{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T07:42:56Z","timestamp":1782891776237,"version":"3.54.5"},"reference-count":31,"publisher":"Royal Society of Chemistry (RSC)","funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"crossref","award":["Excellence Cluster Tailor-Made Fuels from Biomass"],"award-info":[{"award-number":["Excellence Cluster Tailor-Made Fuels from Biomass"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Faraday Discuss."],"abstract":"<p>\n                    In recent years, lignin valorization has gained upward momentum owing to advances in both plant bioengineering and catalytic processing of lignin. In this new horizon, catalysis is now applied to the \u2018pulping process\u2019 itself, creating efficient methods for lignocellulose fractionation or deconstruction (here referred to as Catalytic Upstream Biorefining or \u2018CUB\u2019). These processes render, together with delignified pulps, lignin streams of low molecular weight (\n                    <italic>M<\/italic>\n                    <sub>w<\/sub>\n                    ) and low molecular diversity. Recently, we introduced a CUB process based on Early-stage Catalytic Conversion of Lignin (ECCL) through H-transfer reactions catalyzed by RANEY\u00ae Ni. This approach renders a lignin stream obtained as a viscous oil, comprising up to 60 wt% monophenolic compounds (\n                    <italic>M<\/italic>\n                    <sub>w<\/sub>\n                    &lt; 250 Da). The remaining oil fraction (40 wt%) is mainly composed of lignin oligomers, and as minor products, holocellulose-derived polyols and lignin-derived species of high\n                    <italic>M<\/italic>\n                    <sub>w<\/sub>\n                    (0.25\u20132 kDa). Simultaneously, the process yields a holocellulose pulp with a low content of residual lignin (&lt;5 wt%). Despite the efficiency of aqueous solutions of 2-propanol as a solvent for lignin fragments and an H-donor, there is scant information regarding the CUB process carried out in the presence of primary alcohols, which often inhibit the catalytic activity of RANEY\u00ae Ni, as revealed in model compound studies performed at low temperature. Considering the composition of the lignin oils obtained from CUB based on ECCL, the processes commonly render\n                    <italic>ortho<\/italic>\n                    -(di)methoxy-4-propylphenol derivatives with a varied degree of defunctionalization of the propyl side chain. In this contribution, we present the role of the alcohol solvent (methanol or 2-propanol) and Ni catalyst (Ni\/C or RANEY\u00ae Ni) in control over selectivity of phenolic products. The current results indicate that solvent effects on the catalytic processes could hold the key for improving control over the degree of functionalization of the propyl side-chain in the lignin oil obtained from CUB, offering new avenues for lignin valorization at the extraction step.\n                  <\/p>","DOI":"10.1039\/c7fd00069c","type":"journal-article","created":{"date-parts":[[2017,4,19]],"date-time":"2017-04-19T10:23:45Z","timestamp":1492597425000},"page":"403-413","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Effect of methanol in controlling defunctionalization of the propyl side chain of phenolics from catalytic upstream biorefining"],"prefix":"10.1039","volume":"202","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8576-1228","authenticated-orcid":false,"given":"Paola","family":"Ferrini","sequence":"first","affiliation":[{"name":"Max-Planck-Institut f\u00fcr Kohlenforschung"},{"name":"45470 M\u00fclheim (Ruhr)"},{"name":"Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Chesi","sequence":"additional","affiliation":[{"name":"Imperial College London"},{"name":"Department of Chemical Engineering"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Parkin","sequence":"additional","affiliation":[{"name":"Imperial College London"},{"name":"Department of Chemical Engineering"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7175-4972","authenticated-orcid":false,"given":"Roberto","family":"Rinaldi","sequence":"additional","affiliation":[{"name":"Imperial College London"},{"name":"Department of Chemical Engineering"},{"name":"UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2017]]},"reference":[{"key":"C7FD00069C-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8164","DOI":"10.1002\/anie.201510351","volume":"55","author":"Rinaldi","year":"2016","journal-title":"Angew. 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