{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T04:51:37Z","timestamp":1790484697660,"version":"4.1.0"},"reference-count":44,"publisher":"Royal Society of Chemistry (RSC)","issue":"11","license":[{"start":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T00:00:00Z","timestamp":1619740800000},"content-version":"am","delay-in-days":485,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"crossref","award":["2016YFB1101501"],"award-info":[{"award-number":["2016YFB1101501"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Biomater. Sci."],"abstract":"<p>Sustainable release of vancomycin from micro-arc oxidised 3D-printed porous Ti6A14V for treating MRSA bone infection and enhancing osteogenesis.<\/p>","DOI":"10.1039\/c9bm01968e","type":"journal-article","created":{"date-parts":[[2020,4,30]],"date-time":"2020-04-30T04:25:01Z","timestamp":1588220701000},"page":"3106-3115","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Sustainable release of vancomycin from micro-arc oxidised 3D-printed porous Ti6Al4V for treating methicillin-resistant\n                    <i>Staphylococcus aureus<\/i>\n                    bone infection and enhancing osteogenesis in a rabbit tibia osteomyelitis model"],"prefix":"10.1039","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7729-8023","authenticated-orcid":false,"given":"Teng","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Orthopedics"},{"name":"Peking University Third Hospital"},{"name":"Beijing 100191"},{"name":"People's Republic of China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingguang","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Orthopedics"},{"name":"Peking University Third Hospital"},{"name":"Beijing 100191"},{"name":"People's Republic of China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Orthopedics"},{"name":"Peking University Third Hospital"},{"name":"Beijing 100191"},{"name":"People's Republic of China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhao","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Engineering"},{"name":"College of Engineering"},{"name":"Peking University"},{"name":"Beijing 100871"},{"name":"People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daoyang","family":"Fan","sequence":"additional","affiliation":[{"name":"Department of Orthopedics"},{"name":"Peking University Third Hospital"},{"name":"Beijing 100191"},{"name":"People's Republic of China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinhong","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Orthopedics"},{"name":"Peking University Third Hospital"},{"name":"Beijing 100191"},{"name":"People's Republic of China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zehao","family":"Jing","sequence":"additional","affiliation":[{"name":"Department of Orthopedics"},{"name":"Peking University Third Hospital"},{"name":"Beijing 100191"},{"name":"People's Republic of China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Orthopedics"},{"name":"Peking University Third Hospital"},{"name":"Beijing 100191"},{"name":"People's Republic of China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5823-8108","authenticated-orcid":false,"given":"Yan","family":"Cheng","sequence":"additional","affiliation":[{"name":"Engineering Research Center of Bone and Joint Precision Medicine"},{"name":"Ministry of Education"},{"name":"Beijing 100191"},{"name":"People's Republic of China"},{"name":"Department of Materials Science and Engineering"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoguang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Orthopedics"},{"name":"Peking University Third Hospital"},{"name":"Beijing 100191"},{"name":"People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weishi","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopedics"},{"name":"Peking University Third Hospital"},{"name":"Beijing 100191"},{"name":"People's Republic of China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunli","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Orthopedics"},{"name":"Peking University Third Hospital"},{"name":"Beijing 100191"},{"name":"People's Republic of China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Orthopedics"},{"name":"Peking University Third Hospital"},{"name":"Beijing 100191"},{"name":"People's Republic of China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanfang","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Orthopedics"},{"name":"Peking University Third Hospital"},{"name":"Beijing 100191"},{"name":"People's Republic of China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufeng","family":"Zheng","sequence":"additional","affiliation":[{"name":"Engineering Research Center of Bone and Joint Precision Medicine"},{"name":"Ministry of Education"},{"name":"Beijing 100191"},{"name":"People's Republic of China"},{"name":"Department of Materials Science and Engineering"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongjun","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Orthopedics"},{"name":"Peking University Third Hospital"},{"name":"Beijing 100191"},{"name":"People's Republic of China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2020]]},"reference":[{"key":"C9BM01968E-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.idc.2018.06.005","volume":"32","author":"Beam","year":"2018","journal-title":"Infect. Dis. Clin. North Am."