{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T19:44:14Z","timestamp":1782935054725,"version":"3.54.5"},"reference-count":60,"publisher":"Royal Society of Chemistry (RSC)","issue":"5","content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<p>\n                    The compounds of\n                    <italic>Rubus<\/italic>\n                    spp. Blackberry (RSB) were isolated and identified by a bioassay-guided method, and their antithrombotic effects and mechanism were investigated with the acute blood stasis rat model.\n                  <\/p>","DOI":"10.1039\/c6fo01717g","type":"journal-article","created":{"date-parts":[[2017,2,9]],"date-time":"2017-02-09T06:23:43Z","timestamp":1486621423000},"page":"2000-2012","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Antithrombotic effect and mechanism of Rubus spp. Blackberry"],"prefix":"10.1039","volume":"8","author":[{"given":"Pingyao","family":"Xie","sequence":"first","affiliation":[{"name":"Institute of Chinese Materia Medica"},{"name":"Henan University"},{"name":"Kaifeng 475004"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Institute of Chinese Materia Medica"},{"name":"Henan University"},{"name":"Kaifeng 475004"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuebiao","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Chinese Materia Medica"},{"name":"Henan University"},{"name":"Kaifeng 475004"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinfeng","family":"Wei","sequence":"additional","affiliation":[{"name":"Institute of Chinese Materia Medica"},{"name":"Henan University"},{"name":"Kaifeng 475004"},{"name":"China"},{"name":"Kaifeng Key Laboratory of functional components in health food"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1822-6249","authenticated-orcid":false,"given":"Wenyi","family":"Kang","sequence":"additional","affiliation":[{"name":"Institute of Chinese Materia Medica"},{"name":"Henan University"},{"name":"Kaifeng 475004"},{"name":"China"},{"name":"Kaifeng Key Laboratory of functional components in health food"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2017]]},"reference":[{"key":"C6FO01717G-(cit1)\/*[position()=1]","first-page":"10","volume-title":"Flora Reipublicae Popularis Sinicae","volume":"37","author":"Yu","year":"1985","unstructured":"D. J. Yu , in Flora Reipublicae Popularis Sinicae, Science Press, Beijing, 1985, vol. 37, p. 10"},{"key":"C6FO01717G-(cit2)\/*[position()=1]","first-page":"105","volume":"21","author":"Li","year":"2012","journal-title":"J. Plant Resour. Environ."},{"key":"C6FO01717G-(cit3)\/*[position()=1]","first-page":"68","volume":"11","author":"Liu","year":"1994","journal-title":"J. Shenyang Pharm. Univ."},{"key":"C6FO01717G-(cit4)\/*[position()=1]","first-page":"767","volume":"23","author":"Meng","year":"2011","journal-title":"Nat. Prod. Res. Dev."},{"key":"C6FO01717G-(cit5)\/*[position()=1]","first-page":"68","volume":"11","author":"Liu","year":"1994","journal-title":"J. Shenyang Pharm. Univ."},{"key":"C6FO01717G-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9542","DOI":"10.1021\/jf102590p","volume":"58","author":"Cuevas-Rodr\u00edguez","year":"2010","journal-title":"J. Agric. Food Chem."},{"key":"C6FO01717G-(cit7)\/*[position()=1]","first-page":"984","volume":"26","author":"Pr","year":"2011","journal-title":"Nutr. Hosp."},{"key":"C6FO01717G-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1089\/jmf.2006.238","volume":"10","author":"Jin","year":"2007","journal-title":"J. Med. Food"},{"key":"C6FO01717G-(cit9)\/*[position()=1]","first-page":"351","volume":"35","author":"Zhang","year":"2014","journal-title":"Sci. Technol. Food Ind."},{"key":"C6FO01717G-(cit10)\/*[position()=1]","first-page":"35","volume":"32","author":"Gu","year":"2013","journal-title":"J. Henan Univ., Med. Sci."},{"key":"C6FO01717G-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1111\/j.1476-5381.1994.tb17126.x","volume":"113","author":"Berry","year":"1994","journal-title":"Br. J. Pharmacol."},{"key":"C6FO01717G-(cit12)\/*[position()=1]","first-page":"2253","volume":"17","author":"Bao","year":"2009","journal-title":"Chin. J. Gerontol."},{"key":"C6FO01717G-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1055\/s-0037-1614648","volume":"82","author":"Rosendaal","year":"1999","journal-title":"Thromb. Haemostasis"},{"key":"C6FO01717G-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1248\/cpb.41.1238","volume":"41","author":"Basnet","year":"1993","journal-title":"Chem. Pharm. Bull."