{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T22:29:21Z","timestamp":1788560961994,"version":"build-2803163510"},"reference-count":44,"publisher":"Royal Society of Chemistry (RSC)","issue":"42","funder":[{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"crossref","award":["MOST 104-2221-E-007 -140 -MY2"],"award-info":[{"award-number":["MOST 104-2221-E-007 -140 -MY2"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"crossref","award":["MOST 104-2622-E-007-018 -CC2"],"award-info":[{"award-number":["MOST 104-2622-E-007-018 -CC2"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"crossref","award":["MOST 104-2628-E-007 -002 -MY3"],"award-info":[{"award-number":["MOST 104-2628-E-007 -002 -MY3"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Nanoscale"],"abstract":"<p>Functionalised self-assembling nanopeptide hydrogel mediates angiogenesis and neurogenesis for injured brain tissue regeneration.<\/p>","DOI":"10.1039\/c7nr06528k","type":"journal-article","created":{"date-parts":[[2017,10,6]],"date-time":"2017-10-06T04:03:02Z","timestamp":1507262582000},"page":"16281-16292","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":76,"title":["Effects of an injectable functionalized self-assembling nanopeptide hydrogel on angiogenesis and neurogenesis for regeneration of the central nervous system"],"prefix":"10.1039","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0669-6240","authenticated-orcid":false,"given":"Tzu-Wei","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Materials Science and Engineering"},{"name":"National Tsing Hua University"},{"name":"Hsinchu"},{"name":"Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai-Chieh","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Engineering"},{"name":"National Tsing Hua University"},{"name":"Hsinchu"},{"name":"Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang-Hsin","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Engineering"},{"name":"National Tsing Hua University"},{"name":"Hsinchu"},{"name":"Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih-Yung","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering and Environmental Sciences"},{"name":"National Tsing Hua University"},{"name":"Hsinchu"},{"name":"Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia-Wei","family":"Yeh","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Engineering"},{"name":"National Tsing Hua University"},{"name":"Hsinchu"},{"name":"Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yung-Jen","family":"Chuang","sequence":"additional","affiliation":[{"name":"Department of Medical Science & Institute of Bioinformatics and Structural Biology"},{"name":"National Tsing Hua University"},{"name":"Hsinchu"},{"name":"Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2017]]},"reference":[{"key":"C7NR06528K-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/S1474-4422(08)70164-9","volume":"7","author":"Maas","year":"2008","journal-title":"Lancet Neurol."},{"key":"C7NR06528K-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1097\/MCC.0b013e32807f2a94","volume":"13","author":"Servadei","year":"2007","journal-title":"Curr. Opin. Crit. Care"},{"key":"C7NR06528K-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/nature00900","volume":"418","author":"Kim","year":"2002","journal-title":"Nature"},{"key":"C7NR06528K-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1002\/ana.20501","volume":"57","author":"Bang","year":"2005","journal-title":"Ann. Neurol."},{"key":"C7NR06528K-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","DOI":"10.1016\/B978-0-444-53630-3.00008-7","volume-title":"Sex Differences in the Human Brain, Their Underpinnings and Implications","volume":"186","author":"Reddy","year":"2010","unstructured":"D. S. Reddy , in Sex Differences in the Human Brain, Their Underpinnings and Implications, ed. I. Savic, 2010, vol. 186, pp. 113\u2013137"},{"key":"C7NR06528K-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"175","DOI":"10.2217\/fnl.12.95","volume":"8","author":"\u00c1lvarez","year":"2013","journal-title":"Future Neurol."},{"key":"C7NR06528K-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/npp.2013.237","volume":"39","author":"Tam","year":"2014","journal-title":"Neuropsychopharmacology"},{"key":"C7NR06528K-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1038\/nrn2685","volume":"10","author":"Orive","year":"2009","journal-title":"Nat. Rev. Neurosci."},{"key":"C7NR06528K-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.biotechadv.2011.10.004","volume":"30","author":"Loo","year":"2012","journal-title":"Biotechnol. Adv."},{"issue":"8","key":"C7NR06528K-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1016\/j.biomaterials.2012.11.043","volume":"34","author":"Cheng","year":"2013","journal-title":"Biomaterials"},{"key":"C7NR06528K-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3043","DOI":"10.2147\/DDDT.S109545","volume":"10","author":"Zhou","year":"2016","journal-title":"Drug Des., Dev. Ther."},{"key":"C7NR06528K-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8414","DOI":"10.1073\/pnas.0407843102","volume":"102","author":"Yokoi","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"C7NR06528K-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7771","DOI":"10.1039\/C4TB01391C","volume":"2","author":"Rodriguez","year":"2014","journal-title":"J. Mater. Chem. B"},{"key":"C7NR06528K-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.actbio.2016.06.016","volume":"42","author":"Zweckberger","year":"2016","journal-title":"Acta Biomater."},{"issue":"8","key":"C7NR06528K-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.1016\/j.celrep.2017.07.069","volume":"20","author":"Somaa","year":"2017","journal-title":"Cell Rep."},{"key":"C7NR06528K-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"238","DOI":"10.2174\/157340310791658802","volume":"6","author":"Font","year":"2010","journal-title":"Curr. Cardiol. Rev."},{"key":"C7NR06528K-(cit17)\/*[position()=1]","first-page":"298","volume":"11","author":"Xiong","year":"2010","journal-title":"Curr. Opin. Invest. Drugs"},{"key":"C7NR06528K-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.matbio.2008.10.002","volume":"28","author":"Ito","year":"2009","journal-title":"Matrix Biol."