},{"key":"C9BM01968E-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"S17","DOI":"10.5435\/JAAOS-D-16-00639","volume":"25","author":"Osmon","year":"2017","journal-title":"J. Am. Acad. Orthop. Surg."},{"key":"C9BM01968E-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"147","DOI":"10.3109\/17453674.2014.966290","volume":"86","author":"Gbejuade","year":"2015","journal-title":"Acta Orthop."},{"key":"C9BM01968E-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"25830","DOI":"10.1021\/acsami.7b06757","volume":"9","author":"Zhou","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"C9BM01968E-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.actbio.2018.08.037","volume":"79","author":"Yan","year":"2018","journal-title":"Acta Biomater."},{"key":"C9BM01968E-(cit6)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/ijos.2014.65","volume":"7","author":"Wu","year":"2015","journal-title":"Int. J. Oral Sci."},{"key":"C9BM01968E-(cit7)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"i37","DOI":"10.1093\/jac\/dku254","volume":"69","author":"Jacqueline","year":"2014","journal-title":"J. Antimicrob. Chemother."},{"key":"C9BM01968E-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4441","DOI":"10.1021\/acsnano.6b00087","volume":"10","author":"Min","year":"2016","journal-title":"ACS Nano"},{"key":"C9BM01968E-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"153","DOI":"10.5435\/JAAOS-22-03-153","volume":"22","author":"Kuzyk","year":"2014","journal-title":"J. Am. Acad. Orthop. Surg."},{"key":"C9BM01968E-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/S1473-3099(18)30345-1","volume":"18","author":"Lenguerrand","year":"2018","journal-title":"Lancet Infect. Dis."},{"key":"C9BM01968E-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1302\/0301-620X.97B2.34554","volume":"97","author":"Wafa","year":"2015","journal-title":"Bone Joint J."},{"key":"C9BM01968E-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"e009495","DOI":"10.1136\/bmjopen-2015-009495","volume":"5","author":"Moore","year":"2015","journal-title":"BMJ Open"},{"key":"C9BM01968E-(cit13)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1002\/jor.23776","volume":"36","author":"Bue","year":"2018","journal-title":"J. Orthop. Res."},{"key":"C9BM01968E-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1016\/j.injury.2017.04.040","volume":"48","author":"Working","year":"2017","journal-title":"Injury"},{"key":"C9BM01968E-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"232","DOI":"10.22203\/eCM.v030a16","volume":"30","author":"Inzana","year":"2015","journal-title":"Eur. Cell Mater."},{"key":"C9BM01968E-(cit16)\/*[position()=1]","first-page":"30035","volume":"S1742\u20137061","author":"Caplin","year":"2019","journal-title":"Acta Biomater."},{"key":"C9BM01968E-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"e0118696","DOI":"10.1371\/journal.pone.0118696","volume":"10","author":"Brooks","year":"2015","journal-title":"PLoS One"},{"key":"C9BM01968E-(cit18)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5128","DOI":"10.1021\/acsami.6b14912","volume":"9","author":"Besheli","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"C9BM01968E-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"E50","DOI":"10.1097\/BRS.0000000000001179","volume":"41","author":"Xu","year":"2016","journal-title":"Spine"},{"key":"C9BM01968E-(cit20)\/*[position()=1]","first-page":"30477","volume":"S1742\u20137061","author":"Bassous","year":"2019","journal-title":"Acta Biomater."},{"key":"C9BM01968E-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1078\/0171-9335-00104","volume":"79","author":"Fowler","year":"2000","journal-title":"Eur. J. Cell Biol."},{"key":"C9BM01968E-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/s40843-017-9208-x","volume":"61","author":"Zhang","year":"2018","journal-title":"Sci. China Mater."