{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T05:09:24Z","timestamp":1789880964783,"version":"4.0.1"},"reference-count":52,"publisher":"Royal Society of Chemistry (RSC)","issue":"38","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["21172063"],"award-info":[{"award-number":["21172063"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["21472067"],"award-info":[{"award-number":["21472067"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["21502067"],"award-info":[{"award-number":["21502067"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Chem. Commun."],"abstract":"<p>\n                    Through rational design, the first TICT based fluorescent H\n                    <sub>2<\/sub>\n                    S probe was developed, which exhibited ideal properties such as fast response, good selectivity, high sensitivity, and it was suitable for visualization of exogenous and endogenous H\n                    <sub>2<\/sub>\n                    S in living cells.\n                  <\/p>","DOI":"10.1039\/c6cc00966b","type":"journal-article","created":{"date-parts":[[2016,3,30]],"date-time":"2016-03-30T07:36:39Z","timestamp":1459323399000},"page":"6415-6418","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":94,"title":["A TICT-based fluorescent probe for rapid and specific detection of hydrogen sulfide and its bio-imaging applications"],"prefix":"10.1039","volume":"52","author":[{"given":"Mingguang","family":"Ren","sequence":"first","affiliation":[{"name":"Institute of Fluorescent Probes for Biological Imaging"},{"name":"School of Chemistry and Chemical Engineering"},{"name":"School of Biological Science and Technology"},{"name":"University of Jinan"},{"name":"Jinan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beibei","family":"Deng","sequence":"additional","affiliation":[{"name":"Institute of Fluorescent Probes for Biological Imaging"},{"name":"School of Chemistry and Chemical Engineering"},{"name":"School of Biological Science and Technology"},{"name":"University of Jinan"},{"name":"Jinan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuqi","family":"Kong","sequence":"additional","affiliation":[{"name":"Institute of Fluorescent Probes for Biological Imaging"},{"name":"School of Chemistry and Chemical Engineering"},{"name":"School of Biological Science and Technology"},{"name":"University of Jinan"},{"name":"Jinan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Zhou","sequence":"additional","affiliation":[{"name":"Institute of Fluorescent Probes for Biological Imaging"},{"name":"School of Chemistry and Chemical Engineering"},{"name":"School of Biological Science and Technology"},{"name":"University of Jinan"},{"name":"Jinan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keyin","family":"Liu","sequence":"additional","affiliation":[{"name":"Institute of Fluorescent Probes for Biological Imaging"},{"name":"School of Chemistry and Chemical Engineering"},{"name":"School of Biological Science and Technology"},{"name":"University of Jinan"},{"name":"Jinan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaoping","family":"Xu","sequence":"additional","affiliation":[{"name":"Institute of Fluorescent Probes for Biological Imaging"},{"name":"School of Chemistry and Chemical Engineering"},{"name":"School of Biological Science and Technology"},{"name":"University of Jinan"},{"name":"Jinan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiying","family":"Lin","sequence":"additional","affiliation":[{"name":"Institute of Fluorescent Probes for Biological Imaging"},{"name":"School of Chemistry and Chemical Engineering"},{"name":"School of Biological Science and Technology"},{"name":"University of Jinan"},{"name":"Jinan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2016]]},"reference":[{"key":"C6CC00966B-(cit1a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1038\/nrd2425","volume":"6","author":"Szabo","year":"2007","journal-title":"Nat. Rev. Drug Discovery"},{"key":"C6CC00966B-(cit1b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1146\/annurev-pharmtox-010510-100505","volume":"51","author":"Li","year":"2011","journal-title":"Annu. Rev. Pharmacol."},{"key":"C6CC00966B-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"22457","DOI":"10.1074\/jbc.M109.010868","volume":"284","author":"Singh","year":"2009","journal-title":"J. Biol. Chem."},{"key":"C6CC00966B-(cit3)\/*[position()=1]","first-page":"348","volume":"62","author":"Dominy","year":"2004","journal-title":"Nutr. Rev."},{"key":"C6CC00966B-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"21903","DOI":"10.1074\/jbc.R110.128363","volume":"285","author":"Kabil","year":"2010","journal-title":"J. Biol. Chem."