{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T09:02:15Z","timestamp":1791277335132,"version":"4.1.0"},"reference-count":54,"publisher":"Royal Society of Chemistry (RSC)","issue":"23","content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Lab Chip"],"abstract":"<p>Inkjet printing is combined with roll-coating to fabricate digital microfluidic (DMF) devices outside of the cleanroom for inexpensive, miniaturized diagnostic assays, with straightforward scalability towards mass production.<\/p>","DOI":"10.1039\/c6lc01064d","type":"journal-article","created":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T07:53:52Z","timestamp":1477986832000},"page":"4560-4568","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":104,"title":["An inkjet printed, roll-coated digital microfluidic device for inexpensive, miniaturized diagnostic assays"],"prefix":"10.1039","volume":"16","author":[{"given":"Christopher","family":"Dixon","sequence":"first","affiliation":[{"name":"Department of Chemistry"},{"name":"University of Toronto"},{"name":"Toronto"},{"name":"Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alphonsus H. C.","family":"Ng","sequence":"additional","affiliation":[{"name":"Donnelly Centre for Cellular and Biomolecular Research"},{"name":"University of Toronto"},{"name":"Toronto"},{"name":"Canada"},{"name":"Institute for Biomaterials and Biomedical Engineering"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan","family":"Fobel","sequence":"additional","affiliation":[{"name":"Donnelly Centre for Cellular and Biomolecular Research"},{"name":"University of Toronto"},{"name":"Toronto"},{"name":"Canada"},{"name":"Institute for Biomaterials and Biomedical Engineering"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark B.","family":"Miltenburg","sequence":"additional","affiliation":[{"name":"Department of Chemistry"},{"name":"University of Toronto"},{"name":"Toronto"},{"name":"Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5230-7475","authenticated-orcid":false,"given":"Aaron R.","family":"Wheeler","sequence":"additional","affiliation":[{"name":"Department of Chemistry"},{"name":"University of Toronto"},{"name":"Toronto"},{"name":"Canada"},{"name":"Donnelly Centre for Cellular and Biomolecular Research"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2016]]},"reference":[{"issue":"7101","key":"C6LC01064D-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1038\/nature05064","volume":"442","author":"Yager","year":"2006","journal-title":"Nature"},{"issue":"6","key":"C6LC01064D-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1097\/01.CCM.0000217961.75225.E9","volume":"34","author":"Kumar","year":"2006","journal-title":"Crit. Care Med."},{"issue":"1","key":"C6LC01064D-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1093\/cid\/cit641","volume":"58","author":"Kabanda","year":"2013","journal-title":"Clin. Infect. Dis."},{"issue":"3","key":"C6LC01064D-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S1473-3099(11)70251-1","volume":"12","author":"Lawn","year":"2012","journal-title":"Lancet Infect. Dis."},{"issue":"1","key":"C6LC01064D-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1021\/ac9013989","volume":"82","author":"Martinez","year":"2010","journal-title":"Anal. Chem."},{"issue":"1","key":"C6LC01064D-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"11301","DOI":"10.1063\/1.3687398","volume":"6","author":"Li","year":"2012","journal-title":"Biomicrofluidics"},{"issue":"21","key":"C6LC01064D-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4321","DOI":"10.1039\/c2lc40785j","volume":"12","author":"Fridley","year":"2012","journal-title":"Lab Chip"},{"issue":"10","key":"C6LC01064D-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3699","DOI":"10.1021\/ac800112r","volume":"80","author":"Martinez","year":"2008","journal-title":"Anal. Chem."},{"issue":"8","key":"C6LC01064D-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1038\/nm.2408","volume":"17","author":"Chin","year":"2011","journal-title":"Nat. Med."},{"issue":"50","key":"C6LC01064D-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"19606","DOI":"10.1073\/pnas.0810903105","volume":"105","author":"Martinez","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"7","key":"C6LC01064D-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1039\/b919614e","volume":"10","author":"Fu","year":"2010","journal-title":"Lab Chip"},{"issue":"23","key":"C6LC01064D-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9131","DOI":"10.1021\/ac801729t","volume":"80","author":"Li","year":"2008","journal-title":"Anal. Chem."