},{"key":"C6FO01717G-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1016\/j.fitote.2012.04.011","volume":"83","author":"Katerere","year":"2012","journal-title":"Fitoterapia"},{"key":"C6FO01717G-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3724\/SP.J.1009.2010.00012","volume":"8","author":"Liu","year":"2010","journal-title":"Chin. J. Nat. Med."},{"key":"C6FO01717G-(cit17)\/*[position()=1]","first-page":"104","volume":"40","author":"Ren","year":"2009","journal-title":"Chin. Tradit. Herb. Drugs"},{"key":"C6FO01717G-(cit18)\/*[position()=1]","first-page":"851","volume":"30","author":"Liu","year":"2013","journal-title":"J. Shenyang Pharm. Univ."},{"key":"C6FO01717G-(cit19)\/*[position()=1]","first-page":"2931","volume":"22","author":"Zhang","year":"2011","journal-title":"China Pharm."},{"key":"C6FO01717G-(cit20)\/*[position()=1]","first-page":"1905","volume":"43","author":"Guo","year":"2012","journal-title":"Chin. Tradit. Herb. Drugs"},{"key":"C6FO01717G-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1007\/s12257-013-0173-z","volume":"18","author":"Dong","year":"2013","journal-title":"Biotechnol. Bioprocess Eng."},{"key":"C6FO01717G-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1080\/14786419.2014.950576","volume":"28","author":"Liu","year":"2014","journal-title":"Nat. Prod. Res."},{"key":"C6FO01717G-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4277","DOI":"10.1016\/j.bmcl.2004.05.086","volume":"14","author":"Xu","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"C6FO01717G-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1080\/10575630290020055","volume":"16","author":"Ouyang","year":"2002","journal-title":"Nat. Prod. Lett."},{"key":"C6FO01717G-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1021\/jf062421r","volume":"55","author":"Wu","year":"2007","journal-title":"J. Agric. Food Chem."},{"key":"C6FO01717G-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/S0031-9422(96)00644-9","volume":"44","author":"Chung","year":"1997","journal-title":"Phytochemistry"},{"key":"C6FO01717G-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1056\/NEJM196810172791603","volume":"279","author":"Corrigan Jr.","year":"1968","journal-title":"N. Engl. J. Med."},{"key":"C6FO01717G-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.fct.2006.10.005","volume":"45","author":"Chan","year":"2007","journal-title":"Food Chem. Toxicol."},{"key":"C6FO01717G-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s00580-005-0567-1","volume":"14","author":"Tibbs","year":"2005","journal-title":"Comp. Clin. Pathol."},{"key":"C6FO01717G-(cit30)\/*[position()=1]","volume-title":"Basis of Clinical Examination","author":"Xiong","year":"2003","unstructured":"L. F. Xiong and S. R.Li, Basis of Clinical Examination, People's Medical Publishing House, Beijing, 2003, pp. 88\u201393"},{"key":"C6FO01717G-(cit31)\/*[position()=1]","first-page":"18","volume":"6","author":"Xie","year":"1996","journal-title":"China J. Tradit. Chin. Med. Pharm."},{"key":"C6FO01717G-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1016\/S0895-7061(97)00095-2","volume":"10","author":"Gomi","year":"1997","journal-title":"Am. J. Hypertens."},{"key":"C6FO01717G-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0021-9150(90)90130-B","volume":"83","author":"Koppensteiner","year":"1990","journal-title":"Atherosclerosis"},{"key":"C6FO01717G-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.foodchem.2006.08.022","volume":"103","author":"Hsieh","year":"2007","journal-title":"Food Chem."},{"key":"C6FO01717G-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/0022-510X(91)90040-E","volume":"101","author":"Elwan","year":"1991","journal-title":"J. Neurol. Sci."},{"key":"C6FO01717G-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1016\/0002-8703(82)90169-7","volume":"104","author":"Dormandy","year":"1982","journal-title":"Am. Heart J."},{"key":"C6FO01717G-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/0049-3848(95)00126-C","volume":"79","author":"G\u00f6r\u00f6g","year":"1995","journal-title":"Thromb. Res."},{"key":"C6FO01717G-(cit38)\/*[position()=1]","first-page":"304","volume":"15","author":"Wang","year":"2006","journal-title":"Chin. J. Hemorheol."},{"key":"C6FO01717G-(cit39)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.jep.2007.11.031","volume":"116","author":"Lu","year":"2008","journal-title":"J. Ethnopharmacol."