{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T04:08:09Z","timestamp":1782965289803,"version":"3.54.5"},"reference-count":40,"publisher":"Royal Society of Chemistry (RSC)","issue":"14","content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Lab Chip"],"abstract":"<p>An encoded viral micropatch is presented for localized target gene expression for high-throughput, high-content cell-based assays.<\/p>","DOI":"10.1039\/c7lc00372b","type":"journal-article","created":{"date-parts":[[2017,5,30]],"date-time":"2017-05-30T03:53:08Z","timestamp":1496116388000},"page":"2435-2442","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["An encoded viral micropatch for multiplex cell-based assays through localized gene delivery"],"prefix":"10.1039","volume":"17","author":[{"given":"Sangkwon","family":"Han","sequence":"first","affiliation":[{"name":"QuantaMatrix Inc."},{"name":"Seoul National University Hospital"},{"name":"Seoul"},{"name":"South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyung Jong","family":"Bae","sequence":"additional","affiliation":[{"name":"Nano Systems Institute"},{"name":"Seoul National University"},{"name":"Seoul 08826"},{"name":"South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su Deok","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Electrical and Computer Engineering"},{"name":"Seoul National University"},{"name":"Seoul 08826"},{"name":"South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wook","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Electronics Engineering"},{"name":"Kyung Hee University"},{"name":"South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3514-1738","authenticated-orcid":false,"given":"Sunghoon","family":"Kwon","sequence":"additional","affiliation":[{"name":"QuantaMatrix Inc."},{"name":"Seoul National University Hospital"},{"name":"Seoul"},{"name":"South Korea"},{"name":"Nano Systems Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2017]]},"reference":[{"key":"C7LC00372B-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0958-1669(99)00051-8","volume":"11","author":"Sundberg","year":"2000","journal-title":"Curr. Opin. Biotechnol."},{"key":"C7LC00372B-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1038\/nchembio.2007.17","volume":"3","author":"Inglese","year":"2007","journal-title":"Nat. Chem. Biol."},{"key":"C7LC00372B-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.drudis.2006.05.015","volume":"11","author":"Castel","year":"2006","journal-title":"Drug Discovery Today"},{"key":"C7LC00372B-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S0167-7799(02)01906-6","volume":"20","author":"Croston","year":"2002","journal-title":"Trends Biotechnol."},{"key":"C7LC00372B-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/s00216-010-3933-z","volume":"398","author":"Michelini","year":"2010","journal-title":"Anal. Bioanal. Chem."},{"key":"C7LC00372B-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"S131","DOI":"10.1016\/S1359-6446(02)02388-7","volume":"7","author":"Beske","year":"2002","journal-title":"Drug Discovery Today"},{"key":"C7LC00372B-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3739","DOI":"10.1038\/ncomms4739","volume":"5","author":"Kwon","year":"2014","journal-title":"Nat. Commun."},{"key":"C7LC00372B-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4939-0594-2","volume-title":"Cell-Based Microarrays: Review of Applications, Developments and Technological Advances","author":"Palmer","year":"2014","unstructured":"E. Palmer , Cell-Based Microarrays: Review of Applications, Developments and Technological Advances, Springer Science & Business Media, 2014"},{"key":"C7LC00372B-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1038\/nbt746","volume":"20","author":"Michiels","year":"2002","journal-title":"Nat. Biotechnol."},{"key":"C7LC00372B-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1038\/nature04687","volume":"441","author":"Ngo","year":"2006","journal-title":"Nature"},{"key":"C7LC00372B-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1517\/17460440902751599","volume":"4","author":"Ames","year":"2009","journal-title":"Expert Opin. Drug Discovery"},{"key":"C7LC00372B-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/nmeth848","volume":"3","author":"Bailey","year":"2006","journal-title":"Nat. Methods"},{"key":"C7LC00372B-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2244","DOI":"10.1016\/j.biomaterials.2006.12.026","volume":"28","author":"Carbone","year":"2007","journal-title":"Biomaterials"},{"key":"C7LC00372B-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1186\/1471-2164-9-441","volume":"9","author":"Oehmig","year":"2008","journal-title":"BMC Genomics"},{"key":"C7LC00372B-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"255","DOI":"10.2144\/000113748","volume":"51","author":"McConnell","year":"2011","journal-title":"BioTechniques"},{"key":"C7LC00372B-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"rs4","DOI":"10.1126\/scisignal.2002612","volume":"5","author":"Wood","year":"2012","journal-title":"Sci. Signaling"},{"key":"C7LC00372B-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1186\/1756-0500-5-358","volume":"5","author":"Fengler","year":"2012","journal-title":"BMC Res. Notes"},{"key":"C7LC00372B-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.bios.2015.04.024","volume":"76","author":"Berthuy","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"C7LC00372B-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0167-7799(01)01844-3","volume":"20","author":"Nolan","year":"2002","journal-title":"Trends Biotechnol."