{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T20:26:14Z","timestamp":1791836774789,"version":"4.3.4"},"reference-count":46,"publisher":"Royal Society of Chemistry (RSC)","issue":"2","license":[{"start":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T00:00:00Z","timestamp":1605657600000},"content-version":"am","delay-in-days":322,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["21572177"],"award-info":[{"award-number":["21572177"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100009103","name":"Education Department of Shaanxi Province","doi-asserted-by":"crossref","award":["18JK0774"],"award-info":[{"award-number":["18JK0774"]}],"id":[{"id":"10.13039\/501100009103","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004194","name":"Northwest University","doi-asserted-by":"crossref","award":["2019253"],"award-info":[{"award-number":["2019253"]}],"id":[{"id":"10.13039\/501100004194","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004194","name":"Northwest University","doi-asserted-by":"crossref","award":["YZZ17169"],"award-info":[{"award-number":["YZZ17169"]}],"id":[{"id":"10.13039\/501100004194","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Analyst"],"abstract":"<p>A novel turn-on fluorescent probe with barbituric acid as a unique recognition group has been rationally designed and synthesized using a facile method for detecting hydrazine.<\/p>","DOI":"10.1039\/c9an02058f","type":"journal-article","created":{"date-parts":[[2019,11,17]],"date-time":"2019-11-17T22:03:34Z","timestamp":1574028214000},"page":"636-642","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Rational design of a novel turn-on fluorescent probe for the detection and bioimaging of hydrazine with barbituric acid as a recognition group"],"prefix":"10.1039","volume":"145","author":[{"given":"Junli","family":"Du","sequence":"first","affiliation":[{"name":"School of Pharmacy"},{"name":"Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University)"},{"name":"Ministry of Education"},{"name":"Biomedicine Key Laboratory of Shaanxi Province"},{"name":"Northwest University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolu","family":"Li","sequence":"additional","affiliation":[{"name":"School of Pharmacy"},{"name":"Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University)"},{"name":"Ministry of Education"},{"name":"Biomedicine Key Laboratory of Shaanxi Province"},{"name":"Northwest University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Songsong","family":"Ruan","sequence":"additional","affiliation":[{"name":"School of Pharmacy"},{"name":"Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University)"},{"name":"Ministry of Education"},{"name":"Biomedicine Key Laboratory of Shaanxi Province"},{"name":"Northwest University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingchun","family":"Li","sequence":"additional","affiliation":[{"name":"School of Pharmacy"},{"name":"Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University)"},{"name":"Ministry of Education"},{"name":"Biomedicine Key Laboratory of Shaanxi Province"},{"name":"Northwest University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Ren","sequence":"additional","affiliation":[{"name":"School of Pharmacy"},{"name":"Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University)"},{"name":"Ministry of Education"},{"name":"Biomedicine Key Laboratory of Shaanxi Province"},{"name":"Northwest University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanjun","family":"Cao","sequence":"additional","affiliation":[{"name":"School of Pharmacy"},{"name":"Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University)"},{"name":"Ministry of Education"},{"name":"Biomedicine Key Laboratory of Shaanxi Province"},{"name":"Northwest University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqing","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education"},{"name":"College of Chemistry & Materials Science"},{"name":"Northwest University"},{"name":"Xi'an"},{"name":"P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongmin","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Pharmacy"},{"name":"Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University)"},{"name":"Ministry of Education"},{"name":"Biomedicine Key Laboratory of Shaanxi Province"},{"name":"Northwest University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6235-7687","authenticated-orcid":false,"given":"Shaoping","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Pharmacy"},{"name":"Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University)"},{"name":"Ministry of Education"},{"name":"Biomedicine Key Laboratory of Shaanxi Province"},{"name":"Northwest University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4853-7961","authenticated-orcid":false,"given":"Jianli","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education"},{"name":"College of Chemistry & Materials Science"},{"name":"Northwest University"},{"name":"Xi'an"},{"name":"P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2020]]},"reference":[{"key":"C9AN02058F-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5425","DOI":"10.1021\/ja111160r","volume":"133","author":"Sanabria-Chinchilla","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"C9AN02058F-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"10336","DOI":"10.1002\/anie.201404734","volume":"53","author":"Serov","year":"2014","journal-title":"Angew. Chem., Int. Ed."