{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T18:13:30Z","timestamp":1789841610684,"version":"4.0.1"},"reference-count":42,"publisher":"Royal Society of Chemistry (RSC)","issue":"3","license":[{"start":{"date-parts":[[2020,11,15]],"date-time":"2020-11-15T00:00:00Z","timestamp":1605398400000},"content-version":"am","delay-in-days":319,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81570682"],"award-info":[{"award-number":["81570682"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["811774125"],"award-info":[{"award-number":["811774125"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Biomater. Sci."],"abstract":"<p>A large proportion of benign prostatic hyperplasia (BPH) patients suffer from lower urinary tract symptoms after surgery due to the presence of prostatic urothelium wounds.<\/p>","DOI":"10.1039\/c9bm01512d","type":"journal-article","created":{"date-parts":[[2019,11,15]],"date-time":"2019-11-15T09:24:49Z","timestamp":1573809889000},"page":"912-925","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Rebamipide-loaded chitosan nanoparticles accelerate prostatic wound healing by inhibiting M1 macrophage-mediated inflammation\n                    <i>via<\/i>\n                    the NF-\u03baB signaling pathway"],"prefix":"10.1039","volume":"8","author":[{"given":"Menghao","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Urology"},{"name":"Shanghai General Hospital"},{"name":"Shanghai Jiao Tong University"},{"name":"School of Medicine"},{"name":"Shanghai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Urology"},{"name":"Shanghai General Hospital"},{"name":"Shanghai Jiao Tong University"},{"name":"School of Medicine"},{"name":"Shanghai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Urology"},{"name":"Shanghai General Hospital"},{"name":"Shanghai Jiao Tong University"},{"name":"School of Medicine"},{"name":"Shanghai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Urology"},{"name":"Shanghai General Hospital Affiliated to Nanjing Medical University"},{"name":"Shanghai 200080"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenyi","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Urology"},{"name":"Shanghai General Hospital"},{"name":"Shanghai Jiao Tong University"},{"name":"School of Medicine"},{"name":"Shanghai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhilu","family":"Xu","sequence":"additional","affiliation":[{"name":"College of Pharmacy"},{"name":"Weifang Medical University"},{"name":"Weifang 261053"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoming","family":"Cui","sequence":"additional","affiliation":[{"name":"College of Pharmacy"},{"name":"Weifang Medical University"},{"name":"Weifang 261053"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wentong","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pathology"},{"name":"Weifang Medical University"},{"name":"Weifang 261053"},{"name":"China"},{"name":"Shandong Engineering Research Center for Smart Materials and Regenerative Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifeng","family":"Jing","sequence":"additional","affiliation":[{"name":"Department of Urology"},{"name":"Shanghai General Hospital"},{"name":"Shanghai Jiao Tong University"},{"name":"School of Medicine"},{"name":"Shanghai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bangmin","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Urology"},{"name":"Shanghai General Hospital"},{"name":"Shanghai Jiao Tong University"},{"name":"School of Medicine"},{"name":"Shanghai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weifen","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Pharmacy"},{"name":"Weifang Medical University"},{"name":"Weifang 261053"},{"name":"China"},{"name":"Shandong Engineering Research Center for Smart Materials and Regenerative Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7664-1707","authenticated-orcid":false,"given":"Shujie","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Urology"},{"name":"Shanghai General Hospital"},{"name":"Shanghai Jiao Tong University"},{"name":"School of Medicine"},{"name":"Shanghai"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2020]]},"reference":[{"issue":"Suppl. 1","key":"C9BM01512D-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.1007\/BF00942041","volume":"25","author":"Sulser","year":"1997","journal-title":"Urol. Res."