},{"key":"C9BM01968E-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1126\/science.1147241","volume":"318","author":"Lee","year":"2007","journal-title":"Science"},{"key":"C9BM01968E-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"7523","DOI":"10.1021\/acsami.7b19865","volume":"10","author":"Ryu","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"C9BM01968E-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1016\/j.nano.2017.11.119","volume":"14","author":"Wang","year":"2018","journal-title":"Nanomedicine"},{"key":"C9BM01968E-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/j.msec.2017.03.071","volume":"76","author":"Bai","year":"2017","journal-title":"Mater. Sci. Eng., C"},{"key":"C9BM01968E-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"17964","DOI":"10.1021\/acsami.6b05893","volume":"8","author":"Xiu","year":"2016","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"C9BM01968E-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1111\/jop.12464","volume":"46","author":"K\u00e4mmerer","year":"2017","journal-title":"J. Oral Pathol. Med."},{"key":"C9BM01968E-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/1749-799X-8-38","volume":"8","author":"Odekerken","year":"2013","journal-title":"J. Orthop. Surg. Res."},{"key":"C9BM01968E-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/1749-799X-8-38","volume":"8","author":"Odekerken","year":"2013","journal-title":"J. Orthop. Surg. Res."},{"key":"C9BM01968E-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.compscitech.2017.04.037","volume":"147","author":"Zhao","year":"2017","journal-title":"Compos. Sci. Technol."},{"key":"C9BM01968E-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"E4960","DOI":"10.1073\/pnas.1801013115","volume":"115","author":"Johnson","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"C9BM01968E-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1128\/JCM.03683-14","volume":"53","author":"Portillo","year":"2015","journal-title":"J. Clin. Microbiol."},{"key":"C9BM01968E-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"28495","DOI":"10.1021\/acsami.6b10473","volume":"8","author":"Jia","year":"2016","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"C9BM01968E-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1039\/C8BM00298C","volume":"6","author":"Li","year":"2018","journal-title":"Biomater. Sci."},{"key":"C9BM01968E-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"17935","DOI":"10.1021\/acsami.5b04597","volume":"7","author":"Huang","year":"2015","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"C9BM01968E-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"13075","DOI":"10.1073\/pnas.0805862105","volume":"105","author":"Schuksz","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"C9BM01968E-(cit38)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.ijpharm.2016.11.062","volume":"517","author":"Ionita","year":"2017","journal-title":"Int. J. Pharm."},{"key":"C9BM01968E-(cit39)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.surfcoat.2018.11.037","volume":"358","author":"Vidal","year":"2019","journal-title":"Surf. Coat. Technol."},{"key":"C9BM01968E-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.biomaterials.2014.12.048","volume":"45","author":"Lu","year":"2015","journal-title":"Biomaterials"},{"key":"C9BM01968E-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"87","DOI":"10.4103\/0971-5916.178615","volume":"143","author":"Kishor","year":"2016","journal-title":"Indian J. Med. Res."},{"key":"C9BM01968E-(cit42)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1002\/ptr.5755","volume":"31","author":"Shou","year":"2017","journal-title":"Phytother. Res."},{"key":"C9BM01968E-(cit43)\/*[position()=1]","first-page":"4995","volume":"14","author":"Zhang","year":"2017","journal-title":"Exp. Ther. Med."},{"key":"C9BM01968E-(cit44)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"d126","DOI":"10.2741\/A178","volume":"2","author":"Johansson","year":"1997","journal-title":"Front. Biosci."}],"container-title":["Biomaterials Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2020\/BM\/C9BM01968E","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T18:37:11Z","timestamp":1783449431000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/bm\/article\/8\/11\/3106-3115\/633470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":44,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,6,2]]}},"URL":"https:\/\/doi.org\/10.1039\/c9bm01968e","relation":{},"ISSN":["2047-4830","2047-4849"],"issn-type":[{"value":"2047-4830","type":"print"},{"value":"2047-4849","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Teng Zhang (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-7729-8023","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Yan Cheng (ORCID)","URL":"http:\/\/orcid.org\/0000-0001-5823-8108","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Yufeng Zheng (ResearcherID)","URL":"http:\/\/www.researcherid.com\/rid\/A-4146-2010","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 8 December 2019; Accepted 31 March 2020; Advance Article published 30 April 2020; Version of Record published 2 June 2020","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}