Pharm."},{"issue":"Pt 10","key":"C5NR07289A-(cit58)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1242\/jcs.110.10.1199","volume":"110","author":"Diakonova","year":"1997","journal-title":"J. Cell Sci."},{"key":"C5NR07289A-(cit59)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/1465-9921-9-59","volume":"9","author":"Sulahian","year":"2008","journal-title":"Respir. Res."},{"key":"C5NR07289A-(cit60)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.jconrel.2010.03.016","volume":"145","author":"Li","year":"2010","journal-title":"J. Controlled Release"},{"key":"C5NR07289A-(cit61)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1007\/s00216-008-2066-0","volume":"391","author":"Mehne","year":"2008","journal-title":"Anal. Bioanal. Chem."},{"key":"C5NR07289A-(cit62)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1006\/dbio.2000.9995","volume":"230","author":"Isogai","year":"2001","journal-title":"Dev. Biol."},{"key":"C5NR07289A-(cit63)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"11079","DOI":"10.1039\/c3nr03954d","volume":"5","author":"Liao","year":"2013","journal-title":"Nanoscale"},{"key":"C5NR07289A-(cit64)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"e9536","DOI":"10.1371\/journal.pone.0009536","volume":"5","author":"Lee","year":"2010","journal-title":"PLoS One"},{"key":"C5NR07289A-(cit65)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5439","DOI":"10.1016\/j.biomaterials.2013.03.080","volume":"34","author":"Balasubramanian","year":"2013","journal-title":"Biomaterials"},{"key":"C5NR07289A-(cit66)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.ejps.2015.02.002","volume":"71","author":"Tamba","year":"2015","journal-title":"Eur. J. Pharm. Sci."},{"key":"C5NR07289A-(cit67)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9343","DOI":"10.1073\/pnas.0803728105","volume":"105","author":"Murphy","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"C5NR07289A-(cit68)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6115","DOI":"10.1073\/pnas.1220281110","volume":"110","author":"Pollinger","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"C5NR07289A-(cit69)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.biomaterials.2008.09.050","volume":"30","author":"Ehrenberg","year":"2009","journal-title":"Biomaterials"},{"key":"C5NR07289A-(cit70)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1021\/mp800051m","volume":"5","author":"Alexis","year":"2008","journal-title":"Mol. Pharm."},{"key":"C5NR07289A-(cit71)\/*[position()=1]","first-page":"1881","volume":"20","author":"Sheng","year":"2009","journal-title":"J. Mater. Sci.: Mater. Med."},{"key":"C5NR07289A-(cit72)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1080\/10717540500315930","volume":"13","author":"Wang","year":"2006","journal-title":"Drug Delivery"},{"key":"C5NR07289A-(cit73)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"705265","DOI":"10.1155\/2013\/705265","volume":"2013","author":"Perche","year":"2013","journal-title":"J. Drug Delivery"},{"key":"C5NR07289A-(cit74)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.2337\/db09-0663","volume":"59","author":"Lin","year":"2010","journal-title":"Diabetes"},{"key":"C5NR07289A-(cit75)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"20087","DOI":"10.1074\/jbc.M201766200","volume":"277","author":"Liang","year":"2002","journal-title":"J. Biol. Chem."},{"key":"C5NR07289A-(cit76)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.tcm.2005.11.008","volume":"16","author":"Wallez","year":"2006","journal-title":"Trends Cardiovasc. Med."},{"key":"C5NR07289A-(cit77)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.canlet.2013.10.036","volume":"344","author":"Bettum","year":"2014","journal-title":"Cancer Lett."},{"key":"C5NR07289A-(cit78)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0168-3659(99)00248-5","volume":"65","author":"Maeda","year":"2000","journal-title":"J. Controlled Release"}],"container-title":["Nanoscale"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2016\/NR\/C5NR07289A","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T05:24:10Z","timestamp":1782969850000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/nr\/article\/8\/2\/862-877\/486153"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":78,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.1039\/c5nr07289a","relation":{},"ISSN":["2040-3364","2040-3372"],"issn-type":[{"value":"2040-3364","type":"print"},{"value":"2040-3372","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]},"assertion":[{"value":"This document is CrossCheck deposited","name":"crosscheck","explanation":{"URL":"http:\/\/www.crossref.org\/crosscheck\/index.html"},"group":{"name":"crosscheck","label":"CROSSCHECK"}},{"value":"Supplementary Information","URL":"http:\/\/dx.doi.org\/10.1039\/C5NR07289A","name":"related_data","group":{"name":"related_data","label":"RELATED DATA"}},{"value":"The Royal Society of Chemistry has an exclusive publication licence for this journal","name":"copyright_licence","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"The accepted version of this article will be made freely available after a 12 month embargo period","name":"copyright_licence","label":"OPEN ACCESS","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"Received 20 October 2015; Accepted 28 November 2015; Advance Article published 9 December 2015; Version of Record published 23 December 2015","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}