},{"issue":"2","key":"C9BM01512D-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s00345-010-0605-8","volume":"29","author":"Martin","year":"2011","journal-title":"World J. Urol."},{"issue":"10","key":"C9BM01512D-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1007\/s00345-017-2023-7","volume":"35","author":"Al-Rawashdah","year":"2017","journal-title":"World J. Urol."},{"issue":"5","key":"C9BM01512D-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/j.eururo.2005.12.042","volume":"50","author":"Rassweiler","year":"2006","journal-title":"Eur. Urol."},{"issue":"2","key":"C9BM01512D-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.eururo.2007.05.019","volume":"53","author":"Xia","year":"2008","journal-title":"Eur. Urol."},{"issue":"1","key":"C9BM01512D-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/S0090-4295(98)00524-X","volume":"53","author":"Uchida","year":"1999","journal-title":"Urology"},{"issue":"7193","key":"C9BM01512D-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1038\/nature07039","volume":"453","author":"Gurtner","year":"2008","journal-title":"Nature"},{"issue":"20","key":"C9BM01512D-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3861","DOI":"10.1007\/s00018-016-2268-0","volume":"73","author":"Landen","year":"2016","journal-title":"Cell. Mol. Life Sci."},{"issue":"7","key":"C9BM01512D-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1002\/pros.23301","volume":"77","author":"Wang","year":"2017","journal-title":"Prostate"},{"issue":"3","key":"C9BM01512D-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"e12415","DOI":"10.1111\/cpr.12415","volume":"51","author":"Zhao","year":"2018","journal-title":"Cell Proliferation"},{"key":"C9BM01512D-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.taap.2019.01.022","volume":"366","author":"Deng","year":"2019","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"9 Suppl.","key":"C9BM01512D-(cit12)\/*[position()=1]","first-page":"5s","volume":"43","author":"Arakawa","year":"1998","journal-title":"Dig. Dis. Sci."},{"issue":"4","key":"C9BM01512D-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1111\/vop.12510","volume":"21","author":"Tajima","year":"2018","journal-title":"Vet. Ophthalmol."},{"issue":"1","key":"C9BM01512D-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/s10753-015-0271-5","volume":"39","author":"Kim","year":"2016","journal-title":"Inflammation"},{"issue":"4","key":"C9BM01512D-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/j.juro.2013.11.026","volume":"191","author":"Funahashi","year":"2014","journal-title":"J. Urol."},{"key":"C9BM01512D-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.exer.2016.07.003","volume":"151","author":"Nagai","year":"2016","journal-title":"Exp. Eye Res."},{"issue":"6","key":"C9BM01512D-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1016\/j.juro.2014.06.081","volume":"192","author":"Funahashi","year":"2014","journal-title":"J. Urol."},{"issue":"2","key":"C9BM01512D-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1124\/jpet.113.208991","volume":"348","author":"Satoh","year":"2014","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"33","key":"C9BM01512D-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"3802","DOI":"10.3748\/wjg.v17.i33.3802","volume":"17","author":"Takagi","year":"2011","journal-title":"World J. Gastroenterol."},{"issue":"3","key":"C9BM01512D-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.rmed.2005.06.006","volume":"100","author":"Lee","year":"2006","journal-title":"Respir. Med."},{"issue":"1\u20133","key":"C9BM01512D-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.ejphar.2013.10.035","volume":"720","author":"Wood 3rd","year":"2013","journal-title":"Eur. J. Pharmacol."},{"issue":"7","key":"C9BM01512D-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1007\/s00210-017-1370-7","volume":"390","author":"Gendy","year":"2017","journal-title":"Naunyn-Schmiedeberg's Arch. Pharmacol."},{"issue":"3","key":"C9BM01512D-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.jconrel.2008.10.002","volume":"133","author":"Li","year":"2009","journal-title":"J. Controlled Release"},{"key":"C9BM01512D-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.colsurfb.2018.04.047","volume":"167","author":"Takeuchi","year":"2018","journal-title":"Colloids Surf., B"},{"issue":"1","key":"C9BM01512D-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1208\/s12249-018-1225-7","volume":"20","author":"Narala","year":"2019","journal-title":"AAPS PharmSciTech"},{"issue":"Pt B","key":"C9BM01512D-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.ejpb.2015.08.004","volume":"97","author":"Patrulea","year":"2015","journal-title":"Eur. J. Pharm. Biopharm."