{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T09:37:22Z","timestamp":1792661842809,"version":"4.5.0"},"reference-count":52,"publisher":"Royal Society of Chemistry (RSC)","issue":"23","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["61376120"],"award-info":[{"award-number":["61376120"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Lab Chip"],"abstract":"<p>A microfluidic particle separation platform featuring anti-clogging, degassing and multi-filtration functions for enhanced separation performance and operational stability.<\/p>","DOI":"10.1039\/c6lc01113f","type":"journal-article","created":{"date-parts":[[2016,10,17]],"date-time":"2016-10-17T11:53:40Z","timestamp":1476705220000},"page":"4517-4526","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["A bubble- and clogging-free microfluidic particle separation platform with multi-filtration"],"prefix":"10.1039","volume":"16","author":[{"given":"Yinuo","family":"Cheng","sequence":"first","affiliation":[{"name":"State Key Laboratory of Precision Measurement Technology and Instruments"},{"name":"Department of Precision Instruments"},{"name":"Tsinghua University"},{"name":"Beijing"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Precision Measurement Technology and Instruments"},{"name":"Department of Precision Instruments"},{"name":"Tsinghua University"},{"name":"Beijing"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zengshuai","family":"Ma","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Precision Measurement Technology and Instruments"},{"name":"Department of Precision Instruments"},{"name":"Tsinghua University"},{"name":"Beijing"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5884-6098","authenticated-orcid":false,"given":"Wenhui","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Precision Measurement Technology and Instruments"},{"name":"Department of Precision Instruments"},{"name":"Tsinghua University"},{"name":"Beijing"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiongying","family":"Ye","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Precision Measurement Technology and Instruments"},{"name":"Department of Precision Instruments"},{"name":"Tsinghua University"},{"name":"Beijing"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2016]]},"reference":[{"key":"C6LC01113F-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1007\/s11517-010-0611-4","volume":"48","author":"Bhagat","year":"2010","journal-title":"Med. Biol. Eng. Comput."},{"key":"C6LC01113F-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1002\/smll.201302907","volume":"10","author":"Yu","year":"2014","journal-title":"Small"},{"key":"C6LC01113F-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.chroma.2007.05.064","volume":"1162","author":"Zheng","year":"2007","journal-title":"J. Chromatogr. A"},{"key":"C6LC01113F-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1002\/bit.24471","volume":"109","author":"Hosokawa","year":"2012","journal-title":"Biotechnol. Bioeng."},{"key":"C6LC01113F-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3130","DOI":"10.1039\/c1lc20353c","volume":"11","author":"Schirhagl","year":"2011","journal-title":"Lab Chip"},{"key":"C6LC01113F-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2858","DOI":"10.1039\/c1lc20080a","volume":"11","author":"Aran","year":"2011","journal-title":"Lab Chip"},{"key":"C6LC01113F-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1039\/C0LC00121J","volume":"11","author":"Wei","year":"2011","journal-title":"Lab Chip"},{"key":"C6LC01113F-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1039\/b922301k","volume":"10","author":"Kuo","year":"2010","journal-title":"Lab Chip"},{"key":"C6LC01113F-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5692","DOI":"10.1021\/ac400167x","volume":"85","author":"Hosokawa","year":"2013","journal-title":"Anal. Chem."},{"key":"C6LC01113F-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1039\/b712784g","volume":"7","author":"Pamme","year":"2007","journal-title":"Lab Chip"},{"key":"C6LC01113F-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1039\/b300450c","volume":"3","author":"Moorthy","year":"2003","journal-title":"Lab Chip"},{"key":"C6LC01113F-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1039\/C4LC00350K","volume":"14","author":"Li","year":"2014","journal-title":"Lab Chip"},{"key":"C6LC01113F-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1039\/c1lc20089e","volume":"11","author":"Liu","year":"2011","journal-title":"Lab Chip"},{"key":"C6LC01113F-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1109\/JMEMS.2007.910241","volume":"16","author":"Meng","year":"2007","journal-title":"J. Microelectromech. Syst."},{"key":"C6LC01113F-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"014102","DOI":"10.1063\/1.4863355","volume":"8","author":"Kang","year":"2014","journal-title":"Biomicrofluidics"},{"key":"C6LC01113F-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1007\/s10544-009-9286-8","volume":"11","author":"Sung","year":"2009","journal-title":"Biomed. Microdevices"},{"key":"C6LC01113F-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1088\/0960-1317\/15\/5\/005","volume":"15","author":"Christensen","year":"2005","journal-title":"J. Micromech. Microeng."},{"key":"C6LC01113F-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1002\/(SICI)1522-2683(20000101)21:1<27::AID-ELPS27>3.0.CO;2-C","volume":"21","author":"Mcdonald","year":"2000","journal-title":"Electrophoresis"},{"key":"C6LC01113F-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0021-9797(90)90038-P","volume":"137","author":"Morra","year":"1990","journal-title":"J. Colloid Interface Sci."},{"key":"C6LC01113F-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1063\/1.1537519","volume":"82","author":"Anna","year":"2003","journal-title":"Appl. Phys. Lett."},{"key":"C6LC01113F-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4575","DOI":"10.1063\/1.1813871","volume":"16","author":"Cubaud","year":"2004","journal-title":"Phys. Fluids"},{"key":"C6LC01113F-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1039\/b510841a","volume":"6","author":"Garstecki","year":"2006","journal-title":"Lab Chip"},{"key":"C6LC01113F-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"054503","DOI":"10.1103\/PhysRevLett.92.054503","volume":"92","author":"Link","year":"2004","journal-title":"Phys. Rev. Lett."