},{"key":"C7LC00372B-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6104","DOI":"10.1002\/anie.200600288","volume":"45","author":"Wilson","year":"2006","journal-title":"Angew. Chem., Int. Ed."},{"key":"C7LC00372B-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1126\/science.1134929","volume":"315","author":"Pregibon","year":"2007","journal-title":"Science"},{"key":"C7LC00372B-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1021\/ac1022343","volume":"83","author":"Appleyard","year":"2011","journal-title":"Anal. Chem."},{"key":"C7LC00372B-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2289","DOI":"10.1002\/anie.201006523","volume":"50","author":"Chapin","year":"2011","journal-title":"Angew. Chem., Int. Ed."},{"key":"C7LC00372B-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3468","DOI":"10.1038\/ncomms4468","volume":"5","author":"Chung","year":"2014","journal-title":"Nat. Commun."},{"key":"C7LC00372B-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"12130","DOI":"10.1039\/C5CC02048D","volume":"51","author":"Kim","year":"2015","journal-title":"Chem. Commun."},{"key":"C7LC00372B-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1039\/C6LC01268J","volume":"7","author":"Song","year":"2017","journal-title":"Lab Chip"},{"key":"C7LC00372B-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2716","DOI":"10.1002\/adfm.200800255","volume":"18","author":"Fayazpour","year":"2008","journal-title":"Adv. Funct. Mater."},{"key":"C7LC00372B-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1038\/nrd2008","volume":"5","author":"Lang","year":"2006","journal-title":"Nat. Rev. Drug Discovery"},{"key":"C7LC00372B-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1038\/nrd2876","volume":"8","author":"Feng","year":"2009","journal-title":"Nat. Rev. Drug Discovery"},{"key":"C7LC00372B-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.tibtech.2010.02.005","volume":"28","author":"Zanella","year":"2010","journal-title":"Trends Biotechnol."},{"key":"C7LC00372B-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1002\/jgm.1233","volume":"10","author":"Hu","year":"2008","journal-title":"J. Gene Med."},{"key":"C7LC00372B-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"R100","DOI":"10.1186\/gb-2006-7-10-r100","volume":"7","author":"Carpenter","year":"2006","journal-title":"Genome Biol."},{"key":"C7LC00372B-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1177\/1087057107312128","volume":"13","author":"Haasen","year":"2008","journal-title":"J. Biomol. Screening"},{"key":"C7LC00372B-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5162","DOI":"10.1364\/OL.39.005162","volume":"39","author":"Song","year":"2014","journal-title":"Opt. Lett."},{"key":"C7LC00372B-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8426","DOI":"10.3390\/s120608426","volume":"12","author":"Park","year":"2012","journal-title":"Sensors"},{"key":"C7LC00372B-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7085","DOI":"10.1128\/JVI.74.15.7085-7095.2000","volume":"74","author":"Nakano","year":"2000","journal-title":"J. Virol."},{"key":"C7LC00372B-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1038\/sj.gt.3302420","volume":"12","author":"Pandori","year":"2005","journal-title":"Gene Ther."},{"key":"C7LC00372B-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9706","DOI":"10.1128\/JVI.72.12.9706-9713.1998","volume":"72","author":"Dmitriev","year":"1998","journal-title":"J. Virol."},{"key":"C7LC00372B-(cit39)\/*[position()=1]","first-page":"655","volume":"16","author":"Thomsen","year":"2005","journal-title":"Curr. Opin. Biotechnol."},{"key":"C7LC00372B-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/S1359-6446(03)02738-7","volume":"8","author":"Milligan","year":"2003","journal-title":"Drug Discovery Today"}],"container-title":["Lab on a Chip"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2017\/LC\/C7LC00372B","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T03:40:48Z","timestamp":1782963648000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/lc\/article\/17\/14\/2435-2442\/568257"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":40,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.1039\/c7lc00372b","relation":{},"ISSN":["1473-0197","1473-0189"],"issn-type":[{"value":"1473-0197","type":"print"},{"value":"1473-0189","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Supplementary Information","URL":"https:\/\/doi.org\/10.1039\/C7LC00372B","name":"related_data","group":{"name":"related_data","label":"RELATED DATA"}},{"value":"Sunghoon Kwon (ORCID)","URL":"http:\/\/orcid.org\/0000-0003-3514-1738","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"The Royal Society of Chemistry has an exclusive publication licence for this journal","name":"copyright_licence","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 5 April 2017; Accepted 19 May 2017; Advance Article published 30 May 2017; Version of Record published 11 July 2017","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}