},{"key":"C9AN02058F-(cit3)\/*[position()=1]","volume-title":"Ullmann's Encyclopedia of Industrial Chemistry","author":"Schirmann","year":"2002","unstructured":"J. P. Schirmann   and  P.Bourdauducq ,  Ullmann's Encyclopedia of Industrial Chemistry ,  Wiley-VCH ,  Weinheim ,  2002"},{"key":"C9AN02058F-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1021\/tx960189l","volume":"10","author":"Reilly","year":"1997","journal-title":"Chem. Res. Toxicol."},{"key":"C9AN02058F-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7204","DOI":"10.1016\/j.electacta.2010.07.053","volume":"55","author":"Wang","year":"2010","journal-title":"Electrochim. Acta"},{"key":"C9AN02058F-(cit6)\/*[position()=1]","volume-title":"Integrated Risk Information System (IRIS) on Hydrazine\/Hydrazine Sulfate","author":"U. S. E. P. A.","year":"1999","unstructured":"U. S. E. P. A.  ,  Integrated Risk Information System (IRIS) on Hydrazine\/Hydrazine Sulfate ,  National Center for Environmental Assessment, Office of Research and Development ,  Washington, D. C. ,  1999"},{"key":"C9AN02058F-(cit7)\/*[position()=1]","volume-title":"Hydrazine Hazard Summary-Created in April 1992; Revised in January 2000","author":"U. S. E. P. A.","year":"2008","unstructured":"U. S. E. P. A.  ,  Hydrazine Hazard Summary-Created in April 1992; Revised in January 2000 ,  Office of Research and Development ,  Washington, D. C. ,  2008"},{"key":"C9AN02058F-(cit8)\/*[position()=1]","first-page":"1285","volume":"74","author":"Zelnick","year":"2003","journal-title":"Aviat., Space Environ. Med."},{"key":"C9AN02058F-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.jpba.2008.11.009","volume":"49","author":"Sun","year":"2009","journal-title":"J. Pharm. Biomed. Anal."},{"key":"C9AN02058F-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1039\/B711215G","author":"Umar","year":"2008","journal-title":"Chem. Commun."},{"key":"C9AN02058F-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3350","DOI":"10.1021\/ac9604696","volume":"68","author":"Liu","year":"1996","journal-title":"Anal. Chem."},{"key":"C9AN02058F-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1016\/j.electacta.2010.11.083","volume":"56","author":"Benvidi","year":"2011","journal-title":"Electrochim. Acta"},{"key":"C9AN02058F-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/j.snb.2015.07.003","volume":"221","author":"Cheng","year":"2015","journal-title":"Sens. Actuators, B"},{"key":"C9AN02058F-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0039-9140(02)00362-4","volume":"58","author":"Safavi","year":"2002","journal-title":"Talanta"},{"key":"C9AN02058F-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0003-2670(99)00890-9","volume":"409","author":"He","year":"2000","journal-title":"Anal. Chim. Acta"},{"key":"C9AN02058F-(cit16a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.dyepig.2019.01.028","volume":"164","author":"Feng","year":"2019","journal-title":"Dyes Pigm."},{"key":"C9AN02058F-(cit16b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/j.snb.2018.02.070","volume":"262","author":"Hong","year":"2018","journal-title":"Sens. Actuators, B"},{"key":"C9AN02058F-(cit16c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.aca.2018.04.048","volume":"1029","author":"Feng","year":"2018","journal-title":"Anal. Chim. Acta"},{"key":"C9AN02058F-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.aca.2015.08.041","volume":"893","author":"Nandi","year":"2015","journal-title":"Anal. Chim. Acta"},{"key":"C9AN02058F-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"17924","DOI":"10.1039\/c3ra42717j","volume":"3","author":"Lin","year":"2013","journal-title":"RSC Adv."},{"key":"C9AN02058F-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"18872","DOI":"10.1039\/c3ra42771d","volume":"3","author":"Goswami","year":"2013","journal-title":"RSC Adv."},{"key":"C9AN02058F-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5260","DOI":"10.1021\/ol202136q","volume":"13","author":"Choi","year":"2011","journal-title":"Org. Lett."},{"key":"C9AN02058F-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"14678","DOI":"10.1039\/C5RA26683A","volume":"6","author":"Tse","year":"2016","journal-title":"RSC Adv."},{"key":"C9AN02058F-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1016\/j.tetlet.2017.05.003","volume":"58","author":"Jiang","year":"2017","journal-title":"Tetrahedron Lett."},{"key":"C9AN02058F-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.cclet.2016.01.024","volume":"27","author":"Tang","year":"2016","journal-title":"Chin. Chem. Lett."