},{"key":"C6LC01113F-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1088\/0960-1317\/17\/5\/021","volume":"17","author":"Xiong","year":"2007","journal-title":"J. Micromech. Microeng."},{"key":"C6LC01113F-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3227","DOI":"10.1002\/aic.10276","volume":"50","author":"Yasuno","year":"2004","journal-title":"AIChE J."},{"key":"C6LC01113F-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1039\/b807037g","volume":"8","author":"Skelley","year":"2008","journal-title":"Lab Chip"},{"key":"C6LC01113F-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.jpowsour.2009.03.030","volume":"192","author":"Paust","year":"2009","journal-title":"J. Power Sources"},{"key":"C6LC01113F-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1088\/0960-1317\/14\/7\/006","volume":"14","author":"Jensen","year":"2004","journal-title":"J. Micromech. Microeng."},{"key":"C6LC01113F-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1109\/JMEMS.2009.2021826","volume":"18","author":"Yang","year":"2009","journal-title":"J. Microelectromech. Syst."},{"key":"C6LC01113F-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.cej.2007.07.037","volume":"135","author":"van Steijn","year":"2007","journal-title":"Chem. Eng. J."},{"key":"C6LC01113F-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2906","DOI":"10.1039\/c005274d","volume":"10","author":"Zheng","year":"2010","journal-title":"Lab Chip"},{"key":"C6LC01113F-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1021\/ac0490088","volume":"77","author":"Hibara","year":"2005","journal-title":"Anal. Chem."},{"key":"C6LC01113F-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1039\/c3lc51307f","volume":"14","author":"Yue","year":"2014","journal-title":"Lab Chip"},{"key":"C6LC01113F-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1039\/C1LC20817A","author":"Lochovsky","year":"2012","journal-title":"Lab Chip"},{"key":"C6LC01113F-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1088\/0960-1317\/13\/5\/332","volume":"13","author":"Shin","year":"2003","journal-title":"J. Micromech. Microeng."},{"key":"C6LC01113F-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.snb.2005.03.049","volume":"113","author":"Prakash","year":"2006","journal-title":"Sens. Actuators, B"},{"key":"C6LC01113F-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.1088\/0960-1317\/17\/10\/018","volume":"17","author":"Liu","year":"2007","journal-title":"J. Micromech. Microeng."},{"key":"C6LC01113F-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1007\/s00216-006-0688-7","volume":"386","author":"Nakayama","year":"2006","journal-title":"Anal. Bioanal. Chem."},{"key":"C6LC01113F-(cit39)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s10544-005-6073-z","volume":"7","author":"Wang","year":"2005","journal-title":"Biomed. Microdevices"},{"key":"C6LC01113F-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4366","DOI":"10.1039\/c3lc50778e","volume":"13","author":"Karlsson","year":"2013","journal-title":"Lab Chip"},{"key":"C6LC01113F-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1007\/s10404-010-0592-5","volume":"9","author":"Xu","year":"2010","journal-title":"Microfluid. Nanofluid."},{"key":"C6LC01113F-(cit42)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1088\/0960-1317\/16\/2\/028","volume":"16","author":"Meng","year":"2006","journal-title":"J. Micromech. Microeng."},{"key":"C6LC01113F-(cit43)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1039\/b719918j","volume":"8","author":"Meng","year":"2008","journal-title":"Lab Chip"},{"key":"C6LC01113F-(cit44)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1007\/s00542-009-0903-5","volume":"15","author":"Zhu","year":"2009","journal-title":"Microsyst. Technol."},{"key":"C6LC01113F-(cit45)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1002\/(SICI)1099-0488(20000201)38:3<415::AID-POLB8>3.0.CO;2-Z","volume":"38","author":"Merkel","year":"2000","journal-title":"J. Polym. Sci., Part B: Polym. Phys."},{"key":"C6LC01113F-(cit46)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2615","DOI":"10.1039\/c3lc50181g","volume":"13","author":"Didar","year":"2013","journal-title":"Lab Chip"},{"key":"C6LC01113F-(cit47)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2657","DOI":"10.1039\/C4LC00306C","volume":"14","author":"Beattie","year":"2014","journal-title":"Lab Chip"},{"key":"C6LC01113F-(cit48)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2278","DOI":"10.1039\/C5LC00226E","volume":"15","author":"Qin","year":"2015","journal-title":"Lab Chip"},{"key":"C6LC01113F-(cit49)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"26531","DOI":"10.1038\/srep26531","volume":"6","author":"Yoon","year":"2016","journal-title":"Sci. Rep."},{"key":"C6LC01113F-(cit50)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"014118","DOI":"10.1063\/1.4941985","volume":"10","author":"Cheng","year":"2016","journal-title":"Biomicrofluidics"},{"key":"C6LC01113F-(cit51)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1063\/1.1878340","volume":"57","author":"Widom","year":"2004","journal-title":"Phys. Today"},{"key":"C6LC01113F-(cit52)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3249","DOI":"10.1007\/s00216-010-3721-9","volume":"397","author":"Gossett","year":"2010","journal-title":"Anal. Bioanal. Chem."}],"container-title":["Lab on a Chip"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2016\/LC\/C6LC01113F","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:27:18Z","timestamp":1782883638000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/lc\/article\/16\/23\/4517-4526\/526008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":52,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.1039\/c6lc01113f","relation":{},"ISSN":["1473-0197","1473-0189"],"issn-type":[{"value":"1473-0197","type":"print"},{"value":"1473-0189","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Wenhui Wang (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-5884-6098","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"The Royal Society of Chemistry has an exclusive publication licence for this journal","name":"copyright_licence","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 6 September 2016; Accepted 13 October 2016;  Accepted Manuscript published 17 October 2016;  Advance Article published 28 October 2016;  Version of Record published 15 November 2016","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}