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Chem. Commun."],"abstract":"<p>\n                    The enzymes isocitrate lyase (ICL) isoforms 1 and 2 are essential for\n                    <italic>Mycobacterium tuberculosis<\/italic>\n                    survival within macrophages during latent tuberculosis (TB). Herein we report the development of a combined NMR spectroscopy and thermal shift assay for the screening and evaluation of ICL inhibitors.\n                  <\/p>","DOI":"10.1039\/c7md00456g","type":"journal-article","created":{"date-parts":[[2017,10,16]],"date-time":"2017-10-16T23:02:59Z","timestamp":1508194979000},"page":"2155-2163","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Development of NMR and thermal shift assays for the evaluation of\n                    <i>Mycobacterium tuberculosis<\/i>\n                    isocitrate lyase inhibitors"],"prefix":"10.1039","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2997-3995","authenticated-orcid":false,"given":"Ram Prasad","family":"Bhusal","sequence":"first","affiliation":[{"name":"School of Chemical Sciences"},{"name":"The University of Auckland"},{"name":"Auckland 1142"},{"name":"New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9796-804X","authenticated-orcid":false,"given":"Krunal","family":"Patel","sequence":"additional","affiliation":[{"name":"School of Chemical Sciences"},{"name":"The University of Auckland"},{"name":"Auckland 1142"},{"name":"New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6378-9633","authenticated-orcid":false,"given":"Brooke X. 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