{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T08:32:52Z","timestamp":1782894772977,"version":"3.54.5"},"reference-count":48,"publisher":"Royal Society of Chemistry (RSC)","issue":"14","license":[{"start":{"date-parts":[[2019,6,8]],"date-time":"2019-06-08T00:00:00Z","timestamp":1559952000000},"content-version":"am","delay-in-days":523,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["21375063"],"award-info":[{"award-number":["21375063"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["21335004"],"award-info":[{"award-number":["21335004"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["21675088"],"award-info":[{"award-number":["21675088"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["21475118"],"award-info":[{"award-number":["21475118"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004706","name":"Zhejiang Normal University","doi-asserted-by":"crossref","award":["ZJHX2017"],"award-info":[{"award-number":["ZJHX2017"]}],"id":[{"id":"10.13039\/501100004706","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Analyst"],"abstract":"<p>A ratiometric electrochemiluminescence assay using CdS:Eu NCs and luminol as signal emitters was fabricated for detecting the human methyltransferase activity.<\/p>","DOI":"10.1039\/c8an00611c","type":"journal-article","created":{"date-parts":[[2018,6,7]],"date-time":"2018-06-07T20:04:15Z","timestamp":1528401855000},"page":"3353-3359","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Dual-signal ratiometric electrochemiluminescence assay for detecting the activity of human methyltransferase"],"prefix":"10.1039","volume":"143","author":[{"given":"Zhihui","family":"Guo","sequence":"first","affiliation":[{"name":"Jiangsu Key Laboratory of Biomedical Materials"},{"name":"Jiangsu Collaborative Innovation Center of Biomedical Functional Materials"},{"name":"National and Local Joint Engineering Research Center of Biomedical Functional Materials"},{"name":"Jiangsu Key Laboratory of New Power Batteries"},{"name":"College of Chemistry and Materials Science"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Qiao","sequence":"additional","affiliation":[{"name":"Jiangsu Key Laboratory of Biomedical Materials"},{"name":"Jiangsu Collaborative Innovation Center of Biomedical Functional Materials"},{"name":"National and Local Joint Engineering Research Center of Biomedical Functional Materials"},{"name":"Jiangsu Key Laboratory of New Power Batteries"},{"name":"College of Chemistry and Materials Science"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qunqun","family":"Guo","sequence":"additional","affiliation":[{"name":"Jiangsu Key Laboratory of Biomedical Materials"},{"name":"Jiangsu Collaborative Innovation Center of Biomedical Functional Materials"},{"name":"National and Local Joint Engineering Research Center of Biomedical Functional Materials"},{"name":"Jiangsu Key Laboratory of New Power Batteries"},{"name":"College of Chemistry and Materials Science"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4922-3745","authenticated-orcid":false,"given":"Hui","family":"Zhang","sequence":"additional","affiliation":[{"name":"Jiangsu Key Laboratory of Biomedical Materials"},{"name":"Jiangsu Collaborative Innovation Center of Biomedical Functional Materials"},{"name":"National and Local Joint Engineering Research Center of Biomedical Functional Materials"},{"name":"Jiangsu Key Laboratory of New Power Batteries"},{"name":"College of Chemistry and Materials Science"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenxin","family":"Cai","sequence":"additional","affiliation":[{"name":"Jiangsu Key Laboratory of Biomedical Materials"},{"name":"Jiangsu Collaborative Innovation Center of Biomedical Functional Materials"},{"name":"National and Local Joint Engineering Research Center of Biomedical Functional Materials"},{"name":"Jiangsu Key Laboratory of New Power Batteries"},{"name":"College of Chemistry and Materials Science"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7954-0573","authenticated-orcid":false,"given":"Jiu-Ju","family":"Feng","sequence":"additional","affiliation":[{"name":"Key Laboratory of the Ministry of Education for Advanced Catalysis Materials"},{"name":"College of Chemistry and Life Sciences"},{"name":"Zhejiang NormalUniversity"},{"name":"Jinhua 321004"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2018]]},"reference":[{"key":"C8AN00611C-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3003","DOI":"10.1021\/cr020373d","volume":"104","author":"Richter","year":"2004","journal-title":"Chem. Rev."},{"key":"C8AN00611C-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2506","DOI":"10.1021\/cr068083a","volume":"108","author":"Miao","year":"2008","journal-title":"Chem. Rev."