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Med."},{"key":"C9DT04594E-(cit30e)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1126\/science.1219855","volume":"337","author":"Youle","year":"2012","journal-title":"Science"},{"key":"C9DT04594E-(cit30f)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1039\/C8MT00125A","volume":"10","author":"Qin","year":"2018","journal-title":"Metallomics"},{"key":"C9DT04594E-(cit30g)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/nature03097","volume":"432","author":"Kastan","year":"2004","journal-title":"Nature"},{"key":"C9DT04594E-(cit30h)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.ejmech.2018.09.008","volume":"158","author":"Qin","year":"2018","journal-title":"Eur. J. Med. Chem."},{"key":"C9DT04594E-(cit30i)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5352","DOI":"10.1039\/C9DT00866G","volume":"48","author":"Meng","year":"2019","journal-title":"Dalton Trans."},{"key":"C9DT04594E-(cit30j)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1039\/C9MT00037B","volume":"11","author":"Qin","year":"2019","journal-title":"Metallomics"},{"key":"C9DT04594E-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/jat.727","volume":"21","author":"Diehl","year":"2001","journal-title":"J. Appl. Toxicol."},{"key":"C9DT04594E-(cit32a)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"12487","DOI":"10.1002\/chem.201601542","volume":"22","author":"Gothe","year":"2016","journal-title":"Chem. \u2013\nEur. J."},{"key":"C9DT04594E-(cit32b)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"6350","DOI":"10.1039\/c2dt12460b","volume":"41","author":"Patra","year":"2012","journal-title":"Dalton Trans."},{"key":"C9DT04594E-(cit32c)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"5931","DOI":"10.1021\/cr0101510","volume":"104","author":"van Staveren","year":"2004","journal-title":"Chem. Rev."},{"key":"C9DT04594E-(cit32d)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1021\/jm5012484","volume":"58","author":"Chen","year":"2015","journal-title":"J. Med. Chem."},{"key":"C9DT04594E-(cit32e)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.ejmech.2018.10.051","volume":"161","author":"Qin","year":"2019","journal-title":"Eur. J. Med. 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