{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T07:06:52Z","timestamp":1782889612241,"version":"3.54.5"},"reference-count":48,"publisher":"Royal Society of Chemistry (RSC)","issue":"10","license":[{"start":{"date-parts":[[2020,8,23]],"date-time":"2020-08-23T00:00:00Z","timestamp":1598140800000},"content-version":"am","delay-in-days":600,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["31671823"],"award-info":[{"award-number":["31671823"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["31871752"],"award-info":[{"award-number":["31871752"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"crossref","award":["GK201803074"],"award-info":[{"award-number":["GK201803074"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004303","name":"Shaanxi Normal University","doi-asserted-by":"crossref","award":["GK201801002"],"award-info":[{"award-number":["GK201801002"]}],"id":[{"id":"10.13039\/501100004303","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<p>This study assesses the possible effects of dietary okra seed oil (OSO) consumption on attenuation of alcohol-induced liver damage and gut microbiota dysbiosis, and associated mechanisms in mice.<\/p>","DOI":"10.1039\/c9fo00189a","type":"journal-article","created":{"date-parts":[[2019,8,23]],"date-time":"2019-08-23T06:39:35Z","timestamp":1566542375000},"page":"6385-6398","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Supplementation of okra seed oil ameliorates ethanol-induced liver injury and modulates gut microbiota dysbiosis in mice"],"prefix":"10.1039","volume":"10","author":[{"given":"Jin","family":"Zhang","sequence":"first","affiliation":[{"name":"Key Laboratory of Ministry of Education for Medicinal Resource and Natural Pharmaceutical Chemistry"},{"name":"College of Life Sciences"},{"name":"Shaanxi Normal University"},{"name":"Xi'an 710062"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5792-4819","authenticated-orcid":false,"given":"Yalong","family":"Lu","sequence":"additional","affiliation":[{"name":"Shaanxi Engineering Laboratory for Food Green Processing and Safety Control"},{"name":"College of Food Engineering and Nutritional Science"},{"name":"Shaanxi Normal University"},{"name":"Xi'an 710062"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8039-0525","authenticated-orcid":false,"given":"Xingbin","family":"Yang","sequence":"additional","affiliation":[{"name":"Shaanxi Engineering Laboratory for Food Green Processing and Safety Control"},{"name":"College of Food Engineering and Nutritional Science"},{"name":"Shaanxi Normal University"},{"name":"Xi'an 710062"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zhao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Ministry of Education for Medicinal Resource and Natural Pharmaceutical Chemistry"},{"name":"College of Life Sciences"},{"name":"Shaanxi Normal University"},{"name":"Xi'an 710062"},{"name":"China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2019]]},"reference":[{"issue":"1","key":"C9FO00189A-(cit1)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/biom6010001","volume":"6","author":"Irina","year":"2016","journal-title":"Biomolecules"},{"issue":"1","key":"C9FO00189A-(cit2)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1186\/s40168-017-0359-2","volume":"5","author":"Dubinkina","year":"2017","journal-title":"Microbiome"},{"issue":"6","key":"C9FO00189A-(cit3)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1016\/S0016-5085(00)70386-6","volume":"118","author":"Dimarino","year":"2000","journal-title":"Gastroenterology"},{"issue":"6","key":"C9FO00189A-(cit4)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1021\/jf60202a041","volume":"23","author":"Karakoltsidis","year":"1975","journal-title":"J. Agric. Food Chem."},{"issue":"1","key":"C9FO00189A-(cit5)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1053\/j.gastro.2014.11.023","volume":"148","author":"Tilg","year":"2015","journal-title":"Gastroenterology"},{"issue":"2","key":"C9FO00189A-(cit6)\/*[position()=1]","first-page":"638","volume":"299","author":"Nanji","year":"2001","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"93","key":"C9FO00189A-(cit7)\/*[position()=1]","first-page":"568","volume":"42","author":"You","year":"2010","journal-title":"Hepatology"},{"issue":"38","key":"C9FO00189A-(cit8)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"35931","DOI":"10.1074\/jbc.M306238200","volume":"278","author":"Anjali","year":"2003","journal-title":"J. Biol. Chem."},{"issue":"1","key":"C9FO00189A-(cit9)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00394-017-1445-8","volume":"57","author":"Rowland","year":"2018","journal-title":"Eur. J. Nutr."