},{"issue":"1","key":"C6LC01064D-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1039\/C1LC20622B","volume":"12","author":"Govindarajan","year":"2012","journal-title":"Lab Chip"},{"issue":"1","key":"C6LC01064D-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1146\/annurev-anchem-062011-143028","volume":"5","author":"Choi","year":"2012","journal-title":"Annu. Rev. Anal. Chem."},{"issue":"20","key":"C6LC01064D-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9638","DOI":"10.1021\/ac401847x","volume":"85","author":"Choi","year":"2013","journal-title":"Anal. Chem."},{"issue":"20","key":"C6LC01064D-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8805","DOI":"10.1021\/ac3020627","volume":"84","author":"Ng","year":"2012","journal-title":"Anal. Chem."},{"issue":"3","key":"C6LC01064D-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1139\/cjc-2013-0506","volume":"92","author":"Mudrik","year":"2014","journal-title":"Can. J. Chem."},{"issue":"46","key":"C6LC01064D-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8625","DOI":"10.1002\/anie.201001604","volume":"49","author":"Jebrail","year":"2010","journal-title":"Angew. Chem., Int. Ed."},{"issue":"3","key":"C6LC01064D-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1556\/JFC-D-12-00012","volume":"2","author":"Jebrail","year":"2012","journal-title":"J. Flow Chem."},{"issue":"3","key":"C6LC01064D-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1073\/pnas.1117566109","volume":"109","author":"Keng","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"10","key":"C6LC01064D-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1039\/C3CC47616B","volume":"50","author":"Javed","year":"2014","journal-title":"Chem. Commun."},{"issue":"1","key":"C6LC01064D-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.aca.2003.12.030","volume":"507","author":"Srinivasan","year":"2004","journal-title":"Anal. Chim. Acta"},{"issue":"12","key":"C6LC01064D-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6121","DOI":"10.1021\/ac5012969","volume":"86","author":"Kirby","year":"2014","journal-title":"Anal. Chem."},{"issue":"18","key":"C6LC01064D-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3776","DOI":"10.1039\/C5LC00660K","volume":"15","author":"Rackus","year":"2015","journal-title":"Lab Chip"},{"issue":"15","key":"C6LC01064D-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5129","DOI":"10.1039\/C5AN00500K","volume":"140","author":"Lei","year":"2015","journal-title":"Analyst"},{"key":"C6LC01064D-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.bios.2012.10.035","volume":"42","author":"Shih","year":"2013","journal-title":"Biosens. Bioelectron."},{"key":"C6LC01064D-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3355","DOI":"10.1038\/ncomms4355","volume":"5","author":"Eydelnant","year":"2014","journal-title":"Nat. Commun."},{"key":"C6LC01064D-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7513","DOI":"10.1038\/ncomms8513","volume":"6","author":"Ng","year":"2015","journal-title":"Nat. Commun."},{"issue":"13","key":"C6LC01064D-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2212","DOI":"10.1039\/c1lc20111e","volume":"11","author":"Park","year":"2011","journal-title":"Lab Chip"},{"issue":"4","key":"C6LC01064D-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s10404-007-0190-3","volume":"4","author":"Abdelgawad","year":"2007","journal-title":"Microfluid. Nanofluid."},{"key":"C6LC01064D-(cit31)\/*[position()=1]","first-page":"1","author":"Yafia","year":"2015","journal-title":"J. Micromech. Microeng."},{"issue":"22","key":"C6LC01064D-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7877","DOI":"10.1021\/ac0613378","volume":"78","author":"Watson","year":"2006","journal-title":"Anal. Chem."},{"issue":"5","key":"C6LC01064D-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1007\/s10404-014-1345-7","volume":"16","author":"Abadian","year":"2014","journal-title":"Microfluid. Nanofluid."},{"issue":"15","key":"C6LC01064D-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1002\/adma.201305014","volume":"26","author":"Ko","year":"2014","journal-title":"Adv. Mater."},{"issue":"18","key":"C6LC01064D-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2838","DOI":"10.1002\/adma.201305168","volume":"26","author":"Fobel","year":"2014","journal-title":"Adv. Mater."},{"issue":"2","key":"C6LC01064D-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1373\/clinchem.2014.232181","volume":"61","author":"Ng","year":"2015","journal-title":"Clin. Chem."},{"issue":"2","key":"C6LC01064D-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1039\/C1LC20782B","volume":"12","author":"Liedert","year":"2012","journal-title":"Lab Chip"},{"issue":"19","key":"C6LC01064D-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"193513","DOI":"10.1063\/1.4807118","volume":"102","author":"Fobel","year":"2013","journal-title":"Appl. Phys. Lett."