},{"key":"C8AN00611C-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5321","DOI":"10.1021\/ac400992u","volume":"85","author":"Zhang","year":"2013","journal-title":"Anal. Chem."},{"key":"C8AN00611C-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"10707","DOI":"10.1002\/chem.201001173","volume":"16","author":"Ding","year":"2010","journal-title":"Chem. \u2013 Eur. J."},{"key":"C8AN00611C-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1016\/j.bios.2009.11.025","volume":"25","author":"Su","year":"2010","journal-title":"Biosens. Bioelectron."},{"key":"C8AN00611C-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.bios.2015.05.069","volume":"74","author":"Zhang","year":"2015","journal-title":"Biosens. Bioelectron."},{"key":"C8AN00611C-(cit7)\/*[position()=1]","first-page":"1977","volume":"26","author":"Yang","year":"2014","journal-title":"Prog. Chem."},{"key":"C8AN00611C-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2932","DOI":"10.1039\/C3CC49719D","volume":"50","author":"Zhang","year":"2014","journal-title":"Chem. Commun."},{"key":"C8AN00611C-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8179","DOI":"10.1021\/acs.analchem.6b01935","volume":"88","author":"Shao","year":"2016","journal-title":"Anal. Chem."},{"key":"C8AN00611C-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.bios.2012.05.002","volume":"38","author":"Li","year":"2012","journal-title":"Biosens. Bioelectron."},{"key":"C8AN00611C-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4360","DOI":"10.1038\/srep04360","volume":"4","author":"Ren","year":"2014","journal-title":"Sci. Rep."},{"key":"C8AN00611C-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5158","DOI":"10.1021\/ac500965p","volume":"86","author":"Cheng","year":"2014","journal-title":"Anal. Chem."},{"key":"C8AN00611C-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8424","DOI":"10.1021\/ja2015873","volume":"133","author":"Zhang","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"C8AN00611C-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1021\/ac0484880","volume":"77","author":"Aslan","year":"2005","journal-title":"Anal. Chem."},{"key":"C8AN00611C-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1021\/acs.analchem.5b03670","volume":"88","author":"Feng","year":"2016","journal-title":"Anal. Chem."},{"key":"C8AN00611C-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"14828","DOI":"10.1039\/C4CC06801G","volume":"50","author":"Hao","year":"2014","journal-title":"Chem. Commun."},{"key":"C8AN00611C-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.snb.2015.11.131","volume":"226","author":"Feng","year":"2016","journal-title":"Sens. Actuators, B"},{"key":"C8AN00611C-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3834","DOI":"10.1021\/ac403960g","volume":"86","author":"Zhang","year":"2014","journal-title":"Anal. Chem."},{"key":"C8AN00611C-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.foodchem.2012.04.082","volume":"135","author":"Zhang","year":"2012","journal-title":"Food Chem."},{"key":"C8AN00611C-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"12669","DOI":"10.1039\/C5CC03678J","volume":"51","author":"Zhao","year":"2015","journal-title":"Chem. Commun."},{"key":"C8AN00611C-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2823","DOI":"10.1021\/acs.analchem.6b03883","volume":"89","author":"Chen","year":"2014","journal-title":"Anal. Chem."},{"key":"C8AN00611C-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8427","DOI":"10.1039\/C6NR01912A","volume":"8","author":"Wu","year":"2016","journal-title":"Nanoscale"},{"key":"C8AN00611C-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7787","DOI":"10.1021\/acs.analchem.5b01445","volume":"15","author":"Lei","year":"2015","journal-title":"Anal. Chem."},{"key":"C8AN00611C-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0092-8674(00)81656-6","volume":"99","author":"Okano","year":"1999","journal-title":"Cell"},{"key":"C8AN00611C-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.talanta.2016.01.026","volume":"152","author":"Hong","year":"2016","journal-title":"Talanta"},{"key":"C8AN00611C-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.bios.2016.04.082","volume":"85","author":"Ji","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"C8AN00611C-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"14350","DOI":"10.1039\/C5CC05375G","volume":"51","author":"Liu","year":"2015","journal-title":"Chem. Commun."},{"key":"C8AN00611C-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"19673","DOI":"10.1074\/jbc.M112.443895","volume":"288","author":"Kilgore","year":"2013","journal-title":"J. Biol. Chem."