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Biomol. Chem."],"abstract":"<p>\n                    Various functional 3-acyl-1,5-benzodiazepines were synthesized\n                    <italic>via<\/italic>\n                    a catalyst-free four-component domino reaction. A total of 26 examples were examined by reacting inexpensive starting materials of\n                    <italic>N<\/italic>\n                    ,\n                    <italic>N<\/italic>\n                    -dimethylformamide dimethyl acetal, aromatic ketones, 1,2-phenylenediamine compounds and aldehyde derivatives in high yields.\n                  <\/p>","DOI":"10.1039\/c8ob02903b","type":"journal-article","created":{"date-parts":[[2019,1,3]],"date-time":"2019-01-03T22:04:17Z","timestamp":1546553057000},"page":"930-938","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["A catalyst-free four-component domino reaction for the synthesis of functionalized 3-acyl-1,5-benzodiazepines"],"prefix":"10.1039","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7564-9846","authenticated-orcid":false,"given":"Yue-Wei","family":"Sun","sequence":"first","affiliation":[{"name":"College of Chemistry & Material Science"},{"name":"Hebei Normal University"},{"name":"Shijiazhuang 050024"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue-Ming","family":"Bei","sequence":"additional","affiliation":[{"name":"College of Chemistry & Material Science"},{"name":"Hebei Normal University"},{"name":"Shijiazhuang 050024"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3666-8208","authenticated-orcid":false,"given":"Lan-Zhi","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Chemistry & Material Science"},{"name":"Hebei Normal University"},{"name":"Shijiazhuang 050024"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2019]]},"reference":[{"key":"C8OB02903B-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3443","DOI":"10.1002\/1521-3757(20010917)113:18<3443::AID-ANGE3443>3.0.CO;2-S","volume":"113","author":"Wess","year":"2001","journal-title":"Angew. 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