},{"key":"C6CC00966B-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1089\/ars.2008.2253","volume":"11","author":"Shibuya","year":"2008","journal-title":"Antioxid. Redox Signaling"},{"key":"C6CC00966B-(cit6a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1096\/fj.04-3583fje","volume":"19","author":"Li","year":"2005","journal-title":"FASEB J."},{"key":"C6CC00966B-(cit6b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1096\/fj.05-4712fje","volume":"20","author":"Yang","year":"2006","journal-title":"FASEB J."},{"key":"C6CC00966B-(cit6c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1523\/JNEUROSCI.16-03-01066.1996","volume":"16","author":"Abe","year":"1996","journal-title":"J. Neurosci."},{"key":"C6CC00966B-(cit6d)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1126\/science.1162667","volume":"322","author":"Yang","year":"2008","journal-title":"Science"},{"key":"C6CC00966B-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1016\/S0006-291X(02)00422-9","volume":"293","author":"Eto","year":"2002","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"C6CC00966B-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1002\/ajmg.a.10847","volume":"116A","author":"Kamoun","year":"2003","journal-title":"Am. J. Med. Genet., Part A"},{"key":"C6CC00966B-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1113\/jphysiol.2005.097642","volume":"569","author":"Yang","year":"2005","journal-title":"J. Physiol."},{"key":"C6CC00966B-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/hep.20817","volume":"42","author":"Fiorucci","year":"2005","journal-title":"Hepatology"},{"key":"C6CC00966B-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1016\/j.dyepig.2013.06.018","volume":"99","author":"Bae","year":"2013","journal-title":"Dyes Pigm."},{"key":"C6CC00966B-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1002\/1521-4109(200012)12:18<1453::AID-ELAN1453>3.0.CO;2-Z","volume":"12","author":"Lawrence","year":"2000","journal-title":"Electroanalysis"},{"key":"C6CC00966B-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.ab.2005.03.024","volume":"341","author":"Doeller","year":"2005","journal-title":"Anal. Biochem."},{"key":"C6CC00966B-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1089\/ars.2008.2132","volume":"11","author":"Ishigami","year":"2008","journal-title":"Antioxid. Redox Signaling"},{"key":"C6CC00966B-(cit15a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"12234","DOI":"10.1039\/C4CC03312D","volume":"50","author":"Yu","year":"2014","journal-title":"Chem. Commun."},{"key":"C6CC00966B-(cit15b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.jinorgbio.2013.10.010","volume":"133","author":"Lippert","year":"2014","journal-title":"J. Inorg. Biochem."},{"key":"C6CC00966B-(cit15c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4596","DOI":"10.1039\/C4CS00298A","volume":"44","author":"Lin","year":"2015","journal-title":"Chem. Soc. Rev."},{"key":"C6CC00966B-(cit15d)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1039\/C4CC08522A","volume":"51","author":"He","year":"2015","journal-title":"Chem. Commun."},{"key":"C6CC00966B-(cit15e)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"10871","DOI":"10.1039\/c2cc36141h","volume":"48","author":"Xu","year":"2012","journal-title":"Chem. Commun."},{"key":"C6CC00966B-(cit15f)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.talanta.2014.01.001","volume":"121","author":"Jiang","year":"2014","journal-title":"Talanta"},{"key":"C6CC00966B-(cit15g)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.aca.2015.03.017","volume":"879","author":"Gu","year":"2015","journal-title":"Anal. Chim. Acta"},{"key":"C6CC00966B-(cit15h)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.1039\/C4AN02285H","volume":"140","author":"Xu","year":"2015","journal-title":"Analyst"},{"key":"C6CC00966B-(cit15i)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8342","DOI":"10.1039\/c2ob26235e","volume":"10","author":"Wu","year":"2012","journal-title":"Org. Biomol. Chem."},{"key":"C6CC00966B-(cit15j)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1039\/C2CC37725J","volume":"49","author":"Wan","year":"2013","journal-title":"Chem. Commun."},{"key":"C6CC00966B-(cit15k)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8656","DOI":"10.1039\/c3cc44539a","volume":"49","author":"Li","year":"2013","journal-title":"Chem. Commun."},{"key":"C6CC00966B-(cit15l)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9481","DOI":"10.1021\/jo5014838","volume":"79","author":"Liu","year":"2014","journal-title":"J. Org. Chem."},{"key":"C6CC00966B-(cit15m)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1039\/C4AN01909A","volume":"140","author":"Guo","year":"2015","journal-title":"Analyst"},{"key":"C6CC00966B-(cit15n)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1039\/C4CC08522A","volume":"51","author":"He","year":"2015","journal-title":"Chem. Commun."