{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:00:30Z","timestamp":1787004030241,"version":"build-2736575974"},"reference-count":44,"publisher":"Oxford University Press (OUP)","issue":"2","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["30830112"],"award-info":[{"award-number":["30830112"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81220108026"],"award-info":[{"award-number":["81220108026"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81430089"],"award-info":[{"award-number":["81430089"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Toxicol. Res."],"abstract":"<p>Glucocorticoid (GC) is a major factor for fetal tissue maturation and fate decision after birth.<\/p>","DOI":"10.1039\/c5tx00265f","type":"journal-article","created":{"date-parts":[[2016,1,15]],"date-time":"2016-01-15T12:55:43Z","timestamp":1452862543000},"page":"388-398","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Prenatal caffeine exposure-induced adrenal developmental abnormality in male offspring rats and its possible intrauterine programming mechanisms"],"prefix":"10.1093","volume":"5","author":[{"given":"Zheng","family":"He","sequence":"first","affiliation":[{"name":"Department of Pharmacology"},{"name":"Basic Medical School of Wuhan University"},{"name":"Wuhan 430071"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyan","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Pharmacology"},{"name":"Basic Medical School of Wuhan University"},{"name":"Wuhan 430071"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hegui","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Pharmacology"},{"name":"Basic Medical School of Wuhan University"},{"name":"Wuhan 430071"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lian","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pharmacology"},{"name":"Basic Medical School of Wuhan University"},{"name":"Wuhan 430071"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linlong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery"},{"name":"Zhongnan Hospital of Wuhan University"},{"name":"Wuhan 430071"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liaobin","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery"},{"name":"Zhongnan Hospital of Wuhan University"},{"name":"Wuhan 430071"},{"name":"China"},{"name":"Hubei Provincial Key Laboratory of Developmentally Originated Disorder"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Magdalou","sequence":"additional","affiliation":[{"name":"UMR 7365 CNRS-Universit\u00e9 de Lorraine"},{"name":"Facult\u00e9 de M\u00e9decine"},{"name":"Vand\u0153uvre-l\u00e8s-Nancy"},{"name":"France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pharmacology"},{"name":"Basic Medical School of Wuhan University"},{"name":"Wuhan 430071"},{"name":"China"},{"name":"Hubei Provincial Key Laboratory of Developmentally Originated Disorder"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2016]]},"reference":[{"key":"C5TX00265F-(cit1)\/*[position()=1]","first-page":"147","volume":"58","author":"Kuczkowski","year":"2003","journal-title":"Med. J. Malays."},{"key":"C5TX00265F-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1016\/j.fct.2004.05.002","volume":"42","author":"Knight","year":"2004","journal-title":"Food Chem. Toxicol."},{"key":"C5TX00265F-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"345","DOI":"10.3109\/10408447509079863","volume":"3","author":"Thayer","year":"1975","journal-title":"CRC Crit. Rev. Toxicol."},{"key":"C5TX00265F-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1093\/oxfordjournals.aje.a116763","volume":"137","author":"Fortier","year":"1993","journal-title":"Am. J. Epidemiol."},{"issue":"279","key":"C5TX00265F-(cit5)\/*[position()=1]","first-page":"e271","volume":"198","author":"Weng","year":"2008","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"4","key":"C5TX00265F-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1136\/eb-2013-101683","volume":"17","author":"Hollins Martin","year":"2013","journal-title":"Evid. Based Nurs."},{"key":"C5TX00265F-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1136\/bmj.38077.458438.EE","volume":"328","author":"James","year":"2004","journal-title":"BMJ"},{"key":"C5TX00265F-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.resp.2009.04.024","volume":"168","author":"Cayetanot","year":"2009","journal-title":"Respir. Physiol. Neurobiol."},{"key":"C5TX00265F-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"e44497","DOI":"10.1371\/journal.pone.0044497","volume":"7","author":"Xu","year":"2012","journal-title":"PLoS One"},{"key":"C5TX00265F-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.taap.2012.05.002","volume":"262","author":"Liu","year":"2012","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"C5TX00265F-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.taap.2012.08.016","volume":"264","author":"Xu","year":"2012","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"C5TX00265F-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.toxlet.2013.11.006","volume":"224","author":"Wang","year":"2014","journal-title":"Toxicol. Lett."},{"key":"C5TX00265F-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"750","DOI":"10.2174\/138920111795470868","volume":"12","author":"Marciniak","year":"2011","journal-title":"Curr. Pharm. Biotechnol."},{"key":"C5TX00265F-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1159\/000084092","volume":"8","author":"Ong","year":"2005","journal-title":"Endocr. Dev."},{"key":"C5TX00265F-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.yhbeh.2010.06.007","volume":"59","author":"Harris","year":"2011","journal-title":"Horm. Behav."},{"issue":"Suppl 3","key":"C5TX00265F-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"U49","DOI":"10.1530\/eje.0.151U049","volume":"151","author":"Seckl","year":"2004","journal-title":"Eur. J. Endocrinol."},{"key":"C5TX00265F-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.tox.2014.03.011","volume":"321","author":"Ping","year":"2014","journal-title":"Toxicology"},{"key":"C5TX00265F-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1152\/physrev.00020.2012","volume":"93","author":"Chapman","year":"2013","journal-title":"Physiol. Rev."