},{"issue":"3","key":"C9FO00189A-(cit10)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1093\/jn\/131.3.828","volume":"131","author":"Wolk","year":"2001","journal-title":"J. Nutr."},{"key":"C9FO00189A-(cit11)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/10408398.2018.1481821","volume":"31","author":"Coelho","year":"2018","journal-title":"Crit. Rev. Food Sci. Nutr."},{"issue":"3","key":"C9FO00189A-(cit12)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1002\/hep.27489","volume":"61","author":"Chen","year":"2015","journal-title":"Hepatology"},{"issue":"9","key":"C9FO00189A-(cit13)\/*[position()=1]","first-page":"966","volume":"302","author":"Mutlu","year":"2012","journal-title":"Am. J. Physiol.: Gastrointest. Liver Physiol."},{"issue":"4","key":"C9FO00189A-(cit14)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/j.ajpath.2015.11.017","volume":"186","author":"Kirpich","year":"2016","journal-title":"Am. J. Pathol."},{"issue":"3","key":"C9FO00189A-(cit15)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.alcohol.2013.01.005","volume":"47","author":"Kirpich","year":"2013","journal-title":"Alcohol"},{"issue":"1","key":"C9FO00189A-(cit16)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1053\/j.gastro.2014.09.014","volume":"148","author":"Chen","year":"2015","journal-title":"Gastroenterology"},{"issue":"6","key":"C9FO00189A-(cit17)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"e0130346","DOI":"10.1371\/journal.pone.0130346","volume":"10","author":"Meikle","year":"2015","journal-title":"PLoS One"},{"issue":"2","key":"C9FO00189A-(cit18)\/*[position()=1]","first-page":"223","volume":"37","author":"Engen","year":"2015","journal-title":"Alcohol Res."},{"issue":"8","key":"C9FO00189A-(cit19)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"H1912","DOI":"10.1111\/1750-3841.12943","volume":"80","author":"Fu","year":"2015","journal-title":"J. Food Sci."},{"issue":"1","key":"C9FO00189A-(cit20)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.aca.2011.01.034","volume":"689","author":"Han","year":"2011","journal-title":"Anal. Chim. Acta"},{"issue":"4","key":"C9FO00189A-(cit21)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1139\/cjpp-2014-0536","volume":"93","author":"Wang","year":"2015","journal-title":"J. Physiol. Pharmacol."},{"issue":"2","key":"C9FO00189A-(cit22)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.intimp.2015.02.012","volume":"25","author":"Wang","year":"2015","journal-title":"Int. Immunopharmacol."},{"key":"C9FO00189A-(cit23)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"e1369343","DOI":"10.1080\/16546628.2017.1369343","volume":"61","author":"Lu","year":"2017","journal-title":"Food Nutr. Res."},{"issue":"8","key":"C9FO00189A-(cit24)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2897","DOI":"10.1007\/s00394-017-1561-5","volume":"57","author":"Singh","year":"2018","journal-title":"Eur. J. Nutr."},{"issue":"3","key":"C9FO00189A-(cit25)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1038\/ijo.2015.197","volume":"40","author":"Singh","year":"2015","journal-title":"Int. J. Obes."},{"issue":"1","key":"C9FO00189A-(cit26)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.aca.2011.01.034","volume":"689","author":"Han","year":"2011","journal-title":"Anal. Chim. Acta"},{"issue":"9","key":"C9FO00189A-(cit27)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1111\/j.1530-0277.2002.tb02688.x","volume":"26","author":"Sierksma","year":"2002","journal-title":"Alcohol.: Clin. Exp. Res."},{"issue":"1","key":"C9FO00189A-(cit28)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"e53028","DOI":"10.1371\/journal.pone.0053028","volume":"8","author":"Bullotterson","year":"2013","journal-title":"PLoS One"},{"issue":"6","key":"C9FO00189A-(cit29)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1007\/s00204-009-0432-0","volume":"83","author":"Cederbaum","year":"2009","journal-title":"Arch. Toxicol."},{"key":"C9FO00189A-(cit30)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4364","DOI":"10.1039\/C7FO00907K","volume":"8","author":"Lu","year":"2017","journal-title":"Food Funct."},{"key":"C9FO00189A-(cit31)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"4153","DOI":"10.1039\/C8FO02379D","volume":"10","author":"Lu","year":"2019","journal-title":"Food Funct."},{"key":"C9FO00189A-(cit32)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2035","DOI":"10.1136\/gutjnl-2016-312729","volume":"65","author":"Tilg","year":"2016","journal-title":"Gut"},{"issue":"11","key":"C9FO00189A-(cit33)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1111\/j.1572-0241.1998.00600.x","volume":"93","author":"Aiba","year":"1998","journal-title":"Am. J. Gastroenterol."