},{"issue":"3","key":"C9BM01512D-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1089\/jop.2000.16.261","volume":"16","author":"Felt","year":"2000","journal-title":"J. Ocul. Pharmacol. Ther."},{"issue":"1","key":"C9BM01512D-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/jbm.b.30853","volume":"84","author":"Yang","year":"2008","journal-title":"J. Biomed. Mater. Res., Part B"},{"key":"C9BM01512D-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/j.ijbiomac.2016.02.015","volume":"86","author":"Tu","year":"2016","journal-title":"Int. J. Biol. Macromol."},{"key":"C9BM01512D-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.actbio.2016.07.025","volume":"43","author":"Denora","year":"2016","journal-title":"Acta Biomater."},{"key":"C9BM01512D-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8239","DOI":"10.2147\/IJN.S147028","volume":"12","author":"Liu","year":"2017","journal-title":"Int. J. Nanomed."},{"issue":"1","key":"C9BM01512D-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.ab.2010.03.031","volume":"402","author":"Chutipongtanate","year":"2010","journal-title":"Anal. Biochem."},{"issue":"1","key":"C9BM01512D-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/10837450.2017.1312441","volume":"23","author":"Oliveira","year":"2018","journal-title":"Pharm. Dev. Technol."},{"issue":"1","key":"C9BM01512D-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.reactfunctpolym.2006.09.001","volume":"67","author":"Prabaharan","year":"2007","journal-title":"React. Funct. Polym."},{"issue":"5","key":"C9BM01512D-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"831","DOI":"10.4103\/1008-682X.146972","volume":"17","author":"Cao","year":"2015","journal-title":"Asian J. Androl."},{"key":"C9BM01512D-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1146\/annurev-physiol-022516-034339","volume":"79","author":"Murray","year":"2017","journal-title":"Annu. Rev. Physiol."},{"issue":"3","key":"C9BM01512D-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1586\/egh.10.25","volume":"4","author":"Naito","year":"2010","journal-title":"Expert Rev. Gastroenterol. Hepatol."},{"issue":"8","key":"C9BM01512D-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1081\/DDC-200034577","volume":"30","author":"Shin","year":"2004","journal-title":"Drug Dev. Ind. Pharm."},{"issue":"4","key":"C9BM01512D-(cit39)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1007\/s12272-014-0399-0","volume":"38","author":"Pradhan","year":"2015","journal-title":"Arch. Pharmacal Res."},{"issue":"5","key":"C9BM01512D-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1248\/bpb.26.743","volume":"26","author":"Bogataj","year":"2003","journal-title":"Biol. Pharm. Bull."},{"issue":"5","key":"C9BM01512D-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.devcel.2013.07.017","volume":"26","author":"Gandhi","year":"2013","journal-title":"Dev. Cell"},{"key":"C9BM01512D-(cit42)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.actbio.2019.02.006","author":"Yang","year":"2019","journal-title":"Acta Biomater."}],"container-title":["Biomaterials Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2020\/BM\/C9BM01512D","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T03:11:28Z","timestamp":1782875488000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/bm\/article\/8\/3\/912-925\/633371"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,2,4]]}},"URL":"https:\/\/doi.org\/10.1039\/c9bm01512d","relation":{},"ISSN":["2047-4830","2047-4849"],"issn-type":[{"value":"2047-4830","type":"print"},{"value":"2047-4849","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Supplementary Information","URL":"https:\/\/doi.org\/10.1039\/C9BM01512D","name":"related_data","group":{"name":"related_data","label":"RELATED DATA"}},{"value":"Shujie Xia (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-7664-1707","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 19 September 2019; Accepted 7 November 2019; Accepted Manuscript published 15 November 2019; Advance Article published 12 December 2019; Version of Record published 4 February 2020","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}