},{"key":"C5TX00265F-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5568","DOI":"10.1210\/en.2003-0780","volume":"144","author":"Sun","year":"2003","journal-title":"Endocrinology"},{"key":"C5TX00265F-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1530\/rep.1.01198","volume":"133","author":"McNeil","year":"2007","journal-title":"Reproduction"},{"key":"C5TX00265F-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.ceb.2008.02.002","volume":"20","author":"Nerlov","year":"2008","journal-title":"Curr. Opin. Cell Biol."},{"key":"C5TX00265F-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1111\/j.1365-2265.2009.03683.x","volume":"73","author":"Inder","year":"2010","journal-title":"Clin. Endocrinol."},{"key":"C5TX00265F-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1203\/00006450-200208000-00003","volume":"52","author":"Robson","year":"2002","journal-title":"Pediatr. Res."},{"key":"C5TX00265F-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1096\/fj.07-9574LSF","volume":"22","author":"Reagan-Shaw","year":"2008","journal-title":"FASEB J."},{"key":"C5TX00265F-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1056\/NEJM197801262980403","volume":"298","author":"Robertson","year":"1978","journal-title":"N. Engl. J. Med."},{"key":"C5TX00265F-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.tox.2014.08.015","volume":"325C","author":"Zhang","year":"2014","journal-title":"Toxicology"},{"key":"C5TX00265F-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"34","DOI":"10.15690\/vramn.v68i6.671","author":"Kovtun","year":"2013","journal-title":"Vestn. Ross. Akad. Med. Nauk"},{"key":"C5TX00265F-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"43","DOI":"10.17772\/gp\/1689","volume":"85","author":"Seremak-Mrozikiewicz","year":"2014","journal-title":"Ginekol. Pol."},{"key":"C5TX00265F-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1203\/01.PDR.0000179392.59060.93","volume":"58","author":"Baquedano","year":"2005","journal-title":"Pediatr. Res."},{"key":"C5TX00265F-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/S0022-3476(63)80035-9","volume":"62","author":"Prader","year":"1963","journal-title":"J. Pediatr."},{"key":"C5TX00265F-(cit31)\/*[position()=1]","first-page":"241","volume":"6","author":"Nobili","year":"2008","journal-title":"Pediatr. Endocrinol. Rev."},{"key":"C5TX00265F-(cit32)\/*[position()=1]","first-page":"91","volume":"20","author":"Raha","year":"2007","journal-title":"Int. J. Mol. Med."},{"key":"C5TX00265F-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4754","DOI":"10.1210\/en.2007-0303","volume":"148","author":"Hyatt","year":"2007","journal-title":"Endocrinology"},{"key":"C5TX00265F-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/S0143-4004(03)00080-8","volume":"24","author":"Fowden","year":"2003","journal-title":"Placenta"},{"key":"C5TX00265F-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1210\/jc.2002-020979","volume":"88","author":"Guercio","year":"2003","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"C5TX00265F-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1530\/eje.0.1380524","volume":"138","author":"Cianfarani","year":"1998","journal-title":"Eur. J. Endocrinol."},{"key":"C5TX00265F-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.taap.2013.11.009","volume":"274","author":"Shen","year":"2014","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"1","key":"C5TX00265F-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1039\/C4TX00092G","volume":"4","author":"Xu","year":"2015","journal-title":"Toxicol. Res."},{"key":"C5TX00265F-(cit39)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1055\/s-0033-1345186","volume":"45","author":"Li","year":"2013","journal-title":"Horm. Metab. Res."},{"key":"C5TX00265F-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1002\/hep.23875","volume":"52","author":"Zeng","year":"2010","journal-title":"Hepatology"},{"key":"C5TX00265F-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1093\/carcin\/bgn273","volume":"30","author":"Staiger","year":"2009","journal-title":"Carcinogenesis"},{"key":"C5TX00265F-(cit42)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1203\/00006450-200110000-00009","volume":"50","author":"Engelbregt","year":"2001","journal-title":"Pediatr. Res."},{"key":"C5TX00265F-(cit43)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.toxlet.2012.09.007","volume":"214","author":"Tan","year":"2012","journal-title":"Toxicol. Lett."},{"key":"C5TX00265F-(cit44)\/*[position()=1]","volume-title":"Developmental and Reproductive Toxicology: A Practical Approach","author":"Vidmar","year":"2006","unstructured":"T. Vidmar , L.Freshwater and R.Collins, Understanding statistics in developmental and reproductive toxicology, in Developmental and Reproductive Toxicology: A Practical Approach, ed. R. D. Hood, Informa Healthcare, New York, 2006, pp. 542\u2013562"}],"container-title":["Toxicology Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2016\/TX\/C5TX00265F","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T16:44:18Z","timestamp":1718297058000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/toxres\/article\/5\/2\/388-398\/5568662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":44,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.1039\/c5tx00265f","relation":{},"ISSN":["2045-452X","2045-4538"],"issn-type":[{"value":"2045-452X","type":"print"},{"value":"2045-4538","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"The Royal Society of Chemistry has an exclusive publication licence for this journal","name":"copyright_licence","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"The accepted version of this article will be made freely available after a 12 month embargo period","name":"copyright_licence","label":"OPEN ACCESS","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 2 August 2015; Accepted 14 January 2016; Accepted Manuscript published 15 January 2016; Advance Article published 28 January 2016; Version of Record published 29 February 2016","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}