},{"key":"C6FO01717G-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1161\/01.CIR.96.4.1102","volume":"96","author":"Folsom","year":"1997","journal-title":"Circulation"},{"key":"C6FO01717G-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1016\/S1357-2725(02)00087-0","volume":"34","author":"Klinken","year":"2002","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"C6FO01717G-(cit42)\/*[position()=1]","first-page":"19","volume":"7","author":"Zhao","year":"1997","journal-title":"Chin. J. Hemorheol."},{"key":"C6FO01717G-(cit43)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1136\/bmj.296.6618.313","volume":"296","author":"Peto","year":"1988","journal-title":"Br. Med. J."},{"key":"C6FO01717G-(cit44)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.jep.2015.06.030","volume":"173","author":"Dang","year":"2015","journal-title":"J. Ethnopharmacol."},{"key":"C6FO01717G-(cit45)\/*[position()=1]","first-page":"34","volume":"14","author":"Schr\u00f6r","year":"1993","journal-title":"Eur. Heart J."},{"key":"C6FO01717G-(cit46)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1111\/j.1526-4610.1991.hed3103156.x","volume":"31","author":"Puig-Parellada","year":"1991","journal-title":"Headache"},{"key":"C6FO01717G-(cit47)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/0090-6980(88)90024-X","volume":"35","author":"Homo-Delarche","year":"1988","journal-title":"Prostaglandins"},{"key":"C6FO01717G-(cit48)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1620\/tjem.165.79","volume":"165","author":"Furuhashi","year":"1991","journal-title":"Tohoku J. Exp. Med."},{"key":"C6FO01717G-(cit49)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1016\/0140-6736(92)93147-F","volume":"340","author":"Celermajer","year":"1992","journal-title":"Lancet"},{"key":"C6FO01717G-(cit50)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1161\/01.RES.87.10.840","volume":"87","author":"Cai","year":"2000","journal-title":"Circ. Res."},{"key":"C6FO01717G-(cit51)\/*[position()=1]","first-page":"356","volume":"S1","author":"Cao","year":"2004","journal-title":"J. Chin. Physician"},{"key":"C6FO01717G-(cit52)\/*[position()=1]","first-page":"29","volume":"21","author":"Xue","year":"2006","journal-title":"J. Henan Univ. Chin. Med."},{"key":"C6FO01717G-(cit53)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1016\/S0140-6736(94)92827-4","volume":"344","author":"Haynes","year":"1994","journal-title":"Lancet"},{"key":"C6FO01717G-(cit54)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1161\/01.RES.0000088351.58510.21","volume":"93","author":"Massion","year":"2003","journal-title":"Circ. Res."},{"key":"C6FO01717G-(cit55)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1038\/377239a0","volume":"377","author":"Huang","year":"1995","journal-title":"Nature"},{"key":"C6FO01717G-(cit56)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1161\/CIRCULATIONAHA.105.602532","volume":"113","author":"F\u00f6rstermann","year":"2006","journal-title":"Circulation"},{"key":"C6FO01717G-(cit58)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1177\/1470320310397405","volume":"12","author":"Gromotowicz","year":"2011","journal-title":"J. Renin-Angiotensin-Aldosterone Syst."},{"key":"C6FO01717G-(cit59)\/*[position()=1]","first-page":"22","volume":"2014","author":"Chen","year":"2014","journal-title":"BioMed Res. Int."},{"key":"C6FO01717G-(cit60)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1055\/s-0038-1651861","volume":"38","author":"Marsh","year":"1977","journal-title":"Thromb. Haemostasis"},{"key":"C6FO01717G-(cit61)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1016\/j.fct.2009.04.026","volume":"47","author":"Li","year":"2009","journal-title":"Food Chem. Toxicol."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2017\/FO\/C6FO01717G","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T17:54:31Z","timestamp":1782928471000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/8\/5\/2000-2012\/524569"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":60,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.1039\/c6fo01717g","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Wenyi Kang (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-1822-6249","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"The Royal Society of Chemistry has an exclusive publication licence for this journal","name":"copyright_licence","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 24 November 2016; Accepted 1 February 2017; Accepted Manuscript published 9 February 2017; Advance Article published 9 May 2017; Version of Record published 24 May 2017","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}