},{"key":"C6CC00966B-(cit15o)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"17797","DOI":"10.1039\/C4RA16578K","volume":"5","author":"Huang","year":"2015","journal-title":"RSC Adv."},{"key":"C6CC00966B-(cit15p)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3131","DOI":"10.1039\/C5CC09267A","volume":"52","author":"Feng","year":"2016","journal-title":"Chem. Commun."},{"key":"C6CC00966B-(cit15q)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5295","DOI":"10.1016\/j.bmcl.2013.07.072","volume":"23","author":"Chen","year":"2013","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"C6CC00966B-(cit15r)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.dyepig.2014.03.039","volume":"110","author":"Liu","year":"2014","journal-title":"Dyes Pigm."},{"key":"C6CC00966B-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3899","DOI":"10.1021\/cr940745l","volume":"103","author":"Grabowski","year":"2003","journal-title":"Chem. Rev."},{"key":"C6CC00966B-(cit17a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"15811","DOI":"10.1039\/C4CC08010F","volume":"50","author":"Cao","year":"2014","journal-title":"Chem. Commun."},{"key":"C6CC00966B-(cit17b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.snb.2014.03.087","volume":"199","author":"Chen","year":"2014","journal-title":"Sens. Actuators, B"},{"key":"C6CC00966B-(cit17c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.snb.2014.04.070","volume":"200","author":"Liu","year":"2014","journal-title":"Sens. Actuators, B"},{"key":"C6CC00966B-(cit17d)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"12641","DOI":"10.1039\/C5CC03857J","volume":"51","author":"Luedtke","year":"2015","journal-title":"Chem. Commun."},{"key":"C6CC00966B-(cit17e)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1039\/C5CC08217J","volume":"52","author":"Reja","year":"2016","journal-title":"Chem. Commun."},{"key":"C6CC00966B-(cit17f)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1039\/C4CC08258C","volume":"51","author":"Zhu","year":"2015","journal-title":"Chem. Commun."},{"key":"C6CC00966B-(cit18a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1021\/ja209292b","volume":"134","author":"Yuan","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"C6CC00966B-(cit18b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"13510","DOI":"10.1021\/ja305802v","volume":"134","author":"Yuan","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"C6CC00966B-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1002\/anie.201207701","volume":"52","author":"Chen","year":"2013","journal-title":"Angew. Chem., Int. Ed."},{"key":"C6CC00966B-(cit20a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3260","DOI":"10.1021\/ol501272z","volume":"16","author":"I\u015f\u0131k","year":"2014","journal-title":"Org. Lett."},{"key":"C6CC00966B-(cit20b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6925","DOI":"10.1039\/C5CC01130B","volume":"51","author":"Kong","year":"2015","journal-title":"Chem. Commun."},{"key":"C6CC00966B-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.tips.2007.09.003","volume":"28","author":"Wallace","year":"2007","journal-title":"Trends Pharmacol. Sci."},{"key":"C6CC00966B-(cit22a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2760","DOI":"10.1039\/C5CC09092J","volume":"52","author":"Li","year":"2016","journal-title":"Chem. Commun."},{"key":"C6CC00966B-(cit22b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.bios.2015.10.049","volume":"77","author":"Xu","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"C6CC00966B-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/ncomms1506","volume":"2","author":"Qian","year":"2011","journal-title":"Nat. Commun."}],"container-title":["Chemical Communications"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2016\/CC\/C6CC00966B","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T17:50:15Z","timestamp":1782928215000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/cc\/article\/52\/38\/6415-6418\/512573"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":52,"journal-issue":{"issue":"38","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.1039\/c6cc00966b","relation":{},"ISSN":["1359-7345","1364-548X"],"issn-type":[{"value":"1359-7345","type":"print"},{"value":"1364-548X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Supplementary Information","URL":"https:\/\/doi.org\/10.1039\/C6CC00966B","name":"related_data","group":{"name":"related_data","label":"RELATED DATA"}},{"value":"The Royal Society of Chemistry has an exclusive publication licence for this journal","name":"copyright_licence","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 31 January 2016; Accepted 30 March 2016; Accepted Manuscript published 30 March 2016; Advance Article published 19 April 2016; Version of Record published 3 May 2016","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}