{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T07:01:47Z","timestamp":1782975707144,"version":"3.54.5"},"reference-count":23,"publisher":"Royal Society of Chemistry (RSC)","issue":"70","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["21271066"],"award-info":[{"award-number":["21271066"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["21571053"],"award-info":[{"award-number":["21571053"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["U1204516"],"award-info":[{"award-number":["U1204516"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Chem. Commun."],"abstract":"<p>Hollow silica nanospheres coated with pH-sensitive insoluble calcium salts are prepared for pH-responsive sustained release of anticancer drugs.<\/p>","DOI":"10.1039\/c6cc04538c","type":"journal-article","created":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T12:30:46Z","timestamp":1470054646000},"page":"10652-10655","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Hollow silica nanospheres coated with insoluble calcium salts for pH-responsive sustained release of anticancer drugs"],"prefix":"10.1039","volume":"52","author":[{"given":"Yuming","family":"Guo","sequence":"first","affiliation":[{"name":"Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals"},{"name":"Key Laboratory of Green Chemical Media and Reactions"},{"name":"Ministry of Education"},{"name":"Henan Normal University"},{"name":"Xinxiang"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qilong","family":"Fang","sequence":"additional","affiliation":[{"name":"Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals"},{"name":"Key Laboratory of Green Chemical Media and Reactions"},{"name":"Ministry of Education"},{"name":"Henan Normal University"},{"name":"Xinxiang"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Li","sequence":"additional","affiliation":[{"name":"Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals"},{"name":"Key Laboratory of Green Chemical Media and Reactions"},{"name":"Ministry of Education"},{"name":"Henan Normal University"},{"name":"Xinxiang"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weike","family":"Shi","sequence":"additional","affiliation":[{"name":"Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals"},{"name":"Key Laboratory of Green Chemical Media and Reactions"},{"name":"Ministry of Education"},{"name":"Henan Normal University"},{"name":"Xinxiang"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Zhang","sequence":"additional","affiliation":[{"name":"Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals"},{"name":"Key Laboratory of Green Chemical Media and Reactions"},{"name":"Ministry of Education"},{"name":"Henan Normal University"},{"name":"Xinxiang"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Feng","sequence":"additional","affiliation":[{"name":"Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals"},{"name":"Key Laboratory of Green Chemical Media and Reactions"},{"name":"Ministry of Education"},{"name":"Henan Normal University"},{"name":"Xinxiang"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weili","family":"Jia","sequence":"additional","affiliation":[{"name":"Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals"},{"name":"Key Laboratory of Green Chemical Media and Reactions"},{"name":"Ministry of Education"},{"name":"Henan Normal University"},{"name":"Xinxiang"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Yang","sequence":"additional","affiliation":[{"name":"Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals"},{"name":"Key Laboratory of Green Chemical Media and Reactions"},{"name":"Ministry of Education"},{"name":"Henan Normal University"},{"name":"Xinxiang"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2016]]},"reference":[{"key":"C6CC04538C-(cit1)\/*[position()=1]","first-page":"1291","volume":"10","author":"Cabeza","year":"2015","journal-title":"Int. J. Nanomed."},{"key":"C6CC04538C-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1002\/adma.201303123","volume":"26","author":"He","year":"2014","journal-title":"Adv. Mater."},{"key":"C6CC04538C-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8344","DOI":"10.1021\/nn405092w","volume":"7","author":"Duan","year":"2013","journal-title":"ACS Nano"},{"key":"C6CC04538C-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7548","DOI":"10.1002\/anie.200604488","volume":"46","author":"Vallet-Reg\u00ed","year":"2007","journal-title":"Angew. Chem., Int. Ed."},{"key":"C6CC04538C-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7281","DOI":"10.1002\/anie.201001847","volume":"49","author":"Climent","year":"2010","journal-title":"Angew. Chem., Int. Ed."},{"key":"C6CC04538C-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1002\/adma.201104763","volume":"24","author":"Tang","year":"2012","journal-title":"Adv. Mater."},{"key":"C6CC04538C-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4451","DOI":"10.1021\/ja028650l","volume":"125","author":"Lai","year":"2003","journal-title":"J. Am. Chem. Soc."},{"key":"C6CC04538C-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1021\/ar600032u","volume":"40","author":"Trewyn","year":"2007","journal-title":"Acc. Chem. Res."},{"key":"C6CC04538C-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S1357-4310(99)01615-9","volume":"6","author":"Stubbs","year":"2000","journal-title":"Mol. Med. Today"},{"key":"C6CC04538C-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"15136","DOI":"10.1021\/ja904982j","volume":"131","author":"Du","year":"2009","journal-title":"J. Am. Chem. Soc."},{"key":"C6CC04538C-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9788","DOI":"10.1021\/nn2033105","volume":"5","author":"Gao","year":"2011","journal-title":"ACS Nano"},{"key":"C6CC04538C-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1021\/cm3037197","volume":"25","author":"Chang","year":"2013","journal-title":"Chem. Mater."},{"key":"C6CC04538C-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.biomaterials.2010.08.114","volume":"32","author":"Huang","year":"2011","journal-title":"Biomaterials"},{"key":"C6CC04538C-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9819","DOI":"10.1021\/la501833u","volume":"30","author":"Yang","year":"2014","journal-title":"Langmuir"},{"key":"C6CC04538C-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8050","DOI":"10.1039\/c0jm00852d","volume":"20","author":"Cheang","year":"2010","journal-title":"J. Mater. Chem."},{"key":"C6CC04538C-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.msec.2015.02.019","volume":"50","author":"He","year":"2015","journal-title":"Mater. Sci. Eng., C"},{"key":"C6CC04538C-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2447","DOI":"10.1039\/c3tb20365d","volume":"1","author":"Yang","year":"2013","journal-title":"J. Mater. Chem. B"},{"key":"C6CC04538C-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"10636","DOI":"10.1039\/c2cc35103j","volume":"48","author":"Guo","year":"2012","journal-title":"Chem. Commun."},{"key":"C6CC04538C-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3764","DOI":"10.1021\/la5000765","volume":"30","author":"Wang","year":"2014","journal-title":"Langmuir"},{"key":"C6CC04538C-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4281","DOI":"10.1021\/bm501290t","volume":"15","author":"Deng","year":"2014","journal-title":"Biomacromolecules"},{"key":"C6CC04538C-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.ijpharm.2003.09.008","volume":"269","author":"Jimenez-Kairuz","year":"2004","journal-title":"Int. J. Pharm."},{"key":"C6CC04538C-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"17560","DOI":"10.1021\/ja207150n","volume":"133","author":"Du","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"C6CC04538C-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5326","DOI":"10.1021\/ja068894w","volume":"129","author":"Kang","year":"2007","journal-title":"J. Am. Chem. Soc."}],"container-title":["Chemical Communications"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2016\/CC\/C6CC04538C","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T05:29:39Z","timestamp":1782970179000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/cc\/article\/52\/70\/10652-10655\/513465"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":23,"journal-issue":{"issue":"70","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.1039\/c6cc04538c","relation":{},"ISSN":["1359-7345","1364-548X"],"issn-type":[{"value":"1359-7345","type":"print"},{"value":"1364-548X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Supplementary Information","URL":"https:\/\/doi.org\/10.1039\/C6CC04538C","name":"related_data","group":{"name":"related_data","label":"RELATED DATA"}},{"value":"The Royal Society of Chemistry has an exclusive publication licence for this journal","name":"copyright_licence","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 31 May 2016; Accepted 1 August 2016;  Accepted Manuscript published 1 August 2016;  Advance Article published 9 August 2016;  Version of Record published 23 August 2016","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}