},{"key":"C9AN02058F-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5412","DOI":"10.1021\/ol4026759","volume":"15","author":"Goswami","year":"2013","journal-title":"Org. Lett."},{"key":"C9AN02058F-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5344","DOI":"10.1039\/C5OB00209E","volume":"13","author":"Zhou","year":"2015","journal-title":"Org. Biomol. Chem."},{"key":"C9AN02058F-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4022","DOI":"10.1021\/ol401838p","volume":"15","author":"Hu","year":"2013","journal-title":"Org. Lett."},{"key":"C9AN02058F-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"9918","DOI":"10.1021\/acs.analchem.7b02149","volume":"89","author":"Lu","year":"2017","journal-title":"Anal. Chem."},{"key":"C9AN02058F-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8117","DOI":"10.1039\/c2cc34168a","volume":"48","author":"Fan","year":"2012","journal-title":"Chem. Commun."},{"key":"C9AN02058F-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1016\/j.dyepig.2013.08.008","volume":"99","author":"Tan","year":"2013","journal-title":"Dyes Pigm."},{"key":"C9AN02058F-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.snb.2014.11.057","volume":"208","author":"Sun","year":"2015","journal-title":"Sens. Actuators, B"},{"key":"C9AN02058F-(cit31a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2653","DOI":"10.1039\/c3ay40148k","volume":"5","author":"Li","year":"2013","journal-title":"Anal. Methods"},{"key":"C9AN02058F-(cit31b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5832","DOI":"10.1039\/C6AY01367H","volume":"8","author":"Zhai","year":"2016","journal-title":"Anal. Methods"},{"key":"C9AN02058F-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.snb.2014.05.010","volume":"202","author":"Liu","year":"2014","journal-title":"Sens. Actuators, B"},{"key":"C9AN02058F-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"41807","DOI":"10.1039\/C4RA08101C","volume":"4","author":"Xiao","year":"2014","journal-title":"RSC Adv."},{"key":"C9AN02058F-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.aca.2008.07.016","volume":"625","author":"Chen","year":"2008","journal-title":"Anal. Chim. Acta"},{"key":"C9AN02058F-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1039\/C3CC48304E","volume":"50","author":"Cui","year":"2014","journal-title":"Chem. Commun."},{"key":"C9AN02058F-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4611","DOI":"10.1021\/ac5007552","volume":"86","author":"Cui","year":"2014","journal-title":"Anal. Chem."},{"key":"C9AN02058F-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5412","DOI":"10.1021\/ol4026759","volume":"15","author":"Goswami","year":"2013","journal-title":"Org. Lett."},{"key":"C9AN02058F-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.bios.2014.02.059","volume":"58","author":"Qian","year":"2014","journal-title":"Biosens. Bioelectron."},{"key":"C9AN02058F-(cit39)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.snb.2015.03.088","volume":"216","author":"Jin","year":"2015","journal-title":"Sens. Actuators, B"},{"key":"C9AN02058F-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6488","DOI":"10.1021\/ol202777h","volume":"13","author":"Cui","year":"2011","journal-title":"Org. Lett."},{"key":"C9AN02058F-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1016\/j.tet.2008.12.078","volume":"65","author":"Herbivo","year":"2009","journal-title":"Tetrahedron"},{"key":"C9AN02058F-(cit42)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.snb.2017.11.095","volume":"258","author":"Sun","year":"2018","journal-title":"Sens. Actuators, B"},{"key":"C9AN02058F-(cit43)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0166-1280(98)00553-3","volume":"464","author":"Tomasi","year":"1999","journal-title":"J. Mol. Struct.: THEOCHEM"}],"container-title":["The Analyst"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2020\/AN\/C9AN02058F","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T02:51:30Z","timestamp":1782874290000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/an\/article\/145\/2\/636-642\/631933"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":46,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,1,20]]}},"URL":"https:\/\/doi.org\/10.1039\/c9an02058f","relation":{},"ISSN":["0003-2654","1364-5528"],"issn-type":[{"value":"0003-2654","type":"print"},{"value":"1364-5528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Supplementary Information","URL":"https:\/\/doi.org\/10.1039\/C9AN02058F","name":"related_data","group":{"name":"related_data","label":"RELATED DATA"}},{"value":"Shaoping Wu (ORCID)","URL":"http:\/\/orcid.org\/0000-0001-6235-7687","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Jianli Li (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-4853-7961","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 15 October 2019; Accepted 14 November 2019;  Accepted Manuscript published 18 November 2019;  Advance Article published 2 December 2019;  Version of Record published 20 January 2020","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}