},{"issue":"1","key":"C9FO00189A-(cit34)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1053\/j.gastro.2014.09.014","volume":"148","author":"Chen","year":"2015","journal-title":"Gastroenterology"},{"key":"C9FO00189A-(cit35)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1111\/j.1572-0241.1999.00797.x","volume":"94","author":"Keshavarzian","year":"1999","journal-title":"Am. J. Gastroenterol."},{"issue":"1","key":"C9FO00189A-(cit36)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/biom6010001","volume":"6","author":"Kirpich","year":"2016","journal-title":"Biomolecules"},{"issue":"6","key":"C9FO00189A-(cit37)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1002\/hep.27406","volume":"60","author":"Wang","year":"2015","journal-title":"Hepatology"},{"key":"C9FO00189A-(cit38)\/*[position()=1]","volume-title":"Reactive Oxygen Species (ROS) and Liver Disease Therapy","volume":"12","author":"Bellanti","year":"2014","unstructured":"F. Bellanti  ,  J.Sastre  and  G.Serviddio ,  Reactive Oxygen Species (ROS) and Liver Disease Therapy ,  Springer Berlin Heidelberg ,  2014 , vol.  12 , pp.  4178\u20134141"},{"issue":"4","key":"C9FO00189A-(cit39)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1002\/oby.20274","volume":"21","author":"Miyata","year":"2013","journal-title":"Obesity"},{"issue":"5","key":"C9FO00189A-(cit40)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1053\/j.gastro.2011.09.002","volume":"141","author":"Gao","year":"2011","journal-title":"Gastroenterology"},{"issue":"1","key":"C9FO00189A-(cit41)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1172\/JCI88881","volume":"127","author":"Koyama","year":"2017","journal-title":"J. Clin. Invest."},{"issue":"3","key":"C9FO00189A-(cit42)\/*[position()=1]","first-page":"1","volume":"46","author":"Tang","year":"2018","journal-title":"Urolithiasis"},{"key":"C9FO00189A-(cit43)\/*[position()=1]","volume-title":"Encyclopedia of Metagenomics","author":"Wang","year":"2013","unstructured":"J. Wang  ,  Human Gut Microbial Gene by Metagenomic Sequencing , in  Encyclopedia of Metagenomics , ed.  K. Nelson ,  Springer ,  New York, NY ,  2013"},{"issue":"1","key":"C9FO00189A-(cit44)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1186\/s12944-016-0252-1","volume":"15","author":"Zhou","year":"2016","journal-title":"Lipids Health Dis."},{"key":"C9FO00189A-(cit45)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/nature08821","volume":"464","author":"Qin","year":"2010","journal-title":"Nature"},{"key":"C9FO00189A-(cit46)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.lfs.2018.01.008","volume":"195","author":"Wen","year":"2018","journal-title":"Life Sci."},{"issue":"1","key":"C9FO00189A-(cit47)\/*[position()=1]","first-page":"1","volume":"61","author":"Neyrinck","year":"2016","journal-title":"Mol. Nutr. Food Res."},{"issue":"7","key":"C9FO00189A-(cit48)\/*[position()=1]","doi-asserted-by":"crossref","first-page":"802","DOI":"10.3390\/nu10070802","volume":"10","author":"Hsiao-Yun","year":"2018","journal-title":"Nutrients"}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2019\/FO\/C9FO00189A","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:30:38Z","timestamp":1782883838000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/10\/10\/6385-6398\/645437"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":48,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2019,10,16]]}},"URL":"https:\/\/doi.org\/10.1039\/c9fo00189a","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019]]},"assertion":[{"value":"This document is Similarity Check deposited","name":"similarity_check","explanation":{"URL":"https:\/\/www.crossref.org\/services\/similarity-check\/"},"group":{"name":"similarity_check","label":"SIMILARITY CHECK"}},{"value":"Yalong Lu (ORCID)","URL":"http:\/\/orcid.org\/0000-0001-5792-4819","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Yalong Lu (ResearcherID)","URL":"http:\/\/www.researcherid.com\/rid\/J-9524-2017","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Xingbin Yang (ORCID)","URL":"http:\/\/orcid.org\/0000-0002-8039-0525","name":"identifier","group":{"name":"author_identifiers","label":"IDENTIFIERS"}},{"value":"Single-blind","order":2,"name":"peer_review_method","group":{"name":"peer_review_method","label":"PEER REVIEW METHOD"}},{"value":"Received 28 January 2019; Accepted 21 August 2019;  Accepted Manuscript published 23 August 2019;  Advance Article published 12 September 2019;  Version of Record published 16 October 2019","order":1,"name":"history","group":{"name":"publication_history","label":"PUBLICATION HISTORY"}}]}}