},{"key":"C7NR06528K-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"36328","DOI":"10.1074\/jbc.274.51.36328","volume":"274","author":"Yokosaki","year":"1999","journal-title":"J. Biol. Chem."},{"key":"C7NR06528K-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"650","DOI":"10.4012\/dmj.23.650","volume":"23","author":"Hamada","year":"2004","journal-title":"Dent. Mater. J."},{"key":"C7NR06528K-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1093\/cvr\/cvt088","volume":"99","author":"Uchinaka","year":"2013","journal-title":"Cardiovasc. Res."},{"issue":"7","key":"C7NR06528K-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2734","DOI":"10.1039\/c3nr33710c","volume":"5","author":"Cheng","year":"2013","journal-title":"Nanoscale"},{"issue":"6","key":"C7NR06528K-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1021\/acsbiomaterials.6b00156","volume":"2","author":"Francis","year":"2016","journal-title":"ACS Biomater. Sci. Eng."},{"key":"C7NR06528K-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.actbio.2017.06.008","volume":"58","author":"Wang","year":"2017","journal-title":"Acta Biomater."},{"key":"C7NR06528K-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.addr.2016.06.013","volume":"110\u2013111","author":"Eskandari","year":"2017","journal-title":"Adv. Drug Delivery Rev."},{"key":"C7NR06528K-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0042-6989(02)00395-4","volume":"43","author":"Maaswinkel","year":"2003","journal-title":"Vision Res."},{"key":"C7NR06528K-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3792","DOI":"10.1021\/acs.biomac.5b01092","volume":"16","author":"Owczarz","year":"2015","journal-title":"Biomacromolecules"},{"key":"C7NR06528K-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1002\/adfm.200500161","volume":"16","author":"Stendahl","year":"2006","journal-title":"Adv. Funct. Mater."},{"key":"C7NR06528K-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.1002\/dvdy.22710","volume":"240","author":"Marz","year":"2011","journal-title":"Dev. Dyn."},{"key":"C7NR06528K-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1242\/dev.122796","volume":"143","author":"Alunni","year":"2016","journal-title":"Development"},{"key":"C7NR06528K-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/0006-8993(77)90166-4","volume":"128","author":"Springer","year":"1977","journal-title":"Brain Res."},{"key":"C7NR06528K-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1179\/016164101101199405","volume":"23","author":"Barbolt","year":"2001","journal-title":"Neurol. Res."},{"key":"C7NR06528K-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"367","DOI":"10.2217\/rme.14.9","volume":"9","author":"Meng","year":"2014","journal-title":"Regener. Med."},{"key":"C7NR06528K-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7454\/psr.v2i1.3481","volume":"10","author":"Ahmadi","year":"2015","journal-title":"Res. Pharm. Sci."},{"key":"C7NR06528K-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1039\/C5GC02396C","volume":"18","author":"Shen","year":"2016","journal-title":"Green Chem."},{"key":"C7NR06528K-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1007\/s10876-014-0836-8","volume":"26","author":"Aramvash","year":"2015","journal-title":"J. Cluster Sci."},{"key":"C7NR06528K-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1002\/psc.988","volume":"14","author":"Ye","year":"2008","journal-title":"J. Pept. Sci."},{"key":"C7NR06528K-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1021\/cr0302049","volume":"104","author":"Estroff","year":"2004","journal-title":"Chem. Rev."},{"key":"C7NR06528K-(cit39)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1016\/j.bpj.2012.03.012","volume":"102","author":"Arosio","year":"2012","journal-title":"Biophys. J."},{"key":"C7NR06528K-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6709","DOI":"10.1182\/blood-2011-06-359141","volume":"118","author":"Chan","year":"2011","journal-title":"Blood"},{"key":"C7NR06528K-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.bbrc.2003.09.001","volume":"310","author":"Hamada","year":"2003","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"C7NR06528K-(cit42)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.aquatox.2014.03.010","volume":"150","author":"Delov","year":"2014","journal-title":"Aquat. Toxicol."},{"key":"C7NR06528K-(cit43)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.reprotox.2014.05.014","volume":"48","author":"Tal","year":"2014","journal-title":"Reprod. Toxicol."},{"key":"C7NR06528K-(cit44)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1002\/stem.306","volume":"28","author":"Kojima","year":"2010","journal-title":"Stem Cells"}],"container-title":["Nanoscale"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2017\/NR\/C7NR06528K","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:54:41Z","timestamp":1782885281000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/nr\/article\/9\/42\/16281-16292\/573328"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":44,"journal-issue":{"issue":"42","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.1039\/c7nr06528k","relation":{},"ISSN":["2040-3364","2040-3372"],"issn-type":[{"value":"2040-3364","type":"print"},{"value":"2040-3372","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Supplementary Information","URL":"https:\/\/doi.org\/10.1039\/C7NR06528K","name":"related_data","group":{"name":"related_data","label":"RELATED DATA"}},{"value":"Tzu-Wei Wang (ORCID)","URL":"http:\/\/orcid.org\/0000-0003-0669-6240","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"The Royal Society of Chemistry has an exclusive publication licence for this journal","name":"copyright_licence","group":{"name":"copyright_licensing","label":"COPYRIGHT AND LICENSING"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 1 September 2017; Accepted 4 October 2017; Accepted Manuscript published 6 October 2017; Advance Article published 19 October 2017; Version of Record published 2 November 2017","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}