},{"key":"C8AN00611C-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1126\/science.1063852","volume":"293","author":"Jones","year":"2001","journal-title":"Science"},{"key":"C8AN00611C-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/S0167-4781(02)00482-7","volume":"1577","author":"Yanagisawa","year":"2002","journal-title":"Biochim. Biophys. Acta"},{"key":"C8AN00611C-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"33002","DOI":"10.1074\/jbc.274.46.33002","volume":"274","author":"Pradhan","year":"1999","journal-title":"J. Biol. Chem."},{"key":"C8AN00611C-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1016\/j.chembiol.2015.05.019","volume":"7","author":"Furst","year":"2015","journal-title":"Chem. Biol."},{"key":"C8AN00611C-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.1093\/hmg\/9.16.2395","volume":"9","author":"Bestor","year":"2000","journal-title":"Hum. Mol. Genet."},{"key":"C8AN00611C-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"14985","DOI":"10.1073\/pnas.1417351111","volume":"111","author":"Furst","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"C8AN00611C-(cit35)\/*[position()=1]","first-page":"4415","volume":"9","author":"Girault","year":"2003","journal-title":"Clin. Cancer Res."},{"key":"C8AN00611C-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9566","DOI":"10.1021\/ac102296g","volume":"82","author":"Xu","year":"2010","journal-title":"Anal. Chem."},{"key":"C8AN00611C-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1039\/C1NR11470K","volume":"4","author":"Deng","year":"2012","journal-title":"Nanoscale"},{"key":"C8AN00611C-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6782","DOI":"10.1021\/la0104323","volume":"17","author":"Jana","year":"2001","journal-title":"Langmuir"},{"key":"C8AN00611C-(cit39)\/*[position()=1]","first-page":"1108","volume":"88","author":"Zhang","year":"2016","journal-title":"Anal. Chem."},{"key":"C8AN00611C-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1166\/jnn.2009.SE17","volume":"9","author":"Chen","year":"2009","journal-title":"J. Nanosci. Nanotechnol."},{"key":"C8AN00611C-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.bios.2015.10.015","volume":"77","author":"Yan","year":"2015","journal-title":"Biosens. Bioelectron."},{"key":"C8AN00611C-(cit42)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8556","DOI":"10.1021\/acs.analchem.6b01579","volume":"88","author":"Li","year":"2016","journal-title":"Anal. Chem."},{"key":"C8AN00611C-(cit43)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"16632","DOI":"10.1021\/ja4085918","volume":"135","author":"Muren","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"C8AN00611C-(cit44)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3537","DOI":"10.1039\/C4AN00336E","volume":"139","author":"Ma","year":"2014","journal-title":"Analyst"},{"key":"C8AN00611C-(cit45)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1039\/C7AN00486A","volume":"142","author":"Zhang","year":"2017","journal-title":"Analyst"},{"key":"C8AN00611C-(cit46)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/j.bios.2016.07.103","volume":"86","author":"Zhang","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"C8AN00611C-(cit47)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5483","DOI":"10.1038\/sj.onc.1205699","volume":"21","author":"JudithK","year":"2002","journal-title":"Oncogene"},{"key":"C8AN00611C-(cit48)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8556","DOI":"10.1021\/acs.analchem.6b01579","volume":"88","author":"Li","year":"2016","journal-title":"Anal. Chem."}],"container-title":["The Analyst"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2018\/AN\/C8AN00611C","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T06:32:33Z","timestamp":1782887553000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/an\/article\/143\/14\/3353-3359\/591512"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":48,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.1039\/c8an00611c","relation":{},"ISSN":["0003-2654","1364-5528"],"issn-type":[{"value":"0003-2654","type":"print"},{"value":"1364-5528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Supplementary Information","URL":"https:\/\/doi.org\/10.1039\/C8AN00611C","name":"related_data","group":{"name":"related_data","label":"RELATED DATA"}},{"value":"Hui Zhang (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-4922-3745","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Jiu-Ju Feng (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-7954-0573","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 2 April 2018; Accepted 7 June 2018;  Accepted Manuscript published 8 June 2018;  Advance Article published 12 June 2018;  Version of Record published 9 July 2018","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}