},{"key":"C6LC01064D-(cit39)\/*[position()=1]","author":"Fobel","year":"2016","unstructured":"R.\n            Fobel\n          , I.Swyer, M.Ho and A. R.Wheeler, 2016"},{"issue":"5","key":"C6LC01064D-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.jeurceramsoc.2008.07.016","volume":"29","author":"Stringer","year":"2009","journal-title":"J. Eur. Ceram. Soc."},{"issue":"9","key":"C6LC01064D-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1007\/s11664-007-0194-5","volume":"36","author":"Jung","year":"2007","journal-title":"J. Electron. Mater."},{"issue":"6","key":"C6LC01064D-(cit42)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"H195","DOI":"10.1149\/1.3098962","volume":"12","author":"Kim","year":"2009","journal-title":"Electrochem. Solid-State Lett."},{"issue":"9","key":"C6LC01064D-(cit43)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2925","DOI":"10.1039\/C4EE01223B","volume":"7","author":"Andersen","year":"2014","journal-title":"Energy Environ. Sci."},{"issue":"48","key":"C6LC01064D-(cit44)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8007","DOI":"10.1039\/c3tc31708k","volume":"1","author":"Lin","year":"2013","journal-title":"J. Mater. Chem. C"},{"key":"C6LC01064D-(cit45)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.solmat.2015.04.007","volume":"140","author":"Dam","year":"2015","journal-title":"Sol. Energy Mater. Sol. Cells"},{"key":"C6LC01064D-(cit46)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.snb.2014.03.112","volume":"199","author":"Chen","year":"2014","journal-title":"Sens. Actuators, B"},{"issue":"7","key":"C6LC01064D-(cit47)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4080","DOI":"10.1063\/1.1504171","volume":"92","author":"Moon","year":"2002","journal-title":"J. Appl. Phys."},{"issue":"2","key":"C6LC01064D-(cit48)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1002\/aenm.201200520","volume":"3","author":"Angmo","year":"2012","journal-title":"Adv. Energy Mater."},{"issue":"19","key":"C6LC01064D-(cit49)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6032","DOI":"10.1039\/c2nr31508d","volume":"4","author":"Yu","year":"2012","journal-title":"Nanoscale"},{"issue":"9415","key":"C6LC01064D-(cit50)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/S0140-6736(04)15897-2","volume":"363","author":"Banatvala","year":"2004","journal-title":"Lancet"},{"issue":"Suppl 2","key":"C6LC01064D-(cit51)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"S652","DOI":"10.1093\/infdis\/jir405","volume":"204","author":"Bispo de Filippis","year":"2011","journal-title":"J. Infect. Dis."},{"issue":"3","key":"C6LC01064D-(cit52)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1128\/CVI.00688-12","volume":"20","author":"Enders","year":"2013","journal-title":"Clin. Vaccine Immunol."},{"issue":"Supplement 1","key":"C6LC01064D-(cit53)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"S506","DOI":"10.1093\/infdis\/jir117","volume":"204","author":"Rota","year":"2011","journal-title":"J. Infect. Dis."},{"issue":"2","key":"C6LC01064D-(cit54)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1093\/ajcp\/106.2.170","volume":"106","author":"Skendzel","year":"1996","journal-title":"Am. J. Clin. Pathol."}],"container-title":["Lab on a Chip"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2016\/LC\/C6LC01064D","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T17:28:08Z","timestamp":1782926888000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/lc\/article\/16\/23\/4560-4568\/525989"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":54,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.1039\/c6lc01064d","relation":{},"ISSN":["1473-0197","1473-0189"],"issn-type":[{"value":"1473-0197","type":"print"},{"value":"1473-0189","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Supplementary Information","URL":"https:\/\/doi.org\/10.1039\/C6LC01064D","name":"related_data","group":{"name":"related_data","label":"RELATED DATA"}},{"value":"Christopher Dixon (ResearcherID)","URL":"http:\/\/www.researcherid.com\/rid\/M-1506-2016","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Aaron R. Wheeler (ORCID)","URL":"http:\/\/orcid.org\/0000-0001-5230-7475","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"The Royal Society of Chemistry has an exclusive publication licence for this journal","name":"copyright_licence","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 24 August 2016; Accepted 21 October 2016;  Advance Article published 1 November 2016;  Version of Record published 15 November 2016","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}